2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) is a naturally occurring substance found in the dried roots of Rubia cordifolia.
4-Hydroxyalternariol 9-methyl ether displays promising antioxidant effects. It also shows antibacterial activity against several tested bacterial pathogens with minimum inhibitory concentration values in the range of 86.7-364.7 uM.
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9, a quinolone alkaloid derived from Evodia rutaecarpa, is a potent antagonist of the angiotensin II receptor, displaying an IC50 value of 48.2 μM.
(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells.
2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs of Lilium brownie var. viridulum. This compound has been observed to exhibit a weak inhibition of NO production in LPS-stimulated RAW 264.7 cells.