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Search Results for " skeletal "
Targets Recommended: TRP/TRPV Channel

95

抑制剂 & 化合物

20

天然产物

2

化合物库

191

重组蛋白

5

同位素标记化合物

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Cat. No. Product Name
L1310 细胞骨架化合物库

759 compounds
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选;
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;

化合物库

细胞骨架化合物库
Cat.No: L1310
Compounds: 759
AMPK靶向分子库
Cat.No: L1120
Compounds: 80
Cat. No. Product Name Target Signaling Pathways
T23322 SB 452533

TRP/TRPV Channel Membrane transporter/Ion channel
SB 452533 是TRPV1的选择性拮抗剂,pKb 为 7.8。
T7144 BTS

N-Tosylbenzylamine,N-苄基-对甲苯磺酸胺,N-Benzyl-p-toluenesulfonamide

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
BTS (N-Tosylbenzylamine) 是一种选择性骨骼肌肌球蛋白 II 亚片段 1 (S1) ATPase 活性抑制剂,可特异性抑制骨骼肌快速纤维的收缩。它对肌动蛋白和 Ca2+刺激的肌球蛋白 S1 ATPase 的 IC50值约为 5 µM。
T0166 Pancuronium dibromide

Pancuronium bromide,Pavulon,泮库溴铵

AChR Neuroscience
Pancuronium dibromide (Pavulon) 是一种双季基类固醇,是一种神经肌肉松弛剂。它通过与乙酰胆碱竞争 nACh 受体上的结合位点来抑制神经肌肉传递。它还可抑制心脏毒蕈碱受体并具有拟交感神经作用。
T22967 MEDICA16

MEDICA 16

GPR; Others; ATP Citrate Lyase Endocrinology/Hormones; GPCR/G Protein; Metabolism; Others
MEDICA16 是 GPR40 的特异性激动剂以及 GPR120 的部分激动剂。 MEDICA16 是一种 ATP-柠檬酸裂解酶抑制剂,可显着降低腓肠肌中的细胞内 TG 含量,同时增加胰岛素敏感性。
T22371 Mivacurium dichloride

米库氯铵,Mivacurium chloride,二氯美维库铵

AChR Neuroscience
Mivacurium dichloride (Mivacurium chloride) 是苄基异喹啉衍生物,可与 nAChR 偶联,以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。它也是非去极化短效的神经肌肉阻滞剂和骨骼肌松弛剂。
T2176 2,3-Butanedione 2-Monoxime

Diacetyl monoxime,2,3-Butanedione-2-monoxime

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
2,3-Butanedione 2-Monoxime (Diacetyl monoxime) 是一种肌球蛋白 ATP 酶(myosin ATPase) 抑制剂。它诱导肌质网 Ca2+释放,能够有效抑制骨骼肌和心肌收缩。
T40101 (±)-1,2-Diolein

1,2-Dioleoyl-rac-glycerol,甘油1,2-二油酸酯

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) 是一种PKC 激活剂,可以增加肌小管 Ca2+内流。
T67965 Torbafylline

cAMP; PI3K; PDE GPCR/G Protein; Metabolism; PI3K/Akt/mTOR signaling
Torbafylline 是黄嘌呤衍生物,是 磷酸二酯酶 (PDE) 抑制剂,通过 激活 PDE4/cAMP/EPAC/PI3K/Akt 途径减弱烧伤诱导的大鼠骨骼肌蛋白水解,抑制癌症和败血症大鼠增强的骨骼肌泛素 - 蛋白酶体依赖性蛋白水解。
T64851 Phenprobamate

MH 532,Proformiphen,3-Phenylpropyl carbamate

Others Others
Phenprobamate (MH 532) 是一种作用于中枢骨骼肌的松弛剂,具有抗惊厥和稳定精神的作用。
T1459 Cisatracurium besylate

顺苯磺酸阿曲库铵,顺苯磺阿曲库铵,51W89

Adrenergic Receptor; AChR; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Cisatracurium besylate (51W89) 是一种用于静脉内给药的非去极化骨骼肌松弛剂。
T4054 Dantrolene sodium hemiheptahydrate

Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,丹曲林钠五水合物,Sodium dantrolene

Calcium Channel; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Dantrolene sodium hemiheptahydrate (Sodium dantrolene) 是一种钙通道蛋白抑制剂, 抑制钙离子从肌浆释放, 它是一种乙内酰脲衍生物和直接作用的骨骼肌松弛剂。
T25372 EMD57033

EMD-57033,(+)-EMD 57033,EMD 57033

Calcium Channel; Carbonic Anhydrase Membrane transporter/Ion channel; Metabolism
EMD57033是一种心脏肌钙蛋白C(cTnC)激活剂,是一种显性的Ca2+增敏剂。EMD57033通过与心脏/慢速骨骼肌钙蛋白C 异构体结合从而发挥促进心脏收缩的功能。
T67893 PTP1B-IN-22

Phosphatase Metabolism
PTP1B-IN-22是一种蛋白酪氨酸磷酸酶1B (PTP1B)抑制剂,可抑制骨骼肌 L6肌管的葡萄糖摄取。
T3966 Tirasemtiv

CK-2017357,泰拉生替

Others Others
Tirasemtiv (CK-2017357) 是一种快速骨骼肌型肌钙蛋白复合物激活剂。
T26287 Transcainide

R54718,R 54718,R-54718

Sodium Channel Membrane transporter/Ion channel
Transcainide(R 54718) 是一种新的利多卡因类似物,是具有口服活性的抗心律失常剂。Transcainide 可阻断牛心脏和大鼠骨骼肌中 BTX 激活的钠通道的开放状态。
T11805 L-NIL

NOS Immunology/Inflammation
L-NIL 是选择性一氧化氮合成酶 (iNOS) 抑制剂,可逆转大鼠骨骼肌中烧伤诱导的糖原合酶激酶-3β激活,可延缓鳞状细胞癌肺的进程。
T16728 Reldesemtiv

CK-2127107

Others Others
Reldesemtiv (CK-2127107) 是一种快速骨骼肌肌钙蛋白的选择性激活剂,EC50 为 3.4 μM。 Reldesemtiv 提高了心力衰竭模型中的运动表现。
T1889 CP-640186

CP 640186

Acetyl-CoA Carboxylase Metabolism
CP-640186 是一种有效的乙酰辅酶 A 羧化酶 (ACC)抑制剂,抑制大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50分别为 53 nM 和 61 nM。
T6618 Orphenadrine Citrate

Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君

AChR; iGluR Membrane transporter/Ion channel; Neuroscience
Orphenadrine Citrate (Flexon) 是NMDA 受体拮抗剂,Ki 为6.0μM,还是HERG 钾离子通道阻断剂。它是一种骨骼肌松弛剂,它作用于中枢神经系统以产生肌肉松弛作用。
T0156 Rocuronium bromide

ORG 9426,罗库溴铵,ORG 9426 (Bromide)

AChR Neuroscience
Rocuronium bromide (ORG 9426) 是一种氨基甾体类的、非去极化的神经肌肉受体抑制剂,也是一种肌肉松弛剂。
T77577 SLU-PP-332

Estrogen/progestogen Receptor Endocrinology/Hormones
SLU-PP-332 是一种泛雌激素受体相关受体 (ERR) 激动剂,其对 ERRα, ERRβ 以及 ERRγ 具有很高的亲和力,EC50 值分别为 98、230 以及 430 nM。SLUPP-332 可增强骨骼肌细胞系的线粒体功能和细胞呼吸,增加 IIa 型氧化骨骼肌纤维并增强了运动耐力。SLU-PP-332 具有研究代谢性疾病以及肌肉功能改善的潜力,可能用于改善代谢紊乱和衰老。
T24239 K201

K-201,JTV 519,JTV-519,K 201

Calcium Channel Membrane transporter/Ion channel; Metabolism
K201 (JTV-519) 是一种 Ca2+ 依赖性阻滞剂,通过稳定兰尼碱受体来防止缺血性心脏和骨骼肌 (SkM) 中的肌质网异常 Ca(2+) 泄漏。
T67951 JB061

Myosin Cytoskeletal Signaling
JB061是一种非肌肉肌球蛋白II抑制剂,针对心肌肌球蛋白、骨骼肌肌球蛋白和平滑肌肌球蛋白II的IC50分别为4.4 μM、9.1 μM和>100 μM。其对ATP酶活性的抑制作用较弱(IC50>200 μM)。此外,JB061对COS-7细胞显示出细胞毒性,IC50值为39 μM。
T77455 Burosumab

KRN23

Others Others
Burosumab(KRN23) 是一种靶向成纤维细胞生长因子 23 (FGF23) 的人单克隆抗体,用于治疗皮肤骨骼低磷血症综合征(CSHS)和肿瘤诱导的骨软化症。
T3622 CP-640186 hydrochloride

CP 640186 HCl,盐酸CP-640186

Acetyl-CoA Carboxylase Metabolism
CP-640186 hydrochloride (CP 640186 HCl) 是膜渗透性的乙酰辅酶A 羧化酶(ACC)抑制剂,抑制大鼠肝脏ACC1和大鼠骨骼肌ACC2的IC50为53 nM 和61 nM。
T67952 JB062

Myosin Cytoskeletal Signaling
JB062是一种针对非肌肉肌球蛋白(nonmusclemyosin)的抑制剂,其IC50值对骨骼肌肌球蛋白为1.6μM、心肌肌球蛋白为5.4μM,而对平滑肌肌球蛋白II大于100μM。此化合物对人类癌细胞显示出细胞毒性,对正常细胞则无此作用。JB062在肌肉痉挛、慢性肌肉骨骼疼痛及肥厚型心肌病研究中有潜在应用价值。
T21841 (±)-Hexanoylcarnitine chloride

DL-Hexanoylcarnitine chloride

Others; AChE Neuroscience; Others
(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物,能将脂肪酸分解成能够被身体利用的小分子化合物。(±)-Hexanoylcarnitine chloride 可通过大鼠骨骼肌毒性特异性从而作为一种生物标志物。(±)-Hexanoylcarnitine chloride 具有胆碱能活性。
T5005 Eperisone hydrochloride

Others Others
Eperisone Hydrochloride 是一种抗痉挛试剂,用于肌肉僵硬和疼痛为特征的疾病的相关研究。它是一种中枢作用的肌肉松弛剂,抑制疼痛反射通路,具有血管扩张作用。它通过放松骨骼肌和血管平滑肌来起作用,例如减少肌张力,改善循环和抑制疼痛反射。
T7535 RGX-202

胍基丙酸,β-GPA,3-Guanidinopropionic Acid

AMPK; PPAR Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling
RGX-202 (β-GPA) 是口服有活性的SLC6A8转运蛋白抑制剂。它在体内外均能够强烈地抑制肌酸输入,降低细胞内磷酸肌酸和 ATP 水平,诱导肿瘤凋亡,可于研究肿瘤。
T0077 Dantrolene sodium

Lapatinib ditosylate monohydrate,丹曲林钠,Dantrolene sodium salt

Others; Calcium Channel Membrane transporter/Ion channel; Metabolism; Others
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt 是一种骨骼肌松弛药,是一种钙通道蛋白抑制剂,可抑制钙离子从肌浆释放。
T12853 SBI-477

Others Others
SBI-477 是化学探针,能够使转录因子MondoA 失活,刺激胰岛素信号传导,使胰岛素途径抑制剂硫氧还蛋白相互作用蛋白和抑制蛋白结构域 4 的表达降低。它能够协调地抑制三酰基甘油酯合成,促进人骨骼肌细胞中的基础葡萄糖摄取。
T8773 MID-1

Others; IGF-1R Others; Tyrosine Kinase/Adaptors
MID-1 是 MG53-IRS-1 相互作用的抑制剂,能够破坏 MG53 与 IRS-1 的分子缔合,并消除 MG53 诱导的 IRS-1 泛素化和骨骼肌降解,升高 IRS-1 表达水平,增加胰岛素信号传导和葡萄糖摄取。
T7218 Endomorphin 2

内吗啡肽 2

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Endomorphin 2 是一种高亲和力和选择性的 μ-阿片受体激动剂,对 kappa3 结合位点具有合理的亲和力 ,Ki 为 20 到 30 nM 之间。
T22243 Anserine

L-鹅肌肽,L-Anserine

Endogenous Metabolite Metabolism
Anserine (L-Anserine) 是 Carnosine 的甲基化形式,是口服具有活性的天然二肽,存在于脊椎动物的骨骼肌。它不会被血清肌肽酶裂解,能够作为生化缓冲液,螯合剂,抗糖化剂和抗氧化剂。它能够改善阿尔茨海默氏病模型小鼠的记忆功能。
T6739 Zoledronic Acid

CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa

Apoptosis; Rho; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint
Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐,能抑制破骨细胞的分化和凋亡,具有高效的抗骨质再吸收活性,也有抗癌作用。
T3685 SR9009

Stenabolic,REV-ERB Agonist II

Autophagy Autophagy
SR9009 (Stenabolic) 是一种REV-ERBα/β激动剂,可增加由 REV-ERBα/ERBβ 调节的基因的组成性抑制,IC50分别为 670 nM 和 800 nM。
T22774L EEF1A1 (387-394) (Multiple species) (TFA)

Others Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物,负责将氨酰 tRNA 酶促递送至核糖体。这种亚型(α 1)在脑、胎盘、肺、肝、肾和胰腺中表达,另一种亚型(α 2)在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝,其中一些(如果不是全部)代表不同的假基因。
T6038 (-)-Blebbistatin

(S)-(-)-Blebbistatin

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
(-)-Blebbistatin ((S)-(-)-Blebbistatin) 是 blebbistatin 的 S 对映异构体。(-)-Blebbistatin 是一种肌球蛋白 II 抑制剂 (IC50=0.5-5 μM),具有有效性和选择性。(-)-Blebbistatin 可以用于抑制心肌肌球蛋白、非肌肉肌球蛋白II和骨骼肌肌球蛋白。
T29752 AHR-2666

AHR 2666

Others Others
AHR-2666 is a skeletal muscle relaxant.
T31783 Fenyripol hydrochloride

NSC 43183,NSC43183

Others Others
Fenyripol hydrochloride is a Relaxant of Skeletal Muscle.
T25637 Laudexium methylsulfate

Laudexium,Laudolissin methosulphate

Others Others
Laudexium methylsulfate is a neuromuscular blocking drug or skeletal muscle relaxant. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
T68366 Azumolene sodium dihydrate

Others Others
Azumolene sodium dihydrate is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor.
T29950L Ambenoxan hydrochloride

Ambenoxan HCl

Others Others
Ambenoxan hydrochloride is a centrally acting skeletal muscle relaxant.
T68882 Clodanolene sodium

Others Others
Clodanolene sodium is a skeletal muscle contraction antagonist.
T29846 Alcuronium free base

Alcuronium,Alcuronum,Diallylnortoxiferine,Alcuronium kation,Alloferine

Others Others
Alcuronium free base is a non-depolarizing skeletal muscle relaxant similar to Tubocurarine. It is used as an anesthesia adjuvant.
T24450 Mephenoxalone

Lenetran Lenetran,TAB Lenetranat

Others Others
Mephenoxalone is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission and relaxing skeletal muscles by inhibiting the reflex arc.
T25636 Laudexium

Laudexium ion,Laudexium cation

Others Others
Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle re
T71443 Amphidinolide D

Others Others
Amphidinolide D is a powerful activator of actomyosin ATPase enhances skeletal muscle contraction.
T69639 Sevasemten

Others Others
Sevasemten为骨骼肌肌球蛋白(Myosin)的变构抑制剂,具有选择性抑制作用,其IC50值对骨骼肌球蛋白 ≤ 10 μM,而对心脏肌球蛋白则 >100 μM。
T30321 Bentazepam

Tiadipone,CI-718,Knoll brand of bentazepam,Thiadipone

Others Others
Bentazepam is a thienodiazepine, which is a benzodiazepine analogue. It has anti-anxiety, anti-convulsion, sedative and skeletal muscle relaxation properties.

化合物

SB 452533
Cat.No: T23322
Synonym:
Target: TRP/TRPV Channel
BTS
Cat.No: T7144
Synonym: N-Tosylbenzylamine,N-苄基-对甲苯磺酸胺,N-Benzyl-p-toluenesulfonamide
Target: ATPase, Myosin
Pancuronium dibromide
Cat.No: T0166
Synonym: Pancuronium bromide,Pavulon,泮库溴铵
Target: AChR
MEDICA16
Cat.No: T22967
Synonym: MEDICA 16
Target: GPR, Others, ATP Citrate Lyase
Mivacurium dichloride
Cat.No: T22371
Synonym: 米库氯铵,Mivacurium chloride,二氯美维库铵
Target: AChR
2,3-Butanedione 2-Monoxime
Cat.No: T2176
Synonym: Diacetyl monoxime,2,3-Butanedione-2-monoxime
Target: Akt
(±)-1,2-Diolein
Cat.No: T40101
Synonym: 1,2-Dioleoyl-rac-glycerol,甘油1,2-二油酸酯
Target: PKC
Torbafylline
Cat.No: T67965
Synonym:
Target: cAMP, PI3K, PDE
Phenprobamate
Cat.No: T64851
Synonym: MH 532,Proformiphen,3-Phenylpropyl carbamate
Target: Others
Cisatracurium besylate
Cat.No: T1459
Synonym: 顺苯磺酸阿曲库铵,顺苯磺阿曲库铵,51W89
Target: Adrenergic Receptor, AChR, Autophagy
Dantrolene sodium hemiheptahydrate
Cat.No: T4054
Synonym: Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,丹曲林钠五水合物,Sodium dantrolene
Target: Calcium Channel, Autophagy
EMD57033
Cat.No: T25372
Synonym: EMD-57033,(+)-EMD 57033,EMD 57033
Target: Calcium Channel, Carbonic Anhydrase
PTP1B-IN-22
Cat.No: T67893
Synonym:
Target: Phosphatase
Tirasemtiv
Cat.No: T3966
Synonym: CK-2017357,泰拉生替
Target: Others
Transcainide
Cat.No: T26287
Synonym: R54718,R 54718,R-54718
Target: Sodium Channel
L-NIL
Cat.No: T11805
Synonym:
Target: NOS
Reldesemtiv
Cat.No: T16728
Synonym: CK-2127107
Target: Others
CP-640186
Cat.No: T1889
Synonym: CP 640186
Target: Acetyl-CoA Carboxylase
Orphenadrine Citrate
Cat.No: T6618
Synonym: Flexon,Flexoject,Banflex,枸酸芬那君,奥芬那君
Target: AChR, iGluR
Rocuronium bromide
Cat.No: T0156
Synonym: ORG 9426,罗库溴铵,ORG 9426 (Bromide)
Target: AChR
SLU-PP-332
Cat.No: T77577
Synonym:
Target: Estrogen/progestogen Receptor
K201
Cat.No: T24239
Synonym: K-201,JTV 519,JTV-519,K 201
Target: Calcium Channel
JB061
Cat.No: T67951
Synonym:
Target: Myosin
Burosumab
Cat.No: T77455
Synonym: KRN23
Target: Others
CP-640186 hydrochloride
Cat.No: T3622
Synonym: CP 640186 HCl,盐酸CP-640186
Target: Acetyl-CoA Carboxylase
JB062
Cat.No: T67952
Synonym:
Target: Myosin
(±)-Hexanoylcarnitine chloride
Cat.No: T21841
Synonym: DL-Hexanoylcarnitine chloride
Target: Others, AChE
Eperisone hydrochloride
Cat.No: T5005
Synonym:
Target: Others
RGX-202
Cat.No: T7535
Synonym: 胍基丙酸,β-GPA,3-Guanidinopropionic Acid
Target: AMPK, PPAR
Dantrolene sodium
Cat.No: T0077
Synonym: Lapatinib ditosylate monohydrate,丹曲林钠,Dantrolene sodium salt
Target: Others, Calcium Channel
SBI-477
Cat.No: T12853
Synonym:
Target: Others
MID-1
Cat.No: T8773
Synonym:
Target: Others, IGF-1R
Endomorphin 2
Cat.No: T7218
Synonym: 内吗啡肽 2
Target: Opioid Receptor
Anserine
Cat.No: T22243
Synonym: L-鹅肌肽,L-Anserine
Target: Endogenous Metabolite
Zoledronic Acid
Cat.No: T6739
Synonym: CGP-4244,CGP42446A,唑来膦酸,Zoledronate,CGP 42446,ZOL 446,Zometa
Target: Apoptosis, Rho, Autophagy
SR9009
Cat.No: T3685
Synonym: Stenabolic,REV-ERB Agonist II
Target: Autophagy
EEF1A1 (387-394) (Multiple species) (TFA)
Cat.No: T22774L
Synonym:
Target: Others
(-)-Blebbistatin
Cat.No: T6038
Synonym: (S)-(-)-Blebbistatin
Target: ATPase, Myosin
AHR-2666
Cat.No: T29752
Synonym: AHR 2666
Target: Others
Fenyripol hydrochloride
Cat.No: T31783
Synonym: NSC 43183,NSC43183
Target: Others
Laudexium methylsulfate
Cat.No: T25637
Synonym: Laudexium,Laudolissin methosulphate
Target: Others
Azumolene sodium dihydrate
Cat.No: T68366
Synonym:
Target: Others
Ambenoxan hydrochloride
Cat.No: T29950L
Synonym: Ambenoxan HCl
Target: Others
Clodanolene sodium
Cat.No: T68882
Synonym:
Target: Others
Alcuronium free base
Cat.No: T29846
Synonym: Alcuronium,Alcuronum,Diallylnortoxiferine,Alcuronium kation,Alloferine
Target: Others
Mephenoxalone
Cat.No: T24450
Synonym: Lenetran Lenetran,TAB Lenetranat
Target: Others
Laudexium
Cat.No: T25636
Synonym: Laudexium ion,Laudexium cation
Target: Others
Amphidinolide D
Cat.No: T71443
Synonym:
Target: Others
Sevasemten
Cat.No: T69639
Synonym:
Target: Others
Bentazepam
Cat.No: T30321
Synonym: Tiadipone,CI-718,Knoll brand of bentazepam,Thiadipone
Target: Others
Cat. No. Product Name Target Signaling Pathways
T8242 Sabinene

Others Others
Sabinene 是香料添加剂,具有成为下一代飞机燃料成分的成分。
T2S0820 Karanjin

干华豆晶 4,水黄皮素

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Karanjin 是干花豆中的主要活性呋喃黄酮醇成分,可通过细胞周期阻滞诱导癌细胞死亡,促进细胞凋亡,还通过提高AMPK 的方式诱导骨骼肌细胞 GLUT4 易位。
T4739 Sodium creatine phosphate dibasic tetrahydrate

磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate

Others; Endogenous Metabolite Metabolism; Others
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。
T7912 (−)-Myrtenal

(1R)-(-)-桃金娘烯醛,桃金娘烯醛,(1R)-(−)-Myrtenal

Others Others
(−)-Myrtenal 是一种具有口服活性及抗肿瘤活性的萜烯。(-)-Myrtenal 作用于糖尿病大鼠的骨骼肌和肝脏,利用 Akt 增强 GLUT2 ,进而改善高血糖症。
T4765 L-Norleucine

(S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid,L-2-氨基己酸

Influenza Virus; Endogenous Metabolite Metabolism; Microbiology/Virology
L-Norleucine ((S)-Norleucine) 是亮氨酸的异构体,特异性影响骨骼肌中的蛋白质合成,具有抗病毒活性。
T8771 Pongamol

Others Others
Pongamol 是一种从 Pongamia pinnata 果实中鉴定出的铅分子,对骨骼肌细胞的葡萄糖摄取和 GLUT4 易位。
T4333 Quinine dihydrochloride

盐酸奎宁,Quinine bimuriate

Others Others
Quinine dihydrochloride (Quinine bimuriate) 是Cinchona(Rubiaceae) 各种物种的主要生物碱。它也是一种抗疟药和肌肉松弛剂(骨骼)。
T4732 L-Carnosine

Karnozin,L-肌肽,beta-Alanyl-L-histidine

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
L-Carnosine (Karnozin) 是 由beta-丙氨酸和组氨酸组成的二肽,具有抑制衰老的作用。
T3262 Phosphocreatine disodium

Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠

Others; Endogenous Metabolite Metabolism; Others
Phosphocreatine disodium (Phosphocreatine disodium salt) 是一种磷酸化的肌酸分子,在肌肉、骨骼和大脑中作为一种可快速动员的高能磷酸盐储备。
T3S0195 Nootkatone

诺卡酮,努特卡酮,诺卡酮

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Nootkatone 是一种神经保护剂,来自于Alpiniae OxyphyllaeFructus ,具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。
T3232 Higenamine hydrochloride

Higenamine HCl,Demethylcoclaurine hydrochloride,盐酸去甲乌头碱,norcoclaurine HCl,(+-)-Demethylcoclaurine hydrochloride,Higenamine Hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Higenamine hydrochloride (norcoclaurine HCl) 是一种 β2-AR 激动剂,是用于心力衰竭相关研究的中药乌头的关键成分,具有抗凋亡活性。
T0266 Quinidine hydrochloride monohydrate

奎宁树,奎尼丁盐酸盐一水合物,奎尼丁盐酸盐,Quinidine hydrochloride

Potassium Channel; Sodium Channel; Parasite Membrane transporter/Ion channel; Microbiology/Virology
Quinidine hydrochloride monohydrate 是一种抗心律失常剂,也是 K+通道 (K+channel) 的有效阻断剂,其IC50值为 19.9 μM。它是一种有效且选择性的细胞色素 P450db (cytochrome P450db) 抑制剂,也可用作疟疾的研究。
T3403 Glabridin

光甘草定,Q-100692,KB-289522,LS-176045

Reactive Oxygen Species; Tyrosinase; GABA Receptor; Antibacterial; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
Glabridin (KB-289522) 能够结合并激活PPARγ,EC50值为 6115 nM,是一种从Glycyrrhiza glabra 中分到的异黄烷类天然产物。它具有抗炎、抗菌、抗肾炎、抗氧化、抗肿瘤、抗糖尿病、抗骨质疏松、保护神经、保护心血管、清除自由基等作用。
TN6945 Lactic acid

2-hydroxypropanoic acid

Others Others
Lactic acid (2-hydroxypropanoic acid) 是糖酵解的产物,广泛存在与自然界中。Lactate acid 在体内收缩骨骼肌缺氧时会产生,可在完全有氧条件下被去除。Lactic acid 可作为危重病人的血流动力学指标。Lactic acid 具有抗肿瘤活性。
T2O2733 L-Cystine

Cystine Acid,cystine,胱氨酸,L-胱氨酸

Antioxidant; Ferroptosis; Endogenous Metabolite Apoptosis; Metabolism; oxidation-reduction
L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用,保护组织免受辐射和污染,减缓衰老过程。它还有助于蛋白质合成。
T13265 Urolithin B

尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物,具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子,通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性,并抑制 JNK、ERK 和 Akt 的磷酸化,并增强 AMPK 的磷酸化。
T4883 Creatine

Methylguanidoacetic acid,肌酸

Endogenous Metabolite Metabolism
Creatine (Methylguanidoacetic acid) 是一种内源性氨基酸代谢物,在细胞能量中发挥重要作用,尤其是在肌肉和大脑中。
T19515 Phosphocreatine dipotassium

Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium)

Others Others
Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.
T20123 L-Carnitine hydrochloride

L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80

Others Others
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. Carnitine is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It has also been used to allow the en
TN3409 Anagyrine

Antifection Microbiology/Virology
Anagyrine, is the responsible teratogen from teratogenic lupins, can produce congenital deformities in calves typical of crooked calf disease; it also can induce red cell aplasia, vascular anomaly, and skeletal dysplasia.(-)-Anagyrine and (-)--Methylcytisine have nematicidal activities against Pine Wood Nematodes.

天然产物

Sabinene
Cat.No: T8242
Synonym:
Target: Others
Karanjin
Cat.No: T2S0820
Synonym: 干华豆晶 4,水黄皮素
Target: Apoptosis, AMPK
Sodium creatine phosphate dibasic tetrahydrate
Cat.No: T4739
Synonym: 磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate
Target: Others, Endogenous Metabolite
(−)-Myrtenal
Cat.No: T7912
Synonym: (1R)-(-)-桃金娘烯醛,桃金娘烯醛,(1R)-(−)-Myrtenal
Target: Others
L-Norleucine
Cat.No: T4765
Synonym: (S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid,L-2-氨基己酸
Target: Influenza Virus, Endogenous Metabolite
Pongamol
Cat.No: T8771
Synonym:
Target: Others
Quinine dihydrochloride
Cat.No: T4333
Synonym: 盐酸奎宁,Quinine bimuriate
Target: Others
L-Carnosine
Cat.No: T4732
Synonym: Karnozin,L-肌肽,beta-Alanyl-L-histidine
Target: Antioxidant, Endogenous Metabolite
Phosphocreatine disodium
Cat.No: T3262
Synonym: Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠
Target: Others, Endogenous Metabolite
Nootkatone
Cat.No: T3S0195
Synonym: 诺卡酮,努特卡酮,诺卡酮
Target: AMPK
Higenamine hydrochloride
Cat.No: T3232
Synonym: Higenamine HCl,Demethylcoclaurine hydrochloride,盐酸去甲乌头碱,norcoclaurine HCl,(+-)-Demethylcoclaurine hydrochloride,Higenamine Hydrochloride
Target: Adrenergic Receptor
Quinidine hydrochloride monohydrate
Cat.No: T0266
Synonym: 奎宁树,奎尼丁盐酸盐一水合物,奎尼丁盐酸盐,Quinidine hydrochloride
Target: Potassium Channel, Sodium Channel, Parasite
Glabridin
Cat.No: T3403
Synonym: 光甘草定,Q-100692,KB-289522,LS-176045
Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR
Lactic acid
Cat.No: TN6945
Synonym: 2-hydroxypropanoic acid
Target: Others
L-Cystine
Cat.No: T2O2733
Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸
Target: Antioxidant, Ferroptosis, Endogenous Metabolite
Urolithin B
Cat.No: T13265
Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮
Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK
Creatine
Cat.No: T4883
Synonym: Methylguanidoacetic acid,肌酸
Target: Endogenous Metabolite
Phosphocreatine dipotassium
Cat.No: T19515
Synonym: Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium)
Target: Others
L-Carnitine hydrochloride
Cat.No: T20123
Synonym: L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80
Target: Others
Anagyrine
Cat.No: TN3409
Synonym:
Target: Antifection
Cat. No. Product Name Species Expression System
TMPY-04414 MUSK Protein, Human, Recombinant (aa 433-783, His & GST)

FADS,CMS9,muscle, skeletal, receptor tyrosine kinas...

Human Baculovirus Insect Cells
Muscle, skeletal receptor tyrosine-protein kinase, also known as Muscle-specific tyrosine-protein kinase receptor, Muscle-specific kinase receptor, and MUSK, is a single-pass type I membrane protein that belongs to the protein kinase superfamily and tyr protein kinase family. MUSK contains one FZ (frizzled) domain, three Ig-like C2-type (immunoglobulin-like) domains, and one protein kinase domain. This protein is a muscle-specific tyrosine kinase receptor and it may play a role in clustering of ...
TMPH-00307 TnTf Protein, Bovine, Recombinant (His & Myc)

Tnnt3,Troponin T, fast skeletal muscle

Bovine E. coli
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TnTf Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.0 kDa and the accession number is Q8MKI3.
TMPH-00881 ACTA1 Protein, Human, Recombinant (His)

Actin, alpha skeletal muscle,Alpha-actin-1

Human E. coli
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 45.8 kDa and the accession number is P68133.
TMPY-03438 Calsequestrin 1 Protein, Human, Recombinant

CASQ,PDIB1,VMCQA,calsequestrin 1 (fast-twitch, skeletal<...

Human E. coli
Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. Two forms of calsequestrin have been identified: Calsequestrin-2 and Calsequestrin-1. Calsequestrin-1 is found in fast skeletal muscle. The release of calsequestrin-boun...
TMPH-02955 TNNI2 Protein, Mouse, Recombinant (His & Myc)

Tnni2,Troponin I, fast skeletal muscle,Troponin I, ...

Mouse E. coli
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P13412.
TMPH-02956 TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc)

Troponin I, slow skeletal muscle,Tnni1,Troponin I, ...

Mouse E. coli
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc) is expressed in E. coli expression system with N-10xHis-Flag and C-Myc tag. The predicted molecular weight is 29.6 kDa and the accession number is Q9WUZ5.
TMPH-01718 MUSK Protein, Human, Recombinant (His)

Muscle, skeletal receptor tyrosine-protein kinase,M...

Human P. pastoris (Yeast)
MUSK Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.8 kDa and the accession number is O15146.
TMPH-01731 MYBPC2 Protein, Human, Recombinant (His)

C-protein, skeletal muscle fast isoform,Myosin-bind...

Human E. coli
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. MYBPC2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.5 kDa and the accession number is Q14324.
TMPH-02790 MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)

Muscle-specific tyrosine-protein kinase receptor,Muscle,

Mouse E. coli
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-01353 FHL1 Protein, Human, Recombinant (His)

Skeletal muscle LIM-protein 1,FHL1,Four and a half ...

Human E. coli
May have an involvement in muscle development or hypertrophy. FHL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.3 kDa and the accession number is Q13642.
TMPH-00285 Myosin-1 Protein, Bovine, Recombinant (His & Myc)

Myosin heavy chain 2x,MYH1,Myosin heavy chain, skeletal<...

Bovine E. coli
Muscle contraction. Myosin-1 Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.9 kDa and the accession number is Q9BE40.
TMPH-02547 ENO3 Protein, Mouse, Recombinant (His & Myc)

Skeletal muscle enolase,Eno3,Enolase 3,2-phospho-D-...

Mouse E. coli
Appears to have a function in striated muscle development and regeneration. ENO3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.3 kDa and the accession number is P21550.
TMPH-02546 ENO3 Protein, Mouse, Recombinant (His)

Eno3,Beta-enolase,Skeletal muscle enolase,Muscle-sp...

Mouse P. pastoris (Yeast)
Appears to have a function in striated muscle development and regeneration.
TMPK-00687 keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)

KRT19,CK-19,K19,Keratin-19,CK19,Keratin19,Cytokeratin19,Cyto...

Canine E. coli
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker.
TMPK-00639 Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)

GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,ALPPL,ALPG,...

Rat HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293...
TMPH-00010 MMP-14 Protein, Human, Recombinant (His & SUMO)

Membrane-type-1 matrix metalloproteinase,MMP14,Membrane-type...

Human E. coli
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to...
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Receptor activator of nuclear factor kappa-B ligand,Receptor...

Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPY-05004 FGF-4 Protein, Human, Recombinant

HST-1,KFGF,fibroblast growth factor 4,HSTF1,K-FGF,HST,HBGF-4

Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His)

Nog,Noggin

Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPY-01085 VLDLR Protein, Human, Recombinant (His)

VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...

Human HEK293 Cells
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ...
TMPH-01415 GDF-8 Protein, Human, Recombinant (His)

Growth/differentiation factor 8,MSTN,Myostatin

Human E. coli
Acts specifically as a negative regulator of skeletal muscle growth. MSTN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.4 kDa and the accession number is O14793.
TMPK-00804 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc)

GCAP,Alkaline Phosphatase,PLAP-like,Alkaline phosphatase, pl...

Human HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) is expressed in HEK2...
TMPK-00803 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His)

ALPG,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho...

Human HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) is expressed in HEK2...
TMPK-00796 Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)

FLJ40094,ALPI,APTNAP,EC 3.1.3.1,AP-TNAP,IAP,TNAP,HOPS,FLJ930...

Human HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) is expr...
TMPK-01326 Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His)

Alkaline phosphatase,PLAP,PLAP-1,ALPP

Cynomolgus HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) is express...
TMPK-00801 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated

ALPPL2,PLAP-like,GCAP,ALPG,Alkaline phosphatase, placental-l...

Human HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ...
TMPK-00802 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc)

GCAP,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho...

Human HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) is expressed in HEK2...
TMPJ-00663 GDF-8 Protein, Human/Mouse/Rat, Recombinant

骨肉瘤源生长因子,Gdf8,Mstn,GDF-8,Growth/differentiation factor 8,Myo...

Human,Mouse,Rat HEK293 Cells
Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically a...
TMPK-00684 Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)

IAP,TNSALP,APTNAP,FLJ40094,AP-TNAP,MGC161443,TNAP,Akp2,HOPS,...

Mouse HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) is expressed i...
TMPK-00855 Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His)

Alkaline Phosphatase,Alppl2,Akp5,Alpg,Alkaline phosphatase, ...

Mouse HEK293 Cells
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) is expressed in HEK2...
TMPH-02651 Fbxo3 Protein, Mouse, Recombinant (His & Myc)

Muscle atrophy F-box protein,Atrogin-1,Fbxo32,F-box only pro...

Mouse E. coli
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
TMPH-02564 CARNMT1 Protein, Mouse, Recombinant (His & SUMO)

Carnosine N-methyltransferase,Carnmt1

Mouse E. coli
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
TMPH-00911 GPT Protein, Human, Recombinant (His)

Glutamic--alanine transaminase 1,Glutamate pyruvate transami...

Human E. coli
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. GPT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.5 kDa and the accession number is P24298.
TMPY-04126 MUSTN1 Protein, Human, Recombinant (His)

musculoskeletal, embryonic nuclear protein 1,MUSTAN...

Human E. coli
MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is localized to the nucleus in the myocardium and skeletal muscle fibers. It was expressed the greatest in skeletal muscle. The greatest relative growth rates appeared at the highest expression levels of the MUSTN1 gene, it was thought to play roles in duck muscle development. MUSTN...
TMPH-02629 ADAM12 Protein, Mouse, Recombinant (His & Myc)

Disintegrin and metalloproteinase domain-containing protein ...

Mouse Baculovirus Insect Cells
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.4 kDa and the accession number is Q61824.
TMPY-00569 B3GAT3 Protein, Human, Recombinant (His)

beta-1,3-glucuronyltransferase 3,glcUAT-I,GLCATI,β-1,3-glucu...

Human E. coli
B3GAT3, encoding beta-1,3-glucuronyltransferase 3, has an important role in proteoglycan biosynthesis. Homozygous B3GAT3 mutations have been associated with short stature, skeletal deformities, and congenital heart defects. There is a novel B3GAT3-related disorder with craniosynostosis and bone fragility, due to a unique homozygous mutation in B3GAT3.
TMPY-04934 Serpin A3n Protein, Rat, Recombinant (His)

serine (or cysteine) peptidase inhibitor, clade A, member 3N

Rat HEK293 Cells
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal muscle resident proteases during injury or dystrophic disease, which stabilizes the sarcolemma leading to less myofiber degeneration and increased regeneration.
TMPJ-01319 TINAGL1 Protein, Human, Recombinant (His)

LCN7,Tubulointerstitial nephritis antigen-like (TINAGL1),Oxi...

Human HEK293 Cells
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells.
TMPJ-00273 IGSF11 Protein, Human, Recombinant (hFc)

CXADRL1,BT-IgSF,CT119,Igsf13,VSIG3

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.IGSF11 functions as a cell adhesion molecule through homophilic interaction and can also stimulates cell growth.IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions.
TMPK-00695 N Cadherin Protein, Human, Recombinant (hFc)

CDHN,Neural cadherin,CDH2,N-cadherin,CDw325,CD325,NCAD

Human HEK293 Cells
Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
TMPK-00453 HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

p45-sErbB3,MDA-BF-1,ErbB-3,HER3c-erbB-3,ErbB3,MGC88033,LCCS2...

Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
TMPK-00452 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled

LCCS2,HER3c-erbB-3,p180-ErbB3,MGC88033,ErbB3,p85-sErbB3,p45-...

Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession numbe...
TMPK-01280 HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

p85-sErbB3,HER3,LCCS2,p180-ErbB3,HER3c-erbB-3,ErbB-3,ERBB3,M...

Cynomolgus,Rhesus HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number i...
TMPJ-01250 ATG4A Protein, Human, Recombinant (His)

ATG4A,Autophagin-2,AUT-Like 2 Cysteine Endopeptidase,APG4A,A...

Human E. coli
Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
TMPH-01751 Nephrin/NPHS1 Protein, Human, Recombinant (His)

Nephrin,Renal glomerulus-specific cell adhesion receptor,NPH...

Human E. coli
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Nephrin/NPHS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is O60500.
TMPJ-01193 CLM-9 Protein, Human, Recombinant (aa 19-247, His)

TREM4,Triggering Receptor Expressed on Myeloid Cells 4,CD300...

Human HEK293 Cells
CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG acts as a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG also binds SELL in a calcium dependent manner and lymphocyte. CD300LG may play a important role in molecular traffic across the capillary endothelium.
TMPJ-01298 PRADC1 Protein, Human, Recombinant (His)

Protease-associated domain-containing protein of 21 kDa,Prot...

Human HEK293 Cells
PRADC1, also known as C2orf7 or PAP21, is short for Protease-associated domain-containing protein 1. It is a 188 aa. with a 21 aa. signal, and the 171 located Asn can be glycosylated. PRADC1 has two mutagenesis which are N121Q and N171Q. This protein is secreted and highly expressed in skeletal muscle, heart and liver. It is expressed at intermediate level in kidney.
TMPY-03451 SPF30 Protein, Human, Recombinant (His)

SPF30,SMNR,TDRD16C,survival motor neuron domain containing 1

Human E. coli
SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. SMNDC1 gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. SMNDC1 is necessary for spliceosome assembly. Its overexpression causes apoptosis.
TMPJ-00462 NADK Protein, Human, Recombinant (His)

Poly(P)/ATP NAD Kinase,NADK,NAD Kinase

Human E. coli
NAD Kinase (NADK) is an enzyme that belongs to the NAD Kinase family. It is a widely expressed enzyme, but it is not detected in skeletal muscle. NADK converts Nicotinamide Adenine Dinucleotide (NAD+) into NADP+, through phosphorylating the NAD+ coenzyme. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. The structure of the NADK from the archaean Archaeoglobus fulgidus has been determined.
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重组蛋白

MUSK Protein, Human, Recombinant (aa 433-783, His & GST)
Cat.No: TMPY-04414
Species: Human
Expression System: Baculovirus Insect Cells
TnTf Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00307
Species: Bovine
Expression System: E. coli
ACTA1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00881
Species: Human
Expression System: E. coli
Calsequestrin 1 Protein, Human, Recombinant
Cat.No: TMPY-03438
Species: Human
Expression System: E. coli
TNNI2 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02955
Species: Mouse
Expression System: E. coli
TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc)
Cat.No: TMPH-02956
Species: Mouse
Expression System: E. coli
MUSK Protein, Human, Recombinant (His)
Cat.No: TMPH-01718
Species: Human
Expression System: P. pastoris (Yeast)
MYBPC2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01731
Species: Human
Expression System: E. coli
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02790
Species: Mouse
Expression System: E. coli
FHL1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01353
Species: Human
Expression System: E. coli
Myosin-1 Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00285
Species: Bovine
Expression System: E. coli
ENO3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02547
Species: Mouse
Expression System: E. coli
ENO3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02546
Species: Mouse
Expression System: P. pastoris (Yeast)
keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His)
Cat.No: TMPK-00687
Species: Canine
Expression System: E. coli
Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)
Cat.No: TMPK-00639
Species: Rat
Expression System: HEK293 Cells
MMP-14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00010
Species: Human
Expression System: E. coli
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Cat.No: TMPJ-00662
Species: Human
Expression System: E. coli
FGF-4 Protein, Human, Recombinant
Cat.No: TMPY-05004
Species: Human
Expression System: E. coli
BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
Noggin/NOG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
VLDLR Protein, Human, Recombinant (His)
Cat.No: TMPY-01085
Species: Human
Expression System: HEK293 Cells
GDF-8 Protein, Human, Recombinant (His)
Cat.No: TMPH-01415
Species: Human
Expression System: E. coli
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00804
Species: Human
Expression System: HEK293 Cells
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His)
Cat.No: TMPK-00803
Species: Human
Expression System: HEK293 Cells
Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00796
Species: Human
Expression System: HEK293 Cells
Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01326
Species: Cynomolgus
Expression System: HEK293 Cells
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00801
Species: Human
Expression System: HEK293 Cells
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00802
Species: Human
Expression System: HEK293 Cells
GDF-8 Protein, Human/Mouse/Rat, Recombinant
Cat.No: TMPJ-00663
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00684
Species: Mouse
Expression System: HEK293 Cells
Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00855
Species: Mouse
Expression System: HEK293 Cells
Fbxo3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02651
Species: Mouse
Expression System: E. coli
CARNMT1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02564
Species: Mouse
Expression System: E. coli
GPT Protein, Human, Recombinant (His)
Cat.No: TMPH-00911
Species: Human
Expression System: E. coli
MUSTN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04126
Species: Human
Expression System: E. coli
ADAM12 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02629
Species: Mouse
Expression System: Baculovirus Insect Cells
B3GAT3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00569
Species: Human
Expression System: E. coli
Serpin A3n Protein, Rat, Recombinant (His)
Cat.No: TMPY-04934
Species: Rat
Expression System: HEK293 Cells
TINAGL1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01319
Species: Human
Expression System: HEK293 Cells
IGSF11 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00273
Species: Human
Expression System: HEK293 Cells
N Cadherin Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00695
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00453
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00452
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-01280
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
ATG4A Protein, Human, Recombinant (His)
Cat.No: TMPJ-01250
Species: Human
Expression System: E. coli
Nephrin/NPHS1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01751
Species: Human
Expression System: E. coli
CLM-9 Protein, Human, Recombinant (aa 19-247, His)
Cat.No: TMPJ-01193
Species: Human
Expression System: HEK293 Cells
PRADC1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01298
Species: Human
Expression System: HEK293 Cells
SPF30 Protein, Human, Recombinant (His)
Cat.No: TMPY-03451
Species: Human
Expression System: E. coli
NADK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00462
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0164 L-Carnosine-d4

L-Carnosine-d4 是 L-Carnosine 的氘代化合物。L-Carnosine 的 CAS 号为 305-84-0。L-Carnosine 是 由beta-丙氨酸和组氨酸组成的二肽,具有抑制衰老的作用。
T36384 DL-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
T71285 Metaxalone-d6

Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ...
TMIJ-0494 Higenamine-d4 HCl

Higenamine-d4 HCl 是 Higenamine HCl 的氘代化合物。Higenamine HCl 的 CAS 号为 11041-94-4。Higenamine hydrochloride 是一种 β2-AR 激动剂,是用于心力衰竭相关研究的中药乌头的关键成分,具有抗凋亡活性。
TMID-0097 Ethyl-d5-malonic Acid

Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。

同位素标记化合物

L-Carnosine-d4
Cat.No: TMID-0164
Synonym:
Target:
DL-Tyrosine-13C9,15N
Cat.No: T36384
Synonym: L-Tyrosine-13C9,15N
Target:
Metaxalone-d6
Cat.No: T71285
Synonym:
Target:
Higenamine-d4 HCl
Cat.No: TMIJ-0494
Synonym:
Target:
Ethyl-d5-malonic Acid
Cat.No: TMID-0097
Synonym:
Target:
TargetMol Loading
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