ptdins(4)p

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns-(4)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.

4-P-PDOT (4-phenyl-2- propionamidotetralin) 是一种选择性和亲和性的褪黑激素受体拮抗剂，可显著抵消褪黑激素介导的抗氧化作用。它对MT2的选择性是 MT1 的 300 倍以上。

[D-Pro4,D-Trp7,9,10] Substance P (4-11) 是一种tachykinin拮抗剂，具有高效性。

[Sar4] Substance P (4-11)为Substance P (4-11)的类似物，后者是Substance P (Substance P) C端片段并充当Substance P激动剂。

Substance P (4-11) 是 Substance P (Substance P ) 的 C 末端片段，是一种 Substance P 激动剂，对NK1受体具有高度选择性。

'(p-Iodo-Phe7)-ACTH (4-10)'为垂体前腺产生和分泌的肾上腺皮质激素(ACTH)衍生物，担任黑素皮质素(MC)受体拮抗剂角色，能够抑制α-黑素细胞刺激激素(α-MSH)引发的大鼠过度梳理行为。

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references and .

Butyraldehyde, 4-(p-aminophenoxy)-, diethyl acetal is a bioactive chemical.

Ammonium, (4-(p-ethyldimethylammoniophenyl)butyl)ethyldimethyl-, diiodide 可用于生命科学领域的相关研究。其产品编号为 T30012，CAS号为 63981-94-2。

m-Toluidine, alpha-((p-chlorophenyl)sulfonyl)-4-(octyloxy)- is a bioactive chemical.

4-Chloro-5-(p-tolyl)-1H-imidazole-2-carbonitrile 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T66379。

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6304，CAS号为 71781-79-8。

Pardaxin P 4，一种源自红海鲽鱼 (Red Sea Moses sole) 分泌物的抗菌肽，具有穿透生物膜的能力。该肽通过与不同成分的磷脂双层膜进行相互作用，并诱导孔形成及细胞毒性，展现其潜在的抗菌研究价值。

[DAla4] Substance P (4-11) 作为Substance P的衍生物，能够有效抑制125I-Bolton Hunter标记的Eledoisin（IC50值为0.5 μM）及125I-Bolton Hunter标记的Substance P (IC50值为0.15 μM)与大鼠大脑皮层膜之间的结合。

4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64550，CAS号为 1061214-06-9。

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.

m-Anisidine, 4-((5-p-tolylpentyl)oxy)- is a Drug / Therapeutic Agent.

4-(p-Biphenylyl)-3-hydroxybutyric acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124405。

Acetophenone, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

Acetanilide, 4'-(5-(p-(dimethylamino)phenoxy)pentyloxy)-N-ethyl- is a bioactive chemical.

Antimicrobial agent.

Phosphatidylinositol-(4,5)-P2(1,2-dipalmitoyl), a synthetic analog of natural phosphatidylinositol (PtdIns) with C16:0 fatty acids at the sn-1 and sn-2 positions, maintains the inositol and diacylglycerol (DAG) stereochemistry of its natural counterpart. Although phosphatidylinositol phosphates constitute a minor fraction of total membrane phospholipids, they are pivotal in initiating and propagating cellular signals. This compound mirrors the activity of the natural phosphatidylinositol produced by PtdIns-4-phosphate 5-kinase's action on PtdIns-(4)-P1. Its hydrolysis by phosphoinositide (PI)-specific phospholipase C yields inositol triphosphate (IP3) and DAG, crucial secondary messengers in a complex signal transduction pathway.

[D-Pro4,D-Trp7,9]Substance P(4-11)为高效Substance P 拮抗剂，可降低血浆醛固酮(ALDO)浓度。

Benzamide, N-(4-(p-aminophenoxy)butyl)- is a bioactive chemical.

2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a Carbohydrate Derivative.

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1024。

P-gp inhibitor 4 是一种选择性的 P-glycoprotein 调节剂，EC50值为 94 nM。P-gp inhibitor 4 增加药物通过胃肠道屏障的能力，恢复 doxorubicin 在耐药癌细胞中的毒性。

Super-chelating agent & MRI contrast agent

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-2-O-acetyl-5-(O-p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1038。

Nucleoside Derivatives - 2’-Modified nucleosides, 7-Deaza-purine nucleosides, Halo-nucleosides

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2871，CAS号为 349545-02-4。

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1021。

m-Anisidine, 4-((5-(p-nitrophenyl)pentyl)oxy)- is a bioactive chemical.

Ammonium, (4-(p-trimethylammoniophenyl)butyl)trimethyl-, diiodide is a bioactive chemical.

Substance P(1-4)为一有效的神经激肽受体(NK-R)拮抗剂，具有调节正常造血功能并抑制内源性红细胞集落(EEC)形成的能力。

3'',4''-Di-O-p-coumaroylquercitrin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5487，CAS号为 437615-43-5。

[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) 为高效的神经激肽 NK1 拮抗剂，能够有效抑制金蛋白 P 物质 (GPSP) 与 P 物质 (SP) 的活性。

Substance P (1-4) is a substance P N-terminal tetrapeptide fragment.

m-Anisidine, 4-((5-((p-chlorophenyl)thio)pentyl)oxy)- is a bioactive chemical.

Nucleoside Derivatives - 7-Deaza-8-aza-purine nucleosides; 6-Modified purine nucleosides

Glycolanilide, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

m-Toluidine, 4-(octyloxy)-alpha-(p-tolylsulfonyl)- is a bioactive chemical.

4-O-D-Glucopyranosyl-p-coumaric acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126288，CAS号为 117405-49-9。

m-Anisidine, 4-((p-(methylsulfonyl)benzyl)oxy)- is a bioactive chemical.

4''-O-trans-p-Coumaroylafzelin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6121，CAS号为 623927-14-0。

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin 在生命科学相关研究中具有广泛的应用。

4'-O-trans-p-Coumaroylmussaenoside是一种天然产物，属于马鞭草科紫珠属，其产品编号为 TN3065，CAS号为 1246012-27-0。4'-O-trans-p-Coumaroylmussaenoside可用作对照参考。