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Search Results for " synthetase "
Targets Recommended: Others

145

抑制剂 & 化合物

18

天然产物

1

化合物库

45

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2

同位素标记化合物

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Cat. No. Product Name
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T72505L CTP Synthetase-IN-1 Ammonium salt

CTPS-IN-1 Ammonium salt,CTP Synthetase-IN-1 Ammonium salt(2338811-71-3 Free base)

Others Others
CTP Synthetase-IN-1 Ammonium salt 是一种具有口服活性和高效性的胞苷 5'-三磷酸合成酶 (CTPS) 抑制剂,具有潜在的抗菌抗炎抗肿瘤活性,可用于研究 SARS-CoV-2病毒感染。
T72505 CTP Synthetase-IN-1

Others Others
CTP Synthetase-IN-1 是一种具有口服活性和高效性的胞苷 5'-三磷酸合成酶 (CTPS) 抑制剂,具有潜在的抗肿瘤活性,在炎症动物模型中显示出抗炎活性,抑制人 CTPS1 和人 CTPS2,可用于研究关节炎和类风湿性关节炎。
T10303 Aminoacyl tRNA synthetase-IN-1

Others Others
Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).
T74612 Aminoacyl tRNA synthetase-IN-2

Others Others
Aminoacyl tRNA synthetase-IN-2 (Compound 14) 是氨酰基-tRNA 合成酶 (aaRS) 抑制剂,可用于新型抗生素家族的开发。
T74932 Trypanothione synthetase-IN-1

Others Others
Trypanothione synthetase-IN-1 (Compound 1) 为一竞争性婴儿利什曼虫锥体胱甘肽合成酶(TryS)抑制剂,以三胺亚精胺为多胺S时,IC50值为14.8 μM。
T74933 Trypanothione synthetase-IN-2

Others Others
Trypanothione synthetase-IN-2 (Compound 3) 为竞争性婴儿利什曼虫锥虫胱甘肽合成酶 (TryS) 抑制剂,以三胺亚精胺作为多胺S时,IC50 值为5.4 μM。
T76124 Acyl coenzyme A synthetase

Others Others
Acyl coenzyme A synthetase (ACS),一种生化研究中常用的酶,主要通过两步硫酯化反应激活脂肪酸与辅酶A结合,形成酰基辅酶A。该过程为脂质代谢中的多种合成与分解代谢途径,以及参与TCA循环中的有氧呼吸提供了关键中间物。
T64056 Trypanothione synthetase-IN-4

Others Others
Trypanothione synthetase-IN-4 是一个 L. infantumTryS 抑制剂,其活性依赖于多胺底物的浓度。Trypanothione synthetase-IN-4 表现出较强的抗 leishmanicidal 效果 (EC50: 0.6 μM,SI (选择性指数): 35)。Trypanothione synthetase-IN-4 能够用于研究利什曼病。
T74934 Trypanothione synthetase-IN-3

Others Others
Trypanothione synthetase-IN-3是一种针对Trypanothione synthetase (TryS)的非竞争性混合双曲线抑制剂,其Ki值为0.8 μM。该化合物主要用于研究寄生虫,例如L. infantum。
T63688 Isoleucyl tRNA synthetase-IN-1

Others Others
Isoleucyl tRNA synthetase-IN-1 是选择性的、有效的靶向异亮基 tRNA 合成酶 (IleRS) 的抑制剂 (Ki: 88 nM)。
T63706 Isoleucyl tRNA synthetase-IN-2

Others Others
Isoleucyl tRNA synthetase-IN-2 是选择性的、有效的靶向异亮基 tRNA 合成酶 (IleRS) 的抑制剂 (Ki: 114 nM)。
T9533 BC-LI-0186

4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Others Others
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) 是选择性抑制亮氨酸 tRNA 合成酶与 Ras 相关的 GTP 结合蛋白 D 相互作用(IC50=46.11 nM)。BC-LI-0186能有效抑制肿瘤相关 MTOR 突变体的特性和雷帕霉素耐药癌细胞的生长,能够用于肺癌的相关研究。
T14141 AGI-24512

DNA DNA Damage/DNA Repair
AGI-24512 是一种具有高效性的蛋氨酸腺苷转移酶 2α (MAT2A) 抑制剂(IC50 :8 nM)。AGI-24512 在 MTAP 缺失的癌细胞中显示出抗增殖活性。AGI-24512 抑制 MAT2A 会在 MTAP 中诱导 DNA 损伤,常用抗癌化合物联用来研究癌症。
T11529 H3B-120

Others; Potassium Channel Membrane transporter/Ion channel; Others
H3B-120 是高选择性,竞争性的氨基甲酰磷酸合成酶 1 变构抑制剂,IC50为 1.5 μM,Ki 为 1.4 μM。它具有抗癌活性。
T8356 FPL 62064

Lipoxygenase; COX Immunology/Inflammation; Metabolism; Neuroscience
FPL 62064 是 5-脂氧合酶和COX 双重抑制剂,具有抗炎活性,对 RBL-1 胞质 5-脂氧合酶和前列腺素合成酶 (环氧化酶) 的IC50值分别为 3.5 和 3.1 μM。
T0767 Sulfapyridine

磺胺吡啶,Sulfidine,Sulfidin,2-Sulfapyridine

Antibacterial; Antibiotic; Autophagy Autophagy; Microbiology/Virology
Sulfapyridine (2-Sulfapyridine) 是一种磺酰胺类抗生素,是 Sulfasalazine 的代谢产物。它抑制重组 P. carinii 二氢蝶呤合成酶,IC50为 0.18 μM。它具有抗菌,抗炎和抗风湿作用。
T33565 NAAD sodium salt

NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD

Others Others
NAAD sodium salt (NAAD Na salt) 是烟酰胺腺嘌呤二核苷酸合酶的底物,可用于研究底物的特异性和动力学。
T4380 Ac-CoA Synthase Inhibitor1

ACSS2 inhibitor

RSV; Fatty Acid Synthase Metabolism; Microbiology/Virology
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) 是一种可逆的醋酸盐依赖性乙酰辅酶 A 合成酶 2 抑制剂,IC50为 0.6 µM,可抑制呼吸道合胞病毒。
T40656 Chlorobenzuron

Others Others
Chlorobenzuron 是一种有效的几丁质合成酶抑制剂,具有杀虫的活性,可以抑制幼虫发育和蛹化的作用。
T6120 Pralatrexate

Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙

Apoptosis; DHFR; Antifolate; TAM Receptor Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
Pralatrexate (10-Propargyl-10-deazaaminopterin) 是一种抗叶酸剂,也是二氢叶酸还原酶抑制剂,Ki 值为 13.4 pM。它具有抗肿瘤活性,可研究复发/难治性 T 细胞淋巴瘤。它是叶酰聚谷氨酸合成酶的底物,具有改善的细胞摄取和保留能力。
T0005 Aspirin

阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA

Mitophagy; Virus Protease; COX; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Aspirin (Acetylsalicylic Acid) 是一种选择性 COX 抑制剂,具有多种药理活性。它是组蛋白去乙酰化酶抑制剂,可上调细胞周期阻滞蛋白 p21,抑制携带 COX-1 的卵巢 Y 细胞。 它还抑制 HUVEC 和新生大鼠心室心肌细胞中 COX-2 的表达,分别减少 PG 的产生和 ERK 和 NF-KB 的下调。
T78227 L-Methioninamide hydrochloride

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
L-Methioninamide hydrochloride 是一种有效的甲硫氨酰-tRNA 合成酶 (Methionyl-tRNA synthetase) 抑制剂,能够降低CDDP毒性。
T22225 4-Methylsalicylic acid

Others Others
4-Methylsalicylic acid 用于抑制中链酰基辅酶A 合成酶。
T11919 LysRs-IN-1

9-carboxymethylguanine

Others Others
LysRs-IN-1是一种赖氨酰-tRNA 合成酶(LysRs)的抑制剂。
T0123 Sulfanilamide

Sulphanilamide,磺胺,UK-124

Antibacterial; Antibiotic; Autophagy Autophagy; Microbiology/Virology
Sulfanilamide (UK-124) 是一种细菌二氢蝶酸合成酶抑制剂,IC50为320 μM。
T20121 L-Albizziin

NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin,L-脲基丙氨酸

Glutaminase Proteases/Proteasome
L-Albizziin (L-beta-Ureidoalanine) 是一种巯基试剂,是一种谷氨酰胺酶抑制剂,可用于研究癌症。
T0264 Zomepirac sodium salt

Zomepirac Sodium,佐美酸钠,McN-2783-21-98

PGE Synthase; PDE Immunology/Inflammation; Metabolism
Zomepirac sodium salt (McN-2783-21-98) 是前列腺素合成酶抑制剂。它是一种非甾体抗炎药,但能够导致免疫介导的肝损伤。
T7708 DL-Buthionine-(S,R)-sulfoximine

Butionine sulfoximine,丁基硫,NSC 381100,D,L-Buthionine-(S,R)-sulfoximine

Others; Ferroptosis Apoptosis; Others
DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) 是 γ-谷氨酰半胱氨酸合成酶的抑制剂,用于治疗实体瘤。
T11497 Ganfeborole HCl

GSK3036656 HCl,GSK656 HCl

Antibacterial Microbiology/Virology
Ganfeborole HCl (GSK3036656 HCl) 是一种具有抗结核活性的小分子化合物,是结核分枝杆菌(Mtb)亮氨酰-tRNA 合成酶(LeuRS;IC50:0.2 μM)的抑制剂。
T41299 L-Methionine-DL-sulfoximine

MSX,MSO

Others Others
L-Methionine-DL-sulfoximine (MSO) 抑制谷氨酰胺合成酶,主要在代谢和形态上影响星形胶质细胞。L-Methionine-DL-sulfoximine 可用于惊厥相关研究。
T10098 PGS-IN-1

KME-4

Lipoxygenase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
PGS-IN-1 (KME-4)是一种前列腺素合成酶抑制剂,IC50=0.28 μM。它也可抑制5-脂肪氧合酶的活性,IC50=1.05 μM。
T4045 Epetraborole hydrochloride

GSK2251052 hydrochloride

Antibacterial Microbiology/Virology
Epetraborole hydrochloride (GSK2251052 hydrochloride) 是一个新型 LeuRS 抑制剂,通过绑定 leucyl-tRNA 合成酶终端的腺苷核糖抑制蛋白合成,可研究 Gram-negative 细菌引起的感染。
T0789 PMSF

Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride,苯甲基磺酰氟

Serine Protease; Cysteine Protease Proteases/Proteasome
PMSF (Phenylmethylsulfonyl fluoride) 是一种丝氨酸/半胱氨酸蛋白酶不可逆抑制剂,常用于制备细胞裂解物。
T35803 C14 Ceramide (d18:1/14:0)

Cer(d18:1/14:0),N-Myristoyl-D-sphingosine

C14 Ceramide (d18:1/14:0) 是由神经酰胺合成酶 6 生成的一种内源性神经酰胺,可用于研究帕金森。
T0699 Sulfamonomethoxine

磺胺间甲氧嘧啶,磺胺间甲氧嘧啶钠

Antibacterial; Antibiotic Microbiology/Virology
Sulfamonomethoxine 是一种磺胺类抗菌剂。它可研究血液动力学,竞争性抑制剂二氢叶酸合成,从而阻断叶酸合成。
T69730 F092

PGE Synthase Immunology/Inflammation
F092 是一种高效的造血前列腺素 D 合成酶 (H-PGDS) 抑制剂, 可以用于研究过敏性炎症和与血管相关的疾病。
T7439 3-Methoxybenzamide

3-MBA,3-甲氧基苯甲酰胺

PARP; Antibacterial; Transferase Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
3-Methoxybenzamide (3-MBA) 是一种多聚 ADP-核糖合成酶的竞争性抑制剂,可抑制枯草芽孢杆菌的细胞分裂,诱导细胞凋亡。它可促进蓝薯植株的生长、微瘤化和转化效率。
T6236 Ozagrel

奥扎格雷,OKY-046,Domenan

Thrombin; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
Ozagrel (Domenan) 是血栓烷 A2(TXA2) 合酶抑制剂,可抑制哮喘。它也是一种抗血小板剂,可选择性抑制人血小板聚集,IC50为 53.12 μM。
T29457L 5-Hydroxydecanoate sodium

Potassium Channel Membrane transporter/Ion channel
5-Hydroxydecanoate sodium 是一种选择性 ATP 敏感的 K+ (KATP) 通道阻滞剂,IC50 约为 30 μM。 它是线粒体外膜酰基辅酶A 合成酶的底物,具有抗氧化性。
T9732 VY-3-135

Fatty Acid Synthase Metabolism
VY-3-135 是口服有效的乙酰辅酶 A 合成酶 2 (ACSS2)选择性 抑制剂,IC50为 44 nM,对重组人 ACSS1 或 ACSS3 没有抑制活性。它有效抑制 ACSS2 依赖性脂肪酸代谢,但对肿瘤中的基因表达没有影响。
T15608 Jarin-1

Others Others
Jarin-1 是一种茉莉酸-酰胺基合成酶 (JAR1) 抑制剂,IC50 为 3.8 μM。Jarin-1 特异性抑制拟南芥和其他植物中具有生物活性的 JA-Ile 的生物合成。
T14387 AZD9898

Leukotriene Receptor GPCR/G Protein
AZD9898 是一种白三烯-C4 合成酶抑制剂,IC50 为 0.28 nM。 AZD9898 可用于哮喘研究。 AZD9898 减轻 GABA 结合和肝毒性信号。
T6625 Ozagrel hydrochloride

Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl

Thrombin; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
Ozagrel hydrochloride (OKY-046 HCl) 是一种选择性血栓素 A(2) 合成酶抑制剂,用于改善术后脑血管收缩和伴随的脑缺血。它是一种抗血小板剂,可选择性抑制人血小板聚集,IC50为 53.12 μM。
T9085 JFD01307SC

[(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]

Antibacterial Microbiology/Virology
JFD01307SC ([(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]) 是一种谷氨酰胺合成酶抑制剂。 它是抗结核剂,可作为 L-谷氨酸盐的模拟物,靶向参与谷氨酰胺生物合成的酶。
T10783 CGS 15435

PPAR DNA Damage/DNA Repair; Metabolism
CGS 15435是一种有效的血栓素(TxA2)合成酶抑制剂(IC50: 1 nM)。CGS 15435作用于 PGI2合成酶、环氧合酶和脂合酶比作用于血栓素合成酶选择性低得多。
T5371 L-BUTHIONINE-(S,R)-SULFOXIMINE

L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺

Others; Ferroptosis Apoptosis; Others
L-Buthionine-(S,R)-sulfoximine 是一种 γ-谷氨酰半胱氨酸合成酶抑制剂,具有细胞渗透性、不可逆性和快速起效性。L-Buthionine-(S,R)-sulfoximine 通过消耗 GSH 诱导细胞中的氧化应激。
T61194 D75-4590

Others Others
D75-4590是一种β-1,6-葡聚糖抑制剂。由于葡聚糖是细胞壁的主要成分,特别是β-1,6-葡聚糖,D75-4590可以通过抑制其合成酶来对抗真菌感染。
T60060 ACSS2-IN-2

MTB-9655

Fatty Acid Synthase Metabolism
ACSS2-IN-2 (MTB-9655) 是酰基辅酶 A 合成酶短链家族成员 2 (ACSS2) 抑制剂。ACSS2-IN-2 可抑制 ACSS2 活性,IC50 为 3.8 nM。ACSS2-IN-2 可用于多种疾病的研究,如病毒感染、代谢紊乱、神经精神疾病、炎症/自身免疫疾病和癌症。
T36866 3-Deazauridine

4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮,NSC 126849

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
3-Deazauridine (NSC-126849) 是一种尿苷的结构类似物,通过竞争性抑制胞苷三磷酸合成酶来抑制胞苷-5'-三磷酸的生物合成,这种合成酶被认为是这种核苷类似物的主要作用方式。
T23601 ABC1183

ABC 1183,ABC-1183

GSK-3; CDK Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells
ABC1183是一种抑制GSK3α, GSK3β和CDK9的新型二氨基噻唑。ABC1183通过诱导G2/M 阻滞和改变GSK3、糖原合成酶、β-catenin 磷酸化和MCL1表达降低细胞存活率来抑制多种癌细胞株的生长,并具有口服活性。

化合物

CTP Synthetase-IN-1 Ammonium salt
Cat.No: T72505L
Synonym: CTPS-IN-1 Ammonium salt,CTP Synthetase-IN-1 Ammonium salt(2338811-71-3 Free base)
Target: Others
CTP Synthetase-IN-1
Cat.No: T72505
Synonym:
Target: Others
Aminoacyl tRNA synthetase-IN-1
Cat.No: T10303
Synonym:
Target: Others
Aminoacyl tRNA synthetase-IN-2
Cat.No: T74612
Synonym:
Target: Others
Trypanothione synthetase-IN-1
Cat.No: T74932
Synonym:
Target: Others
Trypanothione synthetase-IN-2
Cat.No: T74933
Synonym:
Target: Others
Acyl coenzyme A synthetase
Cat.No: T76124
Synonym:
Target: Others
Trypanothione synthetase-IN-4
Cat.No: T64056
Synonym:
Target: Others
Trypanothione synthetase-IN-3
Cat.No: T74934
Synonym:
Target: Others
Isoleucyl tRNA synthetase-IN-1
Cat.No: T63688
Synonym:
Target: Others
Isoleucyl tRNA synthetase-IN-2
Cat.No: T63706
Synonym:
Target: Others
BC-LI-0186
Cat.No: T9533
Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide
Target: Others
AGI-24512
Cat.No: T14141
Synonym:
Target: DNA
H3B-120
Cat.No: T11529
Synonym:
Target: Others, Potassium Channel
FPL 62064
Cat.No: T8356
Synonym:
Target: Lipoxygenase, COX
Sulfapyridine
Cat.No: T0767
Synonym: 磺胺吡啶,Sulfidine,Sulfidin,2-Sulfapyridine
Target: Antibacterial, Antibiotic, Autophagy
NAAD sodium salt
Cat.No: T33565
Synonym: NAAD钠盐,NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
Target: Others
Ac-CoA Synthase Inhibitor1
Cat.No: T4380
Synonym: ACSS2 inhibitor
Target: RSV, Fatty Acid Synthase
Chlorobenzuron
Cat.No: T40656
Synonym:
Target: Others
Pralatrexate
Cat.No: T6120
Synonym: Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙
Target: Apoptosis, DHFR, Antifolate, TAM Receptor
Aspirin
Cat.No: T0005
Synonym: 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA
Target: Mitophagy, Virus Protease, COX, Autophagy
L-Methioninamide hydrochloride
Cat.No: T78227
Synonym:
Target: DNA/RNA Synthesis
4-Methylsalicylic acid
Cat.No: T22225
Synonym:
Target: Others
LysRs-IN-1
Cat.No: T11919
Synonym: 9-carboxymethylguanine
Target: Others
Sulfanilamide
Cat.No: T0123
Synonym: Sulphanilamide,磺胺,UK-124
Target: Antibacterial, Antibiotic, Autophagy
L-Albizziin
Cat.No: T20121
Synonym: NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin,L-脲基丙氨酸
Target: Glutaminase
Zomepirac sodium salt
Cat.No: T0264
Synonym: Zomepirac Sodium,佐美酸钠,McN-2783-21-98
Target: PGE Synthase, PDE
DL-Buthionine-(S,R)-sulfoximine
Cat.No: T7708
Synonym: Butionine sulfoximine,丁基硫,NSC 381100,D,L-Buthionine-(S,R)-sulfoximine
Target: Others, Ferroptosis
Ganfeborole HCl
Cat.No: T11497
Synonym: GSK3036656 HCl,GSK656 HCl
Target: Antibacterial
L-Methionine-DL-sulfoximine
Cat.No: T41299
Synonym: MSX,MSO
Target: Others
PGS-IN-1
Cat.No: T10098
Synonym: KME-4
Target: Lipoxygenase, Prostaglandin Receptor
Epetraborole hydrochloride
Cat.No: T4045
Synonym: GSK2251052 hydrochloride
Target: Antibacterial
PMSF
Cat.No: T0789
Synonym: Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride,苯甲基磺酰氟
Target: Serine Protease, Cysteine Protease
C14 Ceramide (d18:1/14:0)
Cat.No: T35803
Synonym: Cer(d18:1/14:0),N-Myristoyl-D-sphingosine
Target:
Sulfamonomethoxine
Cat.No: T0699
Synonym: 磺胺间甲氧嘧啶,磺胺间甲氧嘧啶钠
Target: Antibacterial, Antibiotic
F092
Cat.No: T69730
Synonym:
Target: PGE Synthase
3-Methoxybenzamide
Cat.No: T7439
Synonym: 3-MBA,3-甲氧基苯甲酰胺
Target: PARP, Antibacterial, Transferase
Ozagrel
Cat.No: T6236
Synonym: 奥扎格雷,OKY-046,Domenan
Target: Thrombin, Prostaglandin Receptor
5-Hydroxydecanoate sodium
Cat.No: T29457L
Synonym:
Target: Potassium Channel
VY-3-135
Cat.No: T9732
Synonym:
Target: Fatty Acid Synthase
Jarin-1
Cat.No: T15608
Synonym:
Target: Others
AZD9898
Cat.No: T14387
Synonym:
Target: Leukotriene Receptor
Ozagrel hydrochloride
Cat.No: T6625
Synonym: Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl
Target: Thrombin, Prostaglandin Receptor
JFD01307SC
Cat.No: T9085
Synonym: [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]
Target: Antibacterial
CGS 15435
Cat.No: T10783
Synonym:
Target: PPAR
L-BUTHIONINE-(S,R)-SULFOXIMINE
Cat.No: T5371
Synonym: L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺
Target: Others, Ferroptosis
D75-4590
Cat.No: T61194
Synonym:
Target: Others
ACSS2-IN-2
Cat.No: T60060
Synonym: MTB-9655
Target: Fatty Acid Synthase
3-Deazauridine
Cat.No: T36866
Synonym: 4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮,NSC 126849
Target: Nucleoside Antimetabolite/Analog
ABC1183
Cat.No: T23601
Synonym: ABC 1183,ABC-1183
Target: GSK-3, CDK
Cat. No. Product Name Target Signaling Pathways
T6856 Halofuginone

卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
Halofuginone (RU-19110) 是Febrifugine 的衍生物,是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂,可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
T6942 Picolinamide

2-Pyridinecarboxamide,2-Carbamoylpyridine,2-吡啶甲酰胺,2-Picolinamide,Picolinoylamide

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Picolinamide (Picolinoylamide) 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。
T7481 2-Hydroxycaprylic acid

2-hydroxyoctanoic acid,2-羟基辛酸

Others Others
2-Hydroxyoctanoic acid 是中链酰基辅酶 A 合成酶抑制剂 (Ki:500 μM)。
TN1800 Isosakuranin

Others Others
Isosakuranin 是一种提取自Paliurus ramosissimus果实中的天然产物,具有抗糖尿病作用。
T1465 Mupirocin

Pseudomonic acid,莫匹罗星,BRL-4910A

DNA/RNA Synthesis; Antibacterial; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起抗菌作用。
T21494 Oligomycin

寡霉素

HIF Angiogenesis; Chromatin/Epigenetic
Oligomycin 是一种抗真菌抗生素,是 H+-ATP 合成酶的抑制剂。Oligomycin 能够阻断氧化磷酸化和电子传递链。Oligomycin 对缺氧性肿瘤细胞 HIF-1alpha 表达具有抑制作用。
T2O2774 L-Asparagine

alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine

Endogenous Metabolite Metabolism
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。
T4735 2'-Deoxyuridine 5'-monophosphate disodium

2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt 能够被双底物酶胸苷酸合酶(TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。
T5515 Hemin

氯化血红素,Hemin chloride

Mitophagy; Ferroptosis; Autophagy Apoptosis; Autophagy
Hemin (Hemin chloride) 是一种含有氯的含铁卟啉,一种血红素加氧酶 (HO)-1 诱导剂。Hemin 对卟啉病具有治疗活性,可以减少患者的血红素缺乏,从而通过生物化学反馈抑制 δ-氨基乙酰丙酸合成酶的活性。
TN1982 Neoglycyrol

Others Others
Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到,具有潜在心肌保护作用。
TL0005 3,5-O-Dicaffeoylquinic acid

Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid

Others Others
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) 能够改善由三甲基锡诱导的学习和记忆缺陷。
T5244 Aminomalonic acid

2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Others; Endogenous Metabolite Metabolism; Others
Aminomalonic acid 是氨基内源性代谢产物,在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M,小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
T5267 N-Acetyl-L-glutamic acid

Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸,是动物细胞培养基的组成成分,是一种酿酒酵母和人类的代谢物。
T3524 Halofuginone hydrobromide

卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
Halofuginone hydrobromid 是Febrifugine 的衍生物,是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂,并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T37753 Aureusimine B

Cysteine Protease; Antibacterial Microbiology/Virology; Proteases/Proteasome
Aureusimine B 是一种钙蛋白酶抑制剂,由金黄色葡萄球菌生物膜产生,可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。
T10582 Borrelidin

Treponemycin

Others Others
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
T13199 Triacsin C

WS 1228A,FR 900190

Others Others
Triacsin C (WS 1228A) 来自金黄色链霉菌 (Streptomyces aureofaciens) ,是一种花生四烯酰辅酶A合成酶和非特异性长链酰辅酶A合成酶的差异抑制剂,抗动脉粥样硬化活性,抑制 ACSL 活性, 抑制 TAG 积聚成脂滴 (LD) 。Triacsin C 可用于研究轮状病毒感染和阿尔茨海默症。
TN1378 α-Viniferin

ALPHA-VINIFERIN,Alpha-葡萄素

P450; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism
α-Viniferin 也称为2-芳基苯并呋喃类黄酮,是前列腺素H2合成酶抑制剂。具有抗阿尔茨海默病、抗结核、抗肿瘤、抗炎、抗糖尿病等多种药理活性

天然产物

Halofuginone
Cat.No: T6856
Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Picolinamide
Cat.No: T6942
Synonym: 2-Pyridinecarboxamide,2-Carbamoylpyridine,2-吡啶甲酰胺,2-Picolinamide,Picolinoylamide
Target: PARP
2-Hydroxycaprylic acid
Cat.No: T7481
Synonym: 2-hydroxyoctanoic acid,2-羟基辛酸
Target: Others
Isosakuranin
Cat.No: TN1800
Synonym:
Target: Others
Mupirocin
Cat.No: T1465
Synonym: Pseudomonic acid,莫匹罗星,BRL-4910A
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
Oligomycin
Cat.No: T21494
Synonym: 寡霉素
Target: HIF
L-Asparagine
Cat.No: T2O2774
Synonym: alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine
Target: Endogenous Metabolite
2'-Deoxyuridine 5'-monophosphate disodium
Cat.No: T4735
Synonym: 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt
Target: Others, Endogenous Metabolite
Hemin
Cat.No: T5515
Synonym: 氯化血红素,Hemin chloride
Target: Mitophagy, Ferroptosis, Autophagy
Neoglycyrol
Cat.No: TN1982
Synonym:
Target: Others
3,5-O-Dicaffeoylquinic acid
Cat.No: TL0005
Synonym: Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid
Target: Others
Aminomalonic acid
Cat.No: T5244
Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate
Target: Others, Endogenous Metabolite
N-Acetyl-L-glutamic acid
Cat.No: T5267
Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid
Target: Others, Endogenous Metabolite
Halofuginone hydrobromide
Cat.No: T3524
Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Aureusimine B
Cat.No: T37753
Synonym:
Target: Cysteine Protease, Antibacterial
Borrelidin
Cat.No: T10582
Synonym: Treponemycin
Target: Others
Triacsin C
Cat.No: T13199
Synonym: WS 1228A,FR 900190
Target: Others
α-Viniferin
Cat.No: TN1378
Synonym: ALPHA-VINIFERIN,Alpha-葡萄素
Target: P450, NO Synthase, Prostaglandin Receptor
Cat. No. Product Name Species Expression System
TMPY-05305 alanyl-tRNA synthetase Protein, Human, Recombinant (His)

alanyl-tRNA synthetase,CMT2N

Human Baculovirus Insect Cells
alanyl-tRNA synthetase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 109.2 kDa and the accession number is P49588.
TMPY-02441 alanyl-tRNA synthetase Protein, Mouse, Recombinant (His)

sti,C76919,AI316495,alanyl-tRNA synthetase

Mouse Baculovirus Insect Cells
alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is Q8BGQ7.
TMPY-01461 EMAP-II/AIMP1 Protein, Human, Recombinant (His)

SCYE1,p43,EMAPII,aminoacyl tRNA synthetase complex-...

Human E. coli
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPJ-00979 GSH-S Protein, Human, Recombinant (His)

Glutathione Synthetase,GSS,GSH-S,GSH Synthetase...

Human E. coli
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...
TMPJ-00989 MTHFS Protein, Human, Recombinant (His)

5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...

Human E. coli
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas...
TMPY-03393 DARS Protein, Human, Recombinant (His)

aspartyl-tRNA synthetase,HBSL,aspRS

Human E. coli
Aspartate tRNA ligase 1, also known as DARS, is part of a multienzyme complex of aminoacyl-tRNA synthetases. It belongs to the class-II aminoacyl-tRNA synthetase family. DARS charges its cognate tRNA with aspartate during protein biosynthesis. DARS catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid(AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
TMPY-05413 HARS/HisRS Protein, Human, Recombinant (His)

histidyl-tRNA synthetase,USH3B,HRS

Human Baculovirus Insect Cells
HARS/HisRS Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is P12081-1.
TMPY-04768 PRPS2 Protein, Human, Recombinant (His)

PRPS2,PRSII,phosphoribosyl pyrophosphate synthetase...

Human E. coli
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine...
TMPH-02488 ACSS2 Protein, Mouse, Recombinant (His)

Propionate--CoA ligase,AceCS1,Acyl-activating enzyme,Acetyl-...

Mouse E. coli
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower affinity. ACSS2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82.9 kDa and the accession number is Q9QXG4.
TMPY-01427 AACS Protein, Human, Recombinant (His)

SUR-5,acetoacetyl-CoA synthetase,ACSF1

Human Baculovirus Insect Cells
Acetoacetyl-CoA Synthetase (AACS) is a novel cytosolic ketone body (acetoacetate)-specific ligase. The AACS in adipose tissue plays an important role in utilizing ketone body for the fatty acid-synthesis during adipose tissue development. It had been improved that Acetoacetyl-CoA Synthetase is an essential enzyme for the synthesis of fatty acid and cholesterol from ketone bodies, was found to be highly expressed in mouse adipose tissue, and GC box and C/EBPs motif were crucial for AACS promoter ...
TMPY-03448 AARSD1 Protein, Human, Recombinant (His)

AARSD1,alanyl-tRNA synthetase domain containing 1

Human E. coli
AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcript variants have been described for AARSD1: NM_25267.3, NM_113642.2, NM_1142653.1 and NM_1142654.1. It has been determined that the latter two variants represent a distinct upstream locus, which is now represented by GeneID:1885848 (PTGES3L), while the former two variants rep...
TMPJ-00855 GLUL Protein, Human, Recombinant (His)

GLUL,GS,Glutamine Synthetase,Glutamate-Ammonia Liga...

Human E. coli
Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.
TMPH-00877 ACSS1 Protein, Human, Recombinant (His)

Acetate--CoA ligase 2,KIAA1846,Acetyl-coenzyme A synthet...

Human P. pastoris (Yeast)
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. ACSS1 Protein, Human, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 73.6 kD...
TMPJ-01122 KARS Protein, Human, Recombinant (His)

Lysine--tRNA Ligase,Lysyl-tRNA Synthetase,LysRS,KAR...

Human HEK293 Cells
Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, which is required for nuclear localization, is involved in the interaction with DARS, but has a repulsive role in the binding to EEF1A1. A central domain (208-259) is involved in homodimerization and is required for interaction with HIV-1 GAG and incorporation into virions. KARS c...
TMPH-00876 ACSS1 Protein, Human, Recombinant (E. coli, His)

Acetate--CoA ligase 2,Acetyl-coenzyme A synthetase ...

Human E. coli
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. ACSS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted...
TMPH-00629 Gamma-GCS Protein, E. coli, Recombinant (His & SUMO)

Glutamate--cysteine ligase,Gamma-ECS,gshA,Gamma-glutamylcyst...

E. coli E. coli
N/A. Gamma-GCS Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.3 kDa and the accession number is P0A6W9.
TMPH-01565 IARS Protein, Human, Recombinant (His & Myc)

Isoleucine--tRNA ligase, cytoplasmic,Isoleucyl-tRNA synt...

Human E. coli
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
TMPY-03753 WARS Protein, Human, Recombinant (His)

tryptophanyl-tRNA synthetase,GAMMA-2,γ-2,IFI53,IFP5...

Human Baculovirus Insect Cells
WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. They catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in ...
TMPH-02741 IARS1 Protein, Mouse, Recombinant (His & Myc)

Isoleucyl-tRNA synthetase,Iars1,Isoleucine--tRNA li...

Mouse E. coli
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. IARS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.8 kDa and the accession number is Q8BU30.
TMPH-00438 GLUL Protein, Cricetulus griseus, Recombinant (His)

Glutamine synthetase,GLUL,Glutamate--ammonia ligase...

Chinese hamster E. coli
GLUL Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli.
TMPH-02279 YARS1 Protein, Human, Recombinant (GST)

Tyrosine--tRNA ligase, cytoplasmic,Tyrosyl-tRNA syntheta...

Human E. coli
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). YARS1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 86.0 kDa and the accession number is P54577.
TMPH-00796 gltX1 Protein, Helicobacter pylori, Recombinant (His)

Glutamyl-tRNA synthetase 1,gltX1,Glutamate--tRNA li...

Helicobacter pylori P. pastoris (Yeast)
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
TMPH-02150 SUCLG2 Protein, Human, Recombinant (His & SUMO)

Succinate--CoA ligase [GDP-forming] subunit beta, mitochondr...

Human E. coli
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. SUCLG2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system wit...
TMPH-03257 CPS1 Protein, Rat, Recombinant (His & Myc)

Carbamoyl-phosphate synthase [ammonia], mitochondrial,CPSase...

Rat E. coli
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.7 kDa and the accession number is P07756.
TMPH-02461 pylS Protein, Methanosarcina barkeri, Recombinant (His)

pylS,Pyrrolysine--tRNA ligase,Pyrrolysine--tRNA(Pyl) ligase,...

Methanosarcina barkeri E. coli
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. pylS Protein, Methanosarcina barkeri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.8 kDa and the accession number is Q46E77.
TMPH-01037 CPS1 Protein, Human, Recombinant (His)

CPS1,CPSase I,Carbamoyl-phosphate synthetase I,Carb...

Human E. coli
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.5 kDa and the accession number is P31327.
TMPH-02560 CPS1 Protein, Mouse, Recombinant (His)

Carbamoyl-phosphate synthetase I,CPS1,CPSase I,Carb...

Mouse E. coli
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
TMPH-03432 ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

mRNA transport-defective protein 7,Acetyl-CoA carboxylase,Fa...

Saccharomyces cerevisiae E. coli
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol...
TMPH-03431 ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,...

Saccharomyces cerevisiae E. coli
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m...
TMPH-03533 Ddl Protein, S. aureus, Recombinant (His & Myc)

ddl,D-alanylalanine synthetase,D-Ala-D-Ala ligase,D...

Staphylococcus aureus E. coli
Cell wall formation. Ddl Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.7 kDa and the accession number is P63891.
TMPY-03015 EMAP-II/AIMP1 Protein, Mouse, Recombinant

AIMP1,p43,Scye1,EMAPII,aminoacyl tRNA synthetase co...

Mouse E. coli
EMAP-II/AIMP1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q62386.
TMPH-02764 ACSL4 Protein, Mouse, Recombinant (His)

LACS 4,mACS4,Long-chain-fatty-acid--CoA ligase 4,Acsl4,Arach...

Mouse E. coli
ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

NS1 Protein

H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPH-01547 Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)

IFNA21,Interferon alpha-21,Interferon alpha-F

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-01544 Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)

Interferon alpha-H,Interferon alpha-14,Interferon lambda-2-H...

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-01546 Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)

Interferon alpha-T,Interferon alpha-88,IFNA17,Interferon alp...

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P01571.
TMPH-01545 Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)

Interferon alpha-16,Interferon alpha-WA,IFNA16

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P05015.
TMPH-01549 Interferon epsilon/IFNE Protein, Human, Recombinant (His)

IFNE,Interferon epsilon,Interferon epsilon-1

Human E. coli
Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections.
TMPH-00276 Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)

Interferon alpha-G,IFNAG,IFN-alpha7

Bovine E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P49877.
TMPJ-00611 SFP Protein, B.subtilis, Recombinant (His)

Surfactin synthase-activating enzyme,sfp,lpa-8,4'-phosphopan...

Bacillus subtilis E. coli
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
TMPJ-00780 IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

Interferon α-K,Interferon α-6,IFN α6,Interferon α-54,干扰素,Int...

Human HEK293 Cells
Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPJ-00800 BPGM Protein, Human, Recombinant (His)

3-Diphosphoglycerate Mutase,2,DPGM,Bisphosphoglycerate Mutas...

Human E. coli
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells...
TMPJ-00988 SEPHS1 Protein, Human, Recombinant (His)

water dikinase 1,SELD,Selenophosphate synthase 1,SEPHS1,SPS1...

Human HEK293 Cells
Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP....
TMPJ-00871 BAR Protein, S. hygroscopicus, Recombinant

bar,PPT N-acetyltransferase,Phosphinothricin-resistance prot...

Streptomyces hygroscopicus E. coli
Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant...
TMPY-02516 Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)

interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879,干扰...

Human HEK293 Cells
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen...

重组蛋白

alanyl-tRNA synthetase Protein, Human, Recombinant (His)
Cat.No: TMPY-05305
Species: Human
Expression System: Baculovirus Insect Cells
alanyl-tRNA synthetase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02441
Species: Mouse
Expression System: Baculovirus Insect Cells
EMAP-II/AIMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01461
Species: Human
Expression System: E. coli
GSH-S Protein, Human, Recombinant (His)
Cat.No: TMPJ-00979
Species: Human
Expression System: E. coli
MTHFS Protein, Human, Recombinant (His)
Cat.No: TMPJ-00989
Species: Human
Expression System: E. coli
DARS Protein, Human, Recombinant (His)
Cat.No: TMPY-03393
Species: Human
Expression System: E. coli
HARS/HisRS Protein, Human, Recombinant (His)
Cat.No: TMPY-05413
Species: Human
Expression System: Baculovirus Insect Cells
PRPS2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04768
Species: Human
Expression System: E. coli
ACSS2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02488
Species: Mouse
Expression System: E. coli
AACS Protein, Human, Recombinant (His)
Cat.No: TMPY-01427
Species: Human
Expression System: Baculovirus Insect Cells
AARSD1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03448
Species: Human
Expression System: E. coli
GLUL Protein, Human, Recombinant (His)
Cat.No: TMPJ-00855
Species: Human
Expression System: E. coli
ACSS1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00877
Species: Human
Expression System: P. pastoris (Yeast)
KARS Protein, Human, Recombinant (His)
Cat.No: TMPJ-01122
Species: Human
Expression System: HEK293 Cells
ACSS1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-00876
Species: Human
Expression System: E. coli
Gamma-GCS Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00629
Species: E. coli
Expression System: E. coli
IARS Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01565
Species: Human
Expression System: E. coli
WARS Protein, Human, Recombinant (His)
Cat.No: TMPY-03753
Species: Human
Expression System: Baculovirus Insect Cells
IARS1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02741
Species: Mouse
Expression System: E. coli
GLUL Protein, Cricetulus griseus, Recombinant (His)
Cat.No: TMPH-00438
Species: Chinese hamster
Expression System: E. coli
YARS1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02279
Species: Human
Expression System: E. coli
gltX1 Protein, Helicobacter pylori, Recombinant (His)
Cat.No: TMPH-00796
Species: Helicobacter pylori
Expression System: P. pastoris (Yeast)
SUCLG2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02150
Species: Human
Expression System: E. coli
CPS1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03257
Species: Rat
Expression System: E. coli
pylS Protein, Methanosarcina barkeri, Recombinant (His)
Cat.No: TMPH-02461
Species: Methanosarcina barkeri
Expression System: E. coli
CPS1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01037
Species: Human
Expression System: E. coli
CPS1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02560
Species: Mouse
Expression System: E. coli
ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)
Cat.No: TMPH-03432
Species: Saccharomyces cerevisiae
Expression System: E. coli
ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)
Cat.No: TMPH-03431
Species: Saccharomyces cerevisiae
Expression System: E. coli
Ddl Protein, S. aureus, Recombinant (His & Myc)
Cat.No: TMPH-03533
Species: Staphylococcus aureus
Expression System: E. coli
EMAP-II/AIMP1 Protein, Mouse, Recombinant
Cat.No: TMPY-03015
Species: Mouse
Expression System: E. coli
ACSL4 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02764
Species: Mouse
Expression System: E. coli
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
Cat.No: TMPY-02219
Species: H1N1
Expression System: E. coli
Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)
Cat.No: TMPH-01547
Species: Human
Expression System: E. coli
Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01544
Species: Human
Expression System: E. coli
Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)
Cat.No: TMPH-01546
Species: Human
Expression System: E. coli
Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)
Cat.No: TMPH-01545
Species: Human
Expression System: E. coli
Interferon epsilon/IFNE Protein, Human, Recombinant (His)
Cat.No: TMPH-01549
Species: Human
Expression System: E. coli
Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)
Cat.No: TMPH-00276
Species: Bovine
Expression System: E. coli
SFP Protein, B.subtilis, Recombinant (His)
Cat.No: TMPJ-00611
Species: Bacillus subtilis
Expression System: E. coli
IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00780
Species: Human
Expression System: HEK293 Cells
BPGM Protein, Human, Recombinant (His)
Cat.No: TMPJ-00800
Species: Human
Expression System: E. coli
SEPHS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00988
Species: Human
Expression System: HEK293 Cells
BAR Protein, S. hygroscopicus, Recombinant
Cat.No: TMPJ-00871
Species: Streptomyces hygroscopicus
Expression System: E. coli
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02516
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T13032 Sulfamonomethoxine-d4

Others Others
Sulfamonomethoxine D4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is an agent of long acting sulfonamide antibacterial, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
T36895 5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.

同位素标记化合物

Sulfamonomethoxine-d4
Cat.No: T13032
Synonym:
Target: Others
5-Fluorouracil-13C,15N2
Cat.No: T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
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