PROTAC ERα Degrader-1

Name: PROTAC ERα Degrader-1
Brand: TargetMol
SKU: T18636
Price: 496 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T18636

PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).

PROTAC ERα Degrader-1

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产品编号 T18636

规格	价格	库存	数量
100 mg	询价	期货
500 mg	询价	期货

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产品介绍

生物活性

产品描述	PROTAC ERα Degrader-1 is a chemical compound. It consists of a ubiquitin E3 ligase binding group, a linker, and a protein binding group. This compound serves as a degrader of estrogen receptor-alpha (ERα).
体外活性	Treatment of the HER2 expressing cells with the PROTAC ERα Degrader-1 (without Ab; compound P1) results in a decreased estrogen receptor-alpha (ERα) levels[1].

化学信息

分子量	1120.29
分子式	C₆₆H₆₉N₇O₁₀
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 200 mg/mL (178.53 mM), Sonication is recommended.

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	0.8926 mL	4.4631 mL	8.9263 mL	44.6313 mL
5 mM	0.1785 mL	0.8926 mL	1.7853 mL	8.9263 mL
10 mM	0.0893 mL	0.4463 mL	0.8926 mL	4.4631 mL
20 mM	0.0446 mL	0.2232 mL	0.4463 mL	2.2316 mL
50 mM	0.0179 mL	0.0893 mL	0.1785 mL	0.8926 mL
100 mM	0.0089 mL	0.0446 mL	0.0893 mL	0.4463 mL