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TMPH-02027
|
RETNLB Protein, Human, Recombinant (His)
Colon carcinoma-related gene protein,Colon...
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Human
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E. coli
|
|
Probable hormone. RETNLB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is Q9BQ08. |
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TMPH-00856
|
RPSA Protein, Human, Recombinant (His & Myc)
67 kDa laminin receptor,RPSA,Laminin-binding protein precurs...
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Human
|
E. coli
|
|
RPSA Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.7 kDa and the accession number is P08865. |
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TMPJ-00662
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Receptor activator of nuclear factor kappa-B ligand,Receptor...
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Human
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E. coli
|
|
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog... |
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TMPY-01344
|
MAP1D Protein, Human, Recombinant (His)
MetAP 1D,Metap1l,MAP 1D,methionyl aminopeptidase type 1D (mi...
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Human
|
Baculovirus Insect Cells
|
|
Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D express... |
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TMPY-02249
|
FABP6 Protein, Human, Recombinant
I-BABP,I-BAP,ILLBP,I-15P,ILBP3,I-BALB,ILBP,fatty acid bindin...
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Human
|
E. coli
|
|
Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Isoform2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform1of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isof... |
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TMPJ-01195
|
BTNL9 Protein, Human, Recombinant (His)
BTNL9,Butyrophilin-like protein 9
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Human
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HEK293 Cells
|
|
Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Human BTNL9 mRNA has been identified in adipose, lung, thymus, spleen, colon, and cardiac tissues, but its highest levels of expression were found in B cells. BTNL9 expression has also been found to be down-regulated in colon cancer tumors. B... |
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TMPJ-01194
|
BTNL9 Protein, Human, Recombinant (hFc)
BTNL9,Butyrophilin-like protein 9
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Human
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HEK293 Cells
|
|
Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Human BTNL9 mRNA has been identified in adipose, lung, thymus, spleen, colon, and cardiac tissues, but its highest levels of expression were found in B cells. BTNL9 expression has also been found to be down-regulated in colon cancer tumors. B... |
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TMPK-01079
|
PLD4 Protein, Mouse, Recombinant (His)
Choline phosphatase 4,5'-3' exonuclease PLD4,Phospholipase D...
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Mouse
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HEK293 Cells
|
|
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cel... |
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TMPK-01138
|
PLD4 Protein, Human, Recombinant (His)
5'-3' exonuclease PLD4,PLD 4,Phospholipase D4,Choline phosph...
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Human
|
HEK293 Cells
|
|
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages. PLD4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel... |
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TMPH-02667
|
Galactosylceramidase Protein, Mouse, Recombinant
Galactocerebroside beta-galactosidase,Galactocerebrosidase,G...
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Mouse
|
E. coli
|
|
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. |
|
TMPJ-01209
|
BTNL9 Protein, Mouse, Recombinant (hFc)
BTNL9,Butyrophilin-like protein 9
|
Mouse
|
HEK293 Cells
|
|
Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Human BTNL9 mRNA has been identified in adipose, lung, thymus, spleen, colon, and cardiac tissues, but its highest levels of expression were found in B cells. BTNL9 expression has also been found to be down-regulated in colon cancer tumors. B... |
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TMPJ-00947
|
RPS19 Protein, Human, Recombinant
RPS19,40S Ribosomal Protein S19
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Human
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E. coli
|
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40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan... |
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TMPY-03521
|
DcR3 Protein, Human, Recombinant (hFc)
DCR3,tumor necrosis factor receptor superfamily member 6b,M6...
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Human
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Baculovirus Insect Cells
|
|
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tu... |
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TMPJ-00665
|
ADAMDEC1 Protein, Human, Recombinant (His)
a disintegrin and metalloproteinase domain-like protein decy...
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Human
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HEK293 Cells
|
|
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy. |
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TMPK-00435
|
SARS-COV-2 Spike S Trimer Protein (D614G, His & Avi)
S protein,Spike glycoprotein,COVID-19,S glycoprotein
|
SARS-CoV-2
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HEK293 Cells
|
|
The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Recently, that D614G was been found more infectious than the ancestral form on human lung cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs from various mammals, including Chinese rufous horseshoe bat and Malayan pangolin. |
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TMPY-04003
|
UNC5B Protein, Rat, Recombinant (hFc)
unc-5 homolog B (C. elegans)
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Rat
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HEK293 Cells
|
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The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular we... |
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TMPK-00743
|
LGR-5 Protein, Human, Recombinant (hFc)
G-protein coupled receptor HG38,G-protein coupled receptor 4...
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Human
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HEK293 Cells
|
|
G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma. |
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TMPJ-00799
|
ANXA2 Protein, Human, Recombinant
ANXA2,Calpactin I Heavy Chain,ANX2,p36,LPC2D,PAP-IV,ANX2L4,C...
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Human
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E. coli
|
|
Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell... |
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TMPH-01708
|
Mucin-2/MUC2 Protein, Human, Recombinant (His)
MUC2,Mucin-2,Intestinal mucin-2
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Human
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E. coli
|
|
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. Mucin-2/MUC2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.8 kDa an... |
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TMPU-00004
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STAT5A Protein, Human, Recombinant (His)
MGF,Signal transducer and activator of transcription 5A
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Human
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E. coli
|
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Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de... |
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TMPJ-00691
|
ZG16 Protein, Human, Recombinant (His)
Zymogen Granule Protein 16,ZG16,Zymogen Granule Membrane Pro...
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Human
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HEK293 Cells
|
|
Zymogen Granule Membrane Protein 16 (ZG16) belongs to the jacalin lectin family. ZG16 is highly expressed in liver and is detected at lower levels in colon, ileum and jejunum. ZG16 may play a role in protein trafficking. In addition, ZG16 may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. |
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TMPY-00507
|
UNC5B Protein, Human, Recombinant (hFc)
unc-5 homolog B (C. elegans),UNC5H2,p53RDL1
|
Human
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HEK293 Cells
|
|
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular ... |
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TMPY-04133
|
UNC5B Protein, Human, Recombinant (His)
UNC5H2,p53RDL1,unc-5 homolog B (C. elegans)
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Human
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HEK293 Cells
|
|
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular ... |
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TMPY-04058
|
RGS5 Protein, Human, Recombinant (His)
MST106,MSTP032,MST092,regulator of G-protein signaling 5,MST...
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Human
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E. coli
|
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RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins have recently been identified as signal transduction molecules which have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. The messenger RNA of hRGS5 was abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at l... |
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TMPJ-00687
|
B4GALT4 Protein, Human, Recombinant (His)
UDP-Gal:β-GlcNAc β-1,β4Gal-T4,4-Galactosyltransferase 4,UDP-...
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Human
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HEK293 Cells
|
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β-1,4-galactosyltransferase 4 (B4GALT4) is a single-pass type II membrane protein that belongs to the Glycosyltransferase 7 family. B4GALT4 consist of the following 2 domains: N-Acetyllactosamine Synthase and β-N-Acetylglucosaminyl-Glycolipid β-1,4-Galactosyltransferase. B4GALT4 is highly expressed in the heart, placenta, kidney, and pancreas; it is lowly expressed in the brain, colon, lung, muscle, ovary, testis, and uterus. B4GALT4 function is responsible for the synthesis of complex-type N-li... |
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TMPY-01771
|
Latexin Protein, Mouse, Recombinant (His)
latexin
|
Mouse
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E. coli
|
|
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional spe... |
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TMPY-03673
|
REG3B Protein, Mouse, Recombinant (His)
Pap,HIP,REG-III,PAP1
|
Mouse
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HEK293 Cells
|
|
Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis. |
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TMPJ-00974
|
XCL1 Protein, Human, Recombinant (hFc & His)
Cytokine SCM-1,Lymphotaxin,LTN,XC chemokine ligand 1,Small-i...
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Human
|
HEK293 Cells
|
|
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine calle... |
|
TMPY-04461
|
TRIB3 Protein, Human, Recombinant (GST)
SKIP3,C20orf97,tribbles pseudokinase 3,TRB3,SINK,NIPK
|
Human
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Baculovirus Insect Cells
|
|
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family and Tribbles subfamily. Highest expression Of TRIB3 is in liver, pancreas, peripheral blood leukocytes and bone marrow. It is also highly expressed in a number of primary lung, colon and breast tumors. TRIB3 is expressed in spleen, thymus, and prostate an... |
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TMPY-03285
|
PPIL1 Protein, Human, Recombinant (His)
CGI-124,PPIase,CYPL1,hCyPX,peptidylprolyl isomerase (cycloph...
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Human
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E. coli
|
|
PPIL1 is a member of the cyclophilin family. Cyclophilins are well conserved and ubiquitous. Members of cyclophilin family take a significant part in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL1 is a peptidylprolyl isomerase(PPIase). It increases the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIL1 is involved in proliferation of cancer cells through modulation of phosphorylation of... |
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TMPY-03867
|
CBR3 Protein, Human, Recombinant (His)
SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25
|
Human
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E. coli
|
|
CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo... |
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TMPJ-01288
|
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...
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Human
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E. coli
|
|
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... |
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TMPY-03601
|
PDRG1 Protein, Human, Recombinant (His)
PDRG,p53 and DNA-damage regulated 1,C20orf126
|
Human
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E. coli
|
|
PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissue... |
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TMPJ-00019
|
CCL28 Protein, Human, Recombinant
Small-Inducible Cytokine A28,Protein CCK1,CCL28,SCYA28,C-C M...
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Human
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E. coli
|
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Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expresse... |
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TMPJ-00859
|
AREG Protein, Human, Recombinant
AR,CRDGF,Amphiregulin,Colorectum Cell-Derived Growth Factor,...
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Human
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E. coli
|
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Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits... |
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TMPJ-01131
|
UBE2V2 Protein, Human, Recombinant (His)
Enterocyte Differentiation-Associated Factor 1,Vitamin D3-In...
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Human
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E. coli
|
|
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and... |
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TMPJ-00962
|
AKR1C3 Protein, Human, Recombinant (His)
3-Alpha-HSD Type 2,17-β-Hydroxysteroid Dehydrogenase Type 5,...
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Human
|
HEK293 Cells
|
|
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and ... |
|
TMPJ-00386
|
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...
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Human
|
HEK293 Cells
|
|
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate... |
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TMPJ-00055
|
Podoplanin Protein, Mouse, Recombinant (hFc)
T1-alpha,PA2.26 antigen,T1A,Podoplanin,T1-α,Glycoprotein 38,...
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Mouse
|
HEK293 Cells
|
|
Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. Detected at high levels in lung and brain, at lower levels in kidney, stomach, liver, spleen and esophagus, and not detected in skin and small intestine. Expressed in epithelial cells of choroid plexus, ependyma, glomerulus and ... |
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TMPJ-01293
|
SEMA3C Protein, Human, Recombinant (His)
Semaphorin-E,SEMA3C,SEMAE,Semaphorin-3C,Sema E
|
Human
|
HEK293 Cells
|
|
Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary ... |
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TMPJ-00349
|
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,O...
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Human
|
HEK293 Cells
|
|
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive... |
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TMPY-03172
|
Argininosuccinate lyase Protein, Human, Recombinant (His & GST)
ASAL,argininosuccinate lyase,ASL
|
Human
|
Baculovirus Insect Cells
|
|
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ... |
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TMPY-04307
|
GNRH2 Protein, Human, Recombinant (hFc)
LH-RHII,gonadotropin releasing hormone 2,GnRH-II,GNRH2
|
Human
|
HEK293 Cells
|
|
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleaved to form neuropeptides which, in part, regulate reproductive functions by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). 3 alternatively spliced human isoforms have been reported. The second mammalian... |
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TMPY-02223
|
GSTM2 Protein, Human, Recombinant (His)
GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (muscle),GSTM,...
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Human
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E. coli
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Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si... |
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TMPJ-00709
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LY6H Protein, Human, Recombinant (His)
Ly-6H,LY6H,Lymphocyte Antigen 6H
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Human
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HEK293 Cells
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Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precursor that contains a 25 amino acid signal sequence, 20 amino acid propeptide that is removed in the mature form, and a 90 amino acid mature chain. LY6H is highly expressed in the brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic ce... |
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TMPY-04899
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OGN/Osteoglycin Protein, Human, Recombinant (His)
OIF,OG,osteoglycin,SLRR3A
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Human
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HEK293 Cells
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OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epith... |
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TMPJ-00456
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APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
TRDL-1,TNFSF13,CD256,TALL-2,A proliferation-inducing ligand
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Mouse
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HEK293 Cells
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Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissu... |
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TMPY-03308
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ADAM17 Protein, Rat, Recombinant (His)
ADAM metallopeptidase domain 17
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Rat
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HEK293 Cells
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ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative colitis, a main form of inflammatory bowel disease. The expression of ADAM17 may be inhibited by ethanol. It is involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. ADAM1... |
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TMPJ-00320
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AMIGO2 Protein, Human, Recombinant (hFc)
DEGA,AMIGO-2,AMIGO2,ALI1,Alivin-1,Amphoterin-Induced Protein...
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Human
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HEK293 Cells
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Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2... |
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TMPY-02952
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SIAE Protein, Human, Recombinant (His)
CSE-C,AIS6,CSEC,LSE,YSG2,sialic acid acetylesterase
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Human
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Baculovirus Insect Cells
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Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the p... |
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