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Search Results for " tubulin polymerization "

Targets Recommended: Apoptosis Microtubule Associated

170

抑制剂 & 化合物

13

天然产物

2

化合物库

4

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name
L1110	微管靶向化合物库		142 compounds
	142 种靶向微管的分子集合，用于高通量筛选和高内涵筛选；
L1310	细胞骨架化合物库		759 compounds
	759 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；

化合物库

微管靶向化合物库

Cat.No: L1110

Compounds: 142

细胞骨架化合物库

Cat.No: L1310

Compounds: 759

Cat. No.	Product Name	Target	Signaling Pathways
T77647	Tubulin polymerization-IN-43	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Tubulin polymerization-IN-43 是一种微管蛋白聚合 (tubulin polymerization) 抑制剂。Tubulin polymerization-IN-43 具有多种作用，通过靶向 Colchicine 位点破坏细胞微管网络，促进白血病细胞的细胞周期停滞在 G2/M 期和细胞凋亡 (apoptosis)。Tubulin polymerization-IN-43 具有抗血管生成活性。
T77651	Tubulin polymerization-IN-47	Microtubule Associated	Cytoskeletal Signaling
	Tubulin polymerization-IN-47 是一种 tubulin 聚合抑制剂和有丝分裂抑制剂，具有抗肿瘤活性，对神经母细胞瘤癌细胞增殖具有抑制作用，对 Chp-134 和 Kelly 细胞系的IC50 分别为 7 和 12 nM。Tubulin polymerization-IN-47 是治疗肝癌、结肠癌、肺癌和乳腺癌的候选化合物。
T77728	Tubulin polymerization-IN-55	Microtubule Associated	Cytoskeletal Signaling
	Tubulin polymerization-IN-55 是一种高效的 Tubulin Polymerization 抑制剂，具有潜在的抗血管生成和抗肿瘤活性，对 A549、K562、HepG2、MDA-MB-231 和 HFL-1 显示出抗增殖作用。
T9504	MAP4343	Microtubule Associated	Cytoskeletal Signaling
	MAP4343 是孕烯醇酮的 3-甲基醚衍生物。它在体外与微管相关蛋白 2 (MAP2) 结合并刺激微管蛋白聚合，从而增强神经突延伸和保护神经元免受神经毒剂的侵害。
T9595	LP-261	Microtubule Associated	Cytoskeletal Signaling
	LP-261 是一种新型的微管蛋白靶向抗癌剂，可与微管蛋白上的秋水仙碱位点结合，诱导 G2/M 期阻滞，其EC50为 3.2 μM。它可抑制人非小细胞肺癌的生长，可用于癌症研究。
T10460	Batabulin 巴他布林,T138067	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Batabulin (T138067) 是一种抗肿瘤剂，可与 β-微管蛋白同种型的子集共价且选择性地结合，从而破坏微管聚合。它影响细胞形态并导致细胞周期停滞，最终诱导细胞凋亡。
T61084	Tubulin polymerization-IN-37	Others	Others
	Tubulin polymerization-IN-37 is a potent inhibitor (IC50: 2.3 μΜ) of tubulin polymerization by binding specifically to the colchicine site of tubulin and preventing colchicine binding. It has potential applications in cancer research, notably for lymphomas [1].
T62121	Tubulin polymerization-IN-3	Others	Others
	Tubulin polymerization-IN-3 是一种有效的微管蛋白聚合抑制剂 (IC50: 3.84 μM)，能够诱导结肠癌细胞凋亡。
T79887	Tubulin polymerization-IN-49	Others	Others
	Tubulin polymerization-IN-49 (compound 12d) 是一种抑制微管蛋白聚合的有效化合物。它通过结合到微管蛋白的秋水仙碱位点来抑制其聚合。此外，Tubulin polymerization-IN-49 能够诱导细胞周期在 G2/M 期停滞并触发细胞凋亡，表现出对抗癌的活性，能够预防肿瘤的生成及抑制肿瘤增殖和血管生成。
T62498	Tubulin polymerization-IN-20	Others	Others
	Tubulin aggregation-IN-20 (compound 11) 是一种有效的 tubulin 聚合抑制剂。Tubulin aggregation-IN-20 具有潜力进行乳腺癌和耐药结肠癌的研究。
T62206	Tubulin polymerization-IN-19	Others	Others
	Tubulin aggregation-IN-19 (compound 4) 是一种有效 tubulin 聚合抑制剂，对乳腺癌和耐药结肠癌表现出研究潜力。
T62971	Tubulin polymerization-IN-16	Others	Others
	Tubulin aggregation-IN-16 (compound 5g) 是一种有效的 tubulin 聚合抑制剂。Tubulin aggregation-IN-16 对癌细胞有效 (IC50: 0.084-0.221 μM)。Tubulin aggregation-IN-16 能有效地破坏微管/管蛋白的动态，诱导 SGC-7901 细胞的细胞周期阻滞在 G2/M 期。
T63836	Tubulin polymerization-IN-7	Others	Others
	Tubulin aggregation-IN-7 是有效的 tubulin 聚合抑制剂，对癌症疾病表现出研究潜力。
T11917	Lys-SMCC-DM1 Lys-Nε-MCC-DM1	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	DM1 是一种微管蛋白抑制剂。 Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) 是 DM1 的活性代谢物。
T61940	Tubulin polymerization-IN-4	Others	Others
	Tubulin polymerization-IN-4 是有效的微管蛋白聚合体 (tubulin polymerization) 抑制剂（IC50=4.6 μM）。Tubulin polymerization-IN-4 可以破坏微管蛋白聚合，将细胞周期阻滞在G2/M 期，诱导细胞凋亡 (apoptosis)，抑制细胞的克隆发生和迁移。Tubulin polymerization-IN-4还可以破坏血管系统。
T60735	Tubulin polymerization-IN-22	Others	Others
	Tubulin aggregation-IN-22 抑制细胞周期在 G2/M 期，并且诱导细胞凋亡。Tubulin aggregation-IN-22 是一种微管蛋白聚合抑制剂 (IC50 = 8.1 μM)。
T62040	Tubulin polymerization-IN-30	Others	Others
	Tubulin polymerization-IN-30 (compound 6e) 是有效的微管蛋白聚合 (Tubulin polymerization) 抑制剂，可破坏细胞内微管组织，将细胞周期阻滞在 G2/M 期。Tubulin polymerization-IN-30 对 HeLa、SGC-7901和A549 等肿瘤细胞系具有良好的抗肿瘤活性，其IC50分别为 0.403、 2.16和2.21 μM。
T60936	Tubulin polymerization-IN-24	Others	Others
	Tubulin aggregation-IN-24 (compound HMBA) 是一种有效的微管蛋白聚合抑制剂，可提高 GTP 水解速率并抑制微管组装。Tubulin aggregation-IN-24 诱导细胞凋亡和细胞周期停滞在 G2/M 期。Tubulin aggregation-IN-24 抑制乳腺癌细胞 MCF-7 的增殖。
T61482	Tubulin polymerization-IN-13	Others	Others
	Tubulin polymerization-IN-13 (Compound 4f) is a potent inhibitor of tubulin polymerization, with an IC50 value of 0.37 μM. It displays significant anti-proliferative effects against cancer cells, inducing apoptosis and exhibiting potential antivascular activity [1].
T63849	Tubulin polymerization-IN-34	Others	Others
	Tubulin polymerization-IN-34 是 [1,2] 恶唑异吲哚微管蛋白聚合的抑制剂，能够高度选择边缘区淋巴瘤 VL51 细胞系。
T79532	Tubulin polymerization-IN-44	Others	Others
	Tubulin polymerization-IN-44 (7w)为具高效性的微管蛋白聚合抑制剂，其IC50为0.21 μM。该化合物可诱发G2/M期阻塞并触发癌细胞凋亡(apoptosis)，适用于肿瘤研究。
T62369	Tubulin polymerization-IN-17	Others	Others
	Tubulin aggregation-IN-17 (compound 23g) 是一种 tubulin 聚合的有效抑制剂。Tubulin aggregation-IN-17 具有微管蛋白解聚作用，能够诱导细胞凋亡并抑制迁移。Tubulin aggregation-IN-17 具有潜力进行癌症疾病的研究。
T61069	Tubulin polymerization-IN-15	Others	Others
	Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].
T60758	Tubulin polymerization-IN-36	Others	Others
	Tubulin polymerization-IN-36 可用于癌症研究，例如淋巴癌。Tubulin polymerization-IN-36 结合微管蛋白的秋水仙碱位点并且抑制秋水碱结合，是一种微管蛋白聚合的抑制剂，IC50值为 2.8 μM。
T61129	Tubulin polymerization-IN-27	Others	Others
	Tubulin polymerization-IN-27 (compound 5j) is an inhibitor of tubulin polymerization. It has the ability to halt the cell cycle specifically at the G2/M phase and also induce apoptosis [1].
T79429	Tubulin polymerization-IN-50	Others	Others
	Tubulin polymerization-IN-50（compound 7n）是一种Tubulin polymerization抑制剂，其在SK-Mel-28细胞中的IC50值为5.05 μM，能够诱导(cell cycle)阻滞在G2/M期。
T80922	Tubulin polymerization-IN-56	Others	Others
	Tubulin polymerization-IN-56（compound 8l），一种吲唑衍生的微管蛋白聚合抑制剂，通过与秋水仙碱位点的相互作用，能够引发细胞周期停滞与细胞凋亡。该化合物还能降低细胞迁移并在体内更有效地抑制肿瘤生长。
T72169	Tubulin polymerization-IN-40	Others	Others
	Tubulin polymerization-IN-40为基于吖啶的微管蛋白聚合抑制剂，IC50值为1.5 μM，能在G2/M期阻滞癌细胞并诱导细胞凋亡，同时显示出抗癌活性与免疫增强作用。
T79645	Tubulin polymerization-IN-48	Others	Others
	Tubulin polymerization-IN-48 (Compound 4k) 是一种中等强度破坏微管网络的微管蛋白聚合抑制剂。其对神经母细胞瘤癌细胞增殖的抑制效果显著，Chp-134 细胞系和 Kelly 细胞系的IC50值分别为79 nM和165 nM。
T62477	Tubulin polymerization-IN-18	Others	Others
	Tubulin aggregation-IN-18 (compound 3) 是一种有效的 tubulin 聚合抑制剂，具有潜力进行乳腺癌和耐药结肠癌的研究。
T79766	Tubulin polymerization-IN-52	Others	Others
	Tubulin polymerization-IN-52 (compound SC23)是一种tubulin聚合抑制剂，具有2.9 μM的IC50值。
T60902	Tubulin polymerization-IN-31	Others	Others
	Tubulin polymerization-IN-31 (Compound 4c) 具有抗癌活性，并诱导癌细胞凋亡。Tubulin polymerization-IN-31 是微管蛋白聚合的抑制剂，IC50 值为 3.64 μM。
T61600	Tubulin polymerization-IN-10	Others	Others
	Tubulin polymerization-IN-10 is a highly potent inhibitor of tubulin polymerization, exhibiting an IC50 value of 4.25±0.75 μM. It possesses significant anti-tumor properties [1].
T62135	Tubulin polymerization-IN-25	Others	Others
	Tubulin polymerization-IN-25 是一种选择性的、双重 tubulin polymerization (IC50: 1.11 μM) 和 farnesyl transferase (FTase) (IC50: 0.39 μM) 抑制剂。Tubulin polymerization-IN-25 对癌细胞表现出细胞毒性，能够阻断细胞增殖。
T79268	Tubulin polymerization-IN-42	Others	Others
	Tubulin polymerization-IN-42（compound 10j）是一种具有抗癌活性的吲哚取代呋喃酮类微管蛋白聚合抑制剂。
T61532	Tubulin polymerization-IN-6	Others	Others
	Tubulin polymerization-IN-6 (compound 5f) is a potent inhibitor of tubulin polymerization, with an IC50 of 1.09 μM. It not only inhibits cell migration and tube formation but also has anti-angiogenic properties. Additionally, Tubulin polymerization-IN-6 has been found to effectively hinder tumor growth in HT29 xenograft Balb/c nude mice [1].
T62349	Tubulin polymerization-IN-8	Others	Others
	Tubulin aggregation-IN-8 (compound IIc) 是一种有效的tubulin 聚合抑制剂。Tubulin aggregation-IN-8 浓度依赖性地导致 HCT116 肿瘤细胞 G2/M 期细胞周期停滞，并显示显着抑制微管蛋白聚合，IC50值为 12.7 μM。Tubulin aggregation-IN-8 具有研究癌症疾病的潜力。
T63580	Tubulin polymerization-IN-21	Others	Others
	Tubulin polymerization-IN-21 是微管蛋白聚合抑制剂，能够破坏细胞完整性和影响葡萄糖代谢，具有抗癌作用。
T63111	Tubulin polymerization-IN-33	Others	Others
	Tubulin polymerization-IN-33 是一种 [1,2] 恶唑洛异吲哚微管蛋白聚合的抑制剂，能够较好的抗 NCI 系列癌细胞的增殖。
T80923	Tubulin polymerization-IN-53	Others	Others
	Tubulin polymerization-IN-53 是一种β-tubulin聚合的抑制剂，能够阻断细胞周期于G2/M阶段。对MDA-MB-231细胞系显示出抗增殖作用，其IC50为3.24 μM。
T60802	Tubulin polymerization-IN-2	Others	Others
	Tubulin polymerization-IN-2 为针对β-微管蛋白的强效抗癌分子，IC50 值为0.92 μM。该分子在多种细胞系中，包括白血病、非小细胞肺癌、肾癌、前列腺癌及乳腺癌细胞中展现出显著的抑制效果。
T72167	Tubulin polymerization-IN-39	Others	Others
	Tubulin polymerization-IN-39，一种以IC50为4.9μM抑制微管蛋白聚合，通过占据秋水仙碱结合位点来实现其作用。此外，Tubulin polymerization-IN-39能有效抑制癌细胞增殖。
T62217	Tubulin polymerization-IN-9	Others	Others
	Tubulin polymerization-IN-9 是一种微管蛋白 (tubulin) 的有效抑制剂 (IC50: 1.82 μM)。Tubulin polymerization-IN-9 能够将 K562 细胞的细胞周期停滞在 G2/M 期，并诱导其凋亡 (apoptosis) 及线粒体去极化。Tubulin polymerization-IN-9 表现出强大的抗血管和抗肿瘤作用。
T63611	Tubulin polymerization-IN-32	Others	Others
	Tubulin polymerization-IN-32 是微管蛋白 (tubulin) 聚合抑制剂，能够抑制癌细胞增殖，可用于研究淋巴瘤等癌症。
T79341	Tubulin polymerization-IN-45	Others	Others
	Tubulin polymerization-IN-45 是针对微管蛋白的靶向抑制剂，通过与微管蛋白秋水仙碱结合位点相结合，能够诱导肝细胞癌细胞 (HCC) 发生细胞凋亡 (apoptosis)。
T80924	Tubulin polymerization-IN-51	Others	Others
	Tubulin polymerization-IN-51（compound 7u）是抑制SK-Mel-28细胞微管蛋白聚合的化合物，IC50介于2.55至17.89μM。该化合物适用于癌症研究。
T60600	Tubulin polymerization-IN-14	Others	Others
	Tubulin polymerization-IN-14 (Compound 20a) 是一种微管蛋白聚合抑制剂(IC 50 = 3.15 μM) ，具有强大的抗血管和抗癌活性，包括诱导癌细胞凋亡。
T62693	Tubulin polymerization-IN-29	Others	Others
	Tubulin polymerization-IN-29 是一种有效的微管蛋白聚合抑制剂，显示出有效的抗增殖效果。Tubulin polymerization-IN-29 能够诱导 HeLa 细胞的细胞周期阻滞在 G2/M 期。
T63725	Tubulin polymerization-IN-35	Others	Others
	Tubulin polymerization-IN-35 是 [1,2] 恶唑异吲哚微管蛋白聚合的抑制剂，能够高度选择性作用于边缘区淋巴瘤 VL51 细胞系。
T61880	Tubulin polymerization-IN-26	Others	Others
	Tubulin polymerization-IN-26 (compound 12h) is a chemical compound that inhibits the polymerization of microtubulin. It achieves this by binding to the colchicine binding site of microtubulin, with an IC50 value of 4.64 μM. Additionally, Tubulin polymerization-IN-26 has the ability to induce apoptosis and inhibit cell metastasis or migration. Due to these properties, it holds potential as a valuable compound for researching lung cancer [1].

化合物

Tubulin polymerization-IN-43

Cat.No: T77647

Target: Apoptosis, Microtubule Associated

Tubulin polymerization-IN-47

Cat.No: T77651

Target: Microtubule Associated

Tubulin polymerization-IN-55

Cat.No: T77728

Target: Microtubule Associated

Cat.No: T9504

Target: Microtubule Associated

Cat.No: T9595

Target: Microtubule Associated

Cat.No: T10460

Synonym: 巴他布林,T138067

Target: Apoptosis, Microtubule Associated

Tubulin polymerization-IN-37

Cat.No: T61084

Target: Others

Tubulin polymerization-IN-3

Cat.No: T62121

Target: Others

Tubulin polymerization-IN-49

Cat.No: T79887

Target: Others

Tubulin polymerization-IN-20

Cat.No: T62498

Target: Others

Tubulin polymerization-IN-19

Cat.No: T62206

Target: Others

Tubulin polymerization-IN-16

Cat.No: T62971

Target: Others

Tubulin polymerization-IN-7

Cat.No: T63836

Target: Others

Cat.No: T11917

Synonym: Lys-Nε-MCC-DM1

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Tubulin polymerization-IN-4

Cat.No: T61940

Target: Others

Tubulin polymerization-IN-22

Cat.No: T60735

Target: Others

Tubulin polymerization-IN-30

Cat.No: T62040

Target: Others

Tubulin polymerization-IN-24

Cat.No: T60936

Target: Others

Tubulin polymerization-IN-13

Cat.No: T61482

Target: Others

Tubulin polymerization-IN-34

Cat.No: T63849

Target: Others

Tubulin polymerization-IN-44

Cat.No: T79532

Target: Others

Tubulin polymerization-IN-17

Cat.No: T62369

Target: Others

Tubulin polymerization-IN-15

Cat.No: T61069

Target: Others

Tubulin polymerization-IN-36

Cat.No: T60758

Target: Others

Tubulin polymerization-IN-27

Cat.No: T61129

Target: Others

Tubulin polymerization-IN-50

Cat.No: T79429

Target: Others

Tubulin polymerization-IN-56

Cat.No: T80922

Target: Others

Tubulin polymerization-IN-40

Cat.No: T72169

Target: Others

Tubulin polymerization-IN-48

Cat.No: T79645

Target: Others

Tubulin polymerization-IN-18

Cat.No: T62477

Target: Others

Tubulin polymerization-IN-52

Cat.No: T79766

Target: Others

Tubulin polymerization-IN-31

Cat.No: T60902

Target: Others

Tubulin polymerization-IN-10

Cat.No: T61600

Target: Others

Tubulin polymerization-IN-25

Cat.No: T62135

Target: Others

Tubulin polymerization-IN-42

Cat.No: T79268

Target: Others

Tubulin polymerization-IN-6

Cat.No: T61532

Target: Others

Tubulin polymerization-IN-8

Cat.No: T62349

Target: Others

Tubulin polymerization-IN-21

Cat.No: T63580

Target: Others

Tubulin polymerization-IN-33

Cat.No: T63111

Target: Others

Tubulin polymerization-IN-53

Cat.No: T80923

Target: Others

Tubulin polymerization-IN-2

Cat.No: T60802

Target: Others

Tubulin polymerization-IN-39

Cat.No: T72167

Target: Others

Tubulin polymerization-IN-9

Cat.No: T62217

Target: Others

Tubulin polymerization-IN-32

Cat.No: T63611

Target: Others

Tubulin polymerization-IN-45

Cat.No: T79341

Target: Others

Tubulin polymerization-IN-51

Cat.No: T80924

Target: Others

Tubulin polymerization-IN-14

Cat.No: T60600

Target: Others

Tubulin polymerization-IN-29

Cat.No: T62693

Target: Others

Tubulin polymerization-IN-35

Cat.No: T63725

Target: Others

Tubulin polymerization-IN-26

Cat.No: T61880

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6706	3-demethylcolchicine 3-去甲秋水仙碱,3-去甲基秋水仙碱	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	3-Demethylcolchicine 是一种从金莲花中分离得到的天然产物，对纯化的牛脑微管蛋白的聚合有抑制作用。
T6272	Fosbretabulin Disodium Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Fosbretabulin Disodium (CA 4P) 是一种微管蛋白去稳定剂，是 Combretastatin A4 前药，可选择性靶向内皮细胞，诱导新生肿瘤新血管消退，减少肿瘤血流量并引起中央肿瘤坏死。
TP1180	Dolastatin 10 尾海兔素10,NSC 376128,DLS 10	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	Dolastatin 10 (DLS 10) 是一种多肽，可以抑制微管蛋白聚合，显示除抗有丝分裂的活性。
T22262	Ansamitocin p-3 Maytansinol isobutyrate,Antibiotic C 15003P3,NSC292222	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	Ansamitocin p-3 (Maytansinol isobutyrate) 是一种微管抑制剂，对微管蛋白聚合的 IC50 为 3.4 μM。
T75646	Moroidin	Others	Others
	Moroidin是一种双环八肽，隶属于荨麻疹科环肽科，有效抑制纯化的微管蛋白聚合，表现为微管蛋白聚合抑制剂。此外，Moroidin对包括A549人肺癌细胞在内的多种癌细胞显示出细胞毒性作用，能诱导细胞凋亡。
T13944	Tubulysin M	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Tubulysin M is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin M is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce
T13941	Tubulysin G	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Tubulysin G is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin G is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce
T82241	Halichondrin B
	Halichondrin B，源自海绵 Halichondria okadai，为非竞争性Vinca-alkaloid 微管蛋白结合抑制剂，微管蛋白聚合 IC50 值为1.2-1.4 μM，表现出抗肿瘤活性。
T82787	Calythropsin
	Calythropsin是一种对有丝分裂产生微弱影响的细胞毒性查尔酮类化合物，该化合物可能还会影响微管蛋白的聚合。
T82857	Blestriarene B (-)-Blestriarene B
	(-)-Blestriarene B 是一种从白芨（兰科）中分离得到的二苯乙烯类化合物，其通过抑制微管蛋白的聚合作用发挥效用。
T13940	Tubulysin F	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Tubulysin F is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin F is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce
T13943	Tubulysin I	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Tubulysin I is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin I is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to c
T13942	Tubulysin H	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Tubulysin H is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin H is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce

天然产物

3-demethylcolchicine

Cat.No: TN6706

Synonym: 3-去甲秋水仙碱,3-去甲基秋水仙碱

Target: Reactive Oxygen Species

Fosbretabulin Disodium

Cat.No: T6272

Synonym: Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium

Target: Apoptosis, Microtubule Associated

Cat.No: TP1180

Synonym: 尾海兔素10,NSC 376128,DLS 10

Target: Microtubule Associated, ADC Cytotoxin

Ansamitocin p-3

Cat.No: T22262

Synonym: Maytansinol isobutyrate,Antibiotic C 15003P3,NSC292222

Target: Microtubule Associated, ADC Cytotoxin

Cat.No: T75646

Target: Others

Cat.No: T13944

Target: Others, ADC Cytotoxin

Cat.No: T13941

Target: Others, ADC Cytotoxin

Cat.No: T82241

Cat.No: T82787

Cat.No: T82857

Synonym: (-)-Blestriarene B

Cat.No: T13940

Target: Others, ADC Cytotoxin

Cat.No: T13943

Target: Others, ADC Cytotoxin

Cat.No: T13942

Target: Others, ADC Cytotoxin

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03397	TPPP3 Protein, Human, Recombinant (His) CGI-38,TPPP3,p25gamma,tubulin polymerization	Human	E. coli
	TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons, Tppp3 is expressed in cells at the circumference of the developing tendons, likely the progenitors of connective tissues that surround tendons: the tendon sheath, epitenon, and paratenon. Tppp3 is also expressed in forming synovial joints. The onset of Tppp3 expression in joint...
TMPY-04110	TPPP2 Protein, Human, Recombinant (His) P18,p25β,CT152,tubulin polymerization-prom...	Human	E. coli
	TPPP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.3 kDa and the accession number is AAH38970.1.
TMPJ-01387	PACSIN2 Protein, Human, Recombinant (His) Protein Kinase C and Casein Kinase Substrate in Neurons Prot...	Human	HEK293 Cells
	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymeri...
TMPY-03047	Stathmin 1 Protein, Human, Recombinant (His) SMN,OP18,stathmin 1,LAP18,C1orf215,PP17,Lag,PP19,PR22	Human	E. coli
	Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and prom...

重组蛋白

TPPP3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03397

Species: Human

Expression System: E. coli

TPPP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04110

Species: Human

Expression System: E. coli

PACSIN2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01387

Species: Human

Expression System: HEK293 Cells

Stathmin 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03047

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0195	Colchicine-d6
	Colchicine-d6 是 Colchicine 的氘代化合物。Colchicine 的 CAS 号为 64-86-8。Colchicine 是微管蛋白抑制剂和微管干扰剂，通过与微管蛋白结合来阻断微管的聚合，IC50值为 3 nM。它还是α3甘氨酸受体的竞争性拮抗剂。
T71055	Albendazole-d7
	Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben...

同位素标记化合物

Cat.No: TMIJ-0195

Cat.No: T71055

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