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Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 169,800 | 2-4周 |
产品描述 | Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL). |
靶点活性 | A.fumigatus:2 μg/mL , Cryptococcus neoformans 451: 1 μg/mL , C.parapsilosis 937A: 8 μg/mL , Aspergillus niger 57A: 2 μg/mL , C. albicans 33/079:(MIC)1 μg/mL |
体外活性 | Amphotericin X1 (compound 4) shows antifungal activity combined with a pronounced reduction in hemolytic activity (EH50: 42 μg/mL) against mammalian erythrocytes in vitro. |
别名 | 两性霉素 X1 |
分子量 | 938.118 |
分子式 | C48H75NO17 |
CAS No. | 136135-57-4 |
密度 | 1.31 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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