18:0 lyso-pe

18:0 LYSO-PE是一种诱导[Ca2+]i增加的化合物，18:0 LYSO-PE可用作电喷雾质谱（ESI-MS） MS进行脂质分析的磷脂（PL）标准。

PE(10:0/10:0) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T66959。

(±)-2'-hydroxy Ceramide (d18:0 18:0)' 为一种鞘磷脂，能够自 ADP 刺激下的哺乳动物血小板中提取。

18:1 PEG-PE 是一种聚乙二醇/磷脂酰乙醇胺偶联物，可用于活性分子输送。

C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).

C18 Phytoceramide (t18:0 18:0) (Cer(t18:0 18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0 18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0 18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated murine skin tissue. Formulations containing cer(t18:0 18:0) have been used used in cosmetics as a skin protectants as they reduce water loss to prevent epidermal dehydration and irritation.

C18 L-erythro Ceramide (d18:1 18:0)可显著降低细胞外 Aβ 水平，可用于研究阿尔茨海默病。

18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) 是一种二酰基甘油，可以与RasGRP 结合并调节MAP 激酶活化。

C18 Ceramide-1-phosphate (d18:1 18:0) 是一种在鼠皮肤中发现的长链ceramide-1-phosphate。它能在0.5至5 µM的浓度范围内促进分离的小鼠骨髓来源的多能间充质细胞和人脐静脉内皮细胞（HUVECs）的迁移。与胰腺癌干细胞相比，CFPAC-1胰管腺癌细胞中C18 Ceramide-1-phosphate (d18:1 18:0)的水平有所增加。在Langendorff分离的灌流小鼠心脏的离体缺血模型中，心肌中C18 ceramide-1-phosphate (d18:1 18:0)的水平有所增加。

24:0 Lyso PC, a lysophospholipid (LyP), has potential applications in mRNA drug delivery.

C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. C18 globotriaosylceramide also accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease.

C26:0 Lyso PC-d9 是 C26:0 Lyso PC 的氘代化合物。C26:0 Lyso PC 的 CAS 号为 1213783-80-2。

PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂，是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生，但不增加 IFN-γ 的产生。 在小鼠血清中，PE(18:1(9Z)/0:0)（1 μg/动物）诱导 T 辅助细胞 2 反应。 在寒冷暴露三天后，小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。

C18 D-threoCeramide (d18:1 18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019) 2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidaseBiochemistry40(32)9657-9668(2001)

C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes. [2] It is also elevated in the skin of patients with lesional atopic dermatitis.[3]

C18 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. Levels of short-chain sulfatides, including C18 3'-sulfo galactosylceramide, decrease with age in mice and humans. It is increased in brain from mice with an arylsulfatase A deficiency (ASA-KO), particularly in lipid raft fractions. Plasma levels of C18 3'-sulfo galactosylceramide positively correlate with disability progression in patients with relapsing-remitting multiple sclerosis using the Expanded Disability Status Scale. It is also increased in plasma from patients with metachromatic leukodystrophy (MLD).

18:0 DAP 可用于制备脂质纳米粒 (LNPs)，mRNA 被包裹在其核心。

18:0 EPC chloride为合成阳离子磷脂，(在临界协同浓度2.34-2.93 μM)可显著增强丁香酚对大肠杆菌的灭活效能。

16:0-18:1 EPC chloride 是一种阳离子脂质，用于药物递送中的脂质体。

14: 0 PEG2000 PE (DMPE-PEG2000) 是一种聚乙二醇 （PEG）-磷脂偶联物，可在制备囊泡制剂时阻止囊泡聚集，可用于制备纳米结构脂质载体。