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TMPY-04548
|
CDK4 Protein, Human, Recombinant (GST)
CMM3,PSK-J3,cyclin-dependent kinase 4
|
Human
|
Baculovirus Insect Cells
|
|
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of CDK4 is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). CDK4 was shown to be responsible for the phosphorylation of retinoblastoma gene product. CDK4 is the ser... |
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TMPH-03025
|
VlpE Protein, Mycoplasma hyorhinis, Recombinant (His & Myc)
VlpE prolipoprotein,Variant surface antigen E,vlpE
|
Mycoplasma hyorhinis
|
E. coli
|
|
Responsible for the antigenic diversity for host adaptation. Expression in E.coli of a construct containing vlpD, vlpE, and vlpF yields antigenically distinguishable products corresponding to each gene. |
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TMPH-00564
|
FabG Protein, E. coli, Recombinant (His & Myc)
Beta-Ketoacyl-acyl carrier protein reductase,fabG,Beta-ketoa...
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E. coli
|
E. coli
|
|
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. |
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TMPK-00236
|
CEACAM8 Protein, Human, Recombinant (His & Avi), Biotinylated
NCA-95,CD67,CGM6,CD66b,CEACAM8
|
Human
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HEK293 Cells
|
|
Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes. |
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TMPH-00665
|
RecG Protein, E. coli O157:H7, Recombinant (His & SUMO)
ATP-dependent DNA helicase RecG,recG
|
E. coli
|
E. coli
|
|
Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). Has a role in constitutive stable DNA replication (CsdR) and R-loop formation. |
|
TMPK-00479
|
AGER Protein, Cynomolgus, Recombinant (His)
AGER,RAGE,SCARJ1
|
Cynomolgus
|
HEK293 Cells
|
|
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer. |
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TMPJ-00586
|
SULT1A2 Protein, Human, Recombinant (His)
STP2,Aryl Sulfotransferase 2,ST1A2,Phenol Sulfotransferase 2...
|
Human
|
E. coli
|
|
Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cytoplasmic protein and exists as a homodimer. SULT1A2 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and might thus participate as a modulating factor of cancer risk. |
|
TMPH-00163
|
Levanase Protein, Bacillus sp., Recombinant (His & SUMO)
2,6-beta-D-fructan fructanohydrolase,Endo-levanase,Levanase
|
Bacillus
|
E. coli
|
|
Catalyzes the hydrolysis of levan with endo-type specificity. The products of levan hydrolysis are a mixture of fructose and a series of fructooligosaccharides up to 12-mer, with levantriose being the major oligosaccharide obtained. Is not active towards sucrose. Levanase Protein, Bacillus sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.3 kDa and the accession number is O31411. |
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TMPY-02120
|
XPNPEP2 Protein, Human, Recombinant (His)
AEACEI,X-prolyl aminopeptidase (aminopeptidase P) 2, membran...
|
Human
|
HEK293 Cells
|
|
Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution ... |
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TMPH-01843
|
Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N
|
HPIV-4b
|
E. coli
|
|
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 68.5 ... |
|
TMPJ-00892
|
TAC1 Protein, Human, Recombinant (His)
PPT,Protachykinin-1,TAC1
|
Human
|
E. coli
|
|
Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretag... |
|
TMPJ-00379
|
AOC3 Protein, Human, Recombinant (hFc)
SSAO,AOC3,Membrane primary amine oxidase,Copper amine oxidas...
|
Human
|
HEK293 Cells
|
|
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam... |
|
TMPY-02544
|
FANCA Protein, Human, Recombinant (His)
FA-H,FA1,FAA,FAH,FANCH,FACA,Fanconi anemia, complementation ...
|
Human
|
Baculovirus Insect Cells
|
|
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2. |
|
TMPJ-00860
|
HTN3 Protein, Human, Recombinant
HTN3,Histidine-rich protein 3,Histatin-3,Basic histidine-ric...
|
Human
|
E. coli
|
|
HTN3 belongs to the histatin/statherin family. Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Post-translational proteolytic processing results in many histatins: e.g., histatins 4-6 are derived from histatin 3 by proteolysis. Histatins 1 and 3 are primary products of HIS1and HIS2 alleles, respectively. Histatins are be... |
|
TMPH-00147
|
IBV (strain KB8523) Replicase polyprotein 1ab (His)
ORF1ab polyprotein,Replicase polyprotein 1ab,rep
|
IBV
|
Baculovirus Insect Cells
|
|
The replicase polyprotein of coronaviruses is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.; NendoU is a Mn(2+)-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond. IBV (strain KB8523) Replicase polyprotein 1ab (His) is expressed in Baculo... |
|
TMPH-01841
|
Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N
|
HPIV-1
|
E. coli
|
|
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. T... |
|
TMPH-03696
|
VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc)
Nucleocapsid protein,N,Nucleoprotein
|
VSIV
|
E. coli
|
|
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Nucleocapsid assembly is concommitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases. VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc) is expressed in E. coli expressi... |
|
TMPJ-00743
|
PPY Protein, Human, Recombinant (His)
Pancreatic prohormone,Pancreatic polypeptide,PNP,PPY
|
Human
|
HEK293 Cells
|
|
PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia n... |
|
TMPJ-01009
|
BLVRA Protein, Human, Recombinant (His)
Biliverdin reductase A,BVR,BVR A,BLVR,BLVRA,Biliverdin-IX α-...
|
Human
|
E. coli
|
|
Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ ... |
|
TMPJ-01428
|
SARS-CoV-2 NSP8 Protein (His)
SARS-CoV 2 nsp8
|
SARS-CoV-2
|
E. coli
|
|
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependen... |
|
TMPJ-00496
|
PGM2 Protein, Human, Recombinant (His)
Phosphopentomutase,Phosphodeoxyribomutase,Glucose phosphomut...
|
Human
|
E. coli
|
|
Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic reactions. When cells are grown in glucose, PGM catalyzes the conversion of glucose-6-phosphate to glucose-1-phosphate an important precursor required for the synthesis of UDP glucose and trehalose. PGM2 catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphope... |
|
TMPY-02453
|
CROT Protein, Human, Recombinant (474 Leu/Val, His)
carnitine O-octanoyltransferase,COT
|
Human
|
Baculovirus Insect Cells
|
|
Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate... |
|
TMPJ-00553
|
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(...
|
Human
|
HEK293 Cells
|
|
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen... |
|
TMPY-03659
|
GALE Protein, Human, Recombinant (His)
SDR1E1,UDP-galactose-4-epimerase
|
Human
|
E. coli
|
|
UDP galactose-4'-epimerase, also known as GALE, enables the body to process a simple sugar called galactose, which is present in small amounts in many foods. Galactose is primarily part of a larger sugar called lactose, which is found in all dairy products and many baby formulas. UDP galactose-4'-epimerase catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. Defects in GAL... |
|
TMPJ-00887
|
NFKB1 Protein, Human, Recombinant (His)
Nuclear factor of κ light polypeptide gene enhancer in B-cel...
|
Human
|
E. coli
|
|
The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory... |
|
TMPJ-00755
|
CRYAB Protein, Human, Recombinant (His)
α(B)-Crystallin,Alpha(B)-Crystallin,Heat Shock Protein Beta-...
|
Human
|
E. coli
|
|
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and or... |
|
TMPJ-00883
|
EGR1 Protein, Human, Recombinant (His)
zinc finger protein 225,NGFI-A,Zif268,Early growth response ...
|
Human
|
E. coli
|
|
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies su... |
|
TMPJ-01173
|
TFF3 Protein, Mouse, Recombinant (His)
Itf,Trefoil factor 3,Intestinal trefoil factor,mITF,Tff3
|
Mouse
|
HEK293 Cells
|
|
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process called restitution. TFF comprises the gastric peptides (TFF1), spasmolytic peptide (TFF2), and the intestinal trefoil factor (TFF3). They have an important and necessary role in epithelial restitution within the gastrointestinal tract. Members of the trefoil family are characterized b... |
|
TMPH-02212
|
TLR8 Protein, Human, Recombinant (His)
TLR8,Toll-like receptor 8
|
Human
|
P. pastoris (Yeast)
|
|
Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially processed by RNASET2. Recognizes GU-rich single-stranded RNA (GU-rich RNA) derived from SARS-CoV-2, SARS-CoV-1 and HIV-1 viruses. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-con... |
|
TMPJ-00292
|
CD36 Protein, Human, Recombinant (hFc)
FATCHDS7,Glycoprotein IIIb,SCARB3,CD36,Fatty acid translocas...
|
Human
|
HEK293 Cells
|
|
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition rece... |
|
TMPY-02516
|
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879,干扰...
|
Human
|
HEK293 Cells
|
|
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen... |
|
TMPY-00990
|
Lefty-A Protein, Human, Recombinant (hFc)
LEFTYA,left-right determination factor 2,LEFTA,TGFB4,EBAF
|
Human
|
HEK293 Cells
|
|
left-right determination factor 2 (Lefty2), also known as Left-right determination factor A (Lefty A), endometrial bleeding associated factor (left-right determination, factor A transforming growth factor-beta superfamily), and transforming growth factor beta-4, is a member of the TGF-beta family of proteins. This protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. Lefty2/Lefty A may also play a role in endometrial bleeding. Mutations i... |
|
TMPJ-00980
|
Complement Factor MASP3 Protein, Human, Recombinant (His)
PRSS5,CRARF,Serine Protease 5,MASP1,MASP-1,Mannose-Binding L...
|
Human
|
HEK293 Cells
|
|
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2... |
|
TMPY-02955
|
CABP5 Protein, Human, Recombinant (His)
calcium binding protein 5,CABP3
|
Human
|
E. coli
|
|
CABP3, also known as CABP5, belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of CABP3 gene is retina-specific. The mouse homolog of CABP3 has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of CABP3 gene is unknown. Study of the transcripts and genomic structure r... |
|
TMPY-04473
|
ADK Protein, Human, Recombinant (His & GST)
adenosine kinase,AK
|
Human
|
Baculovirus Insect Cells
|
|
Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons co... |
|
TMPY-02807
|
TWSG1 Protein, Mouse, Recombinant (His)
Twg,Twsg1,9030422N06Rik,AW552143,twisted gastrulation homolo...
|
Mouse
|
HEK293 Cells
|
|
TWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone ... |
|
TMPY-01290
|
CHIT1 Protein, Human, Recombinant (His)
chitinase 1 (chitotriosidase),CHITD,CHI3,CHIT
|
Human
|
HEK293 Cells
|
|
Chitotriosidase, also known as Chitinase-1 and CHIT1, is a member of the glycosyl hydrolase 18 family and Chitinase class II subfamily. It is a member of the mammalian chitinase family, structurally homologous to chitinases from other species, is synthesized and secreted by specifically activated macrophages. Chitotriosidase is a polymer of N-acetylglucosamine. Serum and plasma chitotriosidase activity is usually measured as the first step in diagnosis of Gaucher disease. Monitoring chitotriosid... |
|
TMPH-01532
|
IKBKB Protein, Human, Recombinant (E. coli, His)
Nuclear factor NF-kappa-B inhibitor kinase beta,Serine/threo...
|
Human
|
E. coli
|
|
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu... |
|
TMPY-02299
|
ALDH3A1 Protein, Human, Recombinant (His)
ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3
|
Human
|
Baculovirus Insect Cells
|
|
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi... |
|
TMPH-01531
|
IKBKB Protein, Human, Recombinant (His)
Serine/threonine protein kinase IKBKB,Nuclear factor NF-kapp...
|
Human
|
Baculovirus Insect Cells
|
|
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu... |
|
TMPY-01709
|
HIF-1 alpha Protein, Human, Recombinant (His)
bHLHe78,HIF-1 α,hypoxia inducible factor 1, alpha subunit (b...
|
Human
|
E. coli
|
|
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has... |
|
TMPY-04542
|
CDK2 Protein, Human, Recombinant (His)
CDKN2,cyclin-dependent kinase 2,p33(CDK2)
|
Human
|
Baculovirus Insect Cells
|
|
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. Cdks (cyclin-dependent kinases) are heteromeric serine/threonine kinases that control progression through the cell cycle in concert with their regulatory subunits, the c... |
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