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Search Results for " phosphoinositide 3-kinase "

Targets Recommended: PI3K

136

抑制剂 & 化合物

30

天然产物

63

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T3190	PIK-inhibitors MDK34597	PI3K	PI3K/Akt/mTOR signaling
	PIK-inhibitors (MDK34597) 是一种泛 PI3K 抑制剂，是 PI-103 的类似物。
T4219	Autophinib	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Autophinib 是一种选择性细胞自噬抑制剂，通过靶向 VPS34来抑制饥饿或雷帕霉素诱导的细胞自噬，对于饥饿和雷帕霉素诱导的自噬，IC50值分别为 90 nM 和 40 nM。它还是 ATP 竞争性 VPS34抑制剂，其 IC50值为 19 nM。
T9460	iMDK	PI3K	PI3K/Akt/mTOR signaling
	iMDK 是PI3K 抑制剂，能够抑制生长因子MDK。它能够与 MEK 抑制剂协同抑制非小细胞肺癌，而不会伤害正常细胞和小鼠。
T6757	AMG319	PI3K	PI3K/Akt/mTOR signaling
	AMG319 是一种PI3Kδ选择性抑制剂，其 IC50=18 nM。
T22377	NIBR-17	PI3K	PI3K/Akt/mTOR signaling
	NIBR-17 是一种泛 I 类 PI3K 抑制剂。 NIBR-17 抑制 PI3KKα、PI3KKβ、PI3KKγ 和 PI3KKδ，IC50 分别为 1 nM、9.2 nM、9 nM 和 20 nM。
T2083	PI-3065 PI3065	DNA-PK; PI3K; mTOR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	PI-3065 是一种有效的PI3K p110δ抑制剂(IC50=5 nM;Ki=1.5 nM)。它对 p110α，p110β，p110γ 的作用较弱，IC50分别为 910，600，>10000 nM。
T15592	IPI-3063	PI3K	PI3K/Akt/mTOR signaling
	IPI-3063 是一种选择性 PI3K p110δ抑制剂，其 IC50=2.5±1.2 nM。
T6208	AS-252424	Casein Kinase; PI3K	Metabolism; PI3K/Akt/mTOR signaling; Stem Cells
	AS252424 是一种有效的、选择性的 PI3Kγ 抑制剂，其 IC50=30±10 nM。
T2619	CH5132799	PI3K; mTOR	PI3K/Akt/mTOR signaling
	CH5132799 是一种选择性的 I 类PI3K 抑制剂。它能够抑制 PI3Kα，其 IC50=14 nM。
T6773	AZD8186	PI3K	PI3K/Akt/mTOR signaling
	AZD8186 是 PI3K 抑制剂，能够抑制 PI3Kβ (IC5050=4 nM)，PI3Kδ (IC5050=12 nM)，PI3Kα (其 IC50=35 nM) 和 PI3Kγ (其 IC50=675 nM)。
T2418	A66	PI3K	PI3K/Akt/mTOR signaling
	A66 是高效的、特异性的、选择性 p110α 抑制剂，其 IC50=32 nM。
T1949	CZC24832	PI3K	PI3K/Akt/mTOR signaling
	CZC24832 是一种PI3Kγ选择性抑制剂，其 IC50=27 nM，Kdapp=19 nM。
TQ0229	ETP-46321	PI3K	PI3K/Akt/mTOR signaling
	ETP-46321 是 PI3Kα和PI3Kδ抑制剂，Kiapp 分别为 2.3 和 14.2 nM。
T2672	TG100-115	PI3K	PI3K/Akt/mTOR signaling
	TG100-115 是 PI3Kγ/PI3Kδ 的选择性抑制剂，IC50分别为 83 和 235 nM。
T2461	PIK-90	DNA-PK; PI3K	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	PIK90 PIK-90 是一种 DNA-PK 和 PI3K 抑制剂，抑制 p110α、p110γ和DNA-PK，IC50分别为 11、18 和 13 nM。
T2297	PIK-294 PIK294	PI3K	PI3K/Akt/mTOR signaling
	PIK-294 是一种有效的p110δ选择性抑制剂，其 IC50=10 nM。
T13119	Tenalisib RP6530	PI3K	PI3K/Akt/mTOR signaling
	Tenalisib (RP6530) 是一种新颖的，高效的，选择性的 PI3Kδ (IC50:25 nM) 和 PI3Kγ (IC50:33 nM) 抑制剂。
T3348	PIK-293 PIK293	PI3K	PI3K/Akt/mTOR signaling
	PIK-293 是一种 IC87114 的类似物，是一种 PI3K 的抑制剂，其对 p110δ (IC50:0.24 μM)、p110β (IC50:10 μM)、p110γ (IC50:25 μM) 和 p110α (IC50:100 μM)。
T13386	Zandelisib	PI3K	PI3K/Akt/mTOR signaling
	Zandelisib 是PI3K 抑制剂，对p110δ选择性抑制，IC50为 3.5 nM。它显示出抗肿瘤作用。
T3986	SF2523	DNA-PK; Epigenetic Reader Domain; PI3K; mTOR	Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	SF2523 是一种选择性PI3K 抑制剂，抑制DNA-PK、PI3Kα、PI3Kγ、BRD4 和 mTOR，IC50分别为 9 nM、34 nM、158 nM、241 nM 和 280 nM。
T12831L	SAR405	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	SAR-405 是一种选择性 PIK3C3/Vps34 抑制剂，IC50为1.2 nM，Kd 为1.5 nM，可防止自噬并与肿瘤细胞中的 MTOR 抑制协同作用。它抑制饥饿或 mTOR 抑制诱导的自噬，具有抗癌活性。
T6168	ZSTK474	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	ZSTK474 是 ATP 竞争性的泛 I 类PI3K 抑制剂，抑制 PI3Kα、PI3Kβ、PI3Kδ 和 PI3Kγ，IC50分别为 16 nM、44 nM、4.6 nM 和 49 nM。它是一种可口服的 s-三嗪衍生物，具有抗肿瘤活性。
T2661	TGX-221 TGX221	PI3K	PI3K/Akt/mTOR signaling
	TGX-221 是一种选择性的、高效的、细胞膜渗透的 PI3K p110β 抑制剂，常用于研究癌症。
T8461	SKI V	Apoptosis; PI3K; S1P Receptor	Apoptosis; GPCR/G Protein; PI3K/Akt/mTOR signaling
	SKI V 是一种非竞争性非脂质鞘氨醇激酶抑制剂，对 GST-hSK 的IC50为 2 μM。它减少有丝分裂的第二信使鞘氨醇-1-磷酸的形成，可诱导细胞凋亡并具有抗肿瘤活性。它还抑制PI3K，对 hPI3k 的IC50为 6 μM。
T6774	AZD-8835 AZD8835	PI3K	PI3K/Akt/mTOR signaling
	AZD-8835 是选择性的 PI3Kα (IC50:6.2 nM) 和 PI3Kδ (IC50:5.7 nM) 抑制剂。
T6433	CAY10505	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	CAY10505 是 AS-252424 的一种脱羟基形式，是作用于神经元细胞的选择性 PI3Kγ抑制剂，IC50为 33 nM。
T14944	CGS 15943	PI3K; Adenosine Receptor	GPCR/G Protein; Neuroscience; PI3K/Akt/mTOR signaling
	CGS 15943 是一种可口服的非黄嘌呤腺苷受体拮抗剂。在转染的 CHO 细胞中，其对人 A1、A2A、A2B 和 A3 腺苷受体的 Ki 分别为 3.5、4.2、16 和 50 nM。
T3985	GDC-0326 GDC 0326,GDC0326	PI3K	PI3K/Akt/mTOR signaling
	GDC-0326是一种有效，选择性的 PI3Kα抑制剂，Ki=0.2 nM。
T6799	IITZ-01	Apoptosis; PI3K; Autophagy	Apoptosis; Autophagy; PI3K/Akt/mTOR signaling
	IITZ-01 是一个具有抗肿瘤活性的亲溶酶体自噬抑制剂，其对 PI3Kγ 的 IC50值为 2.62 μM。
T2660	IC-87114 IC 87114	PI3K	PI3K/Akt/mTOR signaling
	IC-87114 是一种有效的、选择性的PI3Kδ抑制剂，其 IC50=0.5 μM。
T13862	Recilisib RECILISIB 钠盐,Ex-RAD,ON 01210	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Recilisib (ON 01210) 是辐射防护剂，能够提高细胞中AKT 和PI3K 的活性。
T6938	PF-4989216 PF 4989216	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	PF-4989216 是一种有效的选择性 PI3K 抑制剂，对 p110α、p110β、p110γ、p110δ 和 VPS34 的 IC50 分别为 2 nM、142 nM、65 nM、1 nM 和 110 nM。
T5166	Leniolisib CDZ173	DNA-PK; PI3K	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Leniolisib (CDZ173) 是一种高效的，选择性的 PI3Kδ抑制剂，有用于免疫缺陷类疾病的研究潜力。
TQ0044	Seletalisib UCB5857	PI3K	PI3K/Akt/mTOR signaling
	Seletalisib (UCB5857) 是一种有效的、选择性的 PI3Kδ抑制剂，其 IC50=12 nM。
T4296	MTX-211 MTX 211	EGFR; PI3K	Angiogenesis; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	MTX-211 是EGFR 和PI3K 的双重抑制剂，可用于癌症和其他疾病研究。
T7879	TASP0415914	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	TASP0415914 是一种具有口服活性的 PI3Kγ抑制剂，其 IC50=29 nM。它是一种 Akt 抑制剂，其 IC50=294 nM。它可用于研究炎症性疾病。
T5432	Eganelisib IPI-549	PI3K	PI3K/Akt/mTOR signaling
	Eganelisib (IPI-549) 是 PI3Kγ的选择性抑制剂，其 IC50=16 nM，选择性是其他脂类和蛋白质激酶的 100 倍以上。
T2308	HS-173 HS 173,HS173	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	HS-173 是一种新颖的PI3K 抑制剂，可研究癌症。
T2073	GSK2636771 GSK 2636771,GSK-2636771	PI3K	PI3K/Akt/mTOR signaling
	GSK2636771 是选择性的、口服有效的PI3Kβ抑制剂，Ki=0.89 nM，IC50=5.2 nM，比p110α和p110γ的选择性高900倍，比p110δ同种型的选择性高10倍。
T3692	GNE-477 GNE 477	PI3K; mTOR	PI3K/Akt/mTOR signaling
	GNE-477 是一种高效的双重PI3K(IC50=4 nM)、mTOR(Ki=21 nM) 抑制剂。
T7166	GNE-493	PI3K; mTOR	PI3K/Akt/mTOR signaling
	GNE-493 是选择性的PI3K/mTOR 抑制剂，能够抑制 PI3Kα (IC50:3.4 nM)，PI3Kβ (IC50:12 nM)，PI3Kδ (IC50:16 nM)，PI3Kγ (IC50:16 nM) 和 mTOR (IC50:32 nM)。
T16355	NSC781406	PI3K; mTOR	PI3K/Akt/mTOR signaling
	NSC781406是一种高效PI3K 和mTOR 抑制剂，其PI3Kα的IC50值为2 nM。
T13376	YS-49	RAAS; Akt; PI3K; Adrenergic Receptor	Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Neuroscience; PI3K/Akt/mTOR signaling
	YS-49 是一种PI3K/Akt(RhoA 的下游靶标) 的激活剂，可减少 3-甲基胆碱处理的细胞中 RhoA/PTEN 的激活。它是异喹啉化合物生物碱，因能激活心脏β-adrenoceptors 而具有强烈的正性肌力作用。它能通过诱导血红素加氧酶来抑制血管紧张素 II 刺激 VSMC 细胞的增殖。
T6557	KU-0060648 KU0060648	DNA-PK; PI3K; mTOR	DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	KU-0060648 是一种 PI3K 和 DNA-PK 的双重抑制剂，对 PI3Kα、PI3Kβ、PI3Kδ、PI3Kγ 和 DNA-PK 的 IC50值分别为 4 nM、0.5 nM、0.1 nM、0.59 nM 和 8.6 nM。
T7343	PF-04979064	PI3K; mTOR	PI3K/Akt/mTOR signaling
	PF-04979064 是一种选择性 PI3K/mTOR 双重激酶抑制剂，能够抑制 PI3Kα (Ki=0.13 nM) 和 mTOR (Ki=1.42 nM)。
T6110	YM-201636	Influenza Virus; PI3K; Autophagy	Autophagy; Microbiology/Virology; PI3K/Akt/mTOR signaling
	YM201636 是是一种特异性 PIKfyve 抑制剂，IC50值为 33 nM，对 p110α的IC50为 3.3 μM。它还可抑制逆转录病毒复制。
T28416	PIK-108 PIK 108,PIK108	PI3K	PI3K/Akt/mTOR signaling
	PIK-108 是选择性的、变构的、非 ATP 竞争性的 p110β/p110δ 抑制剂。
T6704	TG 100713 TG100713	PI3K	PI3K/Akt/mTOR signaling
	TG 100713 是一种PI3K 的抑制剂，抑制PI3Kδ，γ，α和β的IC50值分别为24、50、165 和 215 nM。
T12115	MSC2360844	PI3K	PI3K/Akt/mTOR signaling
	MSC2360844 是一种选择性的、具有口服活性的PI3Kδ抑制剂，其 IC50=145 nM。它对一组 278 种其他激酶显示出高度选择性。
T21938	AS-041164	PI3K	PI3K/Akt/mTOR signaling
	AS-041164 是选择性的，具有口服活性的PI3Kγ亚型抑制剂，IC50=70 nM。它对 PI3Kα (IC50:240 μM)，PI3Kβ (IC50:1.45 μM) 和 PI3Kδ (IC50:1.70 μM) 的活性较低。它具有抗炎活性。

化合物

Cat.No: T3190

Synonym: MDK34597

Target: PI3K

Cat.No: T4219

Target: PI3K, Autophagy

Cat.No: T9460

Target: PI3K

Cat.No: T6757

Target: PI3K

Cat.No: T22377

Target: PI3K

Cat.No: T2083

Synonym: PI3065

Target: DNA-PK, PI3K, mTOR

Cat.No: T15592

Target: PI3K

Cat.No: T6208

Target: Casein Kinase, PI3K

Cat.No: T2619

Target: PI3K, mTOR

Cat.No: T6773

Target: PI3K

Cat.No: T2418

Target: PI3K

Cat.No: T1949

Target: PI3K

Cat.No: TQ0229

Target: PI3K

Cat.No: T2672

Target: PI3K

Cat.No: T2461

Target: DNA-PK, PI3K

Cat.No: T2297

Synonym: PIK294

Target: PI3K

Cat.No: T13119

Synonym: RP6530

Target: PI3K

Cat.No: T3348

Synonym: PIK293

Target: PI3K

Cat.No: T13386

Target: PI3K

Cat.No: T3986

Target: DNA-PK, Epigenetic Reader Domain, PI3K, mTOR

Cat.No: T12831L

Target: PI3K, Autophagy

Cat.No: T6168

Target: PI3K, Autophagy

Cat.No: T2661

Synonym: TGX221

Target: PI3K

Cat.No: T8461

Target: Apoptosis, PI3K, S1P Receptor

Cat.No: T6774

Synonym: AZD8835

Target: PI3K

Cat.No: T6433

Target: Apoptosis, PI3K

Cat.No: T14944

Target: PI3K, Adenosine Receptor

Cat.No: T3985

Synonym: GDC 0326,GDC0326

Target: PI3K

Cat.No: T6799

Target: Apoptosis, PI3K, Autophagy

Cat.No: T2660

Synonym: IC 87114

Target: PI3K

Cat.No: T13862

Synonym: RECILISIB 钠盐,Ex-RAD,ON 01210

Target: Akt, PI3K

Cat.No: T6938

Synonym: PF 4989216

Target: Apoptosis, PI3K

Cat.No: T5166

Synonym: CDZ173

Target: DNA-PK, PI3K

Cat.No: TQ0044

Synonym: UCB5857

Target: PI3K

Cat.No: T4296

Synonym: MTX 211

Target: EGFR, PI3K

Cat.No: T7879

Target: Akt, PI3K

Cat.No: T5432

Synonym: IPI-549

Target: PI3K

Cat.No: T2308

Synonym: HS 173,HS173

Target: Apoptosis, PI3K

Cat.No: T2073

Synonym: GSK 2636771,GSK-2636771

Target: PI3K

Cat.No: T3692

Synonym: GNE 477

Target: PI3K, mTOR

Cat.No: T7166

Target: PI3K, mTOR

Cat.No: T16355

Target: PI3K, mTOR

Cat.No: T13376

Target: RAAS, Akt, PI3K, Adrenergic Receptor

Cat.No: T6557

Synonym: KU0060648

Target: DNA-PK, PI3K, mTOR

Cat.No: T7343

Target: PI3K, mTOR

Cat.No: T6110

Target: Influenza Virus, PI3K, Autophagy

Cat.No: T28416

Synonym: PIK 108,PIK108

Target: PI3K

Cat.No: T6704

Synonym: TG100713

Target: PI3K

Cat.No: T12115

Target: PI3K

Cat.No: T21938

Target: PI3K

Cat. No.	Product Name	Target	Signaling Pathways
T4S1796	Heterophyllin B	PI3K	PI3K/Akt/mTOR signaling
	Heterophyllin B 是一种活性环肽，从 Pseudostellaria heterophylla 中分离得到，可用于研究食管癌。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
TN1134	Euscaphic acid	Apoptosis; LDL; PI3K; DNA/RNA Synthesis; NO Synthase; Prostaglandin Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; PI3K/Akt/mTOR signaling
	Euscaphic acid 是来源于枣的一种三萜，是DNA 聚合酶抑制剂，可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
T2836	Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin	MEK; PI3K; Endogenous Metabolite	MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮，可通过抑制MEK1和PI3K 来抑制皮肤癌。
TN4673	(+)-Nortrachelogenin Wikstromol,荛花酚	Apoptosis; HIV Protease; PI3K; Antifection	Apoptosis; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	(+)-Nortrachelogenin 是一种从 Wikstroemia indica C.A. Meyer （百里香科）中分离出来的木脂素。 (+)-Nortrachelogenin 具有抗白血病活性。
T5654	Musk ketone	Others	Others
	Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性，因此可能被证明是有用的癌症化学保护剂。
T6630	Quercetin Dihydrate 槲皮素,Sophoretin	Apoptosis; PI3K	Apoptosis; PI3K/Akt/mTOR signaling
	Quercetin Dihydrate (Sophoretin) 是一种黄酮类天然产物，可激活或抑制许多蛋白质的活性。它可激活 SIRT1，也可抑制PI3K，抑制 PI3K γ、PI3K δ和PI3K β 的IC50值分别为 2.4 μM、3.0 μM 和 5.4 μM。
T2174	Quercetin 槲皮素,Sophoretin	Apoptosis; Mitophagy; Reactive Oxygen Species; PI3K; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Quercetin 属于黄酮类天然产物，是 SIRT1 的激动剂；Quercetin 也是一种 PI3K 抑制剂，抑制 PI3Kγ、PI3Kδ 和 PI3Kβ (IC50=2.4/3.0/5.4 μM)。Quercetin 作为公认的热休克蛋白抑制剂，也可通过下调Hsp70或Hsp90来显著减少TII模型中的外泌体释放。
T1879	3-Methyladenine 3-MA,3-甲基腺嘌呤,NSC 66389	Mitophagy; PI3K; Endogenous Metabolite; Autophagy	Autophagy; Metabolism; PI3K/Akt/mTOR signaling
	3-Methyladenine (3-MA) 是一种 PI3K 抑制剂，选择性抑制 IB 类 PI3Kγ (IC50=60 μM) 和 III 类 VPS34 (IC50=25 μM)。3-Methyladenine 具有自噬抑制活性。
T2798	Esculetin 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin	Lipoxygenase; Akt; PI3K	Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
	Esculetin (Cichorigenin) 是主要提取自水曲柳的树皮中的活性成分。它能够抑制PI3K/Akt 途径，阻碍血小板衍生生长因子诱导的气道平滑肌细胞表型转换。它具有抗氧化，抗炎和抗肿瘤的活性。
T2746	Sophocarpine monohydrate 槐果碱,Sophocarpine,槐果碱水合物	Apoptosis; Influenza Virus; Akt; PI3K; AMPK; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Sophocarpine monohydrate 是从传统草药苦参中提取的一种重要生物碱，具有抗肿瘤活性，可用于肝细胞癌，前列腺癌和结肠直肠癌。苦参具有抗病毒，抗肿瘤和抗炎等多种药理作用。
T4S0498	Glaucocalyxin A 蓝萼甲素,Wangzaozin B,Leukamenin F	Apoptosis; Akt; Caspase; PI3K	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜，具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位，诱导骨肉瘤凋亡。
TN2019	Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮	BCL; Caspase; PI3K	Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K，对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
TN1405	Arnicolide D 山金车内酯 D,山金车内酯D	Akt; Caspase; PI3K; STAT; mTOR	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Arnicolide D 是从石胡荽中分离出的一种倍半萜内酯，以浓度和时间依赖性方式抑制鼻咽癌细胞活力。它调节细胞周期，激活 caspase 信号通路并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路。
T3826	Polygalasaponin F 异牡荆苷,瓜子金皂苷己	NF-κB; TLR; Akt; PI3K	Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
	Polygalasaponin F 是从瓜子金中提取的齐墩果烷型三萜皂苷，可通过调节TLR4-PI3K/AKT-NF-kB 信号通路减少神经炎症细胞因子的分泌，能降低炎性细胞因子肿瘤坏死因子 α 的释放。
T3780	Oroxin B Hypocretin-2,木蝴蝶苷B	Apoptosis; PTEN; Antioxidant; PI3K; Autophagy	Apoptosis; Autophagy; oxidation-reduction; PI3K/Akt/mTOR signaling
	Oroxin B (Hypocretin-2) 是从传统中草药木蝴蝶中分离出来的黄酮类天然产物，在恶性淋巴瘤细胞中诱导肿瘤抑制性 ER 应激。它通过上调 PTEN，下调 COX-2，VEGF，PI3K 和 p-AKT，对肝癌细胞具有明显的抑制作用，诱导细胞早期凋亡。
TN1299	Desmethylglycitein 4',6,7-三羟基异黄酮,4',6,7-三羟异黄酮,6-羟基大豆苷元,6,7,4'-Trihydroxyisoflavone	PI3K; CDK; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) 是大豆中苷元的代谢产物，具有抗氧化性和抗癌活性。它是蛋白激酶 C(PKC)α 的直接抑制剂，抑制正常人皮肤成纤维细胞中的太阳紫外线诱导的基质金属蛋白酶1。它在体内直接结合CDK1和CDK2，抑制 CDK1 和 CDK2 活性。
T4867	Erucic acid Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K; Endogenous Metabolite	Metabolism; PI3K/Akt/mTOR signaling
	Erucic acid (13(Z)-Docosenoic Acid) 是单不饱和脂肪酸，分离自萝卜的种子。Erucic acid 可以容易地穿过血脑屏障，使大脑中长链脂肪酸的积累正常化。Erucic acid 能够改善认知障碍并有效预防痴呆。
T5740	25(R,S)-Ruscogenin (25RS)鲁斯可皂苷元,(25RS)-Ruscogenin	Others; HIF	Angiogenesis; Chromatin/Epigenetic; Others
	25(R,S)-Ruscogenin 能够调节 PI3K/Akt/mTOR 信号通路，抑制 MMP-2、MMP-9、uPA、VEGF 和 HIF-1α 的表达，阻碍肝癌转移。它能够抑制 TLR4信号通路，减轻 LPS 诱导的肺内皮细胞凋亡。
T2P2806	Hederacolchiside A1 黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13	Apoptosis; ERK; MEK; Akt; PI3K; Parasite; mTOR	Apoptosis; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Hederacolchiside A1 (Raddeanoside R13) 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。
T3675	1-Deoxynojirimycin Duvoglustat,Moranoline,1-脱氧野尻霉素,moranolin	PI3K; Glucosidase	Metabolism; PI3K/Akt/mTOR signaling
	1-Deoxynojirimycin (Moranoline) 是一种口服具有活性的 α-葡萄糖苷酶抑制剂。它具有降血糖、减肥和抗病毒的活性。它抑制餐后血糖，预防糖尿病。
T3P2904	α-Linolenic acid Alpha-Linolenic Acid,Linolenic acid,α-亚麻酸	Akt; PI3K	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	α-Linolenic acid (Alpha-Linolenic Acid) 是一种必需脂肪酸，人体无法合成，从种子油中分离得到。它可调节 PI3K/Akt 信号传导，影响血栓形成过程。它具有抗心律失常的特性，并且与心血管疾病和癌症等有关。
T5736	1,3-Dicaffeoylquinic acid CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species; Akt; PI3K	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	1,3-Dicaffeoylquinic acid (CYNARIN) 是一种咖啡酰奎宁酸衍生物，具有抗氧化、自由基清除作用。
T2163	Dihydrocapsaicin CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others; TRP/TRPV Channel	Membrane transporter/Ion channel; Others
	Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素，是TRPV1的选择性激动剂，同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。
T3208	Brevianamide F Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)	BCRP; PI3K; Antibacterial	Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Brevianamide F (Cyclo(L-Pro-L-Trp)) 是一种从Colletotrichum gloeosporioides 中分离得到的真菌毒素，属于天然存在的 2,5-二酮哌嗪类，具有抗菌活性。它具有PI3Kα抑制活性，IC50值为 4.8 µM。
T21344	1-Deoxynojirimycin hydrochloride Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K; Antibacterial; Antibiotic; Glucosidase	Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling
	1-Deoxynojirimycin hydrochloride (Moranoline) 是一种口服有效的 α-葡萄糖苷酶抑制剂，具有降血糖、减肥和抗病毒的作用，可抑制餐后血糖，预防糖尿病。
T4S1499	Ginsenoside Rk1 人参皂苷RK1,人参皂苷	Apoptosis; Others; NF-κB; PI3K; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; Others; PI3K/Akt/mTOR signaling; Stem Cells
	Ginsenoside Rk1 是人参的高温加工提取物，抑制Jak2/Stat3信号通路和NF-κB 的激活。它具有抗肿瘤、抗血小板聚集活性、抗炎、抗胰岛素抵抗、肾保护和抗菌作用，可使认知功能增强，脂质积聚减少和预防骨质疏松症，还诱导细胞凋亡。
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine	PI3K	PI3K/Akt/mTOR signaling
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分，具有抗糖尿病、抗糖尿病肾病的作用。
T73812	Phosphatidylinositol 4,5-bisphosphate	Others	Others
	Phosphatidylinositol 4,5-bisphosphate（L-alpha-Phosphatidylinositol-4,5-bisphosphate）为细胞膜磷脂成分，主要作为磷脂酶C（PLC）与磷酸肌醇3-激酶（PI3K）的底物，充当重要信使。
TN5050	Sprengerinin C	NADPH-oxidase; VEGFR; p38 MAPK; ROS; Akt; PI3K; mTOR; p53	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein endothelial cells, it blocks vascul

天然产物

Heterophyllin B

Cat.No: T4S1796

Target: PI3K

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Cat.No: TN1134

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

Cat.No: T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

(+)-Nortrachelogenin

Cat.No: TN4673

Synonym: Wikstromol,荛花酚

Target: Apoptosis, HIV Protease, PI3K, Antifection

Cat.No: T5654

Target: Others

Quercetin Dihydrate

Cat.No: T6630

Synonym: 槲皮素,Sophoretin

Target: Apoptosis, PI3K

Cat.No: T2174

Synonym: 槲皮素,Sophoretin

Target: Apoptosis, Mitophagy, Reactive Oxygen Species, PI3K, Autophagy

3-Methyladenine

Cat.No: T1879

Synonym: 3-MA,3-甲基腺嘌呤,NSC 66389

Target: Mitophagy, PI3K, Endogenous Metabolite, Autophagy

Cat.No: T2798

Synonym: 秦皮乙素,二羟基香豆素,Aesculetin,Cichorigenin

Target: Lipoxygenase, Akt, PI3K

Sophocarpine monohydrate

Cat.No: T2746

Synonym: 槐果碱,Sophocarpine,槐果碱水合物

Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy

Glaucocalyxin A

Cat.No: T4S0498

Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Cat.No: TN2019

Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

Target: BCL, Caspase, PI3K

Cat.No: TN1405

Synonym: 山金车内酯 D,山金车内酯D

Target: Akt, Caspase, PI3K, STAT, mTOR

Polygalasaponin F

Cat.No: T3826

Synonym: 异牡荆苷,瓜子金皂苷己

Target: NF-κB, TLR, Akt, PI3K

Cat.No: T3780

Synonym: Hypocretin-2,木蝴蝶苷B

Target: Apoptosis, PTEN, Antioxidant, PI3K, Autophagy

Desmethylglycitein

Cat.No: TN1299

Synonym: 4',6,7-三羟基异黄酮,4',6,7-三羟异黄酮,6-羟基大豆苷元,6,7,4'-Trihydroxyisoflavone

Target: PI3K, CDK, PKC

Cat.No: T4867

Synonym: Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

Target: PI3K, Endogenous Metabolite

25(R,S)-Ruscogenin

Cat.No: T5740

Synonym: (25RS)鲁斯可皂苷元,(25RS)-Ruscogenin

Target: Others, HIF

Hederacolchiside A1

Cat.No: T2P2806

Synonym: 黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

1-Deoxynojirimycin

Cat.No: T3675

Synonym: Duvoglustat,Moranoline,1-脱氧野尻霉素,moranolin

Target: PI3K, Glucosidase

α-Linolenic acid

Cat.No: T3P2904

Synonym: Alpha-Linolenic Acid,Linolenic acid,α-亚麻酸

Target: Akt, PI3K

1,3-Dicaffeoylquinic acid

Cat.No: T5736

Synonym: CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Target: Reactive Oxygen Species, Akt, PI3K

Dihydrocapsaicin

Cat.No: T2163

Synonym: CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

Cat.No: T3208

Synonym: Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)

Target: BCRP, PI3K, Antibacterial

1-Deoxynojirimycin hydrochloride

Cat.No: T21344

Synonym: Moranoline,去氧野艽霉素盐酸盐,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin

Target: PI3K, Antibacterial, Antibiotic, Glucosidase

Ginsenoside Rk1

Cat.No: T4S1499

Synonym: 人参皂苷RK1,人参皂苷

Target: Apoptosis, Others, NF-κB, PI3K, JAK

(2S,3R,4S)-4-Hydroxyisoleucine

Cat.No: T2P2919

Synonym: (4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine

Target: PI3K

Phosphatidylinositol 4,5-bisphosphate

Cat.No: T73812

Target: Others

Cat.No: TN5050

Target: NADPH-oxidase, VEGFR, p38 MAPK, ROS, Akt, PI3K, mTOR, p53

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04933	PIK3IP1 Protein, Mouse, Recombinant (His) 5830455E04Rik,Hgfl,1500004A08Rik,Crkd,phosphoin...	Mouse	HEK293 Cells
	PIK3IP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.5 kDa and the accession number is Q7TMJ8-1.
TMPY-03111	PIK3IP1 Protein, Human, Recombinant (hFc) phosphoinositide-3-kinase interac...	Human	HEK293 Cells
	PIK3IP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is AAH11049.1.
TMPH-01857	PIK3CG Protein, Human, Recombinant (His & Myc) p120-PI3K,Phosphoinositide-3-...	Human	E. coli
	PIK3CG Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.4 kDa and the accession number is P48736.
TMPJ-01271	PIK3IP1 Protein, Human, Recombinant (His) Kringle domain-containing protein HGFL,PIK3IP1,HGFL	Human	HEK293 Cells
	Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibrom...
TMPY-06986	FGF-8b Protein, Human, Recombinant NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132	Mesothelin Protein, Human, Recombinant MPF,SMRP,Mesothelin	Human	HEK293 Cells
	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His) MER6,CD47 molecule,IAP,OA3	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc) Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated CD47 molecule,MER6,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-04683	CD47 Protein, Human, Recombinant MER6,CD47 molecule,OA3,IAP	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His) NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His) PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His) PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...	Human	HEK293 Cells
	Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His) L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-01180	CD86 Protein, Human, Recombinant (His) CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His) HNT,NTRI,IGLON2,neurotrimin	Human	HEK293 Cells
	HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-04298	CDCP1 Protein, Human, Recombinant (His) TRASK,CD318,CUB domain containing protein 1,SIMA1	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00480	NCAM1 Protein, Human, Recombinant (His) neural cell adhesion molecule 1,CD56,MSK39,NCAM	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-03621	EphB2 Protein, Mouse, Recombinant (hFc) Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST) SET and MYND domain containing 3,ZMYND1,KMT3	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03149	CDCP1 Protein, Human, Recombinant (mFc) TRASK,SIMA135,CD318,CUB domain containing ...	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc) CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPJ-01288	KLF6 Protein, Human, Recombinant CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-00276	PLGF/PGF Protein, Human, Recombinant (mFc) placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2	Human	HEK293 Cells
	PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-04015	COL9A1 Protein, Human, Recombinant (mFc) DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPY-06411	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated CD357,GITR-D,tumor necrosis factor receptor superfa...	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-05514	RANK/TNFRSF11A Protein, Human, Recombinant (mFc) OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-03960	COL9A1 Protein, Human, Recombinant (His) EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...	Human	HEK293 Cells
	COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPK-00398	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Fibroblast growth factor receptor 2,CD332,...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00401	FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...	Human	HEK293 Cells
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPJ-00391	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-04216	EphB2 Protein, Mouse, Recombinant (His) Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPY-00715	CD84 Protein, Human, Recombinant (His) LY9B,mCD84,CD84 molecule,hCD84,SLAMF5	Human	HEK293 Cells
	CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3.
TMPY-03883	CD47 Protein, Human, Recombinant (hFc) OA3,CD47 molecule,IAP,MER6	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-02573	IL-17RC Protein, Human, Recombinant (aa 1-454, His) IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR...	Human	Baculovirus Insect Cells
	IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-01656	VEGF183 Protein, Human, Recombinant 血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...	Human	Baculovirus Insect Cells
	VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-03969	SUSD4 Protein, Human, Recombinant (mFc) sushi domain containing 4,PRO222	Human	HEK293 Cells
	SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPJ-00465	PTP1C Protein, Human, Recombinant (His) HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,...	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPY-01692	NETO1 Protein, Human, Recombinant (His) neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1	Human	HEK293 Cells
	Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr...
TMPY-03705	VEGF164 Protein, Canine, Recombinant 血管内皮生长因子,vascular endothelial growth factor A	Canine	HEK293 Cells
	VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-05590	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated NCAM,MSK39,CD56,neural cell adhesion molecule 1	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPY-04157	RANK/TNFRSF11A Protein, Human, Recombinant (His) ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe...	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00729	Siglec-6 Protein, Human, Recombinant (His & Avi) SIGLEC6,OBBP1,CD327,CD33L1,CD...	Human	HEK293 Cells
	Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
TMPK-00400	FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.
TMPJ-00390	FGFR2IIIb Protein, Human, Recombinant (hFc) FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b...	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
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重组蛋白

PIK3IP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04933

Species: Mouse

Expression System: HEK293 Cells

PIK3IP1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03111

Species: Human

Expression System: HEK293 Cells

PIK3CG Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01857

Species: Human

Expression System: E. coli

PIK3IP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01271

Species: Human

Expression System: HEK293 Cells

FGF-8b Protein, Human, Recombinant

Cat.No: TMPY-06986

Species: Human

Expression System: E. coli

Mesothelin Protein, Human, Recombinant

Cat.No: TMPY-00132

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (aa 1-139, His)

Cat.No: TMPY-04935

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03763

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05191

Species: Human

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00072

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant

Cat.No: TMPY-04683

Species: Human

Expression System: HEK293 Cells

Neuropilin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00892

Species: Human

Expression System: HEK293 Cells

PRSS3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01897

Species: Human

Expression System: HEK293 Cells

Periostin/OSF-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01020

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04142

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Human, Recombinant (aa 26-577, His)

Cat.No: TMPY-05748

Species: Human

Expression System: HEK293 Cells

CD86 Protein, Human, Recombinant (His)

Cat.No: TMPY-01180

Species: Human

Expression System: HEK293 Cells

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-01099

Species: Human

Expression System: HEK293 Cells

HNT/NTM Protein, Human, Recombinant (His)

Cat.No: TMPY-00357

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04298

Species: Human

Expression System: HEK293 Cells

NCAM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00480

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03621

Species: Mouse

Expression System: HEK293 Cells

SMYD3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01268

Species: Human

Expression System: Baculovirus Insect Cells

CDCP1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03149

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

Cat.No: TMPY-04386

Species: Human

Expression System: Baculovirus Insect Cells

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

Cat.No: TMPK-00447

Species: Human

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

Cat.No: TMPJ-01288

Species: Human

Expression System: E. coli

PLGF/PGF Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00276

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04015

Species: Human

Expression System: HEK293 Cells

GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06411

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

Cat.No: TMPY-05514

Species: Human

Expression System: HEK293 Cells

COL9A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03960

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Cat.No: TMPK-00398

Species: Human

Expression System: HEK293 Cells

FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00401

Species: Human

Expression System: HEK293 Cells

FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

Cat.No: TMPJ-00391

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04216

Species: Mouse

Expression System: HEK293 Cells

CD84 Protein, Human, Recombinant (His)

Cat.No: TMPY-00715

Species: Human

Expression System: HEK293 Cells

CD47 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03883

Species: Human

Expression System: HEK293 Cells

IL-17RC Protein, Human, Recombinant (aa 1-454, His)

Cat.No: TMPY-02573

Species: Human

Expression System: Baculovirus Insect Cells

VEGF183 Protein, Human, Recombinant

Cat.No: TMPY-01656

Species: Human

Expression System: Baculovirus Insect Cells

SUSD4 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03969

Species: Human

Expression System: HEK293 Cells

PTP1C Protein, Human, Recombinant (His)

Cat.No: TMPJ-00465

Species: Human

Expression System: E. coli

NETO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01692

Species: Human

Expression System: HEK293 Cells

VEGF164 Protein, Canine, Recombinant

Cat.No: TMPY-03705

Species: Canine

Expression System: HEK293 Cells

NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05590

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (His)

Cat.No: TMPY-04157

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPK-00399

Species: Human

Expression System: HEK293 Cells

Siglec-6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00729

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00400

Species: Human

Expression System: HEK293 Cells

FGFR2IIIb Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00390

Species: Human

Expression System: HEK293 Cells

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