TCO-PEG3-Biotin is a cleavable ADC linker comprised of three PEG units. It is primarily employed in the synthesis of ADCs, which are antibody-drug conjugates [1].
Biotin-PEG3-(CH2)3-NH2 TFA salt is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.