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Targets Recommended: Others

106

抑制剂 & 化合物

11

天然产物

1

化合物库

15

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name
L2900 氧化还原化合物库

1264 compounds
1264 个活性化合物,已经验证具有一定的抗氧化活性,包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物,是研究疾病机理以及药物研究的优良载体

化合物库

氧化还原化合物库
Cat.No: L2900
Compounds: 1264
Cat. No. Product Name Target Signaling Pathways
T11064 DMT1 blocker 2

Others Others
DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。
T20984 Lumogallion

荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid

Others Others
Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) 是一种偶氮试剂,用于测定金属离子,如研究 V、Fe 和 Al。
T39477 Ca-DTPA trisodium salt hydrate

Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

Others Others
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 是螯合剂和有用的解毒剂,如急性镉中毒。它是一种无毒的 CMV 复制抑制剂。
T0420 Pentetic Acid

Acidum penteticum,Detarex,二乙烯三胺五醋酸,Detapac,DTPA,diethylenetriaminepentaacetic acid

Others Others
Pentetic Acid (Detarex) 是一种能够构建磁性吸附剂的化合物,能够去除复杂废水中的重金属及染料。
T2096 Framycetin sulfate

Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate

Antibacterial; Antibiotic Microbiology/Virology
Framycetin sulfate (Neomycin Sulphate B) 是一种氨基糖苷类抗生素,是 RNase P 裂解活性抑制剂,Ki 为 35 μM。它抑制锤头状核酶,Ki 值为 13.5 μM,可用于肝性脑病和肠致病性大肠杆菌感染的研究。
T38476 Metallo β-lactamase ligand 1

Antibacterial Microbiology/Virology
Metallo β-lactamase ligand 1 是B 类β-内酰胺酶的抑制剂,具有抗菌活性。
T60694 Metallo-β-lactamase-IN-4

Others Others
Metallo-β-lactamase-IN-4 (compound 40) 是金属 -β- 内酰胺酶 (MBL) 的有效抑制剂,对VIM-1、NDM-1 和 IMP 的IC50值分别为 0.5 μM, 2.1 μM 和 3.3 μM。
T60914 Metallo-β-lactamase-IN-8

Others Others
Metallo-β-lactamase-IN-8 (化合物 17) 是有效,可逆和竞争性的广谱金属-β-内酰胺酶 (MβLs)抑制剂,具有抗菌活性。Metallo-β-lactamase-IN-8 对L1,ImiS,IMP-1和VIM-2的IC50值分别为 1.3 μM,5.7 μM,9.8 μM。
T20066 Metalaxyl

Ridomil 72WP,Allegiance,CGA48988,CGA-48988,CGA 48988,Metalaxil

Others Others
Metalaxyl is an acylalanine fungicide with systemic function. It can be used to control Pythium in a number of vegetable crops, and Phytophthora in peas.
T40816 Metalaxyl-M

Metalaxyl-M,(R)-Metalaxyl

Others Others
Metalaxyl-M ((R)-Metalaxyl), the active (R)-enantiomer of Metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal RNA synthesis in fungi. It is employed in the research of plant diseases attributed to pathogens from the Oomycota division.
T60370 Metallo-β-lactamase-IN-2

Others Others
Metallo-β-lactamase-IN-4 (compound 40) 是一种有效的金属 -β- 内酰胺酶 (MBL) 抑制剂,其对于 VIM-1、NDM-1和 IMP-7的 IC50值分别为 0.1 μM, 1.3 μM 和 5.0 μM。
T61173 Metallo-β-lactamase-IN-5

Others Others
Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactamase-IN-5 effectively inhibits HUVECs. Additionally, when combined with Imipenem, Metallo-β-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
T60494 Metallo-β-lactamase-IN-7

Others Others
Metallo-β-lactamase-IN-7 是VIM 型金属 β-内酰胺酶的有效抑制剂,其对VIM-2、VIM-1和VIM-5 的IC50值分别为 0.019 μM、13.64 μM 和 0.38 μM。它还可以增强 Meropenem 对革兰氏阴性菌的抗菌活性。
T72261 Metallo-β-lactamase-IN-9

Others Others
Metallo-β-lactamase-IN-9 (Compound 23) 是一种高效的泛金属-β-内酰胺酶 (MBL) 抑制剂,其对 NDM-1、VIM-1 和 IMP-1 的抑制活性表现在 IC50 值上,分别为 35 nM、269 nM 和 369 nM。
T60282 Metallo-β-lactamase-IN-3

Others Others
Metallo-β-lactamase-IN-3 (compound 35) 是一种有效的金属 -β- 内酰胺酶 (MBL) 抑制剂,具有恢复现有 β-内酰胺类抗生素活性的潜力并为新抗生素的发现提供正交策略。Metallo-β-lactamase-IN-3 对 VIM-1和 NDM-1的活性较高,其 IC50值分别为 0.6 和 1.0 μM。Metallo-β-lactamase-IN-3 对 IMP-7 无抑制作用。
T60239 Metallo-β-lactamase-IN-6

Others Others
Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lactamase-IN-6 exhibits potent synergistic antibacterial properties when combined with Meropenem, particularly against engineered Escherichia coli strains and clinically isolated Pseudomonas aeruginosa carrying the VIM-2 MBL gene [1].
T79435 Metallo-β-lactamase-IN-11

Others Others
Metallo-β-lactamase-IN-11(化合物5f)是一种针对Metallo-β-lactamases(MBLs)的抑制剂,对CphA表现出较强的抑制活性(IC50=45 µM)。在10 µM浓度下,能分别抑制49%的NDM-1和61%的AIM-1。此化合物对于研究针对抗生素耐药性的策略具有潜在应用价值。
T31479 Diisopropyl xanthogen disulfide

NSC1339,NSC 1339,Isopropylxanthic disulfide,二硫化二异丙基黄原酸酯,NSC-1339

Others Others
Diisopropyl xanthogen disulfide (NSC-1339) 可用于合成与钼辅因子相关的金属络合物的前配体。
T20736 Cryptating agent 222

Cryptate 222,NSC 264495,NSC-264495,NSC264495

Others Others
Cryptating agent 222 (NSC-264495) 是穴状配体,与钾镜一起使用以将受阻二锡烯还原为结晶自由基阴离子并与金属阳离子形成配体。
T73718 MDCG sodium

NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium

Endogenous Metabolite Metabolism
MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) 是一种金属螯合剂,可促进Cd的胆道排泄。
T65167 EDTA copper(II) disodium salt

Antibiotic Microbiology/Virology
EDTA copper(II) disodium salt 是一种金属螯合剂,具有抗菌、抗炎、抗氧化活性,可减缓金属离子造成的损伤,可维持蛋白纯化过程中的渗透压,可用于研究神经系统疾病。
T20841 Nitrilotriacetic acid

Triglycollamic acid,Nitrilotriacetate,Nitriloacetate

Others Others
Nitrilotriacetic acid (Nitriloacetate) 是一种螯合剂,可与二价金属离子介导的6His标签反应来跟踪和富集活细胞中的His标签蛋白。
T11063 DMT1 blocker 1

Others Others
DMT1 blocker 1 是二价金属转运蛋白1 (DMT1) 的阻断剂,IC50 为 0.64 μM,可以阻断体内肠细胞的铁摄取。
T22402 Potassium thioacetate

Others Others
Potassium thioacetate 它已被用于合成聚合物、杂环、纳米颗粒、过渡金属配体、生物活性化合物和大分子包合物。
T0423 Ethylenediaminetetraacetic acid trisodium salt

乙二胺四乙酸三钠,Edetate Trisodium,ethylenediaminetetraacetic acid Trisodium,EDTA Trisodium,Trisodium EDTA,依地酸三钠盐,Edetate Trisodium,EDTA trisodium salt

Others; Ferroptosis Apoptosis; Others
Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) 在螯合疗法中用于结合金属离子。它还用于汞和铅中毒的研究,也可除去体内多余的铁,用于研究地中海贫血。
T9241 o-Cresolphthalein Complexone

Others Others
o-Cresolphthalein Complexone 是一种金属络合指示剂和酸碱指示剂。
T19936 Xantphos

Others Others
Xantphos 是 Buchwald, Suzuki 等偶联反应中的配体,是可用于催化反应的金属螯合配体。
T3952 TPEN

TPEDA

Apoptosis; Reactive Oxygen Species; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB
TPEN (TPEDA) 是一种特定的细胞可渗透的重金属螯合剂,对 Zn2+具有高亲和力,但对 Mg2+和 Ca2+具有较低的亲和力。它诱导 DNA 损伤并增加细胞内ROS 的产生,还抑制细胞增殖并诱导凋亡。
T15213 Emeramide

BDTH2,N,N'-二(2-巯基乙基)间苯二甲酰胺

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Emeramide (BDTH2) 是一种硫醇氧化还原抗氧化剂,也是一种重金属螯合剂。
T8813 Tetrakis (4-carboxyphenyl) porphyrin

中-四(4-羧基苯基)卟吩,TCPP,Tetracarboxyphenylporphine

Others Others
Tetrakis (4-carboxyphenyl) porphyrin (TCPP) 是一种金属去除剂。
T5321 Itaconic anhydride

Others Others
Itaconic anhydride 是一种从可再生资源中获得的生物基材料。广泛用于金属助粘剂、合成树脂改良剂、酯化剂、除草剂、杀虫剂。
T20381 Cetyl glycol

NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525

Others Others
Cetyl glycol (NSC-71525) 有利于金属有机前体的分解、中间体 Co(2+)Fe(3+)-油酸配合物的形成以及纳米颗粒在较低温度下的成核。 Cetyl glycol 是一种可用于化妆品的还原剂。
T0664 Nicotinic acid hydrazide

Others Others
Nicotinic acid hydrazide(NAH)是烟酸的酰肼衍生物,一种杂环有机物,是过氧化物酶抑制剂,可以形成具有较强生物活性的固态金属配合物。
T20266 Tetrasodium glutamate diacetate

Glutamate diacetate tetrasodium,GLDA

Others Others
Tetrasodium glutamate diacetate (Glutamate diacetate tetrasodium) 是一种可降解螯合剂,可用作膳食成分,可从废活性污泥 (WAS) 絮凝体中提取多价金属离子,可增强废活性污泥中挥发性脂肪酸的产生。
T0666 4-Chlorosalicylic acid

4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid,4-氯水杨酸

Tyrosinase; Antibacterial; Antibiotic; Antifungal Microbiology/Virology; Proteases/Proteasome
4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) 是一种药物中间体。它抑制单酚酶和二苯酚酶活性,IC50值分别为1.89 mM 和1.10 mM。 它有抗菌活性,抑制大肠杆菌的MIC 为250 μg/mL,MBC 为500 μg/mL。
T6198 Dolutegravir

S/GSK1349572,GSK1349572,度鲁特韦,多替拉韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Dolutegravir (GSK1349572) 是口服HIV 整合酶链转移高效抑制剂,抑制 HIV-1 病毒在外周血单个核细胞中的复制。它对耐拉替拉韦的特征突变体 Y143R、Q148K、N155H 和 G140S/Q148H 具有中等活性。
T5983 o-Phenanthroline

1,10-菲罗啉,1,10-Phenanthroline

MMP; Others Others; Proteases/Proteasome
o-Phenanthroline (1,10-Phenanthroline) 是一种金属螯合剂,能够与 Fe2+形成红色螯合物,在 510 nm 处最大吸收,可防止链脲佐菌素诱导染色体畸变。它也是一种MMP 的抑制剂。
T0781 Dimercaprol

Dicaptol,二巯丙醇,Dithiopropanol,二巯基丙醇

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Dimercaprol (Dicaptol) 是一种具有抗HIV 活性的重金属中毒解毒剂。
T20346 Salicylaldoxime

Others Others
Salicylaldoxime 是一种螯合剂,有时用于分析含有过渡金属离子的样品,它通常与过渡金属离子形成色彩鲜艳的配位络合物。
T65636 BIS-TRIS propane

BTP

Others Others
BIS-TRIS propane (BTP) 是镍基和钴基自旋团簇的新型多齿配体,是一种金属螯合剂。Bis-tris propane 常作为两性离子缓冲液使用,可用于PCR、蛋白质结晶研究和MgATPase 酶活力研究。
T12593 Pyrithione

1-hydroxyl-1H-pyridine-2-thione,吡啶硫酮

Others Others
Pyrithione (1-hydroxyl-1H-pyridine-2-thione) 是一种锌离子载体,过渡金属配合物,可引起哺乳动物细胞内锌水平的升高,有杀菌和抗真菌作用。
T22428 Sodium Glucoheptonate

Sodium glucoheptonate,葡萄醣庚酸钠

Others Others
Sodium Glucoheptonate 可用作 Tc-99m 放射性标记的试剂盒,也可用于清洗金属、丝光、脱漆和铝蚀刻。其中Tc-99m glucoheptonate 是一种肾脏和脑部成像剂,可用于检测脑肿瘤。
T50056 Antibacterial agent 170

Others Others
4-(4,5-dibromo-6-oxo-1,6-dihydropyridazin-1-yl)benzene-1-sulfonamide 是一种磺酰胺衍生物,用于合成各种超分子结构的构建块,如金属有机骨架和配位聚合物。它对多种肿瘤细胞系具有抗增殖活性。
T66155 EDTA, Disodium Salt, Dihydrate

Ethylenediaminetetraacetic acid disodium dihydrate

Protease Proteases/Proteasome
EDTA, Disodium Salt, Dihydrate (Ethylenediaminetetraacetic acid disodium dihydrate) 是一种金属离子螯合剂,用作蛋白酶抑制剂。EDTA, Disodium Salt, Dihydrate 是一种对纤维素酶活性无效的分子,广泛用于蛋白质纯化。EDTA, Disodium Salt, Dihydrate 通过与金属结合,促进其排泄。
T8422 DIETHYLDITHIOCARBAMIC ACID COPPER SALT

Cupric diethyldithiocarbamate

Others Others
DIETHYLDITHIOCARBAMIC ACID COPPER SALT 是一种可用于各种金属、蛋白质和酶实验的螯合剂,也可作为络合剂合成包括杂环化合物在内的各种有机化合物,以及用作铜死亡的诱导剂。
T22443 Triglycidyl isocyanurate

Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,1,3,5-三缩水甘油-S-三嗪三酮,TGI

Apoptosis Apoptosis
Triglycidyl isocyanurate (Teroxirone) 是一种三氮烯三环氧化合物,可通过 p53的激活抑制非小细胞肺癌细胞的生长。它诱导细胞凋亡,具有抗血管生成和抗肿瘤活性,用于癌症研究。
T9524 Lanthanum trichloride

Others Others
Lanthanum trichloride 可用作分析试剂,可用作提取金属镧的原料和石油裂化催化剂。它在医药领域也有一定的作用。例如,研究表明,它对内毒素(LPS)体内作用的拮抗作用对寻找新的有效内毒素拮抗剂有一定的影响,为防治内毒素血症提供了实验依据。
T8940 KUN56321

3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-

Others Others
KUN56321 (3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-) 是一种发光剂。 KUN56321的应用包括:真空蒸镀将 KUN56321薄膜涂布在 ITO 玻璃的空穴传输层或电子传输层上。将空穴传输层或电子传输层蒸镀在薄膜上,preppg。蒸发金属电极。 KUN56321 展示了提高发光效率和降低 org 驱动电压的能力。发光器件和显示器件。
T124358 Deferoxamine

Deferoxamine B,Desferrioxamine B

Apoptosis; Antioxidant; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; oxidation-reduction
Deferoxamine(Desferrioxamine B) 是一种铁螯合剂 (结合 Fe(III) 和许多其他金属阳离子),可抑制神经元病变,可用于改减少铁在组织中的积累和沉积,可通过抑制创伤性脑损伤后的铁死亡和神经炎症来改善神经功能障碍。Desferrioxamin-B 具有抗氧化、抗增殖、抗肿瘤活性,可诱导 HIF-1α 产生,诱导癌细胞凋亡和自噬。Desferrioxamin-B 可用于治疗急性铁中毒和与 COVID-19 相关疾病。
T40403 Antioxidant 1024

MD 1024

Others Others
Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator.

化合物

DMT1 blocker 2
Cat.No: T11064
Synonym:
Target: Others
Lumogallion
Cat.No: T20984
Synonym: 荧光镓,4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid
Target: Others
Ca-DTPA trisodium salt hydrate
Cat.No: T39477
Synonym: Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
Target: Others
Pentetic Acid
Cat.No: T0420
Synonym: Acidum penteticum,Detarex,二乙烯三胺五醋酸,Detapac,DTPA,diethylenetriaminepentaacetic acid
Target: Others
Framycetin sulfate
Cat.No: T2096
Synonym: Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate
Target: Antibacterial, Antibiotic
Metallo β-lactamase ligand 1
Cat.No: T38476
Synonym:
Target: Antibacterial
Metallo-β-lactamase-IN-4
Cat.No: T60694
Synonym:
Target: Others
Metallo-β-lactamase-IN-8
Cat.No: T60914
Synonym:
Target: Others
Metalaxyl
Cat.No: T20066
Synonym: Ridomil 72WP,Allegiance,CGA48988,CGA-48988,CGA 48988,Metalaxil
Target: Others
Metalaxyl-M
Cat.No: T40816
Synonym: Metalaxyl-M,(R)-Metalaxyl
Target: Others
Metallo-β-lactamase-IN-2
Cat.No: T60370
Synonym:
Target: Others
Metallo-β-lactamase-IN-5
Cat.No: T61173
Synonym:
Target: Others
Metallo-β-lactamase-IN-7
Cat.No: T60494
Synonym:
Target: Others
Metallo-β-lactamase-IN-9
Cat.No: T72261
Synonym:
Target: Others
Metallo-β-lactamase-IN-3
Cat.No: T60282
Synonym:
Target: Others
Metallo-β-lactamase-IN-6
Cat.No: T60239
Synonym:
Target: Others
Metallo-β-lactamase-IN-11
Cat.No: T79435
Synonym:
Target: Others
Diisopropyl xanthogen disulfide
Cat.No: T31479
Synonym: NSC1339,NSC 1339,Isopropylxanthic disulfide,二硫化二异丙基黄原酸酯,NSC-1339
Target: Others
Cryptating agent 222
Cat.No: T20736
Synonym: Cryptate 222,NSC 264495,NSC-264495,NSC264495
Target: Others
MDCG sodium
Cat.No: T73718
Synonym: NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium
Target: Endogenous Metabolite
EDTA copper(II) disodium salt
Cat.No: T65167
Synonym:
Target: Antibiotic
Nitrilotriacetic acid
Cat.No: T20841
Synonym: Triglycollamic acid,Nitrilotriacetate,Nitriloacetate
Target: Others
DMT1 blocker 1
Cat.No: T11063
Synonym:
Target: Others
Potassium thioacetate
Cat.No: T22402
Synonym:
Target: Others
Ethylenediaminetetraacetic acid trisodium salt
Cat.No: T0423
Synonym: 乙二胺四乙酸三钠,Edetate Trisodium,ethylenediaminetetraacetic acid Trisodium,EDTA Trisodium,Trisodium EDTA,依地酸三钠盐,Edetate Trisodium,EDTA trisodium salt
Target: Others, Ferroptosis
o-Cresolphthalein Complexone
Cat.No: T9241
Synonym:
Target: Others
Xantphos
Cat.No: T19936
Synonym:
Target: Others
TPEN
Cat.No: T3952
Synonym: TPEDA
Target: Apoptosis, Reactive Oxygen Species, Autophagy
Emeramide
Cat.No: T15213
Synonym: BDTH2,N,N'-二(2-巯基乙基)间苯二甲酰胺
Target: Reactive Oxygen Species
Tetrakis (4-carboxyphenyl) porphyrin
Cat.No: T8813
Synonym: 中-四(4-羧基苯基)卟吩,TCPP,Tetracarboxyphenylporphine
Target: Others
Itaconic anhydride
Cat.No: T5321
Synonym:
Target: Others
Cetyl glycol
Cat.No: T20381
Synonym: NSC-71525,NSC 71525,1,2-十六烷二醇,NSC71525
Target: Others
Nicotinic acid hydrazide
Cat.No: T0664
Synonym:
Target: Others
Tetrasodium glutamate diacetate
Cat.No: T20266
Synonym: Glutamate diacetate tetrasodium,GLDA
Target: Others
4-Chlorosalicylic acid
Cat.No: T0666
Synonym: 4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid,4-氯水杨酸
Target: Tyrosinase, Antibacterial, Antibiotic, Antifungal
Dolutegravir
Cat.No: T6198
Synonym: S/GSK1349572,GSK1349572,度鲁特韦,多替拉韦
Target: HIV Protease
o-Phenanthroline
Cat.No: T5983
Synonym: 1,10-菲罗啉,1,10-Phenanthroline
Target: MMP, Others
Dimercaprol
Cat.No: T0781
Synonym: Dicaptol,二巯丙醇,Dithiopropanol,二巯基丙醇
Target: Others, HIV Protease
Salicylaldoxime
Cat.No: T20346
Synonym:
Target: Others
BIS-TRIS propane
Cat.No: T65636
Synonym: BTP
Target: Others
Pyrithione
Cat.No: T12593
Synonym: 1-hydroxyl-1H-pyridine-2-thione,吡啶硫酮
Target: Others
Sodium Glucoheptonate
Cat.No: T22428
Synonym: Sodium glucoheptonate,葡萄醣庚酸钠
Target: Others
Antibacterial agent 170
Cat.No: T50056
Synonym:
Target: Others
EDTA, Disodium Salt, Dihydrate
Cat.No: T66155
Synonym: Ethylenediaminetetraacetic acid disodium dihydrate
Target: Protease
DIETHYLDITHIOCARBAMIC ACID COPPER SALT
Cat.No: T8422
Synonym: Cupric diethyldithiocarbamate
Target: Others
Triglycidyl isocyanurate
Cat.No: T22443
Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,1,3,5-三缩水甘油-S-三嗪三酮,TGI
Target: Apoptosis
Lanthanum trichloride
Cat.No: T9524
Synonym:
Target: Others
KUN56321
Cat.No: T8940
Synonym: 3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-
Target: Others
Deferoxamine
Cat.No: T124358
Synonym: Deferoxamine B,Desferrioxamine B
Target: Apoptosis, Antioxidant, HIF, Autophagy
Antioxidant 1024
Cat.No: T40403
Synonym: MD 1024
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3S0218 Thonningianin A

Apoptosis; Others Apoptosis; Others
Thonningianin A 是从非洲草药通宁宁的甲醇提取物中,分离得到的一种鞣花素,具有抗癌和抗氧化性,涉及自由基清除、抗超氧化物形成和金属螯合。
T16042 Metaldehyde

BCL Apoptosis
Metaldehyde is used for snails and other gastropods pesticide against.
T7929 L-Aspartic Acid 4-Benzyl Ester

Others Others
L-Aspartic Acid 4-Benzyl Ester 是一种螯合剂,与金属离子形成稳定的络合物,已用于研究金属离子对酶活性的影响,以及研究金属离子在基因表达调控中的作用等。
T2958 D-(-)-Quinic acid

Quinate,Kinic acid,Chinic acid,Quinic acid,奎尼酸

Others; Endogenous Metabolite Metabolism; Others
D-(-)-Quinic acid (Kinic acid) 是一种环己基羧酸,含量与咖啡的酸度有关。
T8083 Pyridoxal 5'-​phosphate monohydrate

Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛

Others Others
Pyridoxal 5-phosphate monohydrate 是维生素B6的活性形式,也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中最重要的辅酶变异体,能够与其他变异体(如 PNP 、 PMP)发生互换。
TN1243 3-Aminocoumarin

3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine

Others Others
3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。
T4780 Quinoline-2-carboxylic acid

喹哪啶酸,Quinaldic acid,RARECHEM AL BO 1348

Others; Endogenous Metabolite Metabolism; Others
Quinaldic acid 是内源性代谢产物的一种。Quinaldic acid 是一种金属螯合剂。
T8087 Tropolone

Tyrosinase Proteases/Proteasome
Tropolone 是一种 mushroom tyrosinase 抑制剂,IC50=0.4 μM,它的抑制作用可以通过透析或过量的 CU2+逆转。它是 2 位上带有羟基的 tropone 衍生物,是许多 Azulene 衍生物的前体,如 2-methylazulene-1-carboxylate。
T7998 1,7-Diaminoheptane

Others Others
1,7-Diaminoheptane 是一种脂族胺家族的化合物。它可用于合成肽、拟肽和其他化合物,也被用作酶反应中的底物,金属配合物中的配体,以及有机合成中的试剂。
T2971 Phytic acid

Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid

Xanthine Oxidase; Endogenous Metabolite Metabolism
Phytic acid (Fytic Acid) 是种子和谷粒的磷储存化合物。它被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是钙,铁,锌和蛋白质残留物。它抑制超氧化物来源黄嘌呤氧化酶并具有抗氧化,抗炎以及神经保护作用。
T7963 2,4-Dihydroxypyridine

Others Others
2,4-Dihydroxypyridine 是一种吡啶衍生物,作为螯合剂与金属离子结合并形成络合物。它被用作测定各种离子浓度的试剂,如钙、镁和磷酸盐;也用于测量酶催化反应的速率;还用于蛋白质、碳水化合物和其他生物分子的检测和定量。

天然产物

Thonningianin A
Cat.No: T3S0218
Synonym:
Target: Apoptosis, Others
Metaldehyde
Cat.No: T16042
Synonym:
Target: BCL
L-Aspartic Acid 4-Benzyl Ester
Cat.No: T7929
Synonym:
Target: Others
D-(-)-Quinic acid
Cat.No: T2958
Synonym: Quinate,Kinic acid,Chinic acid,Quinic acid,奎尼酸
Target: Others, Endogenous Metabolite
Pyridoxal 5'-​phosphate monohydrate
Cat.No: T8083
Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛
Target: Others
3-Aminocoumarin
Cat.No: TN1243
Synonym: 3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine
Target: Others
Quinoline-2-carboxylic acid
Cat.No: T4780
Synonym: 喹哪啶酸,Quinaldic acid,RARECHEM AL BO 1348
Target: Others, Endogenous Metabolite
Tropolone
Cat.No: T8087
Synonym:
Target: Tyrosinase
1,7-Diaminoheptane
Cat.No: T7998
Synonym:
Target: Others
Phytic acid
Cat.No: T2971
Synonym: Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid
Target: Xanthine Oxidase, Endogenous Metabolite
2,4-Dihydroxypyridine
Cat.No: T7963
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03371 Transferrin Protein, Rat, Recombinant (His & KSI)

Tf,Beta-1 metal-binding globulin,Liver regeneration...

Rat E. coli
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight ...
TMPH-02373 Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)

Metallo-beta-lactamase type 2,B2 metallo-b...

Klebsiella pneumoniae E. coli
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
TMPH-01669 Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)

Metallothionein-III,Metallothionein-3,GIFB...

Human E. coli
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
TMPH-00672 Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)

stcE,Neutral zinc metalloprotease StcE,Metal

E. coli E. coli
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis. Therefore, the current model proposes two roles for StcE during infection: it acts first as...
TMPH-02402 Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)

Zinc metalloproteinase,PEP1,PRO A

Legionella pneumophila E. coli
Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.
TMPH-03488 Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)

Metallo-beta-lactamase type 2,BLA-IMP,Metal

Serratia marcescens E. coli
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P52699.
TMPH-03580 Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)

Staphylococcus aureus neutral proteinase,aur,Zinc metal<...

Staphylococcus aureus E. coli
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177.
TMPH-01670 Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)

MT4,Metallothionein-4,Metallothionein-IV

Human E. coli
Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
TMPY-02957 DYDC2 Protein, Human, Recombinant (GST)

DPY30 domain containing 2

Human E. coli
DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family inv...
TMPJ-01376 ZNF70 Protein, Human, Recombinant (His)

Zinc Finger Protein N27C7-1,Zinc Finger Protein 70,ZNF70

Human E. coli
Zinc Finger Protein 70 (ZNF70) is a member of the krueppel C2H2-type zinc-finger protein family. ZFN70 is localized to the cell nucleus and contains eleven C2H2-type zinc fingers. ZFN70 has sequence-specific DNA binding transcription factor activity, and it may be involved in transcriptional regulation. In addition, ZFN70 has the DNA-binding and metal-binding activity, which can bind zinc ion.
TMPJ-01157 LACTB2 Protein, Human, Recombinant (GST)

β-Lactamase-Like Protein 2,LACTB2,Beta-Lactamase-Like Protei...

Human E. coli
β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is expressed at high levels and annotates structural defects or features in 4 cDNA clones. LACTB2 proteins are expected to have hydrolase activity and metal ion-binding functions. LACTB2 protein is found to localize in mitochondrion. Other functions of LACTB2 is yet unknown.
TMPY-03857 MMGT1 Protein, Human, Recombinant (His)

membrane magnesium transporter 1,TMEM32,EMC5

Human HEK293 Cells
MMGT1 (Membrane Magnesium Transporter 1, also known as EMC5 and TMEM32) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein belongs to the membrane magnesium transporter (TC 1.A.67) family which is a group of magnesium transporters that are part of the TOG superfamily. It mediates Mg(2+) transport. MMGT1 is described as having 335 amino acids and five TMSs with an N-terminal cleavage site and some phosphorylation sites. It is widely expressed ...
TMPY-06226 SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

solute carrier family 39 member 6

Cynomolgus HEK293 Cells
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as a...
TMPY-01819 PDE1B Protein, Human, Recombinant (His & GST)

PDES1B,phosphodiesterase 1B, calmodulin-dependent,PDE1B1

Human Baculovirus Insect Cells
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, also known as Cam-PDE 1B and PDE1B, is a cytoplasm protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE1 subfamily. Phosphodiesterase-1A (PDE1A), Phosphodiesterase-1B (PDE1B), Phosphodiesterase-4B (PDE4B), and Phosphodiesterase-4A (PDE4A) are important regulators of signal transduction in striatum due to their catalysis of cyclic AMP and cyclic GMP. PDE1B is highly expressed in the striatum. It b...
TMPY-02209 CUTC Protein, Human, Recombinant (His)

CGI-32,cutC copper transporter

Human E. coli
Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply o...

重组蛋白

Transferrin Protein, Rat, Recombinant (His & KSI)
Cat.No: TMPH-03371
Species: Rat
Expression System: E. coli
Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)
Cat.No: TMPH-02373
Species: Klebsiella pneumoniae
Expression System: E. coli
Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01669
Species: Human
Expression System: E. coli
Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
Cat.No: TMPH-00672
Species: E. coli
Expression System: E. coli
Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)
Cat.No: TMPH-02402
Species: Legionella pneumophila
Expression System: E. coli
Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)
Cat.No: TMPH-03488
Species: Serratia marcescens
Expression System: E. coli
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Cat.No: TMPH-03580
Species: Staphylococcus aureus
Expression System: E. coli
Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01670
Species: Human
Expression System: E. coli
DYDC2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02957
Species: Human
Expression System: E. coli
ZNF70 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01376
Species: Human
Expression System: E. coli
LACTB2 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01157
Species: Human
Expression System: E. coli
MMGT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03857
Species: Human
Expression System: HEK293 Cells
SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06226
Species: Cynomolgus
Expression System: HEK293 Cells
PDE1B Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01819
Species: Human
Expression System: Baculovirus Insect Cells
CUTC Protein, Human, Recombinant (His)
Cat.No: TMPY-02209
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMIJ-0436 Metaldehyde-d16

Metaldehyde-d16 是 Metaldehyde 的氘代化合物。Metaldehyde 的 CAS 号为 108-62-3。

同位素标记化合物

Metaldehyde-d16
Cat.No: TMIJ-0436
Synonym:
Target:
TargetMol Loading
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