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4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) 是一种具抗氧化特性的化合物,表现出IC50为1.25 mM的DPPH自由基清除能力,并在ORAC测试中显示抗氧化性能为11.7 mM TE(此值相当于11.7 mmol Trolox的抗氧化效力)。在Briggs–Rauscher反应中,它能延长氧化过程约9180秒。此外,4-Methoxyphenyl isothiocyanate 对胆碱酯酶有一定的抑制活性,抑制乙酰胆碱酯酶(AChE)的率为30.4%,抑制丁酰胆碱酯酶(BChE)的率为17.9%。因此,该化合物有望在抗氧化和神经系统疾病研究领域中发挥作用。
4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) 是一种具抗氧化特性的化合物,表现出IC50为1.25 mM的DPPH自由基清除能力,并在ORAC测试中显示抗氧化性能为11.7 mM TE(此值相当于11.7 mmol Trolox的抗氧化效力)。在Briggs–Rauscher反应中,它能延长氧化过程约9180秒。此外,4-Methoxyphenyl isothiocyanate 对胆碱酯酶有一定的抑制活性,抑制乙酰胆碱酯酶(AChE)的率为30.4%,抑制丁酰胆碱酯酶(BChE)的率为17.9%。因此,该化合物有望在抗氧化和神经系统疾病研究领域中发挥作用。
产品描述 | 4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies. |
别名 | 4-Methylphenyl ITC |
分子量 | 165.21 |
分子式 | C8H7NOS |
CAS No. | 2284-20-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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