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Search Results for " hydrolase "
Targets Recommended: Epoxide Hydrolase NUDIX hydrolase Others

201

抑制剂 & 化合物

16

天然产物

96

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T40317 α/β-Hydrolase-IN-1

Others Others
α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M. smegmatis and 16 μM (8.4 μg/mL) against M. tuberculosis H37Ra, establishing it as a superior compound in this class.
T12974 Soluble epoxide hydrolase inhibitor

Others Others
Soluble epoxide hydrolase inhibitor is a soluble epoxide hydrolase inhibitor (human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4).
T83857 Soluble Epoxide Hydrolase PROTAC 1a

sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a

Others Others
Soluble epoxide hydrolase (sEH) PROTAC 1a是一种利用蛋白质降解靶向嵌合体(PROTAC)技术,通过连接区域将cereblon配体1与sEH抑制剂t-TUCB结合。该化合物通过促进sEH的降解,特异性抑制sEH的水解酶活性(IC50 = 0.8 nM),相较于其磷酸酶活性(IC50 = >10,000 nM)具有较高选择性。sEH PROTAC 1a还特定促进细胞质中而非过氧体中的sEH降解,并通过溶酶体而非蛋白酶体实现其降解。它能够降低thapsigargin诱导的HepG2与293T细胞中磷酸化的inositol-requiring enzyme 1α (IRE1α)水平和X-box结合蛋白1 (XBP1)剪接,表明能减少ER应激。
T75409 Nucleoside hydrolase (IAGNH)

Others Others
Nucleoside hydrolase (IAGNH)为一种糖苷酶,专门催化核苷中N-糖苷键的裂解,从而促进核碱基与Rib的循环利用。
T7898 AUDA

Epoxide Hydrolase Metabolism
AUDA 是可溶性环氧化物水解酶 (sEH) 抑制剂,在小鼠和人 sEH 的IC50分别为 18 和 69 nM,具有抗炎特性。
T78174 Serine Hydrolase inhibitor-21

Others Others
Serine Hydrolase inhibitor-21(化合物8)为一种抑制丝氨酸水解酶的吡啶类化合物,其对BuChE的Ki值为429 nM,有望用于阿尔茨海默病的研究。
T7199 TPPU

Epoxide Hydrolase Metabolism
TPPU 是一种可溶性环氧化物水解酶(sEH)抑制剂,对猴子和人类的IC50分别为37和3.7 nM。
T6043 PF-3845

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
PF3845 是一种有效的、选择性的和不可逆的脂肪酸酰胺水解酶(FAAH)抑制剂,Ki 为 230 nM。它是将 FAAH 的丝氨酸亲核试剂氨基甲酸酯化的共价抑制剂,可以减少疼痛感、炎症和焦虑或抑郁。
T14557 BI-1935

Epoxide Hydrolase Metabolism
BI-1935 是可溶性环氧化物水解酶抑制剂,用于与心血管疾病相关的疾病的研究。
T10900 CUDA

PPAR; Epoxide Hydrolase DNA Damage/DNA Repair; Metabolism
CUDA 是一种可溶性环氧水解酶抑制剂,对小鼠 sEH 和人 sEH 作用的 IC50分别为 11.1 和 112 nM。它能选择性地上调过氧化物酶体增殖激活受体 PPARα的活性,有用于心血管疾病的研究潜力。
T17158 trans-AUCB

t-AUCB

Epoxide Hydrolase Metabolism
trans-AUCB (t-AUCB) 是口服具有活力的、选择性的可溶性环氧水解酶 (sEH) 抑制剂,对人,小鼠和大鼠的 sEH 的IC50分别为 1.3 nM,8 nM,8 nM。它具有抗神经胶质瘤特性。
T14315 AR-9281

APAU

Epoxide Hydrolase Metabolism
AR-9281 (APAU) 是选择性的可溶性环氧化物水解酶抑制剂,可用于研究高血压和 2 型糖尿病。
T2684 JNJ-1661010

JNJ1661010,Takeda-25,JNJ 1661010

FAAH Metabolism; Neuroscience
JNJ-1661010 (Takeda-25) 是一种有效的、选择性的、可以穿透血脑屏障的脂肪酸酰胺水解酶 (FAAH) 抑制剂,对大鼠和人 FAAH 的 IC50分别为 34 和 33 nM,可用于缓解疼痛的研究。
T11147 EC5026

BPN-19186

Epoxide Hydrolase Metabolism
EC5026 (BPN-19186) 是首创的,非阿片类的,可溶性环氧水解酶 (sEH) 抑制剂,它可有效缓解发炎性和神经性疼痛。
T28353 PDP-EA

FAAH Metabolism; Neuroscience
PDP-EA 是脂肪酸酰胺水解酶 (FAAH) 的激活剂,可增强 FAAH 的酰胺水解酶活性。
T9967 MAGL-IN-5

Lipid Metabolism
MAGL-IN-5 是一种非选择性脂肪酶抑制剂。
T17196 UC-1728

t-TUCB

Epoxide Hydrolase Metabolism
UC-1728 (t-TUCB) 是一种兔子可溶性环氧化物水解酶抑制剂,兔子肝脏中测得其IC50=2 nM。
T9374 AA38-3

1-Piperidinecarboxylic acid, 4-nitrophenyl ester

FAAH; Lipase; MAGL Metabolism; Neuroscience
AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) 是丝氨酸水解酶抑制剂,能够抑制三种 SHs:ABHD6,ABHD11 和 FAAH。
T8844 Diflapolin

Others; FLAP; Epoxide Hydrolase Immunology/Inflammation; Metabolism; Others
Diflapolin 是高活性的双 5-脂氧合酶激活蛋白(FLAP)/可溶性环氧化物水解酶抑制剂,具有显著的抗炎作用和较高的靶向选择性。它抑制分离的 sEH 的活性,IC50为20 nM。它还抑制完整人单核细胞和中性粒细胞中 5-LOX 产物的形成,IC50分别为 30 和 170 nM。
T2338 JZL195

FAAH; Lipase; Autophagy Autophagy; Metabolism; Neuroscience
JZL195 是一种选择性有效的脂肪酸酰胺水解酶和单酰甘油脂肪酶双重抑制剂,IC50s 分别为 2 和 4 nM。
T3215 JNJ-42165279

JNJ42165279

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
JNJ-42165279 是一种 FAAH 抑制剂,抑制 hFAAH 和 rFAAH,IC50分别为70 ± 8 nM 和 313 ± 28 nM。它对其他酶、离子通道、转运蛋白和受体具有高度选择性。
T7688 4-Nonylphenylboronic acid

FAAH Metabolism; Neuroscience
4-Nonylphenylboronic acid 是 FAAH 的抑制剂。
T8927 WWL 154

WWL-154

FAAH Metabolism; Neuroscience
WWL 154 是一种丝氨酸水解酶 (SH) 和脂肪酸酰胺水解酶 FAAH-4 抑制剂。
T4323 PF-04457845

PF04457845,PF 04457845

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
PF-04457845 是一种非常有效的选择性 FAAH 抑制剂,作用于 rFAAH 和 hFAAH,IC50分别为 7.4±0.62 nM 和 7.2±0.63 nM。
T8646 URB937

FAAH Metabolism; Neuroscience
URB937 是一种口服具有活性的、外周限制的FAAH 抑制剂,IC50=26.8 nM,可增加 anandamide 水平,但不能影响脑内 FAAH 水平 (无法透过血脑屏障)。
T21859 ARM1

Aminopeptidase; Epoxide Hydrolase Metabolism
ARM1 是氨基肽酶和环氧化物水解酶抑制剂,IC50分别为为7.61 µM 和12.4 µM。
T15802 LY2183240

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
LY2183240 是大麻素摄取阻滞剂。它是内源性大麻素降解酶脂肪酸酰胺水解酶的有效共价抑制剂。它抑制脂肪酸酰胺水解酶 (FAAH) 活性,IC50 为12.4 nM。它也抑制其他几种脑丝氨酸水解酶,对 MAG 脂肪酶、bh6 和 KIAA1363 的 IC50分别为 5.3、0.09 和 8.2 nM。
T1325 Carprofen

卡洛芬,Ridamyl,Imadyl,Rimadyl

FAAH; COX; Autophagy Autophagy; Immunology/Inflammation; Metabolism; Neuroscience
Carprofen (Ridamyl) 是多靶点FAAH/COX 抑制剂,能够抑制 COX-2,COX-1 和 FAAH 的活性,IC50值分别为 3.9 μM,22.3 μM 和 78.6 μM。它是一种丙酸衍生物和非甾体抗炎药,具有抗炎、镇痛和解热活性。
T3354 BIA 10-2474

BIA10-2474

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
BIA 10-2474 是一种长效可逆的脂肪酸酰胺水解酶抑制剂,与人类内源性大麻素系统相互作用,可增加中枢神经系统和外周组织,对大鼠大脑不同区域的 IC50值为50至70mg/kg。它用于治疗焦虑症、帕金森氏病和多发性硬化症、高血压或肥胖症的慢性疼痛。
T15430 GSK2256294A

GSK 2256294

Others; Epoxide Hydrolase Metabolism; Others
GSK2256294A (GSK 2256294) 是重组人、大鼠和小鼠 sEH 的有效特异性抑制剂,IC50 分别为 27 pM、61 pM 和 189 pM。
T6697 TCID

UCH-L3 Inhibitor

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
TCID (UCH-L3 Inhibitor) 是一种有效的选择性神经元泛素 C 末端水解酶 L3 的 DUB 抑制剂,IC50为 0.6 μM。它对 L1 具有 125 倍的选择性,可减少脑干和脊髓原代神经元中的甘氨酸转运蛋白 GlyT2 泛素化。
T0355 Valpromide

Depamide,Valpramide,丙戊酰胺,Dipropylacetamide,2-propylpentanamide

Epoxide Hydrolase; HSV Metabolism; Microbiology/Virology
Valpromide (Dipropylacetamide) 是丙戊酸的羧酰胺衍生物,用于治疗癫痫和一些情感障碍。
T21696 SC-57461A

N -甲基- N -[3 - [4 - (苯甲基)苯氧基]丙基Β-丙氨酸盐酸盐

Aminopeptidase Metabolism
SC-57461A 是一种口服有活力的非肽类白三烯 A4 (LTA4) 水解酶选择性抑制剂,它能够抑制重组人 (IC50: 2.5 nM) 、小鼠 (IC50: 3 nM) 和小鼠LTA4水解酶 (IC50: 23 nM) 。
T11256 FAAH inhibitor 1

Benzothiazole analog 3

FAAH Metabolism; Neuroscience
FAAH inhibitor 1 (Benzothiazole analog 3) 是一种有效的脂肪酸酰胺水解酶抑制剂,IC50 为 18 nM。
T15268 FAAH-IN-2

O-Desmorpholinopropyl Gefitinib,4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) 是一种脂肪酸酰胺水解酶的有效抑制剂。
T8315 1-Cyclohexyl-3-dodecyl urea

CDU,N-Cyclohexyl-N-dodecyl urea,NCND

Epoxide Hydrolase Metabolism
1-Cyclohexyl-3-dodecyl urea (NCND) 是高选择性的可溶性环氧化物水解酶 (sEH) 抑制剂,能够增强血管紧张素 II (Ang II) 高血压中的环氧二十碳三烯酸 (EETs) 水平,并降低血压。
T6714 URB-597

KDS-4103,FAAH Inhibitor II

Mitophagy; FAAH; Autophagy Autophagy; Metabolism; Neuroscience
URB-597 (FAAH Inhibitor II) 是一种可口服的选择性FAAH 抑制剂。 它抑制大鼠脑膜、体外大鼠神经元和人肝微粒体中的 FAAH 活性,IC50分别为 5、0.5和 3 nM。它具有抗抑郁样作用,可研究缓解疼痛。
T23044 N,N'-Dicyclohexylurea

DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582,N,N-二环己脲

Epoxide Hydrolase Metabolism
N,N'-Dicyclohexylurea (AURORA KA-3582) 是一种可溶性环氧化物水解酶 (sEH) 抑制剂。
T13529 Acetylhydrolase-IN-1

Others Others
Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).
T10111 3-Deazaadenosine hydrochloride

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
3-Deazaadenosine hydrochloride 是 S-腺苷高半胱氨酸水解酶的抑制剂,Ki 值为 3.9 µM。 它具有抗炎、抗增殖和抗 HIV 活性。
T8994 ML-​226

ML226,ML-226

MAGL Metabolism
ML226 是 α/β hydrolase domain-containing protein 11 抑制剂,体外和原位的 IC50s 分别为 15 和 0.68 nM。
T22883 JW 480

Others Others
JW 480 是一种有效的丝氨酸水解酶 KIAA1363选择性抑制剂。
T2716 1,3-Diphenylurea

Epoxide Hydrolase Metabolism
1,3-Diphenylurea 与环氧化物水解酶活性有关。
T17260 WWL70

Lipase; MAGL Metabolism
WWL70 是选择性 α/β 水解酶结构域 6 抑制剂,其IC50=70 nM。
TQ0047 DG051

Aminopeptidase Metabolism
DG051 是有效的白三烯 A4 水解酶抑制剂,IC50=47 nM。
T63536 Dual FAAH/sEH-IN-1

FAAH; Epoxide Hydrolase Metabolism; Neuroscience
Dual FAAH/sEH-IN-1 是具有高度亲和力的sEH(可溶性环氧水解酶) (IC50: 9.6 nM) 和FAAH(脂肪酸酰胺水解酶) (IC50: 7 nM) 双重抑制剂,具有抗炎活性。
T15416 GR148672X

4,4,4-三氟-1-(2-噻吩基)-1,2,3-丁三酮 2-[(3-甲基苯基)腙]

Others Others
GR148672X 是三酰甘油水解酶抑制剂(IC50:4 nM)。
T15635 JZP-430

Lipase; MAGL Metabolism
JZP-430 是不可逆的、高度选择性的 α/β 水解酶结构域 6 抑制剂,能够靶向抑制人类 ABHD6 ,其 IC50=44 nM。
T23602 ABC99

ABC 99,ABC-99

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
ABC99是 wnt 脱酰基酶的一种选择性不可逆抑制剂。ABC99抑制 NOTUM(IC50:13 nM)。它还显示了对丝氨酸水解酶家族的优良选择性。
T3715 Acebilustat

阿西鲁司特,CTX-4430

Aminopeptidase; LTR Immunology/Inflammation; Metabolism
Acebilustat (CTX-4430) 是一种具有口服活性的白三烯 A4 水解酶抑制剂,可用于炎症研究。

化合物

α/β-Hydrolase-IN-1
Cat.No: T40317
Synonym:
Target: Others
Soluble epoxide hydrolase inhibitor
Cat.No: T12974
Synonym:
Target: Others
Soluble Epoxide Hydrolase PROTAC 1a
Cat.No: T83857
Synonym: sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a
Target: Others
Nucleoside hydrolase (IAGNH)
Cat.No: T75409
Synonym:
Target: Others
AUDA
Cat.No: T7898
Synonym:
Target: Epoxide Hydrolase
Serine Hydrolase inhibitor-21
Cat.No: T78174
Synonym:
Target: Others
TPPU
Cat.No: T7199
Synonym:
Target: Epoxide Hydrolase
PF-3845
Cat.No: T6043
Synonym:
Target: FAAH, Autophagy
BI-1935
Cat.No: T14557
Synonym:
Target: Epoxide Hydrolase
CUDA
Cat.No: T10900
Synonym:
Target: PPAR, Epoxide Hydrolase
trans-AUCB
Cat.No: T17158
Synonym: t-AUCB
Target: Epoxide Hydrolase
AR-9281
Cat.No: T14315
Synonym: APAU
Target: Epoxide Hydrolase
JNJ-1661010
Cat.No: T2684
Synonym: JNJ1661010,Takeda-25,JNJ 1661010
Target: FAAH
EC5026
Cat.No: T11147
Synonym: BPN-19186
Target: Epoxide Hydrolase
PDP-EA
Cat.No: T28353
Synonym:
Target: FAAH
MAGL-IN-5
Cat.No: T9967
Synonym:
Target: Lipid
UC-1728
Cat.No: T17196
Synonym: t-TUCB
Target: Epoxide Hydrolase
AA38-3
Cat.No: T9374
Synonym: 1-Piperidinecarboxylic acid, 4-nitrophenyl ester
Target: FAAH, Lipase, MAGL
Diflapolin
Cat.No: T8844
Synonym:
Target: Others, FLAP, Epoxide Hydrolase
JZL195
Cat.No: T2338
Synonym:
Target: FAAH, Lipase, Autophagy
JNJ-42165279
Cat.No: T3215
Synonym: JNJ42165279
Target: FAAH, Autophagy
4-Nonylphenylboronic acid
Cat.No: T7688
Synonym:
Target: FAAH
WWL 154
Cat.No: T8927
Synonym: WWL-154
Target: FAAH
PF-04457845
Cat.No: T4323
Synonym: PF04457845,PF 04457845
Target: FAAH, Autophagy
URB937
Cat.No: T8646
Synonym:
Target: FAAH
ARM1
Cat.No: T21859
Synonym:
Target: Aminopeptidase, Epoxide Hydrolase
LY2183240
Cat.No: T15802
Synonym:
Target: FAAH, Autophagy
Carprofen
Cat.No: T1325
Synonym: 卡洛芬,Ridamyl,Imadyl,Rimadyl
Target: FAAH, COX, Autophagy
BIA 10-2474
Cat.No: T3354
Synonym: BIA10-2474
Target: FAAH, Autophagy
GSK2256294A
Cat.No: T15430
Synonym: GSK 2256294
Target: Others, Epoxide Hydrolase
TCID
Cat.No: T6697
Synonym: UCH-L3 Inhibitor
Target: DUB
Valpromide
Cat.No: T0355
Synonym: Depamide,Valpramide,丙戊酰胺,Dipropylacetamide,2-propylpentanamide
Target: Epoxide Hydrolase, HSV
SC-57461A
Cat.No: T21696
Synonym: N -甲基- N -[3 - [4 - (苯甲基)苯氧基]丙基Β-丙氨酸盐酸盐
Target: Aminopeptidase
FAAH inhibitor 1
Cat.No: T11256
Synonym: Benzothiazole analog 3
Target: FAAH
FAAH-IN-2
Cat.No: T15268
Synonym: O-Desmorpholinopropyl Gefitinib,4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇
Target: FAAH, Autophagy
1-Cyclohexyl-3-dodecyl urea
Cat.No: T8315
Synonym: CDU,N-Cyclohexyl-N-dodecyl urea,NCND
Target: Epoxide Hydrolase
URB-597
Cat.No: T6714
Synonym: KDS-4103,FAAH Inhibitor II
Target: Mitophagy, FAAH, Autophagy
N,N'-Dicyclohexylurea
Cat.No: T23044
Synonym: DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582,N,N-二环己脲
Target: Epoxide Hydrolase
Acetylhydrolase-IN-1
Cat.No: T13529
Synonym:
Target: Others
3-Deazaadenosine hydrochloride
Cat.No: T10111
Synonym:
Target: Others, HIV Protease
ML-​226
Cat.No: T8994
Synonym: ML226,ML-226
Target: MAGL
JW 480
Cat.No: T22883
Synonym:
Target: Others
1,3-Diphenylurea
Cat.No: T2716
Synonym:
Target: Epoxide Hydrolase
WWL70
Cat.No: T17260
Synonym:
Target: Lipase, MAGL
DG051
Cat.No: TQ0047
Synonym:
Target: Aminopeptidase
Dual FAAH/sEH-IN-1
Cat.No: T63536
Synonym:
Target: FAAH, Epoxide Hydrolase
GR148672X
Cat.No: T15416
Synonym: 4,4,4-三氟-1-(2-噻吩基)-1,2,3-丁三酮 2-[(3-甲基苯基)腙]
Target: Others
JZP-430
Cat.No: T15635
Synonym:
Target: Lipase, MAGL
ABC99
Cat.No: T23602
Synonym: ABC 99,ABC-99
Target: Wnt/beta-catenin
Acebilustat
Cat.No: T3715
Synonym: 阿西鲁司特,CTX-4430
Target: Aminopeptidase, LTR
Cat. No. Product Name Target Signaling Pathways
TN6794 N-(3-methoxybenzyl)-octadecanamide

Others Others
N-(3-methoxybenzyl)-octadecanamide 从玛卡 (Lepidium meyenii Walp.) 转化而来。
T2859 Biochanin A

4-Methylgenistein,鹰嘴豆芽素A,Olmelin

EGFR; FAAH; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Biochanin A (4-Methylgenistein) 是一种从红三叶车轴草中分离出来的异黄酮衍生物,具有抗癌特性。它是脂肪酸酰胺水解酶抑制剂,作用于小鼠、大鼠和人 FAAH,IC50分别为 1.8、1.4 和 2.4 μM。
TN1965 N-​Benzyllinolenamide

N-苄基-(9Z,12Z,15Z)-十八碳三烯酰胺,N-Benzyllinolenamide

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
N-​Benzyllinolenamide 是从玛卡中得到的一种生物碱,是脂肪酰胺水解酶抑制剂,IC50 为 41.8 μM。
T12139 N-(3-Methoxybenzyl)Palmitamide

N-(3-甲氧基苄基)十六碳酰胺,玛卡酰胺杂质5

FAAH Metabolism; Neuroscience
N-(3-Methoxybenzyl)Palmitamide 是FAAH 抑制剂,可用于研究疼痛,炎症和中枢神经系统退行性疾病。
T3S2105 N-Benzylpalmitamide

Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide

Others; FAAH; Autophagy Autophagy; Metabolism; Neuroscience; Others
N-Benzylpalmitamide (Macamide 1) 是从玛卡中得到的一种生物碱,可以时间依赖性方式抑制脂肪酸酰胺水解酶,有治疗疼痛、炎症和中枢神经系统退行性疾病的研究潜力。
T4859 1-Monomyristin

rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate

Others; FAAH; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Metabolism; Microbiology/Virology; Neuroscience; Others
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) 是从 Serenoa repens 中提取的,抑制脂肪酸酰胺水解酶活性(IC50=18 μM) 和 2-油酰甘油的水解 (IC50=32 μM)。它对白色念珠菌有抗真菌活性,对金黄色葡萄球菌和聚集性放线菌有抗菌活性。
T19615 α-Amylase

Amylase Metabolism
α-Amylase 是一种能够催化淀粉中 α-1,4-糖苷键水解的水解酶,使淀粉产生葡萄糖、麦芽糖等产物。
T16075 (Rac)-Idroxioleic acid

2-Hydroxyoleic acid,2-OHOA,2-羟基乳清酸,Minerval

Apoptosis Apoptosis
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) 是一种具有抗肿瘤作用的脂肪酸酰胺水解酶抑制剂。 它与质膜结合并改变脂质组织。
T3529 Bestatin hydrochloride

盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素

Integrin; Aminopeptidase; Antibacterial; Antibiotic Cytoskeletal Signaling; Metabolism; Microbiology/Virology
Bestatin hydrochloride (Ubenimex hydrochloride) 是CD13(Aminopeptidase N)/APN 和leukotriene A4 hydrolase 抑制剂,可研究癌症。
T1257 Bestatin

Ubenimex,乌苯美司

Others; Aminopeptidase; Antibacterial; Antibiotic; LTR Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。
TN1761 Ikarisoside F

Others Others
Ikarisoside F and epimedin A can bind to AdoHcy hydrolase, inhibit the activity of AdoHcy hydrolase, thus regulating the cellular biomethylation as well as reducing cellular Hcy level.
T62258 Bestatin trifluoroacetate

Others Others
Bestatin trifluoroacetate (Ubenimex trifluoroacetate) 是一种 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,经常用于研究癌症。
TN7377 Methyl ganoderate A

Others Others
Methyl ganoderate A, an inhibitor of Farnesyl protein transferase (FPT) with an IC50 of 38 µM, exhibits potential anticancer effects. Additionally, it inhibits fatty acid amide hydrolase (FAAH), further underscoring its therapeutic potential.
T10369 Aristeromycin

U 99468

Antiviral Immunology/Inflammation
Aristeromycin (U 99468) 是一种靶向RNA病毒且具有广谱抗病毒作用的抗生素,是S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。
T37272 9(S),12(S),13(S)-TriHOME

Others Others
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
TN4592 Murrangatin

IL Receptor; TNF; COX; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line,

天然产物

N-(3-methoxybenzyl)-octadecanamide
Cat.No: TN6794
Synonym:
Target: Others
Biochanin A
Cat.No: T2859
Synonym: 4-Methylgenistein,鹰嘴豆芽素A,Olmelin
Target: EGFR, FAAH, Autophagy
N-​Benzyllinolenamide
Cat.No: TN1965
Synonym: N-苄基-(9Z,12Z,15Z)-十八碳三烯酰胺,N-Benzyllinolenamide
Target: FAAH, Autophagy
N-(3-Methoxybenzyl)Palmitamide
Cat.No: T12139
Synonym: N-(3-甲氧基苄基)十六碳酰胺,玛卡酰胺杂质5
Target: FAAH
N-Benzylpalmitamide
Cat.No: T3S2105
Synonym: Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide
Target: Others, FAAH, Autophagy
1-Monomyristin
Cat.No: T4859
Synonym: rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate
Target: Others, FAAH, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
α-Amylase
Cat.No: T19615
Synonym:
Target: Amylase
(Rac)-Idroxioleic acid
Cat.No: T16075
Synonym: 2-Hydroxyoleic acid,2-OHOA,2-羟基乳清酸,Minerval
Target: Apoptosis
Bestatin hydrochloride
Cat.No: T3529
Synonym: 盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素
Target: Integrin, Aminopeptidase, Antibacterial, Antibiotic
Bestatin
Cat.No: T1257
Synonym: Ubenimex,乌苯美司
Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR
Ikarisoside F
Cat.No: TN1761
Synonym:
Target: Others
Bestatin trifluoroacetate
Cat.No: T62258
Synonym:
Target: Others
Methyl ganoderate A
Cat.No: TN7377
Synonym:
Target: Others
Aristeromycin
Cat.No: T10369
Synonym: U 99468
Target: Antiviral
9(S),12(S),13(S)-TriHOME
Cat.No: T37272
Synonym:
Target: Others
Murrangatin
Cat.No: TN4592
Synonym:
Target: IL Receptor, TNF, COX, Prostaglandin Receptor
Cat. No. Product Name Species Expression System
TMPY-05055 GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)

GGH/Glutamyl hydrolase γ,γ-glutamyl hydrolase

Human HEK293 Cells
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.
TMPY-00877 Leukotriene A4 Hydrolase Protein, Human, Recombinant (His)

LAT4,leukotriene A4 hydrolase

Human Baculovirus Insect Cells
Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.7 kDa and the accession number is A0A140VK27.
TMPY-01658 Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His)

Lta4h,leukotriene A4 hydrolase

Mouse Baculovirus Insect Cells
Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.4 kDa and the accession number is P24527.
TMPH-02482 HIU hydrolase Protein, Mouse, Recombinant (His & Myc)

Transthyretin-related protein,5-hydroxyisourate hydrolas...

Mouse E. coli
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). HIU hydrolase Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.6 kDa and the accession number is Q9CRB3.
TMPY-00381 PSMA Protein, Human, Recombinant (His)

FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (pr...

Human HEK293 Cells
PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPH-01298 EPHX1 Protein, Human, Recombinant (His)

EPHX1,Microsomal epoxide hydrolase,Epoxide hydratas...

Human E. coli
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol.
TMPY-03330 BPHL Protein, Human, Recombinant (His)

biphenyl hydrolase-like (serine hydrolase)...

Human E. coli
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ...
TMPY-00583 ADPRH Protein, Human, Recombinant (His)

ADP-ribosylarginine hydrolase,ARH1

Human E. coli
Cholera toxin (CT) produced by Vibrio cholerae causes the devastating diarrhea of cholera by catalyzing the ADP-ribosylation of the alpha subunit of the intestinal Gs protein (Gsalpha), leading to characteristic water and electrolyte losses. Mammalian cells contain ADP-ribosyltransferases similar to CT and an ADP-ribosyl(arginine)protein hydrolase (ADPRH), which cleaves the ADP-ribose-(arginine)protein bond, regenerating native protein and completing an ADP-ribosylation cycle. CT-catalyzed ADP-r...
TMPH-03190 CPG2 Protein, Pseudomonas sp., Recombinant (GST)

Folate hydrolase G2,Pteroylmonoglutamic acid hy...

Pseudomonas E. coli
Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity. CPG2 Protein, Pseudomonas sp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.7 kDa and the accession number is P06621.
TMPH-00888 APEH Protein, Human, Recombinant (His)

Acylamino-acid-releasing enzyme,Acylaminoacyl-peptidase,Oxid...

Human E. coli
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. APEH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.2 kDa and the accession number is P13798.
TMPH-00760 Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His)

Cutin hydrolase,CUTA,Cutinase

Neocosmosporum cucurbitae P. pastoris (Yeast)
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection. Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 23.7 kDa and the accession number is Q99174.
TMPH-00761 Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant

Cutin hydrolase,CUTA,Cutinase

Neocosmosporum cucurbitae E. coli
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection. Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.4 kDa and the accession number is Q99174.
TMPH-00424 Cutinase Protein, Colletotrichum capsici, Recombinant (His & SUMO)

Cutinase,CUTA,Cutin hydrolase

Colletotrichum capsici E. coli
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection. Cutinase Protein, Colletotrichum capsici, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.0 kDa and the accession number is P10951.
TMPY-00410 EPHX2 Protein, Human, Recombinant (His)

SEH,CEH,epoxide hydrolase 2, cytoplasmic

Human Baculovirus Insect Cells
Genetic variation in EPHX2 was significantly associated with risk of incident CHD in Caucasians, implicating EPHX2 as a potential cardiovascular disease-susceptibility gene. Single nucleotide polymorphisms (SNPs) in the human EPHX2 gene had been implicated in susceptibility to cardiovascular disease, including stroke. The human EPHX2 mutations may in part explain the genetic variability in sensitivity to ischemic brain injury and stroke outcome. Epoxide hydrolase is involved in metabolism of vas...
TMPY-01865 BLMH Protein, Mouse, Recombinant (His)

Bh,bleomycin hydrolase,Bmh,AI035728

Mouse E. coli
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica...
TMPH-00657 NlpD Protein, E. coli, Recombinant (His & SUMO)

Murein hydrolase activator NlpD,nlpD

E. coli E. coli
Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division.
TMPH-01533 PPA1 Protein, Human, Recombinant (His)

Inorganic pyrophosphatase,PPA1,Pyrophosphate phospho-hyd...

Human E. coli
N/A. PPA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 10.8 kDa and the accession number is Q15181.
TMPY-01737 Meprin alpha/MEP1A Protein, Human, Recombinant (His)

meprin A, α (PABA peptide hydrolase),meprin A, alph...

Human HEK293 Cells
Meprin alpha/MEP1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.7 kDa and the accession number is Q16819.
TMPH-01511 GLO2 Protein, Human, Recombinant (GST)

Glyoxalase II,Hydroxyacylglutathione hydrolase, mit...

Human E. coli
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
TMPJ-00202 CD157 Protein, Human, Recombinant (hFc)

Cyclic ADP-ribose hydrolase 2,cADPr hydrolase

Human HEK293 Cells
The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth. CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities followed with CD38. It plays a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derive...
TMPH-00933 ADTRP Protein, Human, Recombinant (His & Myc)

Fatty acid esters of hydroxy fatty acids hydrolase ...

Human E. coli
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system.
TMPY-06325 USP14 Protein, Human, Recombinant (His)

USP14,Ubiquitin carboxyl-terminal hydrolase 14,TGT

Human E. coli
USP14 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 56.9 kDa and the accession number is NP_005142.1.
TMPH-00589 SpoT Protein, E. coli, Recombinant (His & Myc)

Bifunctional (p)ppGpp synthase/hydrolase SpoT,spoT

E. coli E. coli
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small ...
TMPH-01325 FAAH2 Protein, Human, Recombinant (His)

Amidase domain-containing protein,Anandamide amidohydrol...

Human E. coli
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. FAAH2 Protein, Human, Recombinant (His) is expressed in E. coli e...
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His)

HAGH1,GLO2,GLX2,hydroxyacylglutathione hydrolase,GL...

Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio...
TMPJ-00876 FAH Protein, Human, Recombinant (His)

Fumarylacetoacetate Hydrolase,β-Diketonase,FAH,FAA,...

Human HEK293 Cells
Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, ep...
TMPJ-00459 Esterase D Protein, Human, Recombinant (His)

FGH,Methylumbelliferyl-Acetate Deacetylase,ESD,S-Formylgluta...

Human E. coli
Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family. Esterase D is involved in the detoxification of formaldehyde. Esterase D plays a part in a variety of substrates, including O-acetylated sialic acids, which may involves in the recycling of sialic acids. Esterase D is used as a genetic marker for retinoblastoma and Wilson’s disease.
TMPH-00893 AHCY Protein, Human, Recombinant (His & SUMO)

AdoHcyase,S-adenosyl-L-homocysteine hydrolase,SAHH,...

Human E. coli
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. AHCY Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.6 kDa and the accession number is P23526.
TMPH-00673 NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)

NAD-capped RNA hydrolase NudC,nudC,NADH pyrophospha...

E. coli E. coli
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina...
TMPY-01318 Meprin alpha/MEP1A Protein, Mouse, Recombinant (His)

meprin A, alpha (PABA peptide hydrolase),AW107200,M...

Mouse HEK293 Cells
Meprin alpha/MEP1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is A0A0R4J043.
TMPH-01599 LCTL Protein, Human, Recombinant (His & Myc)

Lactase-like protein,Klotho/lactase-phlorizin hydrolase<...

Human E. coli
Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens. LCTL Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 67.2 kDa and the accession number is Q6UWM7.
TMPJ-01326 HDHD2 Protein, Human, Recombinant (His)

HDHD2,Haloacid Dehalogenase-Like Hydrolase Domain-C...

Human E. coli
Haloacid Dehalogenase-Like Hydrolase Domain-Containing Protein 22 (HDHD2) is a member of the HAD-like hydrolase superfamily. HDHD2 includes L-2-Haloacid Dehalogenase, Epoxide Hydrolases and Phosphatases. There are two active sites in HDHD2 - an L-2-Haloacid Dehalogenase and a Carboxylate group. The L-2-Haloacid Dehalogenase active site catalyzes the hydrolytic dehalogenation of D- and L-2-Haloalkanoic Acids, producing L- and D-2-Hydroxyalkanoic Acids.
TMPH-02866 RBBP9 Protein, Mouse, Recombinant (His)

Retinoblastoma-binding protein 9,Putative hydrolase...

Mouse P. pastoris (Yeast)
Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. RBBP9 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 22.4 kDa and t...
TMPY-01390 PSMA Protein, Mouse, Recombinant (His)

mopsm,folate hydrolase (prostate-specific membrane ...

Mouse HEK293 Cells
PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
TMPH-02549 FHIT Protein, Mouse, Recombinant (His)

Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferas...

Mouse E. coli
Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop...
TMPJ-00190 CD38 Protein, Mouse, Recombinant (hFc)

ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,T...

Mouse HEK293 Cells
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th...
TMPH-03323 LIPA Protein, Rat, Recombinant (His)

Lysosomal acid lipase/cholesteryl ester hydrolase,L...

Rat E. coli
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.6 kDa and the accession number is Q64194.
TMPH-02749 LCTL Protein, Mouse, Recombinant (His & Myc)

Lactase-like protein,Klotho/lactase-phlorizin hydrolase<...

Mouse E. coli
LCTL Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00907 MACROD1 Protein, Human, Recombinant (His)

MACROD1,Protein LRP16,O-acetyl-ADP-ribose deacetylase MACROD...

Human E. coli
MACROD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.5 kDa and the accession number is Q9BQ69.
TMPH-00908 MACROD1 Protein, Human, Recombinant (His & Myc)

ADP-ribose glycohydrolase MACROD1,MACROD1,[Protein ...

Human Baculovirus Insect Cells
MACROD1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-01929 ABHD18 Protein, Human, Recombinant (His & SUMO)

Abhydrolase domain-containing protein 18,Alpha/beta...

Human E. coli
ABHD18 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01626 LIPA Protein, Human, Recombinant (GST)

Lysosomal acid lipase/cholesteryl ester hydrolase,L...

Human E. coli
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.0 kDa and the accession number is P38571.
TMPY-03572 PTRH2 Protein, Human, Recombinant (His)

PTH 2,PTH2,peptidyl-tRNA hydrolase 2,CGI-147,CFAP37...

Human E. coli
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
TMPH-01740 SARM1 Protein, Human, Recombinant (His & Myc)

Tir-1 homolog,Sterile alpha and Armadillo repeat protein,Ste...

Human Baculovirus Insect Cells
SARM1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 80.4 kDa and the accession number is Q6SZW1.
TMPH-01625 LIPA Protein, Human, Recombinant (His)

Cholesteryl esterase,Lysosomal acid lipase/cholesteryl ester...

Human P. pastoris (Yeast)
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is P38571.
TMPH-01741 SARM1 Protein, Human, Recombinant (His & KSI)

Sterile alpha and Armadillo repeat protein,Sterile alpha mot...

Human E. coli
SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 48.8 kDa and the accession number is Q6SZW1.
TMPH-02283 USP18 Protein, Human, Recombinant (His)

ISG15-specific-processing protease,Ubl thioesterase 18,Ubl c...

Human E. coli
USP18 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 47.1 kDa and the accession number is Q9UMW8.
TMPH-02284 USP26 Protein, Human, Recombinant (His)

USP26,Deubiquitinating enzyme 26,Ubiquitin thioesterase 26,U...

Human E. coli
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
TMPH-01689 PLD6 Protein, Human, Recombinant (His)

Mitochondrial phospholipase,Choline phosphatase 6,Protein zu...

Human E. coli
Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the nuclease activity. Plays a key role in mitochondrial fusion and fission via its phospholipase activity. In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger sig...
TMPY-06960 PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

GCPII,FGCP,folate hydrolase (prostate-specific memb...

Human HEK293 Cells
PSMA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 82.72 kDa and the accession number is NP_004467.1.
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重组蛋白

GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)
Cat.No: TMPY-05055
Species: Human
Expression System: HEK293 Cells
Leukotriene A4 Hydrolase Protein, Human, Recombinant (His)
Cat.No: TMPY-00877
Species: Human
Expression System: Baculovirus Insect Cells
Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01658
Species: Mouse
Expression System: Baculovirus Insect Cells
HIU hydrolase Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02482
Species: Mouse
Expression System: E. coli
PSMA Protein, Human, Recombinant (His)
Cat.No: TMPY-00381
Species: Human
Expression System: HEK293 Cells
EPHX1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01298
Species: Human
Expression System: E. coli
BPHL Protein, Human, Recombinant (His)
Cat.No: TMPY-03330
Species: Human
Expression System: E. coli
ADPRH Protein, Human, Recombinant (His)
Cat.No: TMPY-00583
Species: Human
Expression System: E. coli
CPG2 Protein, Pseudomonas sp., Recombinant (GST)
Cat.No: TMPH-03190
Species: Pseudomonas
Expression System: E. coli
APEH Protein, Human, Recombinant (His)
Cat.No: TMPH-00888
Species: Human
Expression System: E. coli
Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant (His)
Cat.No: TMPH-00760
Species: Neocosmosporum cucurbitae
Expression System: P. pastoris (Yeast)
Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant
Cat.No: TMPH-00761
Species: Neocosmosporum cucurbitae
Expression System: E. coli
Cutinase Protein, Colletotrichum capsici, Recombinant (His & SUMO)
Cat.No: TMPH-00424
Species: Colletotrichum capsici
Expression System: E. coli
EPHX2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00410
Species: Human
Expression System: Baculovirus Insect Cells
BLMH Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01865
Species: Mouse
Expression System: E. coli
NlpD Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00657
Species: E. coli
Expression System: E. coli
PPA1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01533
Species: Human
Expression System: E. coli
Meprin alpha/MEP1A Protein, Human, Recombinant (His)
Cat.No: TMPY-01737
Species: Human
Expression System: HEK293 Cells
GLO2 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01511
Species: Human
Expression System: E. coli
CD157 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00202
Species: Human
Expression System: HEK293 Cells
ADTRP Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00933
Species: Human
Expression System: E. coli
USP14 Protein, Human, Recombinant (His)
Cat.No: TMPY-06325
Species: Human
Expression System: E. coli
SpoT Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00589
Species: E. coli
Expression System: E. coli
FAAH2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01325
Species: Human
Expression System: E. coli
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
Cat.No: TMPY-02288
Species: Human
Expression System: E. coli
FAH Protein, Human, Recombinant (His)
Cat.No: TMPJ-00876
Species: Human
Expression System: HEK293 Cells
Esterase D Protein, Human, Recombinant (His)
Cat.No: TMPJ-00459
Species: Human
Expression System: E. coli
AHCY Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00893
Species: Human
Expression System: E. coli
NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)
Cat.No: TMPH-00673
Species: E. coli
Expression System: E. coli
Meprin alpha/MEP1A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01318
Species: Mouse
Expression System: HEK293 Cells
LCTL Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01599
Species: Human
Expression System: E. coli
HDHD2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01326
Species: Human
Expression System: E. coli
RBBP9 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02866
Species: Mouse
Expression System: P. pastoris (Yeast)
PSMA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01390
Species: Mouse
Expression System: HEK293 Cells
FHIT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02549
Species: Mouse
Expression System: E. coli
CD38 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00190
Species: Mouse
Expression System: HEK293 Cells
LIPA Protein, Rat, Recombinant (His)
Cat.No: TMPH-03323
Species: Rat
Expression System: E. coli
LCTL Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02749
Species: Mouse
Expression System: E. coli
MACROD1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00907
Species: Human
Expression System: E. coli
MACROD1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00908
Species: Human
Expression System: Baculovirus Insect Cells
ABHD18 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01929
Species: Human
Expression System: E. coli
LIPA Protein, Human, Recombinant (GST)
Cat.No: TMPH-01626
Species: Human
Expression System: E. coli
PTRH2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03572
Species: Human
Expression System: E. coli
SARM1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01740
Species: Human
Expression System: Baculovirus Insect Cells
LIPA Protein, Human, Recombinant (His)
Cat.No: TMPH-01625
Species: Human
Expression System: P. pastoris (Yeast)
SARM1 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01741
Species: Human
Expression System: E. coli
USP18 Protein, Human, Recombinant (His)
Cat.No: TMPH-02283
Species: Human
Expression System: E. coli
USP26 Protein, Human, Recombinant (His)
Cat.No: TMPH-02284
Species: Human
Expression System: E. coli
PLD6 Protein, Human, Recombinant (His)
Cat.No: TMPH-01689
Species: Human
Expression System: E. coli
PSMA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06960
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...

同位素标记化合物

Orlistat-d3
Cat.No: T70882
Synonym:
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
TargetMol Loading
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