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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15118 |
DiD perchlorate
|
Others | Others |
DiD perchlorate 是一种远红色荧光亲脂性花青染料。它能快速稳定地与磷脂细胞膜结合,能用于细胞追踪。 | |||
T10066 |
2',5'-Dideoxyadenosine
|
Adenylyl cyclase; Adrenergic Receptor; AChR | GPCR/G Protein; Neuroscience |
2',5'-Dideoxyadenosine 是一种非竞争性腺苷酸环化酶抑制剂,通过结合 P 位点,IC50为 3 µM。它是核苷类似物,在心脏中发挥强大的抗肾上腺素作用。 | |||
T27594 |
Ilmetropium iodide
|
Others | Others |
Ilmetropium iodide 是一种支气管扩张剂。 | |||
T19807 |
Dithiazanine iodide
Delvex,Telmide,Vercidon,Abminthic,Netocyd,NSC 221154 |
Others | Others |
Dithiazanine iodide (Netocyd) 是一种苯并噻唑。它已被用作抗虫剂。它作为纳米颗粒在治疗胶质母细胞瘤方面也很有效。 | |||
T11039 |
Didesethyl chloroquine
Bisdesethylchloroquine |
Drug Metabolite | Metabolism |
Didesethyl chloroquine (Bisdesethylchloroquine) 是一种有效的心肌抑制剂。Didesethyl chloroquine 是抗疟药氯喹的主要代谢产物。 | |||
T60091 |
Sodium iodide
|
Others | Others |
Sodium iodide 是一种可口服且具有放射性的化合物,可用于预防断奶前奶牛呼吸系统疾病。 | |||
T22604 |
(-)-Bicuculline methiodide
|
Others | Others |
(-)-Bicuculline methiodide is a GABAA receptor antagonist. | |||
T60128 |
N,N-Didesethyl Sunitinib Hydrochloride
|
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
N,N-Didesethyl Sunitinib Hydrochloride 是一种有效的AMPK 抑制剂,对AMPKα1和AMPK2的IC50分别为393nM 和141nM。 | |||
T50058 |
1-(cyclohexylmethyl)guanidine hydroiodide
|
Others | Others |
1-(cyclohexylmethyl)guanidine hydroiodide 是一种胍衍生物,已被用作合成多种化合物的试剂,包括肽、拟肽和其他生物活性分子,也被用作合成其他催化剂,如酰胺、酯和醚。 | |||
T18975 |
DIDS sodium salt
4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠[蛋白质改性试剂],MDL101114ZA |
VDAC; ABC | Membrane transporter/Ion channel |
DIDS sodium salt (MDL101114ZA) 是有效的ABCA1和VDAC1双抑制剂。 | |||
T50003 |
Debrisoquin hydriodide
1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide |
Others | Others |
Debrisoquin hydriodide (1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide) 具有抗氧化、抗炎和神经保护特性,也被发现可以调节某些神经递质的活性,包括多巴胺和血清素,使其成为治疗帕金森病和抑郁症等神经疾病的有前途的候选药物。 | |||
TNU0839 |
1,4-Dideoxy-1,4-epithio-D-ribitol
|
Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
1,4-Dideoxy-1,4-epithio-D-ribitol 是一种靶向惰性淋巴系统恶性肿瘤的嘌呤核苷类似物,具有广泛的抗肿瘤活性。1,4-Dideoxy-1,4-epithio-D-ribitol 通过抑制 DNA 合成诱导细胞凋亡 (apoptosis) 。 | |||
T9169 |
MPP+ iodide
|
Mitochondrial Metabolism; Autophagy | Autophagy; Metabolism |
MPP+ iodide 是一种神经毒素 MPTP 的有毒代谢物,也是一种 5-羟色胺转运体 (SERT) 的高亲和力底物。MPP+ iodide 对多巴胺能神经元有毒,可以在动物模型中导致帕金森症。 | |||
T0357 |
Potassium iodide
|
Tyrosinase | Proteases/Proteasome |
Potassium iodide 用于治疗过度活跃的甲状腺,并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。 | |||
T5051 |
Isopropamide Iodide
|
AChR | Neuroscience |
Isopropamide iodide 是长效季铵盐抗胆碱能药物。它用于研究消化性溃疡和其他胃肠道疾病,尤其是胃酸过多和运动过度。 | |||
T60191 |
Cuprous iodide
Iodocopper,Copper (I) iodide |
Antibiotic | Microbiology/Virology |
Cuprous iodide (Iodocopper) 是一种抗菌化合物。 | |||
T0720 |
Gallamine triethiodide
加拉碘铵,Benzkurin,三碘季胺酚,Flaxedil |
AChR | Neuroscience |
Gallamine triethiodide (Benzkurin) 是胆碱能受体合成抑制剂和非去极化阻断剂,IC50为68.0±8.4 μM。它是合成抑制药物,具有非去极化作用。 | |||
T7525 |
Didox
3,4-二羟基苯甲羟肟酸,NSC-324360 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Didox (NSC-324360) 是一种合成的核糖核苷酸还原酶抑制剂,可降低患有痴呆症的 HIV 患者大脑中氧化损伤标志物的水平。 | |||
T5949 |
Dideoxyadenosine
|
Others | Others |
2',3'-Dideoxyadenosine 是HIV 复制抑制剂,具有抗逆转录病毒活性和抗病毒的作用[1]。 | |||
T12339 |
Oxotremorine M iodide
碘化氧化震颤素M,Oxotremorine methiodide |
AChR | Neuroscience |
Oxotremorine M iodide (Oxotremorine methiodide) 是 mAChR 的激动剂,可增强 NMDA 受体。 | |||
T20974 |
IR-780 Iodide
IR 780 iodide,IR-780 碘化物 |
Others | Others |
IR-780 Iodide (IR 780 iodide) 是一种近红外荧光染料,用于通过 HIF-1α/糖酵解依赖性线粒体转运蛋白 ABCB10 的活性对人类 CSC 进行独特的表征。 | |||
T2578 |
Didanosine
ddI,去羟肌苷,2',3'-Dideoxyinosine |
HIV Protease; Reverse Transcriptase | Microbiology/Virology; Proteases/Proteasome |
Didanosine (ddI) 是一种逆转录酶抑制剂,IC50为490nM。 | |||
T2130 |
Propidium Iodide
PI,碘化丙啶,碘化丙啶(PI) |
Others | Others |
Propidium Iodide (PI) 是一种可用于细胞染色的红色荧光染料,适用于荧光显微镜、共聚焦显微镜、流式细胞仪以及荧光计分析。在水溶液中,Propidium Iodide 的 Ex/Em 为 493/636 nm;与核酸结合后,PI-核酸的 Ex/Em 变为 535/617 nm,同时荧光信号增强 20-30 倍。 | |||
TD0085 |
DiR iodide
DiR iodide [1,1‘-dioctadecyl-3,3,3’,3‘-tetramethylindotricarbocyanine iodide],DiR细胞膜荧光探针,DiR碘化物 |
Others | Others |
DiR iodide (DiR iodide [1,1‘-dioctadecyl-3,3,3’,3‘-tetramethylindotricarbocyanine iodide]) 是一种重要的近红外 (NIR) 荧光染料,已广泛用于细胞的体内监测。 | |||
T60222 |
3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide
|
Others | Others |
3-(2,6-dichlorobenzyl)-1-hexadecyl-2-methyl-1H-imidazol-3-ium iodide 是果糖1,6-二磷酸醛缩酶的有效抑制剂。 | |||
T4949 |
1,2-Didecanoyl-sn-glycero-3-phosphocholi
1,2-Didecanoyl Phosphatidylcholine,1,2-Didecanoyl PC,L-A-癸酰磷脂酰胆碱 |
Others | Others |
1,2-Didecanoyl-sn-glycero-3-phosphocholi (1,2-Didecanoyl PC) 是一种合成的、疏水性较低的磷脂,已被发现可用于增强肽类药物和激素(如胰岛素)的吸收。 | |||
T15117 |
Didesmethyl cariprazine
|
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Didesmethyl cariprazine 是 Cariprazine 的代谢物,是主要的循环活性部分。 Didesmethyl cariprazine 有较长的半衰期,为 1-3 周。Cariprazine 是一种有效的多巴胺D3偏好D3/D2受体部分激动剂,用于治疗精神分裂症、双相躁狂和抑郁症,对d3和d2受体具有高亲和力,对5-HT 1A 受体具有中等亲和力。 | |||
T34146 |
Propanidid
FBA 1420,Epontol,Sombrevin,Fabontal,Fabantol |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Propanidid (Sombrevin) 是一种 γ-氨基丁酸 A 型受体 (GABAA) 激动剂,也是一种可快速发挥作用的静脉注射麻醉剂,可以降低动脉血压。 | |||
T62996 |
10-Formyl-5,8-dideazafolic acid
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
10-Formyl-5,8-dideazafolic acid 是 10-甲酰基四氢叶酸脱氢酶的底物,是胸苷酸合成酶抑制剂。 | |||
T18557 | Pomalidomide-PEG6-butyl iodide | Others | Others |
Pomalidomide-PEG6-butyl iodide is a chemically synthesized conjugate compound that functions as an E3 ligase ligand-linker conjugate. It combines the cereblon ligand derived from Pomalidomide with a 6-unit PEG linker, which is commonly utilized in PROTAC technology[1]. | |||
T22404 |
Pralidoxime Iodide
2-PAM,碘解磷定 |
Others | Others |
Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning. | |||
T22659 |
Chlorisondamine diiodide
|
Others | Others |
long lasting nicotinic antagonist | |||
T23034 |
Muscarine iodide
(+)-Muscarine iodide |
Others | Others |
Muscarinic acetylcholine receptor agonist | |||
TP1684 |
Ac-IEVDIDVEH (TFA)
|
||
Ac-IEVDIDVEH TFA is a short peptide sequence with Ac at the end. | |||
TP1642 |
Ac-VDID (TFA)
|
||
Ac-VDID TFA is a short peptide sequence with Ac at the end. | |||
T30012 |
Ammonium, (4-(p-ethyldimethylammoniophenyl)butyl)ethyldimethyl-, diiodide
|
Others | Others |
Ammonium, (4-(p-ethyldimethylammoniophenyl)butyl)ethyldimethyl-, diiodide 可用于生命科学领域的相关研究。其产品编号为 T30012,CAS号为 63981-94-2。 | |||
TNU1289 |
1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil
|
Others | Others |
1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside. | |||
T65263 |
JC-1 iodide
|
Others | Others |
JC-1 iodide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65263。 | |||
T36750 |
Didesmethylrocaglamide
|
Others | Others |
Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting signaling pathways and triggers apoptosis in tumor cells, demonstrating antitumor activity[1]. | |||
T33140 |
m-Acetanisidide, 2-chloro-N-(2-ethoxyethyl)-
|
Others | Others |
m-Acetanisidide, 2-chloro-N-(2-ethoxyethyl)- is a bioactive chemical. | |||
T131532 |
Laureline ethiodide
|
Others | Others |
Laureline ethiodide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131532。 | |||
T32115 |
Hydrogenated didecene
1-Decene,dimers,Dec-1-ene,hydrogenated,dimer |
Others | Others |
Hydrogenated didecene as skin-softening agent derived from didecene, which is a hydrocarbon. Hydrocarbons are organic compounds that contain only carbon and hydrogen. Examples of common hydrocarbons include mineral oil, petroleum, and paraffin wax. | |||
T69373 |
Pyrvinium Iodide
|
Others | Others |
Pyrvinium Iodide is a casein kinase 1α-dependent inhibitor of Wnt/β-Catenin. | |||
T30008 |
Ammonium, ((p-triethylammonio)phenethyl)triethyl-, diiodide
|
Others | Others |
Ammonium, ((p-triethylammonio)phenethyl)triethyl-, diiodide is a bioactive chemical. | |||
T30999 |
Colchicine, deacetamido-5,6-didehydro-
Deacetamido-6-dehydrocolchicine,Colchicine,deacetamido-6-dehydro- (7CI) |
Others | Others |
Colchicine, deacetamido-5,6-didehydro- is a biochemical. | |||
T60371 |
7-Deaza-2',3'-dideoxyguanosine
|
Others | Others |
7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) 是一种 2',3'-dideoxynucleoside 5'-triphosphate,抑制HIV-1逆转录酶,Ki 值为 25 nM。 | |||
T71072 |
Hexbutinol methiodide
|
Others | Others |
Hexbutinol methiodide is an inhibitor of muscarinic receptors. | |||
TNU0929 |
2’,3’-Dideoxy-3’-fluorouridine
|
Others | Others |
Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; Anti-HIV agent | |||
T33150 |
m-Acetotoluidide, 2-fluoro-N-methyl-
|
Others | Others |
m-Acetotoluidide, 2-fluoro-N-methyl- is a bioactive chemical. | |||
T31439 |
Didesacetylphyllanthostatin 3
Ddapt3,Ddapt 3,Ddapt-3 |
Others | Others |
Didesacetylphyllanthostatin 3 is a biochemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T25327 |
Didemnin B
NSC 325319,NSC325319,膜海鞘素B,NSC-325319,Didemnin-B |
Antiviral | Immunology/Inflammation |
Didemnin B (Didemnin-B) 是一种从海洋金枪鱼 Tridemnin cyanophorum 中提取的脱脂肽,具有抗病毒和抗肿瘤活性。 | |||
T6751 |
Acetylcholine iodide
Acetylcolina |
Others | Others |
Acetylcholine iodide (Acetylcolina) 是一种在中枢和外周神经系统中常见的神经递质。 | |||
T3787 |
Didymin
Isosakuranetin-7-O-rutinoside,Neoponcirin,香风草甙 |
Apoptosis; Others | Apoptosis; Others |
Didymin (Neoponcirin) 从柑橘类水果中提取的一种膳食类黄酮苷,具有抗氧化特性。它通过抑制 N-Myc 和上调 RKIP 诱导凋亡。 | |||
TQ0185 |
14-Deoxy-11,12-didehydroandrographolide
AP10,14-脱氧-11,12-二去氢穿心莲内酯,14-dehydro Andrographolide |
NF-κB | NF-κB |
14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物,能够抑制 NF-κB 活性。 | |||
T3S1320 |
(+)-Magnoflorine iodide
Magnoflorine iodide,Thalictrine iodide,碘化木兰花碱,Corytuberine Methiodide |
Others; Antifungal | Microbiology/Virology; Others |
(+)-Magnoflorine iodide (Thalictrine iodide) 是从 Acoruscalamus 中分到的一种阿朴啡生物碱,具有抗炎、抗真菌、抗氧化和抗糖尿病的作用,可以减少C. albicans 生物膜的形成。 | |||
TN2622 | 14-Deoxy-11,12-didehydroandrographiside | Others | Others |
14-Deoxy-11,12-didehydroandrographiside是一种天然产物,属于爵床科穿心莲属,其产品编号为 TN2622,CAS号为 141973-41-3。14-Deoxy-11,12-didehydroandrographiside可用作对照参考。 | |||
TN5712 |
9,10-Didehydroeffususol A
5-(1-Methoxyethyl)-1-methylphenanthrene-2,7-diol |
||
9,10-Didehydroeffususol A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5712,CAS号为 1869082-57-4。 | |||
T83394 |
25-O-acetyl-7,8-didehydro-cimigenol-3-O-b-Dxylopyaranoside
|
||
25-O-acetyl-7,8-didehydro-cimigenol-3-O-β-D-xylopyranoside 是环阿烷三萜类化合物,可从 Cimicifuga acerina 分离得到。 | |||
TN3205 |
7,13-Dideacetyl-9,10-didebenzoyltaxchinin C
|
Others | Others |
7,13-Dideacetyl-9,10-didebenzoyltaxchinin C is a natural product from Taxus chinensis var. mairei. | |||
T82562 |
Dide-O-methylgrandisin
|
||
Dide-O-methylgrandisin 为一类二芳基四氢呋喃型化合物。 | |||
T83371 |
3,4-Didehydroglabridin
|
||
3,4-Didehydroglabridin 是甘草中的天然产物,具有对四氯化碳诱导的 HepG2 细胞损伤的保护作用,展现出在肝损伤研究中的应用潜力。 | |||
TN7444 |
24-epi-7,8-Didehydrocimigenol 3-xyloside
|
Others | Others |
TN2742 |
2,7-Dideacetoxytaxinine J
|
Others | Others |
2,7-Dideacetoxytaxinine J 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2742,CAS号为 115810-14-5。 | |||
TN2649 |
16-O-Methyl-14,15-didehydroisovincanol
|
Others | Others |
16-O-Methyl-14,15-didehydroisovincanol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2649,CAS号为 112237-71-5。 | |||
TN2620 |
14,15-Didehydrovincamenine
|
Others | Others |
14,15-Didehydrovincamenine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2620,CAS号为 112219-48-4。 | |||
TN3269 |
8,9-Didehydro-7-hydroxydolichodial
|
Others | Others |
8,9-Didehydro-7-hydroxydolichodial是一种天然产物,属于败酱科败酱属,其产品编号为 TN3269,CAS号为 97856-19-4。8,9-Didehydro-7-hydroxydolichodial可用作对照参考。 | |||
TN3219 |
7,8-Didehydrocimigenol
|
ERK; IκB/IKK; TNF; NF-κB; Akt; PPAR | Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling |
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression. | |||
T74497 |
S-Adenosyl-L-methionine iodide
|
Others | Others |
S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) 是所有生物体中重要的甲基供体。 | |||
T21126 |
Didecyl ether
Capric ether,Di-n-decyl ether,Decane, 1,1'-oxybis-,1,1'-Oxybisdecane |
||
Didecyl ether is a biochemical. | |||
TN1286 |
5,6-Didehydroginsenoside Rd
5,6-Dehydroginsenoside Rd,5,6-二去氢人参皂苷 RD,5,6-脱氢人参皂苷Rd |
Others | Others |
5,6-Dehydroginsenoside Rd is a natural product | |||
T83329 |
4,7-Didehydroneophysalin B
|
||
4,7-Didehydroneophysalin B,一种源自Physalis alkekengi L. var. franchetii (Mast.) Makino的黄酮类化合物,展现出胆碱酯酶的抑制作用。 | |||
TN1205 |
2,3-Didehydrosomnifericin
|
Others | Others |
2,3-Didehydrosomnifericin is a natural product | |||
TN3844 |
Didrovaltrate
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Didrovaltrate shows cytotoxic against human cancer cell lines. Didrovaltrate blocks I(Ca-L) in a concentration-dependent manner and probably inhibits I(Ca-L) in its inactive state, which may contribute to its cardiovascular effect. | |||
T5S0636 |
Citric acid
柠檬酸,Citro,Citretten |
Apoptosis; Others; Endogenous Metabolite; Antibacterial; Antibiotic | Apoptosis; Metabolism; Microbiology/Virology; Others |
Citric acid (Citro) 是柑橘类水果中发现的弱有机三羧酸。柠檬酸是食品添加剂和天然防腐剂。 | |||
T2S0850 |
Malic acid
E 296,苹果酸,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid |
Others; Endogenous Metabolite | Metabolism; Others |
Malic acid (Pomalus acid) 是一种天然存在于水果中的二羧酸,如苹果和梨。Malic acid 在许多酸味或酸味食物中起作用。 | |||
T5S0994 |
N-Methylcytisine
N-甲基野靛碱,Caulophylline |
Others; AChR | Neuroscience; Others |
N-Methylcytisine (Caulophylline) 是苦参中的一种三环喹啉类生物碱,具有降血糖、缓解疼痛和抗炎活性。它是中枢神经系统中乙酰胆碱烟碱受体的选择性配体,对鱿鱼视神经节中的烟碱乙酰胆碱受体具有很高的亲和力,Kd 为 50 nM。 | |||
TN3049 |
4-Methoxycinnamyl alcohol
|
Others | Others |
4-Methoxycinnamyl alcohol 对MCF-7、HeLa 和DU145癌症细胞系显示出毒性,IC50值分别为14.24、7.82和22.10μg/mL。4-methoxycinnamyl alcohol 是从Foeniculum vulgare 中分离出来的。4-Methoxycinnamyl alcohol 没有显示出凋亡作用,却在10μg/mL DNA 碎片研究显示48小时后发生了坏死。 | |||
T28379 |
PF-1163B
PF1163B,(-)-PF1163B,PF 1163B |
Others | Others |
PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotox | |||
TN1766 |
(-)-Integerrimine
Integerrimine,全緣千里光鹼,全缘千里光碱 |
Others | Others |
Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects. | |||
TN5447 |
Apigenin 7-O-methylglucuronide
芹菜素-7-O-β-D-葡萄糖醛酸甲酯,Apigenin-7-O-β-D-glucuronide methyl ester |
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Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide which normalized collagen synthesis in |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00336 |
GPD2 Protein, Candida albicans, Recombinant (His)
GPD2,Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 |
Candida albicans | P. pastoris (Yeast) |
GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is Q59W33. | |||
TMPH-00332 |
Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His)
Aspartate protease 2,ACP 2,Secreted aspartic protease 2,Can<... |
Candida albicans | E. coli |
Candidapepsin-2 Protein, Candida albicans (strain WO-1), Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is C4YMJ3. | |||
TMPH-00334 |
Candidapepsin-6 Protein, Candida albicans, Recombinant (His)
SAP6,Candidapepsin-6,Secreted aspartic protease 6,A... |
Candida albicans | E. coli |
Candidapepsin-6 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.8 kDa and the accession number is P43095. | |||
TMPH-00339 |
Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His)
ACC1 |
Candida glabrata | E. coli |
Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.2 kDa and the accession number is A0A0W0CTK3. | |||
TMPH-00333 |
Candidapepsin-2 Protein, Candida albicans, Recombinant (His)
Candidapepsin-2,Aspartate protease 2,SAP2,PRA2,Secr... |
Candida albicans | E. coli |
Candidapepsin-2 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P0CS83. | |||
TMPH-00338 |
PRA1 Protein, Candida albicans, Recombinant (His)
58 kDa fibrinogen-binding mannoprotein,PRA1,pH-regulated ant... |
Candida albicans | P. pastoris (Yeast) |
PRA1 Protein, Candida albicans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.4 kDa and the accession number is P87020. | |||
TMPH-00330 |
Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His)
ACC1 |
Candida albicans | E. coli |
Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1D8PRR7. | |||
TMPH-00340 |
ATG1 Protein, Candida glabrata, Recombinant (His)
Autophagy-related protein 1,Serine/threonine-protein kinase ... |
Candida glabrata | E. coli |
ATG1 Protein, Candida glabrata, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.4 kDa and the accession number is Q6FL58. | |||
TMPH-00331 |
ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc)
Adhesin 3,3D9 antigen,Agglutinin-like protein 3 |
Candida albicans | E. coli |
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. ALS3 Prot... | |||
TMPH-00337 |
HWP1 Protein, Candida albicans, Recombinant (His)
Hyphal wall protein 1,HWP1,Cell elongation protein 2 |
Candida albicans | E. coli |
HWP1 Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is P46593. | |||
TMPH-00335 |
FBA1 Protein, Candida albicans, Recombinant (His & Myc)
Fructose-1,6-bisphosphate aldolase,IgE-binding allergen,Fruc... |
Candida albicans | E. coli |
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. FBA1 Protein, Candida albicans, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9URB4. | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-00105 |
Recombinant Protein G
|
E. coli | |
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... | |||
TMPY-02686 |
PON3 Protein, Human, Recombinant (S50N, His)
paraoxonase 3 |
Human | Baculovirus Insect Cells |
PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expression of inflammatory genes. PON3 deficiency did not influence atherosclerosis development on an apolipoprotein E null hyperlipidemic background, but it did lead to a significant 60% increase in atherosclerotic lesion size in Pon3KO mice on the C57BL/6J background when fed a cholate... | |||
TMPK-00842 |
CD21 Protein, Human, Recombinant (His)
CD21,CR2,C3DRSLEB9,EBV receptor,CVID7,SLEB9,C3DR |
Human | HEK293 Cells |
CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 protein expression was also transiently transferred to NK cells after co-culture with an EBV-positive Burkitt lymphoma cell line (Raji) via trogocytosis. However, EBV did not infect NK cells through CD21-mediated trogocytosis. | |||
TMPK-01117 |
OSCAR Protein, Mouse, Recombinant (hFc)
PIgR-3,Poly-Ig receptor 3,OSCAR,MGC33613,mOSCAR,PIGR3 |
Mouse | HEK293 Cells |
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA. OSCAR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The p... | |||
TMPK-01057 |
CLEC9A Protein, Human, Recombinant (hFc)
CD370,UNQ9341,DNGR-1,HEEE9341,9830005G06Rik,CLEC9A |
Human | HEK293 Cells |
CLEC9A expression was significantly higher in psoriatic skin compared with healthy donor. In psoriatic skin and PsA ST, CLEC9A() cells were in close proximity to TUNEL() cells. SF CLEC9A levels were significantly lower compared with paired PsA serum. Adalimumab treatment did not affect CLEC9A serum level and skin expression. The downregulation of synovial CLEC9A might be associated with a novel mechanism by which anti-TNF therapy might reduce CD8-mediated inflammation in PsA patients. | |||
TMPY-03261 |
CNPY2 Protein, Human, Recombinant (His)
canopy FGF signaling regulator 2,HP10390,ZSIG9,MSAP,TMEM4 |
Human | HEK293 Cells |
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and... | |||
TMPK-01092 |
OSCAR Protein, Human, Recombinant (hFc)
Poly-Ig receptor 3,PIGR3,OSCAR,PIgR-3,MGC33613,mOSCAR |
Human | HEK293 Cells |
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA. OSCAR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The p... | |||
TMPY-04460 |
OXSR1 Protein, Human, Recombinant (GST)
OSR1,oxidative stress responsive 1 |
Human | Baculovirus Insect Cells |
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. OXSR1 is a 58 kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines. The amino acid (aa) sequence of the predicted OXSR1 protein is 39% identical to that of human SOK1. Of... | |||
TMPK-00090 |
NKp30/NCR3 Protein, Human, Recombinant (His & Avi)
NKp30,1C7,MALS,CD337,LY117,NCR3 |
Human | HEK293 Cells |
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature ph... | |||
TMPY-02499 |
Cofilin 2 Protein, Human, Recombinant (His)
cofilin 2 (muscle),NEM7 |
Human | E. coli |
Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparen... | |||
TMPJ-00629 |
TIGIT Protein, Cynomolgus, Recombinant (His)
VSTM3,V-set and transmembrane domain-containing protein 3,T-... |
Cynomolgus | HEK293 Cells |
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower... | |||
TMPY-03623 |
NKp80/KLRF1 Protein, Cynomolgus, Recombinant (hFc)
killer cell lectin like receptor F1,KLRF1 |
Cynomolgus | HEK293 Cells |
NKp80, also known as KLRF1, is an activating homodimeric C-type lectin-like receptor that is expressed on nearly all-natural killer cells and stimulates their cytotoxicity and cytokine release. NKp80 stimulates cytotoxicity upon engagement of its genetically linked ligand: myeloid-specific CTLR activation-induced C-type lectin (AICL). NKp80, but not NKp80 mutated at tyrosine 7 (NKp80/Y7F), is tyrosine phosphorylated. Accordingly, NKp80/Y7F, but not NKp80/Y3F or NKp80/Y37F, failed to induce cytot... | |||
TMPY-02549 |
GBP1 Protein, Human, Recombinant (His)
guanylate binding protein 1,GBP1 |
Human | HEK293 Cells |
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre... | |||
TMPY-04468 |
STK16 Protein, Human, Recombinant (His & NusA)
MPSK,serine/threonine kinase 16,TSF1,KRCT,PKL12 |
Human | E. coli |
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0234 |
Tiotropium Bromide EP Impurity G-d3 (Iodide)
|
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Tiotropium Bromide EP Impurity G-d3 (Iodide) 是 Tiotropium Bromide EP Impurity G (Iodide) 的氘代化合物。 | |||
TMIH-0339 |
Methyl-d3 Naltrexone Iodide
|
||
Methyl-d3 Naltrexone Iodide 是 Methyl Naltrexone Iodide 的氘代化合物。 |