Asp-AMS

Name: Asp-AMS
Brand: TargetMol
SKU: T10386
Price: 253 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T10386Cas号 828288-98-8

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

Asp-AMS

还可以

产品编号 T10386Cas号 828288-98-8

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

规格	价格	库存
2 mg	¥ 2,490	5日内发货
25 mg	¥ 10,600	6-8周
50 mg	¥ 13,800	6-8周
100 mg	¥ 17,500	6-8周

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产品介绍

生物活性

产品描述

Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.

体外活性

Asp-AMS is a 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM) and a 35-fold lower competitor of human and bovine cyt-AspRSs (300 nM). Asp-AMS has also the highest inhibitory effect for the mitochondrial enzyme. Asp-AMS is the most active inhibitor with Ki values in the nanomolar range, with a stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS.

化学信息

分子量	461.41
分子式	C₁₄H₁₉N₇O₉S
CAS No.	828288-98-8
密度	2.14 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (216.73 mM)

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	2.1673 mL	10.8363 mL	21.6727 mL	108.3635 mL
5 mM	0.4335 mL	2.1673 mL	4.3345 mL	21.6727 mL
10 mM	0.2167 mL	1.0836 mL	2.1673 mL	10.8363 mL
20 mM	0.1084 mL	0.5418 mL	1.0836 mL	5.4182 mL
50 mM	0.0433 mL	0.2167 mL	0.4335 mL	2.1673 mL
100 mM	0.0217 mL	0.1084 mL	0.2167 mL	1.0836 mL