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PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor.
PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor.
产品描述 | PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor. |
体内活性 | PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) exhibits TGI(%) of 19.96% in the subcutaneous 4T1 murine breast cancer model in BALB/c mice[1]. PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) dose-dependently inhibits tumor growth in the Bl6F10 models with TGI% of 35.59% (30 mg/kg), 38.87% (60 mg/kg) and 47.35% (120 mg/kg), respectively[1]. |
分子量 | 469.504 |
分子式 | C27H26F3NO3 |
CAS No. | 2360909-50-6 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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