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Search Results for " radicals "

Targets Recommended: Beta Amyloid

59

抑制剂 & 化合物

40

天然产物

2

化合物库

15

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L2910	抗氧化化合物库		1314 compounds
	氧化应激（Oxidative Stress，OS）是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧（ROS）大量积累，氧化程度超出抗氧化物的清除能力，从而引起氧化损伤，氧化应激损伤是许多疾病发生的基础，不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激，降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合，是研究氧化应激的有用工具，可以用于高通量筛选和高内涵筛选。
L6120	黄酮类天然产物库		514 compounds
	514 种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

抗氧化化合物库

Cat.No: L2910

Compounds: 1314

黄酮类天然产物库

Cat.No: L6120

Compounds: 514

Cat. No.	Product Name	Target	Signaling Pathways
T6495	EUK-134 EUK 134,乙基双亚氨基甲基愈创木酚锰氯化物	Beta Amyloid	Neuroscience
	EUK-134 是合成的超氧化物歧化酶和过氧化氢酶模拟物，可保护大鼠肾脏免受缺血再灌注引起的损伤。它作用于 H9C2 细胞，降低NF-κB 表达、MDA 水平和蛋白质羰基化。它是具有过氧化氢酶活性的超氧化物歧化酶 (SOD) 模拟物 (SODm)。它是保护有丝分裂的抗氧化剂。
T33602	NBD-Pen NBDPen,LipiRADICAL Green,NBD Pen,FDV-0042,Funakoshi
	NBD-Pen (LipiRADICAL Green) 是一种可检测活细胞中的脂质自由基的荧光探针。
T22739	DMPO 5,5-二甲基-1-吡咯啉-N-氧化物,5,5-Dimethyl-1-pyrroline N-oxide	Others	Others
	DMPO (5,5-Dimethyl-1-pyrroline N-oxide) 是一种亲水自旋诱捕剂，具有细胞渗透性。DMPO 可用于超氧化物检测，可检测超氧阴离子和羟自由基。
T19023	Lucigenin NSC-151912,L-6868,光泽精	Others	Others
	Lucigenin (NSC-151912) 是化学发光探针，可用于检测内源性产生的超氧阴离子自由基在细胞的存在。
T0701	Broxyquinoline Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline,溴羟喹啉	Antibiotic; Parasite	Microbiology/Virology
	Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) 是一种有效的发热伴血小板减少综合症病毒 (SFTSV) 抑制剂，IC50为 5.8 µM。Broxyquinoline 是一种抗原虫药。
T20509	Lophine 2,4,5-Triphenylimidazole,2，4，5-三苯基咪唑,NSC 62790,NSC-62790,NSC62790	Others	Others
	Lophine (NSC-62790) 用于合成蛋白激酶抑制剂、钙拮抗剂、强心强心剂和抗肿瘤药物。 Lophine 衍生物作为体外化学发光活化剂用于检测自由基。
T19428	Mito-TEMPO	Reactive Oxygen Species; Mitochondrial Metabolism	Immunology/Inflammation; Metabolism; NF-κB
	Mito-TEMPO 是一种线粒体靶向超氧化物歧化酶的模拟物。Mito-TEMPO 可以清除超氧化物和烷基自由基，防止线粒体的氧化、坏死和凋亡。
T64781	Biotin-4-aminophenol
	Biotin-4-aminophenol (BP) 是一种具有选择性和有效性的生物素-苯酚类似物，通过产生自由基并与蛋白质中的酪氨酸残基结合。
T21233	Dihydrolipoic acid Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸	Antioxidant	oxidation-reduction
	Dihydrolipoic acid (USAF XR-12) 是高效的抗氧化剂，对所有以氧为中心的自由基都有很强的清除能力。它在多种疾病中表现出抗炎特性。在 LPS 诱导的疾病行为大鼠中，它通过 ERK/Nrf2/HO-1/ROS/NLRP3 通路发挥预防作用。它还可以可用于抑郁症的研究。
TP2321L	H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate（159147-88-3 free base)	Others	Others
	H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate（159147-88-3 free base) 通过与活性氧物质（如超氧化物和羟基自由基）反应而起到抗氧化剂的作用。
T0223	Tetrahydroxyquinone 4-benzoquinone,四羟基苯醌,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis; Antioxidant; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Tetrahydroxyquinone (Tetroquinone) 是一种苯醌，是一种抗白内障剂，具有氧化还原活性。它可与半醌自由基一起参与氧化还原循环，导致活性氧形成。
T0402	Octocrylene 奥克立林,Octocrilene	Others	Others
	Octocrylene (Octocrilene) 是有机紫外线过滤器，能够吸收 UVB 辐射和较短的 UVA 波长。它具有用于各种化妆品中的潜能，可以保护化妆品配方免受紫外线辐射，或是在防晒产品中提供适当的防晒系数。
T3647	HTHQ HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)) 是一种强力的亲脂性酚类抗氧化剂。它通过与活性氧直接反应，清除 ROS，从而形成更稳定的自由基，具有很强的抗氧化活性。
T1229	Erdosteine 厄多司坦,RV 144,KW-9144	NF-κB; Antibacterial; Adenosine deaminase	Metabolism; Microbiology/Virology; NF-κB
	Erdosteine (RV 144) 抑制脂多糖诱导的NF-κB 激活，具有粘液调节、抗菌、抗炎、抗氧化和自由基清除作用。
T63750	α-Amylase-IN-1	Antioxidant; Amylase	Metabolism; oxidation-reduction
	α-Amylase-IN-1 是一种 α-Amylase 抑制剂（ IC50： 0.5509 μM）。α-Amylase-IN-1 具有抗氧化 (antioxidant) 活性，清除 DPPH 自由基的 IC50 值为 53.49 μM，可用于研究糖尿病和氧化应激相关疾病。
T1488	Procarbazine hydrochloride NSC-77213 HCl,盐酸甲基苄肼,Procarbazine HCl	DNA Alkylator/Crosslinker; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Procarbazine hydrochloride (NSC-77213 HCl) 是一种烷化剂，是甲基肼衍生物的盐酸盐，具有抗肿瘤和诱变活性。
T0893	Tinidazole 替硝唑,CP12574	Antibacterial; Antibiotic	Microbiology/Virology
	Tinidazole (CP12574) 是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑，是一种具有口服活性的抗菌剂。
T1562	Rebamipide Proamipide,OPC12759,瑞巴派特	Free radical scavengers; COX; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience; oxidation-reduction
	Rebamipide (OPC12759) 是一种粘膜保护剂，可诱导COX-2表达，增加PGE2水平，并以 COX-2 依赖性方式增强胃粘膜防御。
T0825	Ebselen SPI-1005,PZ-51,依布硒,CCG-39161	Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物，是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒，是HIV-1衣壳 CTD 二聚化的抑制剂，具有抗炎、抗癌和抗氧化活性。
T39434	HKOH-1
	HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals.
T39600	HKOH-1r
	HKOH-1r is a highly sensitive and selective fluorescent probe which is used for detecting endogenous hydroxyl radicals in living cells.
T35590	Graphislactone A	Others	Others
	Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.
T36500	Cyanidin 3-O-arabinoside	Others	Others
	Cyanidin 3-O-arabinoside is an anthocyanin antioxidant that has been found in eggplant. It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay.
T23816	BPIC	Others	Others
	BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.
T40936	Quinclorac	Others	Others
	Quinclorac, a commonly used agricultural herbicide, elicits oxidative stress by triggering the production of free radicals and altering the antioxidant defense system.
T21338	Methylprednisolone Acetate Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Methylprednisolone Acetate(Depo-Medrate) 具有抑制氧自由基的能力，可用于治疗急性脊髓损伤。
T40625	Plumbic acetate	Others	Others
	Plumbic acetate can provide either acetate radicals or acetoxonium ions. Plumbic acetate may be an acceptable oxidising agent for the preparation of sulphur (VI) systems, as witnessed by its reaction with thiodithiazyl dichloride.
T76576	Arg-Tyr
	Arg-Tyr 是一种具有强羟自由基和过氧化氢清除活性的二肽。
T36175	AAPH	Others	Others
	AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces molecular nitrogen and 2 carbon radicals. The carbon radicals may combine to produce stable products or react with molecular oxygen to give peroxyl radicals. The half-life of AAPH is about 175 hours (37°C at neutral pH), making the rate of free radical generation essentially con...
T36501	CYPMPO RR 071	Others	Others
	CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C),...
T75354	RH-EDA	Others	Others
	RH-EDA 是一种基于罗丹明的开启式荧光探针，用于检测生命系统中的羟基自由基。
T38099	APF
	APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxim...
T41058	Nelonemdaz potassium Neu2000potassium,Salfaprodil	Others	Others
	Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by both NMDA and free radicals, in addition to its role as a free radical scavenger.
T61312	Antioxidant agent-3	Others	Others
	Antioxidant agent-3 (Compound 14q) 是一种抗氧化剂，具有有效的DPPH 自由基清除活性和ABTS+清除活性，IC50分别为 26.58 和 30.31 μM。Antioxidant agent-3 作用于 H2O2处理的 HepG2 细胞，可增加活性氧 (ROS)、超氧化物歧化酶 (SOD) 和谷胱甘肽 (GSH)，并减少乳酸脱氢酶(LDH)。
T68675	Porfiromycin	Others	Others
	Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells.
T60434	Pentifylline	Others	Others
	Pentifylline 是一种血管扩张剂，可抑制血小板聚集和血栓素 A2 合成，减少自由基释放，并可能具有神经保护的作用。
T78360	Glyceraldehyde phosphate dehydrogenase GAPDH,G3PDH,GADPH	Others	Others
	Glyceraldehyde phosphate dehydrogenase是一种酶，既是抗胸腺细胞剂也是抗凋亡剂的靶点，它负责催化过羟基自由基对还原型烟酰胺腺嘌呤二核苷酸（NADH）的链氧化反应。
T35708	N-acetyl-5-Aminosalicylic Acid	Others	Others
	N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases. It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM. N-acetyl-5-Aminosalicylic acid (100 μM) scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by ...
T75332	7-Hydroxy-4-methyl-2(1H)-quinolone
	7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) 是一种荧光产物，主要用于检测 DNA 损伤的羟基自由基。储存时需避光。
T36174	Methyl 3,4-Dihydroxyphenylacetate	Others	Others
	Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0.0025 mg/ml).1Methyl 3,4-dihydroxyphenylacetate (0.01 μg/ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2 1.Nahar, L., Russell, W.R., Middleton, M., et al.Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumActa Pharm.55(2)187-193(2005) 2...
T38071	HPF
	The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aroma...
T38370	CAY10731
	CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.
T80909	Tyrosinase-IN-19	Tyrosinase	Proteases/Proteasome
	Tyrosinase-IN-19 是竞争性酪氨酸酶抑制剂，对ROS、ABTS+ 及DPPH 自由基展现显著的抗氧化活性。该化合物通过剂量依赖性方式有效抑制酪氨酸酶表达。
T83816	Cytidine-5'-O-(2-thiodiphosphate) sodium CDP-β-S	Others	Others
	Cytidine-5’-O-(2-thiodiphosphate) (CDP-β-S) 是一种不可水解的CDP衍生物，具有抗氧化活性。在Trolox等效吸收能力(TEAC)测定中，该化合物在5至20 µM的浓度范围内清除自由基。
T34112	Porfimer Sodium DHE,dihematoporphyrin ether,CL184116,CL-184116,CL 184116,Porfimer	Others	Others
	Porfimer sodium is t he sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen radicals after activation by 630 nm w
T36397	TAN 420E	Others	Others
	TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml. TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 μg/ml). It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 μg/ml, respectively).
T81864	MAQAAEYYR
	MAQAAEYYR 是从C-藻蓝蛋白的胰酶水解产物中分离得到的一种具备显著抗氧化活性的肽。它在DPPH和ABTS自由基清除实验中显示出较高的效率，并能有效保护斑马鱼幼虫免遭H2O2诱导的氧化伤害。
T36027	DEPMPO-biotin	Others	Others
	DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance. It is noted for the stability of adducts formed. DEPMPO can be used in vitro or in vivo, as it crosses lipid bilayer membranes and is a good trapping agent in biological systems. DEPMPO-biotin is a biotinylated form of DEPMPO which retains the outstanding persistency of its adducts. The biotin moiety offers an effective...
T69014	Sekikaic Acid	Others	Others
	Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µM. Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 µg/ml). It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 µM).
T35962	MitoPBN	Others	Others
	MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial membrane potential uncoupler FCCP . MitoPBN inhibits superoxide activation of mitochondrial uncoupling protein 1 (UCP1), UCP2, and UCP3 when used at a concentration of 250 nM in vitro but does not react with superoxide. It traps hydroxyl (IC50 = ~77 μM) and carbon-centered radical...

化合物

Cat.No: T6495

Synonym: EUK 134,乙基双亚氨基甲基愈创木酚锰氯化物

Target: Beta Amyloid

Cat.No: T33602

Synonym: NBDPen,LipiRADICAL Green,NBD Pen,FDV-0042,Funakoshi

Cat.No: T22739

Synonym: 5,5-二甲基-1-吡咯啉-N-氧化物,5,5-Dimethyl-1-pyrroline N-oxide

Target: Others

Cat.No: T19023

Synonym: NSC-151912,L-6868,光泽精

Target: Others

Cat.No: T0701

Synonym: Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline,溴羟喹啉

Target: Antibiotic, Parasite

Cat.No: T20509

Synonym: 2,4,5-Triphenylimidazole,2，4，5-三苯基咪唑,NSC 62790,NSC-62790,NSC62790

Target: Others

Cat.No: T19428

Target: Reactive Oxygen Species, Mitochondrial Metabolism

Biotin-4-aminophenol

Cat.No: T64781

Dihydrolipoic acid

Cat.No: T21233

Synonym: Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸

Target: Antioxidant

H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate

Cat.No: TP2321L

Synonym: H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate（159147-88-3 free base)

Target: Others

Tetrahydroxyquinone

Cat.No: T0223

Synonym: 4-benzoquinone,四羟基苯醌,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Cat.No: T0402

Synonym: 奥克立林,Octocrilene

Target: Others

Cat.No: T3647

Synonym: HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone

Target: Reactive Oxygen Species

Cat.No: T1229

Synonym: 厄多司坦,RV 144,KW-9144

Target: NF-κB, Antibacterial, Adenosine deaminase

α-Amylase-IN-1

Cat.No: T63750

Target: Antioxidant, Amylase

Procarbazine hydrochloride

Cat.No: T1488

Synonym: NSC-77213 HCl,盐酸甲基苄肼,Procarbazine HCl

Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis

Cat.No: T0893

Synonym: 替硝唑,CP12574

Target: Antibacterial, Antibiotic

Cat.No: T1562

Synonym: Proamipide,OPC12759,瑞巴派特

Target: Free radical scavengers, COX, Prostaglandin Receptor

Cat.No: T0825

Synonym: SPI-1005,PZ-51,依布硒,CCG-39161

Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease

Cat.No: T39434

Cat.No: T39600

Graphislactone A

Cat.No: T35590

Target: Others

Cyanidin 3-O-arabinoside

Cat.No: T36500

Target: Others

Cat.No: T23816

Target: Others

Cat.No: T40936

Target: Others

Methylprednisolone Acetate

Cat.No: T21338

Synonym: Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod

Target: Reactive Oxygen Species

Plumbic acetate

Cat.No: T40625

Target: Others

Cat.No: T76576

Cat.No: T36175

Target: Others

Cat.No: T36501

Synonym: RR 071

Target: Others

Cat.No: T75354

Target: Others

Cat.No: T38099

Nelonemdaz potassium

Cat.No: T41058

Synonym: Neu2000potassium,Salfaprodil

Target: Others

Antioxidant agent-3

Cat.No: T61312

Target: Others

Cat.No: T68675

Target: Others

Cat.No: T60434

Target: Others

Glyceraldehyde phosphate dehydrogenase

Cat.No: T78360

Synonym: GAPDH,G3PDH,GADPH

Target: Others

N-acetyl-5-Aminosalicylic Acid

Cat.No: T35708

Target: Others

7-Hydroxy-4-methyl-2(1H)-quinolone

Cat.No: T75332

Methyl 3,4-Dihydroxyphenylacetate

Cat.No: T36174

Target: Others

Cat.No: T38071

Cat.No: T38370

Tyrosinase-IN-19

Cat.No: T80909

Target: Tyrosinase

Cytidine-5'-O-(2-thiodiphosphate) sodium

Cat.No: T83816

Synonym: CDP-β-S

Target: Others

Porfimer Sodium

Cat.No: T34112

Synonym: DHE,dihematoporphyrin ether,CL184116,CL-184116,CL 184116,Porfimer

Target: Others

Cat.No: T36397

Target: Others

Cat.No: T81864

Cat.No: T36027

Target: Others

Cat.No: T69014

Target: Others

Cat.No: T35962

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TQ0211	Brusatol (+)-Brusatol,鸦胆子苦醇,NSC 172924	Others; Ferroptosis; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Brusatol (NSC-172924) 是一种从鸦胆子植物中分离出来的天然产物，抑制Nrf2通路，可使多种癌细胞对 Cisplatin 和其他化疗药物敏感。它可开发为辅助化疗化合物，可增加细胞凋亡。
T8177	Galactinol	Others	Others
	Galactinol Hydrate 清除羟基自由基并保护植物细胞免受氧化损伤。
TJS0315	4-Methyldaphnetin 7,8-Dihydroxy-4-methylcoumarin,4-甲基瑞香素,DHMC,7,8-二羟基-4-甲基香豆素	Apoptosis; Lipoxygenase	Apoptosis; Metabolism
	4-Methyldaphnetin (DHMC) 是一种合成 4-甲基香豆素衍生物的前体。它对几种肿瘤细胞株具有选择性的抗增殖和诱导凋亡的作用。它能够清除自由基，显著抑制膜脂过氧化。
T4931	Dihydroxyfumaric acid hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Dihydroxyfumaric acid hydrate 是内源性代谢产物的一种。
T6S1930	Schisanhenol 五味子酚,Schizanhenol,Gomisin-K3	Antioxidant	oxidation-reduction
	Schisanhenol (Schizanhenol) 是一种UGT2B7的抑制剂，是一种天然化合物。
T5S0285	Cistanoside A 肉苁蓉苷 A,肉苁蓉苷A	Others	Others
	Cistanoside A 是一种肉苁蓉中的苯丙素类化合物，能够抑制 NO 的聚集，但不影响诱导型一氧化氮合酶 iNOS 的 mRNA 和蛋白水平及其活性。它具有抗炎作用。
T5S0089	Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside,百蕊草素I	Antioxidant; p38 MAPK; NF-κB	MAPK; NF-κB; oxidation-reduction
	Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside) 是来源于百蕊草的一种类黄酮，在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T19792	1,3,7-Trimethyluric acid	Others	Others
	1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。
T1085	L-Glutathione reduced 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion	Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	L-Glutathione reduced (Glutathione) 属于天然三肽，存在与细胞中，是一种内源性抗氧化剂，可以清除氧自由基。L-Glutathione reduced 是某些酶的辅助因子，参与蛋白质二硫键重排并减少过氧化物。
T3S0289	Araloside X	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
TN1601	Effusol 灯心草菲酚,厄弗酚	Caspase	Apoptosis; Proteases/Proteasome
	Effusol 是一种从 Juncus effuses 中分离到的酚类物质，对 DPPH 自由基(IC50:79 μM) 及 ABTS 自由基(IC50:2.73 μM)具有较强的清除活性。它能挽救皮质酮减弱的 CA1 LTP，保护海马功能对抗应激诱导的认知能力下降。
T0562	Protocatechuic acid 3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid	Others	Others
	Protocatechuic acid (3, 4-Dihydroxybenzoic acid) 是天然的多酚类物质，具有神经保护活性。
T4704	L-Anserine nitrate L-鹅肌肽硝酸盐,L-Anserine nitrate salt	Others; Endogenous Metabolite	Metabolism; Others
	L-Anserine nitrate (L-Anserine nitrate salt) 是一种存在于大多数动物组织中的二肽。在模型系统中，它是一种有效的抗氧化剂和羟基自由基清除剂。该化合物抑制醛糖和酮糖还原糖诱导的非酶蛋白糖基化。
T5S2254	Swertianolin Bellidifolin-8-O-Glucoside,当药醇苷	Others; HBV; Antibacterial; AChE	Microbiology/Virology; Neuroscience; Others
	Swertianolin (Bellidifolin-8-O-Glucoside) 是从Gentianella Acuta 分离得到的一种黄酮，具有抗 HBV 和抗菌活性，可抑制乙酰胆碱酯酶。
T7984	2-Hydroxyflavanone	Others	Others
	2-Hydroxyflavanone 是一种天然存在的黄酮类化合物，存在于许多植物和水果中。它具有抗氧化、抗炎和抗肿瘤的活性，可以清除自由基，减少炎症，并抑制肿瘤细胞的生长，还具有治疗糖尿病、肥胖症、心血管疾病和神经系统疾病等多种疾病的潜力。
T3606	γ-Oryzanol 谷维素,Gamma-Oryzanol,Oliver,γ-谷维素,Gammariza	DNA Methyltransferase	Chromatin/Epigenetic
	γ-Oryzanol (Gamma-Oryzanol) 是一种从米糠油中分离出来的营养提取物，是含有甾醇和阿魏酸的混合物，有助于破坏皮肤中的自由基。它有效抑制小鼠纹状体中的 DNA 甲基转移酶(DNMTs)。它抑制DNMT1和DNMT3a，IC50分别为 3.2 和 22.3 μM。
T3388	Calycosin-7-O-β-D-glucoside 毛蕊异黄酮苷,calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside	MMP; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
	Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) 是一种异黄酮，从黄芪中分离得到。它具有多种生物活性，包括心脏保护、神经保护、抗炎和抗氧化作用。
T41242	Uric acid sodium 尿酸钠	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Uric acid sodium 是氧自由基 (oxygen radical) 的清除剂，是一种有效的、常见的抗氧化剂，有助于维持机体血压稳定和抗氧化应激。Uric acid sodium 能清除活性氧 (ROS)，如单线态氧和过氧亚硝酸盐，对脂质过氧化有抑制作用，与痛风性关节病的发病机理和草酸钙结石的形成有关。
TN1962	Myricetin 3-O-galactoside Myricetin 3-O-beta-D-galactopyranoside	NOS; Xanthine Oxidase	Immunology/Inflammation; Metabolism
	Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) 可抑制黄嘌呤氧化酶 (xanthine oxidase; XO) 活性，脂质过氧化并清除自由基。杨梅素3- o -半乳糖苷具有很多作用包括细胞毒性、抗氧化、抗基因毒性、抗感染性、抗炎作用和抗氧化活性，其主要作用是抑制诱导型一氧化氮合酶(iNOS)的合成。Myricetin 3-O-galactoside 抑制脂质过氧化的 IC50 为 160 μg/mL。
TN1831	Macranthoside A Kalopanaxsaponin H	Antioxidant	oxidation-reduction
	Macranthoside A (Kalopanaxsaponin H) 是一种从地黄中提取的三萜糖苷，属于环烯醚萜类化合。Macranthoside A 具有抗炎、抗氧化、抗菌和神经保护活性，抑制促炎细胞因子的产生和抑制炎症信号通路的激活，有助于中和有害的自由基，保护细胞免受氧化损伤，可以促进神经元的存活和生长，并防止氧化应激或神经毒性化合物引起的神经元细胞死亡，具有治疗神经退行性疾病、心血管疾病和肝损伤的潜力。
T35749	Thymohydroquinone Thymoquinol	Antioxidant; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Thymohydroquinone (Thymoquinol) 是中药材百里香、牛至和其他唇形科植物中含有的单萜酚类化合物。 Thymohydroquinone 抑制癌细胞生长、减少氧化应激和调节炎症反应，在无细胞实验中清除2,2-二苯基-1-picrylhydrazyl 自由基(IC50 = 2.4 μg/ml)，在浓度为1.6至6.4 μg/ml 的氧自由基吸收能力(ORAC)实验中，它的Trolox 当量值为2.6胸腺对苯二酚对A2780、OVCAR-8和CIS-A2780卵巢癌细胞(IC50分别为3.1、8.9和9.8 μM)和人卵巢永生化上皮细胞(IC50 = 14 μM)的生长有抑制作用，体外对恶性疟原虫也有抑制作用(IC50 = 15.9 μM)。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
TN3677	Cleroindicin B	Others	Others
	Cleroindicin B shows weak scavenging action on 2,2-diphenyl-l-picrylhydrazyl and hydroxyl radicals.
TN2013	Ophiopogonanone A	Others	Others
	Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
TN2015	Ophiopogonanone E	Others	Others
	Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
TN4404	Ladanein	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities against K562, K562R (imatinib-resistant), and 697 human leukemia cell lines.
TN1431	Baohuoside VII 宝藿苷,宝藿苷VII	Others	Others
	Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VII in vivo exhibits significant anti
TN5471	5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one
	5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(Â·OH) and hydrogen peroxide(H2O2) in vitro.It shows a strong cytotoxic activity on HeLa-S3 cell.
T36513	Pyranonigrin A	Others	Others
	Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).
TN3380	Alloisoimperatorin	AChR	Neuroscience
	Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity
T83026	Antioxidant agent-18
	Antioxidant agent-18（compound 5）为一种从银杏（Ginkgo biloba）中提取的黄酮醇苷，展现出显著的抗氧化特性。本化合物能有效清除DPPH自由基（IC50: 15.8 μM），同时具有还原细胞色素c的能力（IC50: 14.7 μM）。
TN4263	Isoangustone A	MMP; GSK-3; NF-κB; ROS; Akt; PI3K; CDK; JNK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-ÎºB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
T75699	Coenzyme Q6	Others	Others
	Coenzyme Q6 (Ubiquinone 30)，一种异戊二烯化的苯醌脂质，主要在呼吸电子传输链中发挥作用，并作为脂质抗氧化剂，具备抗氧化性能，能够防止自由基生成和氧化损伤。
TMA0291	Dehydroglyasperin D	GSK-3; p38 MAPK; ROS; Akt; COX; PI3K; DNA/RNA Synthesis; Prostaglandin Receptor; JNK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; MAPK; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet o...
TN4605	Myriceric acid B	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 val
TN2243	Sugiol 10-Deoxoxanthoperol	IL Receptor; TNF; ROS	Apoptosis; Immunology/Inflammation
	Sugiol (10-Deoxoxanthoperol) 是一种枞烷二萜，可从台湾板栗树 (Calocedrus formosana) 的树皮中分离出来。Sugiol 具有抗炎活性，可有效减少脂多糖 (LPS) 刺激巨噬细胞后的活性氧 (ROS) 产生。
T36179	Aspulvinone O	Others	Others
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...
T35758	Butyrolactone V	Others	Others
	Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also...
T83876	L-Ascorbic Acid 6-stearate L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid	Others	Others
	L-抗坏血酸6硬脂酸酯是L-抗坏血酸与硬脂酸的衍生物，在K. coccinea中发现，具有抗氧化和抗癌作用。在细胞外试验中清除DPPH（IC50 = 3.31 µg/ml）。包裹L-抗坏血酸6硬脂酸酯的脂质纳米颗粒（LNPs）在190 µM浓度下诱导HL-60前髓母细胞凋亡。含有L-抗坏血酸6硬脂酸酯的配方已用于化妆品和个人护理产品中。
T36000	3-Hydroxyterphenyllin	Others	Others
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...

天然产物

Cat.No: TQ0211

Synonym: (+)-Brusatol,鸦胆子苦醇,NSC 172924

Target: Others, Ferroptosis, Nrf2

Cat.No: T8177

Target: Others

4-Methyldaphnetin

Cat.No: TJS0315

Synonym: 7,8-Dihydroxy-4-methylcoumarin,4-甲基瑞香素,DHMC,7,8-二羟基-4-甲基香豆素

Target: Apoptosis, Lipoxygenase

Dihydroxyfumaric acid hydrate

Cat.No: T4931

Target: Others, Endogenous Metabolite

Cat.No: T6S1930

Synonym: 五味子酚,Schizanhenol,Gomisin-K3

Target: Antioxidant

Cat.No: T5S0285

Synonym: 肉苁蓉苷 A,肉苁蓉苷A

Target: Others

Kaempferol-3-O-glucorhamnoside

Cat.No: T5S0089

Synonym: Kaempferol 3-glucorhamnoside,百蕊草素I

Target: Antioxidant, p38 MAPK, NF-κB

1,3,7-Trimethyluric acid

Cat.No: T19792

Target: Others

L-Glutathione reduced

Cat.No: T1085

Synonym: 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Cat.No: T3S0289

Target: Calcium Channel

Cat.No: TN1601

Synonym: 灯心草菲酚,厄弗酚

Target: Caspase

Protocatechuic acid

Cat.No: T0562

Synonym: 3, 4-Dihydroxybenzoic acid,3,4-二羟基苯甲酸,Protocatechuate,原儿茶酸,3,4-Dihydroxybenzoic acid

Target: Others

L-Anserine nitrate

Cat.No: T4704

Synonym: L-鹅肌肽硝酸盐,L-Anserine nitrate salt

Target: Others, Endogenous Metabolite

Cat.No: T5S2254

Synonym: Bellidifolin-8-O-Glucoside,当药醇苷

Target: Others, HBV, Antibacterial, AChE

2-Hydroxyflavanone

Cat.No: T7984

Target: Others

Cat.No: T3606

Synonym: 谷维素,Gamma-Oryzanol,Oliver,γ-谷维素,Gammariza

Target: DNA Methyltransferase

Calycosin-7-O-β-D-glucoside

Cat.No: T3388

Synonym: 毛蕊异黄酮苷,calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside

Target: MMP, Reactive Oxygen Species

Uric acid sodium

Cat.No: T41242

Synonym: 尿酸钠

Target: Reactive Oxygen Species

Myricetin 3-O-galactoside

Cat.No: TN1962

Synonym: Myricetin 3-O-beta-D-galactopyranoside

Target: NOS, Xanthine Oxidase

Macranthoside A

Cat.No: TN1831

Synonym: Kalopanaxsaponin H

Target: Antioxidant

Thymohydroquinone

Cat.No: T35749

Synonym: Thymoquinol

Target: Antioxidant, Reactive Oxygen Species

Epimedokoreanin B

Cat.No: TN3972

Target: Apoptosis, Others, Antibacterial

Cat.No: TN3677

Target: Others

Ophiopogonanone A

Cat.No: TN2013

Target: Others

Ophiopogonanone E

Cat.No: TN2015

Target: Others

Cat.No: TN4404

Target: HCV Protease

Cat.No: TN1431

Synonym: 宝藿苷,宝藿苷VII

Target: Others

5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one

Cat.No: TN5471

Cat.No: T36513

Target: Others

Alloisoimperatorin

Cat.No: TN3380

Target: AChR

Antioxidant agent-18

Cat.No: T83026

Cat.No: TN4263

Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK

Cat.No: T75699

Target: Others

Dehydroglyasperin D

Cat.No: TMA0291

Target: GSK-3, p38 MAPK, ROS, Akt, COX, PI3K, DNA/RNA Synthesis, Prostaglandin Receptor, JNK

Myriceric acid B

Cat.No: TN4605

Target: HIV Protease

Cat.No: TN2243

Synonym: 10-Deoxoxanthoperol

Target: IL Receptor, TNF, ROS

Cat.No: T36179

Target: Others

Butyrolactone V

Cat.No: T35758

Target: Others

L-Ascorbic Acid 6-stearate

Cat.No: T83876

Synonym: L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid

Target: Others

3-Hydroxyterphenyllin

Cat.No: T36000

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01318	SOD3 Protein, Human, Recombinant SOD3,Extracellular superoxide dismutase [Cu-Zn]	Human	E. coli
	Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 24.1 kDa and the accession number is P08294.
TMPH-02917	SOD1 Protein, Mouse, Recombinant (E. coli, His) Superoxide dismutase [Cu-Zn],Sod1	Mouse	E. coli
	Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.8 kDa and the accession number is P08228.
TMPH-00052	Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI) sodB,Superoxide dismutase [Fe]	Anabaena	E. coli
	Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 16.4 kDa and the accession number is P83157.
TMPH-02918	SOD1 Protein, Mouse, Recombinant (His) Sod1,Superoxide dismutase [Cu-Zn]	Mouse	P. pastoris (Yeast)
	Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.8 kDa and the accession number is P08228.
TMPH-03378	SOD1 Protein, Rat, Recombinant (His) Sod1,Superoxide dismutase [Cu-Zn]	Rat	P. pastoris (Yeast)
	Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.3 kDa and the accession number is P07632.
TMPY-01585	SOD1 Protein, Human, Recombinant (His) SOD,homodimer,ALS,hSod1,IPOA,superoxide dismutase 1, soluble...	Human	E. coli
	SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis....
TMPH-01317	SOD3 Protein, Human, Recombinant (His) SOD3,Extracellular superoxide dismutase [Cu-Zn]	Human	E. coli
	Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.1 kDa and the accession number is P08294.
TMPH-03612	SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Superoxide dismutase [Cu-Zn],sodC	Mycobacterium tuberculosis	E. coli
	Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P9WGE8.
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His) Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
TMPJ-00946	TALDO1 Protein, Human, Recombinant (His) Transaldolase,TALDO1,TAL,TALDOR,TALDO	Human	HEK293 Cells
	Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the sk...
TMPH-00035	Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) Tyrosinase 2,Cresolase 2,PPO2,Polyphenol oxidase 2	Agaricus bisporus	Baculovirus Insect Cells
	Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell...
TMPJ-00887	NFKB1 Protein, Human, Recombinant (His) Nuclear factor of κ light polypeptide gene enhancer in B-cel...	Human	E. coli
	The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory...
TMPJ-00104	SOD2 Protein, Human, Recombinant (E. coli, His) SOD2,Superoxide Dismutase [Mn] Mitochondrial	Human	E. coli
	Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron dis...
TMPJ-00979	GSH-S Protein, Human, Recombinant (His) Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,Glutathione ...	Human	E. coli
	Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...
TMPY-02209	CUTC Protein, Human, Recombinant (His) CGI-32,cutC copper transporter	Human	E. coli
	Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply o...

重组蛋白

SOD3 Protein, Human, Recombinant

Cat.No: TMPH-01318

Species: Human

Expression System: E. coli

SOD1 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02917

Species: Mouse

Expression System: E. coli

Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI)

Cat.No: TMPH-00052

Species: Anabaena

Expression System: E. coli

SOD1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02918

Species: Mouse

Expression System: P. pastoris (Yeast)

SOD1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03378

Species: Rat

Expression System: P. pastoris (Yeast)

SOD1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01585

Species: Human

Expression System: E. coli

SOD3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01317

Species: Human

Expression System: E. coli

SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Cat.No: TMPH-03612

Species: Mycobacterium tuberculosis

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01248

Species: Human

Expression System: E. coli

TALDO1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00946

Species: Human

Expression System: HEK293 Cells

Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)

Cat.No: TMPH-00035

Species: Agaricus bisporus

Expression System: Baculovirus Insect Cells

NFKB1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00887

Species: Human

Expression System: E. coli

SOD2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-00104

Species: Human

Expression System: E. coli

GSH-S Protein, Human, Recombinant (His)

Cat.No: TMPJ-00979

Species: Human

Expression System: E. coli

CUTC Protein, Human, Recombinant (His)

Cat.No: TMPY-02209

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T71326	1,3,7-Trimethyluric Acid-d9
	1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.

同位素标记化合物

1,3,7-Trimethyluric Acid-d9

Cat.No: T71326

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