177
3
69
6
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22641 |
CDPPB
|
GluR | Neuroscience |
CDPPB 是选择性和脑渗透性的代谢型谷氨酸受体亚型5 (mGluR5) 阳性变构的调节剂,在表达人类 mGluR5 的中国仓鼠卵巢细胞中的 EC50值为 27 nM。它为开发抗精神病药提供了一种可能性。 | |||
T27172 |
Difamilast
|
PDE | Metabolism |
Difamilast 是局部的、选择性的非甾体磷酸二酯酶 4 抑制剂,对 B 亚型抑制作用较好 (IC50=11.2 nM)。它在研究轻度至中度特应性皮炎方面有研究的价值。 | |||
T15286 |
Flindokalner
BMS-204352 |
Potassium Channel | Membrane transporter/Ion channel |
Flindokalner (BMS-204352) 是一种钾离子通道调节剂。它是大电导钙激活 K 通道正向调节剂。它是在 HEK293 细胞中表达的所有神经元 Kv7通道亚型的正调节剂。它在 Kv7.1 通道 (Ki=3.7 μM) 处显示负调节活性,并充当 GABAA 受体的负调节剂。它在体内显示出抗焦虑功效。 | |||
T10539 |
BIBO3304 TFA
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
BIBO3304 TFA 是一种可口服的、选择性的神经肽 Y(NPY) Y1受体高效拮抗剂,对人和大鼠 Y1 受体均具有高亲和力,IC50分别为 0.38 和 0.72 nM。 | |||
T11394 |
GFB-8438
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
GFB-8438 是有效的TRPC5选择性抑制剂,对 hTRPC5 和 hTRPC4 的IC50分别为 0.18 和 0.29 μM。它对 TRPC6、其他 TRP 家族成员、NaV1.5 具有良好的选择性,对 hERG 通道的活性也有限。它对小鼠足细胞的保护作用。 | |||
T15795 |
Luzindole
N-乙酰-2-苄基色胺,N-0774 |
Melatonin Receptor; MT Receptor | GPCR/G Protein; Neuroscience |
Luzindole (N-0774) 是一种选择性褪黑素受体拮抗剂,可抑制实验性自身免疫性脑脊髓炎,有抗抑郁样活性。它优先靶向 MT2 (Mel1b),对于人 MT2 和 MT1 的 Ki 值分别为 10.2 和 158 nM。 | |||
T4993 |
Afloqualone
氟喹酮,HQ-495 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Afloqualone (HQ-495) 是一种 GABA 受体激动剂。靶点:体外 GABA 受体:Afloqualone 是一种喹唑啉酮家族 GABA 能药物。由于其在 GABAa 受体β亚型的激动剂活性,它具有镇静和肌肉松弛作用。 | |||
T13007 |
ST1936 oxalate
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
ST1936 oxalate 是一种 5-HT6 受体的选择性纳摩尔亲和激动剂,对人5-HT6、5-HT7和 5-HT2B 受体的 Ki 值分别为 13、168 和 245 nM。 | |||
T24381 |
L-822179
L822179,L 822,179,L 822179,L822,179,L-822,179 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
L-822179 (α5IA) 是 GABAA 受体 Α5 亚型的选择性反向激动剂,在 A5 亚型中具有比其他药物更高的内在活性。 | |||
T17144 |
TPA 023
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
TPA 023 是 GABAA α2/α3 亚型的特异性激动剂 (Ki = 0.19 - 0.41 nM)。 | |||
T9762 |
Upidosin
SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Upidosin (SB-216469) 是一种有效的、选择性的α1-肾上腺素受体拮抗剂,α1a 亚型Ki=0.34nM,α1b 亚型Ki=3.9nM,β1d 亚型Ki=1.5nM,γ2-肾上腺素受体Ki=33.3nM。 | |||
T20968 |
CyPPA
|
Potassium Channel; Dopamine Receptor | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
CyPPA 是hSK2和hSK3的阳性调节剂,其EC50值分别为 5.6 μM 和14 μM。它对 hSK1 和 hIK 通道无活性。 | |||
T8603 |
ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE 靶向前列腺素 E2受体 EP2亚型(人)。 | |||
T4138 |
UCPH-101
UCPH 101 |
transporter | Metabolism |
UCPH-101 是一种兴奋性氨基酸转运子亚型 1 (EAAT1) 的抑制剂(IC50:0.66 μM)。 | |||
T3547 |
Sotagliflozin
LX-4211,LP-802034 |
SGLT | GPCR/G Protein |
Sotagliflozin (LP-802034) 是有效的SGLT1/2抑制剂,用作抗糖尿病剂。 | |||
T23397 |
ST 91
|
Others; Adrenergic Receptor | GPCR/G Protein; Neuroscience; Others |
ST-91 是一种 α2-肾上腺素能受体激动剂,具有混合的 α-肾上腺素能受体类型/亚型选择特征。 | |||
T12679 |
(Rac)-VU 6008667
|
Others; AChR | Neuroscience; Others |
(Rac)-VU 6008667 是一种选择性的毒蕈碱乙酰胆碱受体亚型 5(M5 NAM)负异位调节剂,IC50 为 1.8 μM,pIC50 为 5.75,具有较高的中枢神经系统渗透性。 | |||
T84293 |
SSR 180
SSR180711 |
AChR | Neuroscience |
SSR 180 是一种高效性且亚型选择性的 α7 激动剂具有可用于研究阿尔茨海默病和精神分裂症。 | |||
T26698 |
AZ044
|
PI4K | PI3K/Akt/mTOR signaling |
AZ044是 III 型磷脂酰肌醇-4-激酶α -亚型(PI4KIIIalpha)的有效选择性抑制剂。 | |||
T13241 |
UB 165 fumarate
UB-165 fumarate,UB165 fumarate |
AChR | Neuroscience |
UB 165 fumarate 是 nAChR 的激动剂,α4β2 亚型的部分激动剂,是 α3β2 亚型的全激动剂,其在大鼠脑中测得的结合到 [3H]-nicotine 的 Ki 值为 0.27 nM,可用于研究神经系统疾病。 | |||
T28680 |
SB-215505
SB215505,SB 215505 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
SB-215505 是一种具有亚型选择性的 5-HT2B 受体拮抗剂,抑制 5-HT2B,5-HT2A 和 5-HT2C。SB-215505 可用于研究前列腺癌。 | |||
T4540 |
ML-18
|
Bombesin Receptor | GPCR/G Protein |
ML-18是一种非肽铃蟾肽受体亚型-3 拮抗剂,能够抑制肺癌生长。 | |||
T12738L1 |
Rivanicline 2HCl
Rivanicline 2HCl(15585-43-0 Free base) |
AChR | Neuroscience |
Rivanicline 2HCl 是一种选择性神经元烟碱受体(neuronal nicotinic receptor) 的抑制剂,对α4β2 亚型的亲和力较高。 | |||
T1028 |
Moxonidine
莫索尼定,BDF5895,莫索尼啶 |
Imidazoline Receptor | Neuroscience |
Moxonidine (BDF5895) 是咪唑啉受体亚型 1 的选择性激动剂,用作抗高血压药物。 | |||
T8007 |
VU 0238429
SCR-1481B1,VU0238429 |
AChR | Neuroscience |
VU 0238429 (SCR-1481B1) 是毒蕈碱乙酰胆碱受体亚型 5 的正变构调节剂,EC50为1.16 μM。 | |||
T7136 |
AZD-6280
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
AZD-6280 是一种新型的亚型选择性 GABAAα2/3 受体阳性调节剂,用于治疗广泛性焦虑症。 | |||
T8434 |
SIB-1757
6-methyl-2-[(E)-phenyldiazenyl]pyridin-3 |
GluR | Neuroscience |
SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) 是高选择性非竞争性 mGlu5 受体拮抗剂 (IC50:0.4 μM) 。 | |||
T2497 |
MPEP hydrochloride
|
GluR | Neuroscience |
MPEP Hydrochloride 是一种有效且高度特异性的非竞争性拮抗剂,作用于 mGlu5 受体亚型,IC50为 36 nM,有抗焦虑和抗抑郁活性。 | |||
T63667 |
ONO-8713
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
ONO-8713 是一种选择性的前列腺素E受体亚型EP1拮抗剂,可用于研究圣经系统疾病和代谢相关疾病。 | |||
T2067 |
NS11394
NS 11394 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
NS11394 是可口服GABAA 的阳性变构调节剂 (PAM),Ki 值为 0.5 nM。它对GABAA 的选择性依次为 α5、α3、α2 和α1 受体,具有抗炎和抗焦虑活性。 | |||
T2053 |
ADX-47273
BA 94673139 |
GluR | Neuroscience |
ADX-47273 (BA 94673139) 是一种选择性和可透过血脑屏障的mGluR5阳性变构调节剂 ,具有抗精神病和增强认知的活性,增强谷氨酸 (50 nM) 反应的EC50值为 0.17 μM。 | |||
T40891 |
ADTL-SA1215
ADTL-SA1215 |
Others | Others |
ADTL-SA1215 is a novel, highly selective small-molecule compound that acts as a specific activator of SIRT3, a protein known to play a crucial role in modulating autophagy. This compound holds great potential in the treatment of triple-negative breast cancer, as it effectively targets the molecular pathways associated with this subtype of cancer. | |||
T2400 |
Candesartan Cilexetil
TCV-116,坎地沙坦酯,坎地沙坦西酯 |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Candesartan Cilexetil (TCV-116) 是一种血管紧张素II 拮抗剂,可用于治疗高血压。 | |||
T8711 |
PF-05186462
PF-05150122 |
Sodium Channel | Membrane transporter/Ion channel |
PF-05186462 (PF-05150122)是选择性的人Nav1.7电压依赖性钠通道抑制剂,IC50为 21 nM,与其他钠通道 (Nav 1.1、1.2、1.3、1.4、1.5、1.6 和 1.8) 相比,它对 Nav1.7显示出显著的选择性。PF-05186462在急性或慢性疼痛中具有研究价值。 | |||
T13316 |
VU0134992 hydrochloride
|
Potassium Channel | Membrane transporter/Ion channel |
VU0134992 hydrochloride 是一个亚型偏好的,具有口服活性和选择性的内向整流钾通道Kir4.1阻滞剂,IC50为 0.97 μM。在 -120 mV 时,VU0134992 hydrochloride 对同分 Kir4.1 比 Kir4.1/5.1 共分通道 (IC50=9 μM) 高出 9 倍的选择性。 | |||
T13318 |
VU0650786
|
GluR | Neuroscience |
VU0650786 是能透过中枢神经系统的,选择性谷氨酸受体亚型 3 的一种负变构调节剂,IC50值为 392 nM,有抗抑郁和抗焦虑活性。 | |||
T5511 |
L-765314
|
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
L-765314 是一种 α1b 肾上腺素能受体的选择性拮抗剂,其在大鼠和人体中的Ki 分别为 5.4 nM 和 2.0 nM。 | |||
T22534 |
8-Hydroxy-DPAT hydrobromide
7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-OH-DPAT hydrobromide |
5-HT Receptor | GPCR/G Protein; Neuroscience |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) 是一种选择性5-HT1A 激动剂,pIC50为 8.19。它对 5-HT1结合位点的亚型有近 1000 倍的选择性。 | |||
T5158 |
N-Desmethylclozapine
N-去甲基氯氮平,Desmethylclozapine,Normethylclozapine,Norclozapine |
Virus Protease; Dopamine Receptor; 5-HT Receptor; Opioid Receptor; AChR; Drug Metabolite | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience |
N-Desmethylclozapine (Desmethylclozapine) 是非典型抗精神病药 Clozapine 的主要活性代谢产物。它是血清素受体亚型 5-HT2C 的拮抗剂,IC50值为7.1 nM。 它也是多巴胺 D4 受体的拮抗剂和δ-阿片受体的激动剂。 | |||
T16881L |
SIB 1553A
|
AChR | Neuroscience |
SIB 1553A 是一种可口服且具有选择性的烟碱乙酰胆碱受体 (nAChRs) 激动剂,是烟碱乙酰胆碱受体的亚型选择性配体。SIB-1553A 是一种认知增强剂,可用于研究如阿尔茨海默病等与神经退行性相关的疾病。 | |||
T14975 |
CJ-42794
CJ-042794 |
Others | Others |
CJ-42794 (CJ-042794)是前列腺素受体 EP4的选择性拮抗剂, 抑制[3H]-PGE2与 EP4受体结合的平均 pKi 为8.5, 对 EP4选择性比 EP1, EP2和 EP3高200多倍。 | |||
T4298 |
JNJ-47965567
JNJ-479655 |
P2X Receptor | Membrane transporter/Ion channel; Neuroscience |
JNJ-47965567 (JNJ-479655) 是中枢通透性、高亲和力、选择性的P2X7拮抗剂,可用于探讨中枢 P2X7 在中枢神经系统病理生理模型中的作用。它对人和大鼠 P2X7 作用的pKi 值分别为 7.9 和 8.7。 | |||
T16499 |
Mardepodect
PF-2545920 |
PDE | Metabolism |
Mardepodect (PF-2545920) 是一种有效的、口服具有活性的、可透过血脑屏障的、选择性的 PDE10A 抑制剂,IC50=0.37 nM,比作用于其他 PDE 选择性高 1000 多倍。 | |||
T17197 |
UCL 2077
|
Others | Others |
UCL 2077 是癫痫相关 KCNQ 通道的亚型选择性阻滞剂,也是一种选择性慢后超极化通道阻滞剂,在培养的海马神经元中 IC50 为 500 nM,对 Ca2+ 通道、动作电位、输入电阻的影响小 ,以及超极化后的介质。 | |||
T1066 |
Ketanserin
R41468,凯他色林,Ketanserin tartrate,酮色林,Ketanserinum |
Potassium Channel; 5-HT Receptor; Autophagy | Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Ketanserin (Ketanserinum) 是一种喹唑啉衍生物和 5-羟色胺受体亚型 2 拮抗剂,具有潜在的抗高血压和抗血小板活性。它也浓度依赖性抑制 hERG 电流,IC50为 0.11 μM。 | |||
T1782L |
Canagliflozin hemihydrate
JNJ28431754,TA 7284,TA7284,TA-7284,JNJ 28431754,JNJ-28431754 |
SGLT | GPCR/G Protein |
Canagliflozin hemihydrate (TA 7284) (JNJ28431754 hemihydrate) 是一种选择性的 SGLT2 抑制剂,作用于表达 mSGLT2,rSGLT2 和 hSGLT2 的 CHO 细胞,IC50 分别为 2 nM,3.7 nM 和 4.4 nM。 | |||
T2389 |
Dapagliflozin
达格列净,BMS-512148 |
SGLT; HIF | Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein |
Dapagliflozin (BMS-512148) 是一种葡萄糖协同转运蛋白2 (SGLT2) 抑制剂,可与靶点竞争性结合。Dapagliflozin 可用于 2 型糖尿病的治疗,可以减少肾脏的葡萄糖重吸收,增加尿液中葡萄糖的排泄,从而降低血浆葡萄糖水平。 | |||
T26873 |
BMY-27709
BMY 27709,BMY27709 |
Influenza Virus | Microbiology/Virology |
BMY-27709 是一种流感病毒生长抑制剂,对 A/WSN/33 病毒生长的 IC50 值为 3-8 μM,对流感病毒的部分亚型也展现出抑制活性。BMY-27709 对 H1 和 H2 病毒感染的早期起作用,通过抑制血凝素蛋白展现其抗病毒活性。然而,BMY-27709 对 H3 亚型病毒以及 B 型/Lee/40 流感病毒没有作用。 | |||
T4460 |
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
BMS-512148 (2S)-1,2-propanediol, hydrate,达格列净 (2S)-1,2-丙二醇水合物,Dapagliflozin propanediol monohydrate |
SGLT | GPCR/G Protein |
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) 是 Dapagliflozin 1,2-propanediol, hydrate 的 S 型异构体,是竞争性葡萄糖协同转运蛋白2 抑制剂,可促进尿液中葡萄糖的排泄,可用于糖尿病的研究。它诱导 HIF1表达并减轻肾脏 IR 损伤。 | |||
T12684 |
Radioprotectin-1
5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid |
LPA Receptor | GPCR/G Protein |
Radioprotectin-1 是特异性的 LPA2 激动剂,对小鼠 LPA2 GPCR 的 EC50 为 25 nM,具有辐射保护和辐射缓解作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6608 |
NMDA
N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid |
Endogenous Metabolite; NMDAR; iGluR | Membrane transporter/Ion channel; Metabolism; Neuroscience |
NMDA (N-Methyl-D-aspartic acid) 是一种氨基酸,作为 D-异构体,是谷氨酸受体的 NMDA 受体亚型的定义激动剂。 | |||
TJS0341 |
7-Amino-4-(trifluoromethyl)coumarin
香豆素151,Coumarin 151,AFC,7-氨基-4-(三氟甲基)香豆素 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是一种荧光标记物,其激发和发射波长分别为400和500 nm,可用来灵敏的检测蛋白酶。 | |||
T26288 |
Clovamide
trans-Clovamide,N-trans-Caffeoy-L-dopa |
Apoptosis; Influenza Virus; ROS; Antibacterial | Apoptosis; Immunology/Inflammation; Microbiology/Virology |
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02882 |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)
CUB domain containing protein 1 |
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa. | |||
TMPY-01373 |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9. | |||
TMPY-01552 |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is B6DRA0. | |||
TMPY-04192 |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P04591. | |||
TMPY-00065 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)
Matrix protein VP40 |
EBOV | E. coli |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number is B8XCM9. | |||
TMPH-01709 |
Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc)
Mucin-5 subtype B, tracheobronchial,Mucin-5B,Sublin... |
Human | E. coli |
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is Q9HC84. | |||
TMPH-01522 |
HIV-2 (subtype A, isolate ROD) Protein Vpx (His)
vpx,Viral protein X,X ORF protein,Protein Vpx |
HIV-2 | P. pastoris (Yeast) |
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by... | |||
TMPH-01521 |
HIV-2 (subtype A, isolate BEN) Protein Vpx (His)
Protein Vpx,X ORF protein,Viral protein X,vpx |
HIV-2 | E. coli |
HIV-2 (subtype A, isolate BEN) Protein Vpx (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.2 kDa and the accession number is P18099. | |||
TMPY-04196 |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P18800. | |||
TMPY-00235 |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN50. | |||
TMPY-01408 |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc)
CUB domain containing protein 1 |
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 98 kDa. | |||
TMPH-00803 |
HBV-A subtype adw2 (strain Rutter 1979) Capsid protein (His)
C,Core antigen,HBcAg,p21.5,Core protein,Capsid protein |
HBV-A | E. coli |
HBV-A subtype adw2 (strain Rutter 1979) Capsid protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is P03148. | |||
TMPY-00038 |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is Q05320. | |||
TMPY-00067 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP24 Protein (His)
VP24 Protein |
EBOV | E. coli |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession number is B8XCN4. | |||
TMPY-04915 |
HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is Q9YUL5. | |||
TMPH-00808 |
HBV-D subtype ayw (isolate Japan/JYW796/1988) Protein X (His)
Peptide X,Protein X,HBx,pX,X |
HBV-D | E. coli |
HBV-D subtype ayw (isolate Japan/JYW796/1988) Protein X (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is Q9QMI3. | |||
TMPH-00816 |
HBV-A subtype adw2 (strain Rutter 1979) Large envelope protein (His)
Major surface antigen,Large surface protein,Large S protein,... |
HBV-A | E. coli |
HBV-A subtype adw2 (strain Rutter 1979) Large envelope protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.1 kDa and the accession number is P03141. | |||
TMPY-06486 |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is AFM77980.1. | |||
TMPY-00316 |
HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is Q03805. | |||
TMPY-00234 |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 59 kDa and the accession number is A0A0E3KN50. | |||
TMPH-00807 |
HBV-D subtype ayw (isolate France/Tiollais/1979) Protein X (His & SUMO)
Protein X,HBx,X,Peptide X,pX |
HBV-D | E. coli |
HBV-D subtype ayw (isolate France/Tiollais/1979) Protein X (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.6 kDa and the accession number is P03165. | |||
TMPY-00247 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP1/Glycoprotein Protein (His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP1/Glycoprotein Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.5 kDa and the accession number is B8XCN0. | |||
TMPY-04061 |
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP)
GP36 |
HIV | E. coli |
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 58.8 kDa and the accession number is L8B302. | |||
TMPY-00238 |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.5 kDa and the accession number is A0A0E3KN50. | |||
TMPY-04871 |
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc)
CUB domain containing protein 1 |
HIV | HEK293 Cells |
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.9 kDa and the accession number is O12164. | |||
TMPY-04194 |
HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His)
Gag-p24 |
HIV | E. coli |
HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.5 kDa and the accession number is O12157. | |||
TMPY-00236 |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q05320. | |||
TMPY-00232 |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 31.5 kDa and the accession number is Q05320. | |||
TMPY-06111 |
Human respiratory syncytial virus (RSV) (subtype A, strain Long) glycoprotein G Protein (His)
G Protein |
RSV | HEK293 Cells |
Human respiratory syncytial virus (RSV) (subtype A, strain Long) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27 kDa and the accession number is P20895-1. | |||
TMPY-00309 |
HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is O11407. | |||
TMPY-00425 |
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)
CUB domain containing protein 1 |
HIV | HEK293 Cells |
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249. | |||
TMPH-00815 |
HBV-A subtype adw2 (isolate Germany/991/1990) Capsid protein (His & Myc)
C,Capsid protein,Core protein,HBcAg,p21.5,Core antigen |
HBV-A | E. coli |
HBV-A subtype adw2 (isolate Germany/991/1990) Capsid protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.9 kDa and the accession number is P0C693. | |||
TMPY-00243 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP-RBD/Glycoprotein Protein (hFc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP-RBD/Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.1 kDa and the accession number is B8XCN0. | |||
TMPH-00805 |
HBV-C subtype ayw (isolate China/Tibet127/2002) Capsid protein (E. coli, His)
C,Capsid protein,p21.5,Core protein,HBcAg,Core antigen |
HBV-C | E. coli |
HBV-C subtype ayw (isolate China/Tibet127/2002) Capsid protein (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 27.1 kDa and the accession number is P0C6H7. | |||
TMPH-00804 |
HBV-C subtype ayw (isolate China/Tibet127/2002) Capsid protein (Yeast, His)
Capsid protein,Core antigen,HBcAg,p21.5,C,Core protein |
HBV-C | P. pastoris (Yeast) |
HBV-C subtype ayw (isolate China/Tibet127/2002) Capsid protein (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C6H7. | |||
TMPH-01519 |
HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc)
Viral protein R,vpr,Protein Vpr,R ORF protein |
HIV-1 | E. coli |
HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is O12160. | |||
TMPY-00312 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)
Sec61 α1 subunit (S. cerevisiae),Sec61 alpha 1 subunit (S. c... |
EBOV | E. coli |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.6 kDa and the accession number is X5GXS8. | |||
TMPY-04159 |
Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN50. | |||
TMPY-04150 |
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)
Gag-Pol |
HIV | E. coli |
HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 53.6 kDa and the accession number is P04585. | |||
TMPH-01520 |
HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)
vpr,R ORF protein,Protein Vpr,Viral protein R |
HIV-1 | E. coli |
HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2. | |||
TMPY-00281 |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)
|
EBOV | E. coli |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 79.1 kDa and the accession number is B0LPL6. | |||
TMPY-00041 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.3 kDa and the accession number is X5HMX4. | |||
TMPY-00216 |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)
|
EBOV | E. coli |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is B0LPL6. | |||
TMPY-00302 |
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)
|
HIV | HEK293 Cells |
HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58. | |||
TMPY-00219 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His)
VP24 Protein |
EBOV | E. coli |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession number is L7QHW5. | |||
TMPY-04161 |
HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His)
Gag-Pol |
HIV | E. coli |
HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 66.7 kDa and the accession number is P04585. | |||
TMPY-00043 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His)
|
EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is X5HMX4. | |||
TMPY-00178 |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05320. | |||
TMPY-00177 |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the accession number is B8XCN0. | |||
TMPY-04135 |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)
HCV-E1 |
HCV | HEK293 Cells |
Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22301 |
L-838417 D9
CTP354,CTP354 (C-21191),C-21191 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
L-838417 D9 (C-21191) 是 L-838417 的氘代物。其中L-838417 是亚型选择性GABAA 正变构调节剂,在 α2, α3 和 α5 亚型中作为部分激动剂。 | |||
T12176 |
Naratriptan D3 Hydrochloride
GR-85548A D3 |
Others | Others |
Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype. | |||
TMIJ-0153 |
Dapagliflozin-13C6 (glucitol-13C6)
|
||
Dapagliflozin-13C6 (glucitol-13C6) 是 Dapagliflozin 的 13C 的标记化合物。Dapagliflozin 的 CAS 号为 461432-26-8。Dapagliflozin竞争性的葡萄糖协同转运蛋白2 (SGLT2) 抑制剂,可促进尿液中葡萄糖的排泄,在糖尿病 (DM) 研究中具有价值。Dapagliflozin 诱导HIF1表达并减轻肾脏 IR 损伤。 | |||
TMIH-0190 |
Difamilast-d5
|
||
Difamilast-d5 是 Difamilast 的氘代化合物。Difamilast 的 CAS 号为 937782-05-3。Difamilast 是局部的、选择性的非甾体磷酸二酯酶 4 抑制剂,对 B 亚型抑制作用较好 (IC50=11.2 nM)。它在研究轻度至中度特应性皮炎方面有研究的价值。 | |||
T70960 |
Maprotiline-d3 hydrochloride
|
||
Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r... | |||
TMIJ-0308 |
Clozapine-d3
|
||
Clozapine-d3 是 Clozapine 的氘代化合物。Clozapine 的 CAS 号为 5786-21-0。Clozapine 是一种三环二苯二氮卓类药物,属于非典型抗精神病药物。它结合几种类型的中枢神经系统受体,并显示出独特的药理学特征。 它是一种血清素拮抗剂,与 5-HT 2A/2C 受体亚型具有强结合力。它还对几种多巴胺能受体表现出很强的亲和力,但对多巴胺 D2 受体仅表现出较弱的拮抗作用,这种受体通常被认为可调节精神抑制活性。 |