Azido-PEG2-t-butylester is a PEG derivative containing a t-butylester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.
FmocNH-PEG4-t-butylester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.
Hydroxy-PEG12-t-butylester is a PEG derivative containing a hydroxyl group and a t-butylester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carbox
Bromo-PEG2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Atorvastatin acetonide tert-butylester, a valuable pharmaceutical intermediate, is used in preparing Atorvastatin salts, an HMG-CoA reductase inhibitor.
t-Butyl acetate-PEG3-CH2COOH is a polyethylene glycol-derived PROteolysis TArgeting Chimera (PROTAC) linker, specifically designed for incorporation into the synthesis of PROTAC molecules.