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Search Results for " glutathione "
Targets Recommended: Glutathione Peroxidase Glutathione reductase Apoptosis AChR

157

抑制剂 & 化合物

43

天然产物

2

化合物库

44

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name
L2900 氧化还原化合物库

1264 compounds
1264 个活性化合物,已经验证具有一定的抗氧化活性,包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物,是研究疾病机理以及药物研究的优良载体
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

氧化还原化合物库
Cat.No: L2900
Compounds: 1264
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T27417L Glutathione arsenoxide hydrochloride

GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)

Apoptosis; AChR Apoptosis; Neuroscience
Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) 是一种潜在的抗癌活性分子和肿瘤代谢抑制剂。Glutathione arsenoxide hydrochloride 靶向线粒体内膜腺嘌呤核苷酸转移酶 (ANT),对细胞增殖有抑制作用,促进细胞凋亡。Glutathione arsenoxide hydrochloride 可用于识别如蛋白质二硫异构酶一样的细胞表面蛋白质。
T9978 Glutathione synthesis-IN-1

Others Others
Glutathione synthesis-IN-1 (DC-1)是谷胱甘肽合成抑制剂。
TN7044 S-(4-Hydroxybenzyl)glutathione

GluR Neuroscience
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] 是一种谷胱甘肽衍生物,能够抑制红藻氨酸与脑谷氨酸受体的体外结合(IC50:2 μM)。
T24807 S-Methylglutathione

Glutathione S-methyl ester,Glutathione ester,S-Methyl glutathione

Glyoxalase Proteases/Proteasome
S-Methylglutathione (S-Methyl glutathione) 是一种 S 取代的谷胱甘肽,是一种转移酶A催化的1-氯-2,4-二硝基苯偶联物的抑制剂,也是一种 XOCl 清除剂。S-Methylglutathione 抑制乙二醛酶 1 (glyoxalase 1) ,诱导水螅触手球形成。
T10956 Dansyl glutathione

DNS-glutathione

Others Others
Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.
T24782 S-Ethyl glutathione

Glutathione monoethyl ester,Glutathione ethyl ester,L-gamma-Glutamyl-S-ethyl-L-cysteinylglycine

Others Others
S-Ethyl glutathione is the enzyme Glyoxalase 1 inhibitor.
T68833 Glutathione sulfinanilide

Others Others
Glutathione sulfinanilide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70831 Glutathione maleimide

Others Others
Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T69992 Glutathione sodium

Others Others
Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T70331 Glutathione sulfonate

Others Others
Glutathione sulfonate is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T38312 L-Cysteine-glutathione disulfide

Others Others
L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity.
T36073 S-Acetyl-L-glutathione

Others Others
S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases ...
T78342 Glutathione reductase

EC 1.6.4.2

Others Others
Glutathione reductase (EC 1.6.4.2) 是维持还原型谷胱甘肽供应的还原酶。
T27417 Glutathione arsenoxide

GSAO

Others Others
Glutathione arsenoxide is a hydrophilic derivative of phenylarsine oxide (PAO), a protein tyrosine phosphatase inhibitor. Glutathione arsenoxide inhibits angiogenesis and tumour growth.
T36173 L-Glutathione, oxidized (sodium salt)

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The rat...
T70602 Glutathione glycylethyl ester

Others Others
Glutathione glycylethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T31949 Glutathione amide

GASH cpd,L-gamma-Glutamyl-L-cysteinylglycinamide

Others Others
Glutathione amide is a enzyme of a chimeric protein.
T19930 Nitrosoglutathione

S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO

RAAS; NO Synthase Endocrinology/Hormones; Immunology/Inflammation
Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体,是大鼠酒精脱氢酶III 类同工酶的底物,能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。
T31950 Glutathione monoisopropyl ester

YM737,YM 737,YM-737

Others Others
Glutathione monoisopropyl ester is a biochemical.
T31950L Glutathione monoisopropyl ester acetate (97451-46-2 Free base)

Glutathione monoisopropyl ester acetate (97451-46-2 Free base) 在生命科学相关研究中具有广泛的应用。
T71441 Glutathione palmitamide

Others Others
Glutathione palmitamide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T80056 Glutathione Peroxidase

GSH-Px,EC 1.11.1.9

Glutathione Peroxidase Metabolism
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9),是一种关键的抗氧化酶,能催化GSH与过氧化氢或脂质过氧化物反应,生成GSSG和H2O,从而减缓氧化应激。此酶在生化研究中具有重要应用。
T34605 Selenodiglutathione

Seleno-di-glutathione,Bis(glutathione) selenide

Others Others
Selenodiglutathione is a primary Se metabolite conjugated with two glutathione (GSH) moieties.
T68202 Glutathione diethyl ester

Glutathione diethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.
T78616 Glutathione ethyl ester

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Glutathione ethyl ester 为细胞渗透性的GSH供体,能为卵母细胞提供高效率的谷胱甘肽供给。该化合物通过提升抗氧化防御,对胚胎体外生产具有促进效应。
T35940 Darinaparsin

Dimethylarsinic glutathione,Darinaparsin

Others Others
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M), as well as Jurkat T cell lymphoma and L540 Hodgkin lymphoma cells (IC50s = 2.7 and 1.3 &#181M, respectively). [1][2] It decreases the tumor-initiating subpopulation in DU145 and PC3 cells and halts the cell cycle in the G2/M phase. Darinaparsin decreases transcription of Gli-2,...
T83780 GPX4 24

Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24

Others Others
GPX4 24是(1S,3R)-RSL3的衍生物,具有抑制谷胱甘肽过氧化物酶4(GPX4)的作用。它能够在浓度依赖的方式中与4T1小鼠乳腺癌细胞中的GPX4形成共价结合。在GPX4依赖的HT-1080成纤维细胞中,GPX4 24诱导铁死亡(EC50 = 0.16 µM)。当以200 mg/kg剂量给予小鼠时,它能够增加小鼠肾脏和血浆中丙二醛(MDA)的水平。
T81233 S-(p-Nitrobenzyl)glutathione

Others Others
S-(p-Nitrobenzyl)glutathione 是一种竞争性谷胱甘肽酶(GGT)抑制剂,能被大鼠肾微粒体转化成相应的半胱氨酸衍生物。该化合物用于研究谷胱甘肽酶系统中GSH的代谢及其降解过程。
T83926 S-Geranylgeranyl-L-glutathione

GGG

Others Others
S-Geranylgeranyl-L-glutathione是孤儿G蛋白偶联受体(GPCR)P2RY8的配体。该化合物在100 nM浓度下,选择性地诱导P2RY8而非鞘氨醇-1-磷酸受体2(S1P2)、GPR55、半胱氨酸白三烯受体1(CysLT1 receptor)以及CysLT2 receptor的内吞作用。在10 nM浓度下,S-Geranylgeranyl-L-glutathione抑制了表达P2RY8的WEHI-231 B细胞淋巴瘤细胞和分离的人扁桃体生发中心B细胞由趋化因子(C-X-C motif)配体12(CXCL12)诱导的迁移。
T81234 S-(1,2-Dicarboxyethyl)glutathione

S-(1,2-Dicarboxyethyl)glutathione为多肽类化合物,具有抑制血液凝固与血小板聚集的功能。
T37314 JKE-1674

GPX oxidation-reduction
JKE-1674 是口服有效的谷胱甘肽过氧化物酶 4 (GPX4)抑制剂,是ML-210的活性代谢物,ML-210也是GPX4抑制剂。它可转换成丁腈氧化物 JKE-1777。它用与 ML-210 相同的方式杀死 LOX-IMVI 细胞,并被ferroptosis 抑制剂完全挽救。
T80098 N,S-Bis-Fmoc-Glutathione

N,S-Bis-Fmoc-Glutathione为一有效glyoxalase II抑制剂,其Ki值达0.32 mM。
T14379 AZD5904

Glutathione Peroxidase Metabolism
AZD5904 是一种不可逆的人髓过氧化物酶选择性抑制剂,其IC50=140 nM,在小鼠和大鼠中也具有相似的效力。
T40588 Acifluorfen

Others Others
Acifluorfen 是一种除草剂。Acifluorfen 是一种原卟啉原氧化酶抑制剂,可促进原卟啉 IX 的积累,并诱导啮齿动物肝脏发生肿瘤。它会引起敏感植物物种中的色素和脂质强烈的光氧化破坏。
T5340 MPO-IN-28

Glutathione Peroxidase Metabolism
MPO-IN-28 是髓过氧化物酶 (MPO) 抑制剂,IC50=44 nM。
T8375 ML-210

CID 49766530

Ferroptosis; GPX; Glutathione Peroxidase; Ras Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction
ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂,EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合,具有抗癌活性。
T5481 TRi-1

Others Others
TRi-1 是不可逆的胞质硫氧还蛋白还原酶1 的特异性抑制剂(IC50:12 nM)。它有抗肿瘤作用,且线粒体毒性很小。
T4090 PF-06282999

Glutathione Peroxidase Metabolism
PF06282999 是选择性的髓过氧物酶 (myeloperoxidase) 抑制剂,用于研究心血管疾病。
T7831 Nitecapone

Others; Transferase Metabolism; Others
Nitecapone 是一个具有口服活性的、短效的儿茶酚-O-甲基转移酶(COMT)的抑制剂。它具有胃肠道保护和抗氧化活性,能够清除活性氧和一氧化氮,防止脂质过氧化。
T38155 N-Acetyl-D-cysteine

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
N-Acetyl-D-cysteine 具有抗氧化活性,机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine 不能进入谷胱甘肽代谢途径。
T12189 NBDHEX

Apoptosis; Glutathione Peroxidase; Autophagy Apoptosis; Autophagy; Metabolism
NBDHEX 是一种谷胱甘肽 S-转移酶 P1-1 抑制剂,也是晚期自噬抑制剂。它诱导肿瘤细胞凋亡,通过抑制 GST 的催化活性,避免抑制剂被特异性泵从细胞中排出,以及破坏 GSTP1-1和关键信号传导因子之间的相互作用,从而起到抗癌的作用。
T11505 GSTO1-IN-1

Glutathione Peroxidase; GST Metabolism; oxidation-reduction
GSTO1-IN-1 是谷胱甘肽 S-转移酶 omega 1 抑制剂,IC50=31 nM。
T5463 Verdiperstat

AZD3241,AZD 3241

Glutathione Peroxidase Metabolism
Verdiperstat (AZD 3241) 是一种不可逆的、选择性的、口服具有活力的髓过氧化物酶 (myeloperoxidase) 抑制剂,IC50=630 nM,可用于研究大脑神经退行性疾病。
T10339 Antitrypanosomal agent 1

Parasite Microbiology/Virology
Antitrypanosomal agent 1 是一种有效的选择性锥虫硫酮还原酶抑制剂,IC50为 3.3 μM。它抑制谷胱甘肽还原酶,IC50为 64.8 μM,抑制布氏锥虫,EC50为 1 μM。
T8970 ML162

Ferroptosis; GPX; Glutathione Peroxidase Apoptosis; Metabolism; oxidation-reduction
ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 RAS 癌基因的细胞系。
T8452 Dantrolene

Others Others
Dantrolene 是一种肌肉松弛剂,是人红细胞谷胱甘肽还原酶的非竞争性抑制剂,其Ki 和IC50值分别为 111.6 μM 和 52.3 μM。它是兰尼碱受体拮抗剂及Ca2+信号稳定剂。它可用于研究恶性高热、亨廷顿病、肌肉痉挛和其他神经阻滞剂恶性综合征。
T21480 Diethylmaleate

Maleic acid, diethyl ester,DIETHYL MALEATE,马来酸二乙酯

NF-κB NF-κB
Diethylmaleate (Maleic acid, diethyl ester) 是马来酸二乙酯和一种抑制 NF-kB 的谷胱甘肽消耗化合物。
T4313 Tinoridine hydrochloride

盐酸替诺立定,Nonflamin,Y-3642 hydrochloride

COX; Glutathione Peroxidase Immunology/Inflammation; Metabolism; Neuroscience
Tinoridine hydrochloride (Y-3642 hydrochloride) 是非甾体抗炎药,具有显著的自由基清除和抗过氧化物特性。
T3646 RSL3

RSL3 1S,1S,3R-RSL3

Ferroptosis; GPX; Glutathione Peroxidase Apoptosis; Metabolism; oxidation-reduction
RSL3 (RSL3 1S) 是一种 GPX4 的抑制剂,抑制阻断 GSH 合成的 system xc- (IC50=100 nM)。RSL3 是一种不依赖 VDAC 的铁死亡激活剂,对携带致癌 RAS 的肿瘤细胞具有选择性。
T5097 Ezatiostat

TER199(free base),TLK199

Apoptosis; Glutathione Peroxidase; GST Apoptosis; Metabolism; oxidation-reduction
Ezatiostat (TER199(free base)) 是一种谷胱甘肽的三肽类似物,也是一种选择性的口服活性的谷胱甘肽 S-转移酶 P1-1 (GSTP1) 抑制剂。它通过抑制GSTP1导致 JNK 激活,刺激淋巴细胞生成和骨髓祖细胞增殖,可研究骨髓增生异常综合症。

化合物

Glutathione arsenoxide hydrochloride
Cat.No: T27417L
Synonym: GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)
Target: Apoptosis, AChR
Glutathione synthesis-IN-1
Cat.No: T9978
Synonym:
Target: Others
S-(4-Hydroxybenzyl)glutathione
Cat.No: TN7044
Synonym:
Target: GluR
S-Methylglutathione
Cat.No: T24807
Synonym: Glutathione S-methyl ester,Glutathione ester,S-Methyl glutathione
Target: Glyoxalase
Dansyl glutathione
Cat.No: T10956
Synonym: DNS-glutathione
Target: Others
S-Ethyl glutathione
Cat.No: T24782
Synonym: Glutathione monoethyl ester,Glutathione ethyl ester,L-gamma-Glutamyl-S-ethyl-L-cysteinylglycine
Target: Others
Glutathione sulfinanilide
Cat.No: T68833
Synonym:
Target: Others
Glutathione maleimide
Cat.No: T70831
Synonym:
Target: Others
Glutathione sodium
Cat.No: T69992
Synonym:
Target: Others
Glutathione sulfonate
Cat.No: T70331
Synonym:
Target: Others
L-Cysteine-glutathione disulfide
Cat.No: T38312
Synonym:
Target: Others
S-Acetyl-L-glutathione
Cat.No: T36073
Synonym:
Target: Others
Glutathione reductase
Cat.No: T78342
Synonym: EC 1.6.4.2
Target: Others
Glutathione arsenoxide
Cat.No: T27417
Synonym: GSAO
Target: Others
L-Glutathione, oxidized (sodium salt)
Cat.No: T36173
Synonym:
Target:
Glutathione glycylethyl ester
Cat.No: T70602
Synonym:
Target: Others
Glutathione amide
Cat.No: T31949
Synonym: GASH cpd,L-gamma-Glutamyl-L-cysteinylglycinamide
Target: Others
Nitrosoglutathione
Cat.No: T19930
Synonym: S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO
Target: RAAS, NO Synthase
Glutathione monoisopropyl ester
Cat.No: T31950
Synonym: YM737,YM 737,YM-737
Target: Others
Glutathione monoisopropyl ester acetate (97451-46-2 Free base)
Cat.No: T31950L
Synonym:
Target:
Glutathione palmitamide
Cat.No: T71441
Synonym:
Target: Others
Glutathione Peroxidase
Cat.No: T80056
Synonym: GSH-Px,EC 1.11.1.9
Target: Glutathione Peroxidase
Selenodiglutathione
Cat.No: T34605
Synonym: Seleno-di-glutathione,Bis(glutathione) selenide
Target: Others
Glutathione diethyl ester
Cat.No: T68202
Synonym:
Target:
Glutathione ethyl ester
Cat.No: T78616
Synonym:
Target: Reactive Oxygen Species
Darinaparsin
Cat.No: T35940
Synonym: Dimethylarsinic glutathione,Darinaparsin
Target: Others
GPX4 24
Cat.No: T83780
Synonym: Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24
Target: Others
S-(p-Nitrobenzyl)glutathione
Cat.No: T81233
Synonym:
Target: Others
S-Geranylgeranyl-L-glutathione
Cat.No: T83926
Synonym: GGG
Target: Others
S-(1,2-Dicarboxyethyl)glutathione
Cat.No: T81234
Synonym:
Target:
JKE-1674
Cat.No: T37314
Synonym:
Target: GPX
N,S-Bis-Fmoc-Glutathione
Cat.No: T80098
Synonym:
Target:
AZD5904
Cat.No: T14379
Synonym:
Target: Glutathione Peroxidase
Acifluorfen
Cat.No: T40588
Synonym:
Target: Others
MPO-IN-28
Cat.No: T5340
Synonym:
Target: Glutathione Peroxidase
ML-210
Cat.No: T8375
Synonym: CID 49766530
Target: Ferroptosis, GPX, Glutathione Peroxidase, Ras
TRi-1
Cat.No: T5481
Synonym:
Target: Others
PF-06282999
Cat.No: T4090
Synonym:
Target: Glutathione Peroxidase
Nitecapone
Cat.No: T7831
Synonym:
Target: Others, Transferase
N-Acetyl-D-cysteine
Cat.No: T38155
Synonym:
Target: Reactive Oxygen Species
NBDHEX
Cat.No: T12189
Synonym:
Target: Apoptosis, Glutathione Peroxidase, Autophagy
GSTO1-IN-1
Cat.No: T11505
Synonym:
Target: Glutathione Peroxidase, GST
Verdiperstat
Cat.No: T5463
Synonym: AZD3241,AZD 3241
Target: Glutathione Peroxidase
Antitrypanosomal agent 1
Cat.No: T10339
Synonym:
Target: Parasite
ML162
Cat.No: T8970
Synonym:
Target: Ferroptosis, GPX, Glutathione Peroxidase
Dantrolene
Cat.No: T8452
Synonym:
Target: Others
Diethylmaleate
Cat.No: T21480
Synonym: Maleic acid, diethyl ester,DIETHYL MALEATE,马来酸二乙酯
Target: NF-κB
Tinoridine hydrochloride
Cat.No: T4313
Synonym: 盐酸替诺立定,Nonflamin,Y-3642 hydrochloride
Target: COX, Glutathione Peroxidase
RSL3
Cat.No: T3646
Synonym: RSL3 1S,1S,3R-RSL3
Target: Ferroptosis, GPX, Glutathione Peroxidase
Ezatiostat
Cat.No: T5097
Synonym: TER199(free base),TLK199
Target: Apoptosis, Glutathione Peroxidase, GST
Cat. No. Product Name Target Signaling Pathways
T1085L Glutathione oxidized

Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG

Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Glutathione oxidized (L(-)-Glutathione) 是氧化型谷胱甘肽,谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。
T1085 L-Glutathione reduced

谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion

Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
L-Glutathione reduced (Glutathione) 属于天然三肽,存在与细胞中,是一种内源性抗氧化剂,可以清除氧自由基。L-Glutathione reduced 是某些酶的辅助因子,参与蛋白质二硫键重排并减少过氧化物。
TN1078 Seneciphylline

千里光菲灵碱,千里光非灵

P450; GST Metabolism; oxidation-reduction
Seneciphylline 是一种有毒的吡咯烷核生物碱,存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性,但导致细胞色素 P-450 和相关单加氧酶特性的抑制。
T3S0012 coniferyl ferulate

P-gp; GST Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
Coniferyl ferulate 是从川芎中提取的一种天然产物,是强效的谷胱甘肽 S-转移酶抑制剂,强抑制人胎盘型谷胱甘肽 S-转移酶,IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
T5372 L-SelenoMethionine

L-(+)-Selenomethionine,L-硒代蛋氨酸

Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite Apoptosis; Metabolism
L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体,是硒的主要天然食物形式。它是一种癌症化学预防剂,可以增加谷胱甘肽过氧化物酶的表达,还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。
T2O2721 L-Cysteine

Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine

Endogenous Metabolite Metabolism
L-Cysteine (L-(+)-Cysteine) 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。
T2800 L-Theanine

L-茶氨酸,左旋茶氨酸

Apoptosis; Others Apoptosis; Others
L-Theanine 是一种存在于绿茶叶片中的非蛋白氨基酸物质,能阻断大脑中谷氨酸与谷氨酸受体结合,具有神经保护和抗氧化活性。 它通过口服能抑制皮层神经元兴奋从而产生抗应激作用。
TJS0338 4-Methylesculetin

4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭

Antioxidant; Glutathione Peroxidase Metabolism; oxidation-reduction
4-Methylesculetin (Methylesculetin) 是口服具有活力的天然香豆素衍生物,有抗氧化、抗炎特性。它可抑制myeloperoxidase 的特性,抑制 IL-6 的水平
T7995 α-Angelica lactone

α-当归内酯,当归内酯,Alpha-Angelica Lactone

Others; GST Others; oxidation-reduction
α-Angelica lactone 是一种乙烯基亲核试剂,也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ,γ-二取代丁烯醇内酯羰基衍生物,并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。
T3S0541 Curzerene

莪术烯,莪术呋喃烯

Apoptosis; GST Apoptosis; oxidation-reduction
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutathione S-transferase A1 (GSTA1) mRNA and protein.
TN7107 S-(2-Carboxypropyl)cysteine

Endogenous Metabolite Metabolism
S-(2-Carboxypropyl)cysteine 是 S-(2-Carboxypropyl)glutathione 的尿代谢产物。
T4818 Thyminose

2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose

Apoptosis; Others; Endogenous Metabolite Apoptosis; Metabolism; Others
Thyminose 通过抑制谷胱甘肽的合成和增加其外排诱导细胞凋亡。
T4879 12-Hydroxydodecanoic acid

12-hydroxylauric acid,12-羟基月桂酸

Others; Endogenous Metabolite Metabolism; Others
12-Hydroxydodecanoic acid (12-hydroxylauric acid) 是内源性代谢产物的一种。
TN2175 Salvianolic acid F

丹酚酸F,丹酚酸 F

Caspase Apoptosis; Proteases/Proteasome
The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6.
TJS1382 Taraxerone

蒲公英赛酮

Dehydrogenase Metabolism
Taraxerone 是分离自景天的天然产物。它可以增强乙醇脱氢酶和乙醛脱氢酶活性,EC50分别为 512.42 μM 和 500.16 μM。
T19117 3-Deoxyglucosone

3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

GPX; Glucagon Receptor GPCR/G Protein; oxidation-reduction
3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活,可与低葡萄糖协同作用以增强 GLP-1 分泌,可以作为糖尿病生物学检测的标志物。
T0507 L-Pyroglutamic acid

L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline

Others; Endogenous Metabolite Metabolism; Others
L-Pyroglutamic acid (pidolic acid) 是 Pyroglutamic acid 的左旋异构体,是人体中具有生物特性的对映异构体。Pyroglutamic acid 是谷胱甘肽代谢中的中间体。
T5654 Musk ketone

Others Others
Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性,因此可能被证明是有用的癌症化学保护剂。
T30451 Biliatresone

Others Others
Biliatresone 是一种从球藻 Dysphania glomulifera 和 D. littoralis 中分离出来的环境毒素,诱导 C57BL/6J 新生儿胆管病,诱导谷胱甘肽 (GSH) 水平降低,诱导 SOX17 胆管细胞水平显着降低,诱导小鼠肝外胆管细胞损伤和纤维化。
T11680 Isoasatone A

P450 Metabolism
Isoasatone A 是一种具有抗虫作用的天然产物,分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶,产生抗S. litura 作用。
T3S0218 Thonningianin A

Apoptosis; Others Apoptosis; Others
Thonningianin A 是从非洲草药通宁宁的甲醇提取物中,分离得到的一种鞣花素,具有抗癌和抗氧化性,涉及自由基清除、抗超氧化物形成和金属螯合。
T2S1778 DL-Goitrin

DL-甲状腺肿素,板蓝根,Goitrin,(R,S)-告依春

Others Others
DL-Goitrin 也称为 (R,S)-Goitrin,由 epigoitrin (R-Goitrin) 和告依春 (S-Goitrin) 两种异构体组成,是板蓝根的成分。
TN5283 L-Cysteine hydrochloride hydrate

L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐 一水合物

Others; Endogenous Metabolite Metabolism; Others
L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) 是条件必需氨基酸,是硫化氢、谷胱甘肽和牛磺酸等生物活性分子的前体。它可以抑制胃饥饿素,抑制啮齿动物和人类的食欲。
T2S0618 β-Elemonic Acid

3-oxo Tirucallic Acid,β-岚香酮酸,Beta-Elemonic acid,3-Oxotirucallenoic Acid,β-榄香酮酸,Elemadienonic Acid

Apoptosis; Reactive Oxygen Species; COX Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
β-Elemonic Acid (3-Oxotirucallenoic Acid) 是从乳香树中分离得到的一种三萜,具有抗癌和抗炎作用。它抑制脯氨酰内肽酶,诱导细胞凋亡,活性氧和COX-2表达。
T6S0071 Fraxinellone

HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物,是PD-L1抑制剂,可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1,有用于癌症免疫的潜力。
T2823 Crocin

西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素

Others Others
Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。
TN5538 6-Methoxykaempferol

Others Others
6-Methoxykaempferol 是一种存在于 brazilian propolis 中的黄酮。6-Methoxykaempferol 对癌细胞具有抗增殖活性,对离体大鼠脑突触体的神经保护作用,可降低的谷胱甘肽水平。6-Methoxykaempferol 表现出一定的脂肪酶活性,可用于恶病质的治疗。
TN5166 Trans-Methylisoeugenol

Parasite; GST Microbiology/Virology; oxidation-reduction
Trans-Methylisoeugenol 是从 Acorus calamus L 中分离得到的具有杀虫活性的化合物。它 是一种天然食用香料,具有抗焦虑和抗抑郁等特性,可对谷胱甘肽 S-转移酶(GSTs)产生中度可逆性抑制作用(对人类 GSTs 的抑制浓度为 0.2 至 5.4 毫摩尔,对大鼠 GSTs 的抑制浓度为 0.4 至 4.9 毫摩尔)。
T4918 DL-Glyceraldehyde

Glyceric aldehyde,DL-甘油醛晶体

Reductase Endocrinology/Hormones; Metabolism
DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的,该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物,可以修饰和交联蛋白质。
TN7281 Bequinostatin A

Others Others
Glutathione S-Transferase (GST) π-class inhibitor acts to inhibit a specific class within the GST enzyme family, targeting the π variant. This compound selectively blocks the activity of this enzyme, which plays a critical role in the detoxification of compounds by catalyzing their conjugation with glutathione.
TN4318 Isophysalin A

IκB/IKK NF-κB
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production inhibiting activities.
TN7282 Bequinostatin C

Others Others
Glutathione S-Transferase (GST) π class inhibitor is a chemical compound designed to inhibit the action of the π class of GST enzymes.
TN2849 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

Antifection Microbiology/Virology
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities.
TN4345 Jacobine

Others Others
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.
T5S0313 Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside

Liquiritin apioside,甘草苷元-7-O-D-芹糖-4'-O-D-葡萄糖苷

Others; TNF Apoptosis; Others
Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as protective agent against epithelial
TN2006 Odoriflavene

Others Others
Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in vitro.
T82046 Irisquinone

Irisquinone,一种具有抗癌活性的天然产物,同时作为癌症放射增敏剂。该化合物通过降低GSH水平并抑制DNA单链断裂修复,展现其药理作用。
TN3735 Cycloart-23-ene-3,25-diol

Antifection Microbiology/Virology
Cycloart-23-ene-3,25-diol has anti-inflammatory activity, it has protective activity against streptozotocin induced toxicity. Cycloart-23-ene-3,25-diol treatment can decrease liver malondialdehyde but increase superoxidase dismutase and reduced glutathion
TN2876 3,4-Dihydroxy-2-methoxyxanthone

Antibacterial; Antifection Microbiology/Virology
3,4-Dihydroxy-2-methoxyxanthone 显示出抗菌和保肝活性,它能防止叔丁基过氧化氢诱导的新鲜离体大鼠肝细胞的脂质过氧化和细胞死亡,并在一定程度上有效防止细胞谷胱甘肽平衡的扰乱。
T37714 Fuscin

Others Others
Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-...
T35770 Cylindrospermopsin

Others Others
Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...
T36448 (E)-Ajoene

Others Others
(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T83915 Norbixin hydrate

Others Others
Norbixin是一种在B. orellana中发现的类胡萝卜素,具有多样的生物活性。在无细胞测试中,它与过氧化物酶体增殖物激活受体γ (PPARγ)结合(Ki = 1.15 µM)。在心脑血管代谢综合征大鼠模型中,Norbixin (47.7 mg/kg) 能够减轻高血糖、高胰岛素血症和胰岛素抗性,降低血清脂质水平及心脏中硫代巴比妥酸反应性物质(TBARS)和谷胱甘肽(GSH)的水平。在胆固醇诱导的动脉粥样硬化兔模型中,它降低氧化型LDL和主动脉蛋白氧化水平,并减少动脉粥样硬化面积。Norbixin(每天0.1和1 mg/kg)减少汞诱导的大鼠肝细胞和白细胞DNA损伤。此外,它还能预防与年龄相关的黄斑变性(AMD)Abca4-/- Rdh8-/-小鼠模型中的光感受器退化。

天然产物

Glutathione oxidized
Cat.No: T1085L
Synonym: Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG
Target: Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase
L-Glutathione reduced
Cat.No: T1085
Synonym: 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion
Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase
Seneciphylline
Cat.No: TN1078
Synonym: 千里光菲灵碱,千里光非灵
Target: P450, GST
coniferyl ferulate
Cat.No: T3S0012
Synonym:
Target: P-gp, GST
L-SelenoMethionine
Cat.No: T5372
Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸
Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite
L-Cysteine
Cat.No: T2O2721
Synonym: Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine
Target: Endogenous Metabolite
L-Theanine
Cat.No: T2800
Synonym: L-茶氨酸,左旋茶氨酸
Target: Apoptosis, Others
4-Methylesculetin
Cat.No: TJS0338
Synonym: 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭
Target: Antioxidant, Glutathione Peroxidase
α-Angelica lactone
Cat.No: T7995
Synonym: α-当归内酯,当归内酯,Alpha-Angelica Lactone
Target: Others, GST
Curzerene
Cat.No: T3S0541
Synonym: 莪术烯,莪术呋喃烯
Target: Apoptosis, GST
S-(2-Carboxypropyl)cysteine
Cat.No: TN7107
Synonym:
Target: Endogenous Metabolite
Thyminose
Cat.No: T4818
Synonym: 2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose
Target: Apoptosis, Others, Endogenous Metabolite
12-Hydroxydodecanoic acid
Cat.No: T4879
Synonym: 12-hydroxylauric acid,12-羟基月桂酸
Target: Others, Endogenous Metabolite
Salvianolic acid F
Cat.No: TN2175
Synonym: 丹酚酸F,丹酚酸 F
Target: Caspase
Taraxerone
Cat.No: TJS1382
Synonym: 蒲公英赛酮
Target: Dehydrogenase
3-Deoxyglucosone
Cat.No: T19117
Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose
Target: GPX, Glucagon Receptor
L-Pyroglutamic acid
Cat.No: T0507
Synonym: L-焦谷氨酸,pidolic acid,L-pyroglutamate,5-Oxoproline
Target: Others, Endogenous Metabolite
Musk ketone
Cat.No: T5654
Synonym:
Target: Others
Biliatresone
Cat.No: T30451
Synonym:
Target: Others
Isoasatone A
Cat.No: T11680
Synonym:
Target: P450
Thonningianin A
Cat.No: T3S0218
Synonym:
Target: Apoptosis, Others
DL-Goitrin
Cat.No: T2S1778
Synonym: DL-甲状腺肿素,板蓝根,Goitrin,(R,S)-告依春
Target: Others
L-Cysteine hydrochloride hydrate
Cat.No: TN5283
Synonym: L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐 一水合物
Target: Others, Endogenous Metabolite
β-Elemonic Acid
Cat.No: T2S0618
Synonym: 3-oxo Tirucallic Acid,β-岚香酮酸,Beta-Elemonic acid,3-Oxotirucallenoic Acid,β-榄香酮酸,Elemadienonic Acid
Target: Apoptosis, Reactive Oxygen Species, COX
Fraxinellone
Cat.No: T6S0071
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1
Crocin
Cat.No: T2823
Synonym: 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素
Target: Others
6-Methoxykaempferol
Cat.No: TN5538
Synonym:
Target: Others
Trans-Methylisoeugenol
Cat.No: TN5166
Synonym:
Target: Parasite, GST
DL-Glyceraldehyde
Cat.No: T4918
Synonym: Glyceric aldehyde,DL-甘油醛晶体
Target: Reductase
Bequinostatin A
Cat.No: TN7281
Synonym:
Target: Others
Isophysalin A
Cat.No: TN4318
Synonym:
Target: IκB/IKK
Bequinostatin C
Cat.No: TN7282
Synonym:
Target: Others
3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid
Cat.No: TN2849
Synonym:
Target: Antifection
Jacobine
Cat.No: TN4345
Synonym:
Target: Others
Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside
Cat.No: T5S0313
Synonym: Liquiritin apioside,甘草苷元-7-O-D-芹糖-4'-O-D-葡萄糖苷
Target: Others, TNF
Odoriflavene
Cat.No: TN2006
Synonym:
Target: Others
Irisquinone
Cat.No: T82046
Synonym:
Target:
Cycloart-23-ene-3,25-diol
Cat.No: TN3735
Synonym:
Target: Antifection
3,4-Dihydroxy-2-methoxyxanthone
Cat.No: TN2876
Synonym:
Target: Antibacterial, Antifection
Fuscin
Cat.No: T37714
Synonym:
Target: Others
Cylindrospermopsin
Cat.No: T35770
Synonym:
Target: Others
(E)-Ajoene
Cat.No: T36448
Synonym:
Target: Others
Norbixin hydrate
Cat.No: T83915
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferase alpha 1,GTH1,GST2,glu...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPJ-00979 GSH-S Protein, Human, Recombinant (His)

Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,

Human E. coli
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...
TMPH-03108 GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)

GPX5,Glutathione peroxidase 5,Epididymis-specific <...

Sus scrofa (Pig) E. coli
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPH-01296 GPX5 Protein, Human, Recombinant (GST & His)

GPX5,Glutathione peroxidase 5,Epididymal secretory ...

Human E. coli
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
TMPH-03109 GPX5 Protein, Pig, Recombinant (His & Myc)

GPX5,Epididymis-specific glutathione peroxidase-lik...

Sus scrofa (Pig) P. pastoris (Yeast)
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPH-02681 GPX7 Protein, Mouse, Recombinant (His & Myc)

Glutathione peroxidase 7,Gpx7

Mouse E. coli
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. GPX7 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q99LJ6.
TMPH-03443 GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

Glutathione peroxidase homolog 2,Glutathione

Saccharomyces cerevisiae E. coli
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation. GPX2 Protein, ...
TMPY-03450 GSTK1 Protein, Human, Recombinant

glutathione S-transferase κ1,GST,glutathione

Human E. coli
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the...
TMPY-03338 GSTZ1 Protein, Human, Recombinant (His)

MAI,GSTZ1-1,glutathione S-transferase ζ 1,MAAI,GSTZ...

Human E. coli
GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid ...
TMPY-00027 GSTT2B Protein, Human, Recombinant (His)

GSTT2P,glutathione S-transferase θ 2B (gene/pseudog...

Human HEK293 Cells
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29.
TMPH-02682 GSTM3 Protein, Mouse, Recombinant (His & Myc)

GST class-mu 3,Gstm3,Glutathione S-transferase Mu 3...

Mouse E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GSTM3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is P19639.
TMPH-01396 GSTK1 Protein, Human, Recombinant (GST)

GSTK1,Glutathione S-transferase kappa 1,Glutath...

Human E. coli
Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB). GSTK1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.4 kDa and the accession number is Q9Y2Q3.
TMPH-00073 ADH2 Protein, Arabidopsis thaliana, Recombinant (His)

GSH-FDH,Glutathione-dependent formaldehyde dehydrog...

Arabidopsis thaliana E. coli
Plays a central role in formaldehyde detoxification. ADH2 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.7 kDa and the accession number is Q96533.
TMPJ-00690 PGDS Protein, Human, Recombinant

Glutathione-Requiring Prostaglandin D Synthase,PGDS...

Human E. coli
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydrop...
TMPY-01554 GSTM5 Protein, Human, Recombinant (His)

GSTM5-5,glutathione S-transferase mu 5,GTM5,GSTM5

Human E. coli
GSTM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.9 kDa and the accession number is AAH58881.1.
TMPH-01399 GSTP1 Protein, Human, Recombinant (His)

GST class-pi,GSTP1,Glutathione S-transferase P,GSTP...

Human P. pastoris (Yeast)
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.2 kDa and...
TMPH-00444 GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)

GST class-pi,GSTP1,Glutathione S-transferase P

Chinese hamster E. coli
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00445 GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)

Glutathione S-transferase P,GST class-pi,GSTP1

Chinese hamster P. pastoris (Yeast)
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His) is expressed in Yeast.
TMPY-02223 GSTM2 Protein, Human, Recombinant (His)

GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (musc...

Human E. coli
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...
TMPJ-00499 GSTP1 Protein, Human, Recombinant

GSTP1,GST3,GST class-pi,Glutathione S-transferase P...

Human E. coli
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione ...
TMPH-01398 GSTP1 Protein, Human, Recombinant (E. coli, His)

GSTP1,Glutathione S-transferase P,GSTP1-1,GST class...

Human E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mo...
TMPY-02843 GPX7 Protein, Human, Recombinant (hFc)

GSHPx-7,UNQ469/PRO828,NPGPx,CL683,glutathione perox...

Human HEK293 Cells
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by overlapping exons with different boundaries. GPX7 is an enzyme. It has molecular functions (glutathione peroxidase activity, oxidoreductase activity) and to localize in various compartments (extracellular space, extracellular region). GPX7 gene has been proposed to part...
TMPH-00912 ADH5 Protein, Human, Recombinant (GST)

Alcohol dehydrogenase class-III,Alcohol dehydrogenase 5,S-(h...

Human E. coli
ADH5 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-03305 GSTA1 Protein, Rat, Recombinant (His & SUMO)

Androst-5-ene-3,17-dione isomerase,GST 1-1,13-hydroperoxyoct...

Rat E. coli
GSTA1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01397 LANCL1 Protein, Human, Recombinant (His & Myc)

LANCL1,40 kDa erythrocyte membrane protein,Glutathione

Human E. coli
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. LANCL1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc...
TMPH-03306 GSTP1 Protein, Rat, Recombinant (His)

Chain 7,Glutathione S-transferase P,GST 7-7,GST cla...

Rat E. coli
GSTP1 Protein, Rat, Recombinant (His) is expressed in E. coli.
TMPH-02683 GSTP1 Protein, Mouse, Recombinant (His & SUMO)

Gstp1,GST-piB,GST class-pi,Preadipocyte growth factor,GST YF...

Mouse E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
TMPH-01711 ABCC1 Protein, Human, Recombinant (His)

MRP,ATP-binding cassette sub-family C member 1,Leukotriene C...

Human E. coli
ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
TMPH-01601 Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant (GST)

Ketone-aldehyde mutase,Glyoxalase I,Lactoylglutathione

Human E. coli
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.
TMPY-02157 GST Protein, Schistosoma japonicum, Recombinant

Schistosoma japonicum Baculovirus Insect Cells
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated into an expression vector alongside the gene sequence encoding the protein of interest. Induction of protein expression from the vector's promoter results in expression of a fusion protein: the protein of interest fused to the GST protein. This GST-fusion protein can then be purifie...
TMPH-01511 GLO2 Protein, Human, Recombinant (GST)

Glyoxalase II,Hydroxyacylglutathione hydrolase, mit...

Human E. coli
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
TMPY-03605 Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His)

GLRX,GRX,GRX1,glutaredoxin

Human E. coli
Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. Glutaredoxin-1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. Glutaredoxin-1 exists in either a reduced or an oxidized form. Glutaredoxins function as electron carriers ...
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His)

HAGH1,GLO2,GLX2,hydroxyacylglutathione hydrolase,GL...

Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio...
TMPY-03412 GGCT Protein, Human, Recombinant (His)

gamma-glutamylcyclotransferase,C7orf24,GGC,γ-glutamylcyclotr...

Human E. coli
GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants...
TMPH-03138 GST Protein, Plasmodium falciparum, Recombinant (His)

Plasmodium falciparum P. pastoris (Yeast)
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). GST Protein, Plasmodium falciparum, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 27.3 kDa and the accession number is Q8MU52.
TMPY-02201 Peroxiredoxin 6 Protein, Human, Recombinant (His)

p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2,aiPLA2

Human E. coli
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities,which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPJ-00946 TALDO1 Protein, Human, Recombinant (His)

Transaldolase,TALDO1,TAL,TALDOR,TALDO

Human HEK293 Cells
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the sk...
TMPY-01480 LTC4S Protein, Human, Recombinant (His)

LTC4S,MGC33147,leukotriene C4 synthase

Human Baculovirus Insect Cells
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells, and platelets. LTC4S is essential for the production of cysteinyl leukotrienes (Cys...
TMPJ-01142 CDO1 Protein, Human, Recombinant (His)

CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cysteine Dioxygen...

Human E. coli
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c...
TMPY-04022 BOLA1 Protein, Human, Recombinant (His)

CGI-143,bolA family member 1

Human E. coli
BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA1 nullifies the effect of BSO and S-nitrosocysteine on mitochondrial morphology. Conversely, knockdown of the BOLA1 gene increases the oxidation of mitochondrial thiol groups. Supporting a role of BOLA1 in controlling the mitochondrial thiol redox potential is that BOLA1 ortholog...
TMPJ-00836 G6PD Protein, Human, Recombinant (His)

Glucose-6-Phosphate 1-Dehydrogenase,G6PD

Human HEK293 Cells
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the re...
TMPY-01618 GLO1 Protein, Mouse, Recombinant (His)

glyoxalase I,Glo-1r,GLY1,Glo1-r,2510049H23Rik,Glo1-s,AW55064...

Mouse E. coli
Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellul...
TMPH-01503 Humanin Protein, Human, Recombinant (hFc)

MT-RNR2,Humanin,Humanin mitochondrial

Human HEK293 Cells
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPH-01502 Humanin Protein, Human, Recombinant (GST)

Humanin,Humanin mitochondrial,MT-RNR2

Human E. coli
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....

重组蛋白

GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
GSH-S Protein, Human, Recombinant (His)
Cat.No: TMPJ-00979
Species: Human
Expression System: E. coli
GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03108
Species: Sus scrofa (Pig)
Expression System: E. coli
GPX5 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01296
Species: Human
Expression System: E. coli
GPX5 Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03109
Species: Sus scrofa (Pig)
Expression System: P. pastoris (Yeast)
GPX7 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02681
Species: Mouse
Expression System: E. coli
GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)
Cat.No: TMPH-03443
Species: Saccharomyces cerevisiae
Expression System: E. coli
GSTK1 Protein, Human, Recombinant
Cat.No: TMPY-03450
Species: Human
Expression System: E. coli
GSTZ1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03338
Species: Human
Expression System: E. coli
GSTT2B Protein, Human, Recombinant (His)
Cat.No: TMPY-00027
Species: Human
Expression System: HEK293 Cells
GSTM3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02682
Species: Mouse
Expression System: E. coli
GSTK1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01396
Species: Human
Expression System: E. coli
ADH2 Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00073
Species: Arabidopsis thaliana
Expression System: E. coli
PGDS Protein, Human, Recombinant
Cat.No: TMPJ-00690
Species: Human
Expression System: E. coli
GSTM5 Protein, Human, Recombinant (His)
Cat.No: TMPY-01554
Species: Human
Expression System: E. coli
GSTP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01399
Species: Human
Expression System: P. pastoris (Yeast)
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)
Cat.No: TMPH-00444
Species: Chinese hamster
Expression System: E. coli
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)
Cat.No: TMPH-00445
Species: Chinese hamster
Expression System: P. pastoris (Yeast)
GSTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02223
Species: Human
Expression System: E. coli
GSTP1 Protein, Human, Recombinant
Cat.No: TMPJ-00499
Species: Human
Expression System: E. coli
GSTP1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01398
Species: Human
Expression System: E. coli
GPX7 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02843
Species: Human
Expression System: HEK293 Cells
ADH5 Protein, Human, Recombinant (GST)
Cat.No: TMPH-00912
Species: Human
Expression System: E. coli
GSTA1 Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03305
Species: Rat
Expression System: E. coli
LANCL1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01397
Species: Human
Expression System: E. coli
GSTP1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03306
Species: Rat
Expression System: E. coli
GSTP1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02683
Species: Mouse
Expression System: E. coli
ABCC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01711
Species: Human
Expression System: E. coli
Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01601
Species: Human
Expression System: E. coli
GST Protein, Schistosoma japonicum, Recombinant
Cat.No: TMPY-02157
Species: Schistosoma japonicum
Expression System: Baculovirus Insect Cells
GLO2 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01511
Species: Human
Expression System: E. coli
Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03605
Species: Human
Expression System: E. coli
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
Cat.No: TMPY-02288
Species: Human
Expression System: E. coli
GGCT Protein, Human, Recombinant (His)
Cat.No: TMPY-03412
Species: Human
Expression System: E. coli
GST Protein, Plasmodium falciparum, Recombinant (His)
Cat.No: TMPH-03138
Species: Plasmodium falciparum
Expression System: P. pastoris (Yeast)
Peroxiredoxin 6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02201
Species: Human
Expression System: E. coli
TALDO1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00946
Species: Human
Expression System: HEK293 Cells
LTC4S Protein, Human, Recombinant (His)
Cat.No: TMPY-01480
Species: Human
Expression System: Baculovirus Insect Cells
CDO1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01142
Species: Human
Expression System: E. coli
BOLA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04022
Species: Human
Expression System: E. coli
G6PD Protein, Human, Recombinant (His)
Cat.No: TMPJ-00836
Species: Human
Expression System: HEK293 Cells
GLO1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01618
Species: Mouse
Expression System: E. coli
Humanin Protein, Human, Recombinant (hFc)
Cat.No: TMPH-01503
Species: Human
Expression System: HEK293 Cells
Humanin Protein, Human, Recombinant (GST)
Cat.No: TMPH-01502
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMIJ-0165 Glutathione-(glyucine-13C2-15N) Trifluoroacetate

Glutathione-(glyucine-13C2-15N) Trifluoroacetate 是 Glutathione Trifluoroacetate 的 13C 和 15 N 的标记化合物。
T11240 Ethacrynic acid D5

Others Others
Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by...
TMIJ-0342 Aniline-d5

Aniline-d5 是 Aniline 的氘代化合物。Aniline 的 CAS 号为 62-53-3。Aniline 通过铁过载和通过血红素加氧酶 1 上调诱导氧化应激对脾脏产生毒性。它会导致 p-IKKα 和 p-IKKβ 显着增加,进而增加 NF-κB 和 AP-1 结合活性。
TMIJ-0384 L-Cysteine-d3

L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。

同位素标记化合物

Glutathione-(glyucine-13C2-15N) Trifluoroacetate
Cat.No: TMIJ-0165
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Ethacrynic acid D5
Cat.No: T11240
Synonym:
Target: Others
Aniline-d5
Cat.No: TMIJ-0342
Synonym:
Target:
L-Cysteine-d3
Cat.No: TMIJ-0384
Synonym:
Target:
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