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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3160 |
HUHS015
|
Others | Others |
HUHS015 是高效的PCA-1/ALKBH3抑制剂。它对 PCA-1 作用的IC50值为 0.67 μM。 | |||
T8995 |
NCGC00262650
|
Others; Src | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
NCGC00262650 是 AMA1-RON2 相互作用和 c-Src 酪氨酸激酶活性的抑制剂。 | |||
T2051 |
SKLB4771
FLT3-IN-1,FLT3-IN-1 |
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
SKLB4771 (FLT3-IN-1) 是一种新型的、高效的 Flt3 抑制剂 (IC50:10nM)。 | |||
T9027 |
CA-4948
Emavusertib |
IRAK; FLT | Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors |
CA-4948 (Emavusertib) 是一种IRAK4抑制剂,也是一种FLT3抑制剂,具有抗肿瘤作用。 | |||
T6289 |
Dovitinib
TKI258,多韦替尼,CHIR-258,度维替尼 |
VEGFR; FGFR; FLT; PDGFR; c-Kit | Angiogenesis; Tyrosine Kinase/Adaptors |
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。 | |||
T5164 |
Cabozantinib hydrochloride
XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351,盐酸卡博替尼 |
VEGFR; FLT; c-Met/HGFR; TAM Receptor; c-Kit; ROR | Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors |
Cabozantinib hydrochloride (XL184) 是一种有效的泛酪氨酸激酶抑制剂,可抑制 VEGFR2、c-Met、Kit、Axl 和 Flt4(IC50:0.035、1.3、4.6、7 和 6 nM)。 | |||
T2514 |
Linifanib
利尼伐尼,ABT-869,RG3635,AL-39324 |
Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy | Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors |
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。 | |||
T6028 |
PF 477736
PF 00477736,PF-477736,PF-736,PF-00477736,PF477736 |
c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase | Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors |
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。 | |||
T4349 |
Sitravatinib
MG516,MGCD516 |
Discoidin Domain Receptor (DDR); VEGFR; FLT; Trk receptor; TAM Receptor; c-Kit; Ephrin Receptor | Angiogenesis; Tyrosine Kinase/Adaptors |
Sitravatinib (MGCD516) 是一种有口服活性的受体酪氨酸激酶抑制剂。它单独使用即具有有效的抗肿瘤功效,且通过促进抗肿瘤免疫微环境增强了 PD-1 阻断的活性。 | |||
T3977 |
Lifitegrast
SHP-606,SAR 1118,立他司特,利非司特 |
Integrin | Cytoskeletal Signaling |
Lifitegrast (SAR 1118) 是一种整合素淋巴细胞功能相关抗原 1 拮抗剂, 抑制 Jurkat T 细胞附着于ICAM-1的IC50为 2.98 nM。 | |||
T14676 |
BMS-688521
|
Integrin | Cytoskeletal Signaling |
BMS-688521 是一种具有口服活性和高效性的 LFA-1/ICAM 相互作用抑制剂,是白细胞功能相关抗原-1 (LFA-1) 的小分子拮抗剂,具有潜在的抗炎活性。 | |||
T3977L |
Lifitegrast sodium
SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra |
Others | Others |
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte function-associated antigen 1 and intercel | |||
TP1493L1 |
PSA1 141-150 acetate
PSA1 141-150 acetate(160215-60-1 free base) |
Others | Others |
PSA1 141-150 acetate 用于癌症实验的免疫治疗,它是一种前列腺特异性抗原 1 肽。 | |||
T21781 |
A-286982
|
Integrin | Cytoskeletal Signaling |
A 286982是高效的LFA-1/ICAM-1相互作用变构抑制剂,在LFA-1/ICAM-1结合和LFA-1介导的细胞粘附实验中,其IC50分别为44和35 nM。 | |||
T12783 |
RWJ 50271
|
Integrin | Cytoskeletal Signaling |
RWJ 50271 是具有口服活性的选择性LFA-1/ICAM-1相互作用抑制剂,抑制 LFA-1/ICAM-1 介导的细胞粘附,在细胞HL60中的IC50值为 5.0 μM。 | |||
T14333 |
Asoxime dichloride
Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate,Asoxime (dichloride),HI-6 |
AChR | Neuroscience |
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) 是乙酰胆碱受体 (AChRs) 拮抗剂,包括烟碱受体,α7 乙酰胆碱受体。Asoxime dichloride 参与调节免疫应答。Asoxime dichloride 可作为抗原使用,改善神经系统的免疫效果。 | |||
T35719 |
T2AA
T2AA,4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol,ZINC95605533 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) 是一种增殖细胞核抗原 (PCNA) 抑制剂,对 PCNA/PIP-box 肽相互作用的 IC50 为 1 μM。 T2AA 通过停止 DNA 复制叉和抑制 PCNA 与 DNA 聚合酶 δ 的相互作用来引起 DNA 复制压力并抑制癌细胞生长。 | |||
T63790 |
Cbl-b-IN-3
|
E1/E2/E3 Enzyme | Ubiquitination |
Cbl-b-IN-3是一种有效的casitas b 系淋巴瘤原癌基因-b (Cbl-b)抑制剂(ic50 < 1 nM)。Cbl-b 是一种环型E3泛素蛋白连接酶,与T 淋巴细胞激活阈值的设定有关。Cbl-b 以不依赖于蛋白水解的方式负调控p85,通过其E3泛素连接酶活性,参与了p85向CD28和T 细胞抗原受体ζ的募集,抑制PI3K 抑制了Cblb-/- t 细胞活化的增强。 | |||
T80552 |
Prostate Specific Antigen Substrate
|
||
Prostate Specific Antigen Substrate为前列腺特异性抗原(PSA)的荧光底物,专用于检测PSA的酶活性。 | |||
T14558 |
BI-1950
|
Integrin | Cytoskeletal Signaling |
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is an essential component in normal immune system function and a target for drug discovery[1]. | |||
T69203 |
HMR1031
|
Others | Others |
HMR1031 is a potent and specific integrin α4ß1 or very late antigen 4 (VLA-4) receptor antagonist which binds to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin. | |||
T81883 |
MAGE-3 Antigen (167-176) (human)
|
||
MAGE-3 Antigen (167-176) (human) 是一个由 MAGE-A3 编码并与 HLA-B44 抗原结合的人类抗原决定簇,包含8个氨基酸的多肽序列。 | |||
TP1493 |
PSA1 (141-150)
PSA1 141-150 |
||
This Prostate Specific Antigen 1 peptide was used in the immunotherapy of cancer experiments. | |||
T81627 |
Oberotatug
|
||
Oberotatug为针对淋巴细胞抗原LY75的人源化IgG1κ单克隆抗体。 | |||
T81103 |
SSA antigenic peptide
|
||
SSA antigenic peptide为Sjögren综合征相关抗原A(SSA)的成分,具有免疫活性的短肽链。 | |||
T76534 |
HBV Seq1 aa:18-27
|
||
HBVSeq1 aa:18-27 是乙型肝炎病毒 (HBV) 核心抗原 18-27 肽片段。 | |||
T80966 |
Topsalysin
PRX-302 |
||
Topsalysin为PSA激活的前体蛋白质,同时是与人前列腺特异性抗原融合的孔隙形成蛋白(合成原气溶素)。研究显示Topsalysin能够抑制小鼠模型中的肿瘤生长。 | |||
T76532 |
HBV Seq1 aa:93-100
|
||
HBVSeq1 aa:93-100 是乙型肝炎病毒 (HBV) 核心抗原 93-100 肽片段。 | |||
T35884 |
Sialyl-Lewis X
|
Others | Others |
Sialyl-Lewis X (sLeX), a sialylated fucosylated tetrasaccharide and endogenous antigen, serves as a high-affinity ligand for selectins (E-, P-, and L-selectin)[1]. It interacts with ELAM-1 and CD62, consequently inhibiting CD62-mediated neutrophil recruitment to inflammation sites[2]. | |||
T78285 |
Sofituzumab
MMUC 1206A |
||
Sofituzumab(MMUC 1206A)是一款针对MUC16的重组人源化V-kappa型单克隆抗体。 | |||
T38420 |
GCPII-IN-1
|
Others | Others |
GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM). | |||
T62921 |
EBNA1-IN-SC7
|
Others | Others |
EBNA1-IN-SC7 (compound SC7) 是一种 Epstein-Barr nuclear antigen 1 (EBNA1) 的选择性抑制剂,能够干扰 EBNA1-DNA 结合活性 (IC50: 23 μM)。EBNA1-IN-SC7 能够用于研究 EBV (Epstein-Barr virus) 相关癌症。 | |||
T64475 |
FMOC-L-THR
|
Others | Others |
FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a m... | |||
T81252 |
RTQLLWTPAAPTAMA TFA
|
||
RTQLLWTPAAPTAMA TFA为肽类抗原,用于免疫应答中的药物传递。 | |||
T82340 |
Ganglioside GM2
|
||
Ganglioside GM2为人类肿瘤抗原(OFA-I-1),亦是泰-萨克斯病中主要的溶酶体贮存化合物。 | |||
T82449 |
Eramkafusp Alfa
|
||
Eramkafusp Alfa为针对小鼠B淋巴细胞上CD20 (MS4A1) 抗原的人源化IgG1单克隆抗体。 | |||
T80209 |
Human membrane-bound PD-L1 polypeptide
|
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
Human membrane-bound PD-L1 polypeptide 作为抗原,可诱导生成相应的PD-L1抗体。 | |||
T78298 |
Alefacept
LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273 |
||
Alefacept (BG 9273)为一种人类淋巴细胞功能相关抗原3/免疫球蛋白1融合蛋白,主要在慢性斑块状银屑病研究中使用。 | |||
TP1268 |
CEF19, Epstein-Barr Virus latent NA-3A (458-466)
CEF19,Epstein-Barr Virus latent NA-3A 458-466 |
||
CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). | |||
T76966 | Ublituximab | ||
Ublituximab (LFB-R603; TG-1101; TGTX-1101) 为针对CD20抗原特异表位的第一代嵌合型单克隆抗体,展现出抗癌活性。 | |||
T36412 |
Multiflorenol
|
Others | Others |
Multiflorenol is a triterpene that has been found in T. kirilowii seeds.1 It inhibits in vitro activation of Epstein-Barr virus early antigen (EBV-EA) induced by the tumor promoter phorbol 12-myristate 13-acetate in a concentration-dependent manner. |1. Akihisa, T., Tokuda, H., Ichiishi, E., et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer Lett. 173(1), 9-14 (2001). | |||
T78121 |
SSM3 tetraTFA hydrate
|
Others | Others |
SSM3 tetraTFA hydrate为有效的furin抑制剂,具有54 nM的EC50和12 nM的Ki。该化合物可有效阻断furin依赖的炭疽毒素保护antigen-83在细胞表面的处理。 | |||
TP1743 |
MPG, HIV related
|
||
MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells. | |||
T62434 |
HBV-IN-10
|
Others | Others |
HBV-IN-10 是一种 compound 6 (WO2021204258A1) 的异构体。其中 Compound 6 是一种乙型肝炎表面抗原 (HBsAg) 的有效抑制剂 (0.1 μM< EC50≤1 μM)。 | |||
T76529 |
HBV Seq2 aa:28-39
|
||
HBVSeq2 aa:28-39 是一种 HBsAg 肽,可与主要组织相容性复合体 (MHC) I 类分子结合。 | |||
T76015 |
HPV16 E7 (86-93) (TFA)
|
||
HPV16 E7 (86-93) TFA,一种HLA-A2.1限制的HPV16 E7衍生肽,在宫颈癌中显示出免疫原性。 | |||
T76835 | Tositumomab | ||
Tositumomab 是一种靶向CD20抗原的小鼠IgG2a lambda 单克隆抗体,CD20抗原存在于正常和恶性B 淋巴细胞表面。 | |||
T80875 |
Vatelizumab
GBR500 |
||
Vatelizumab (GBR500)为靶向VLA-2(极晚期抗原2)α2亚基(CD49b)的单克隆抗体,适用于多发性硬化症研究。 | |||
T62433 |
(5S,8R)-HBV-IN-10
|
Others | Others |
(5S,8R)-HBV-IN-10 是一种 compound 6 (WO2021204258A1) 的异构体。其中 Compound 6 是一种乙型肝炎表面抗原 (HBsAg) 的有效抑制剂 (0.1 μM< EC50≤1 μM)。 | |||
T79707 |
Cholicamideβ
|
Necroptosis | Apoptosis |
Cholicamideβ(compound 6)为自组装小分子癌症疫苗佐剂,能够形成细胞毒性低的病毒样颗粒。该化合物与肽抗原结合,可增强树突状细胞的抗原呈递能力,并激活抗原特异性T细胞反应。Cholicamideβ还能引发细胞凋亡(apoptosis)和坏死(necrosis)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79975 |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside
|
HBV | Microbiology/Virology |
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside(化合物1)是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原(HBsAg)的IC50为0.58 mM,而对HBV e抗原(HBeAg)的IC50 > 2.4 mM。其可从八角茴香中提取分离。 | |||
T81813 |
Methyl lucidenate Q
|
||
Methyl lucidenate Q,一种灵芝甲酯,展现了显著的抑制作用于EBV-EA诱导活性。 | |||
T79976 |
Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside
|
HBV | Microbiology/Virology |
Dihydrodehydrodiconiferyl alcohol 9-O-β-D-xylopyranoside 作为一种抗HBV剂,在Hep G2.2.15细胞系上能够抑制HBsAg和HBeAg的分泌,其IC50值分别约为1.67 mM和>2.15 mM。 | |||
T14368 |
Azadirachtin B
|
Others | Others |
Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3]. | |||
T38838 |
QS-21
Stimulon,QS-21 |
Others | Others |
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1. | |||
T82855 |
Blood group A pentasaccharide
A-Pentasaccharide |
||
A-Pentasaccharide 是一种尿液中的寡糖,具有抑制抗 A 抗体与 A 型血物质结合的功能。 | |||
T82856 |
Blood group A antigen tetraose type 5
A-Tetrasaccharide |
||
Blood group A antigen tetraose type 5 (A-Tetrasaccharide) 是特定于A型血的四糖,具有阻止抗-A抗体与A型血物质结合的能力。该化合物可通过北极熊乳样本纯化获得。 | |||
TN3736 | Cycloart-25-ene-3,24-diol | Others | Others |
(24R)-Cycloart-25-ene-3beta,24-diol may be an anti-tumor promoter, it exhibits inhibitory effects on both Epstein-Barr virus early antigen (EBV-EA) and (+/-)-(E)-methtyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3- hexemide (NOR 1) activation. | |||
T75567 |
Cabenoside D
|
Others | Others |
Cabenoside D(化合物 8)是从苔藓根的甲醇提取物中分离的一种三萜苷,显示出对12-O-十四烷酰基激素-13-乙酸酯(TPA)诱导的小鼠炎症的抗炎活性,并能抑制TPA促使的Epstein-Barr病毒(EBV)早期抗原(EBV-EA)激活。 | |||
T79977 |
Maceneolignan A
|
Others | Others |
Maceneolignan A,一种可从肉豆蔻(肉豆蔻科)假种皮分离的天然产品,有能力抑制RBL-2H3细胞内β-己糖胺酶释放,其IC50值为48.4 μM。同样,Maceneolignan A对抗原激活的RBL-2H3细胞中TNF-α释放的抑制作用,其IC50为63.7 μM。 | |||
T75566 |
11-Oxomogroside II A1
|
Others | Others |
11-Oxomogroside II A1(化合物 7)是一种从罗汉果乙醇提取物中分离的氧化葫芦苷,对12-O-十四烷酰基激素-13-乙酸酯(TPA)诱导的Epstein-Barr病毒(EBV)早期抗原(EBV-EA)活化具有抑制效果,并对一氧化氮(NO)供体(+/-)-(E)-甲基-2-[(E)羟基亚氨基]-5-硝基-6-甲氧基-3-己酰胺(NOR 1)的活化也展示出轻微的抑制作用。 | |||
T37272 |
9(S),12(S),13(S)-TriHOME
|
Others | Others |
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04123 |
CEACAM1 Protein, Human, Recombinant (His & hFc)
CEACAM‑1,carcinoembryonic antigen-related ... |
Human | HEK293 Cells |
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8. | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-00381 |
PSMA Protein, Human, Recombinant (His)
FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (prostate-sp... |
Human | HEK293 Cells |
PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1. | |||
TMPJ-00147 |
FOLR1 Protein, Human, Recombinant (hFc)
Folate receptor 1,Folate receptor,Folate receptor a... |
Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPY-00476 |
ITGB1 Protein, Human, Recombinant (His)
VLAB,integrin, beta 1 (fibronectin receptor, beta p... |
Human | HEK293 Cells |
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe... | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC11987... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPY-03737 |
Thy1/CD90 Protein, Cynomolgus, Recombinant (His)
Thy-1 cell surface antigen |
Cynomolgus | HEK293 Cells |
Thy1/CD90 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.9 kDa. | |||
TMPH-01654 |
MAGEA1 Protein, Human, Recombinant (His)
Antigen MZ2-E,MAGE-1 antigen,Canc... |
Human | P. pastoris (Yeast) |
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.3 kDa and the accession number... | |||
TMPY-03165 |
Thy1/CD90 Protein, Rat, Recombinant (His)
Thy-1 cell surface antigen |
Rat | HEK293 Cells |
Thy1/CD90 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.1 kDa and the accession number is P01830. | |||
TMPJ-00130 |
SLAMF2 Protein, Human, Recombinant (hFc & His)
Leukocyte antigen MEM-102,CD48 antigen... |
Human | HEK293 Cells |
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cel... | |||
TMPY-03038 |
CD157 Protein, Rat, Recombinant (His)
bone marrow stromal cell antigen 1 |
Rat | HEK293 Cells |
CD157 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is Q63072. | |||
TMPY-00878 |
MD1 Protein, Mouse, Recombinant (His)
lymphocyte antigen 86,MD-1,MD1 |
Mouse | HEK293 Cells |
MD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is O88188. | |||
TMPY-03037 |
CD157 Protein, Rat, Recombinant (hFc)
bone marrow stromal cell antigen 1 |
Rat | HEK293 Cells |
CD157 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q63072. | |||
TMPH-02766 |
LY6E Protein, Mouse, Recombinant (B2M & His)
Thymic shared antigen 1,Stem cell anti... |
Mouse | E. coli |
LY6E Protein, Mouse, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPY-04674 |
Thy1/CD90 Protein, Human, Recombinant (hFc)
CD90,Thy-1 cell surface antigen |
Human | HEK293 Cells |
Thy1/CD90 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.3 kDa and the accession number is B0YJA4. | |||
TMPY-05087 |
Thy1/CD90 Protein, Human, Recombinant (His)
Thy-1 cell surface antigen,CD90 |
Human | HEK293 Cells |
Thy1/CD90 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is B0YJA4. | |||
TMPH-02767 |
LY6E Protein, Mouse, Recombinant (His & SUMO)
Ly6e,Lymphocyte antigen 6E,Stem cell antigen |
Mouse | P. pastoris (Yeast) |
LY6E Protein, Mouse, Recombinant (His & SUMO) is expressed in yeast with N-6xHis-SUMO tag. The predicted molecular weight is 24.8 kDa and the accession number is Q64253. | |||
TMPJ-00958 |
B7-1 Protein, Rabbit, Recombinant (His)
Activation B7-1 antigen,T-lymphocyte activ... |
Rabbit | HEK293 Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ... | |||
TMPJ-00632 |
B7-2 Protein, Cynomolgus, Recombinant (hFc)
T-lymphocyte activation antigen CD86 isoform 1<... |
Cynomolgus | HEK293 Cells |
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4. | |||
TMPY-04897 |
Thy1/CD90 Protein, Human, Recombinant
Thy-1 cell surface antigen,CD90 |
Human | HEK293 Cells |
Thy1/CD90 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is B0YJA4. | |||
TMPJ-00630 |
B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7,CD80,T-lymphocyte activation antigen CD80,Activa... |
Cynomolgus | HEK293 Cells |
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ... | |||
TMPY-03188 |
MD1 Protein, Human, Recombinant (hFc)
MMD-1,lymphocyte antigen 86,MD-1,... |
Human | HEK293 Cells |
MD1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is O95711. | |||
TMPJ-00641 |
B7-2 Protein, Rhesus macaque, Recombinant (His)
Activation B7-2 antigen,T-lymphocyte activation |
Rhesus | HEK293 Cells |
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8. | |||
TMPK-00737 |
EVA-1/MPZL2 Protein, Human, Recombinant (hFc)
Eva,Mpzl2,EVA-1,EVA 1,EVA1,Epithe... |
Human | HEK293 Cells |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons. EVA-1/MPZL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecu... | |||
TMPK-00738 |
EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc)
EVA 1,Mpzl2,Epithelial V-like antigen ... |
Mouse | HEK293 Cells |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epithelium and result in loss of structural integrity of the organ of Corti and progressive degeneration of hair cells, supporting cells, and spiral ganglion neurons. EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecu... | |||
TMPY-00968 |
CD157 Protein, Human, Recombinant (His)
bone marrow stromal cell antigen 1,CD1... |
Human | HEK293 Cells |
CD157 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is Q10588-1. | |||
TMPY-03999 |
MD2/LY96 Protein, Mouse, Recombinant (hFc)
lymphocyte antigen 96,ESOP-1,MD2,MD-2 |
Mouse | HEK293 Cells |
LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activa... | |||
TMPH-01593 |
CT83 Protein, Human, Recombinant (E. coli, His)
CXorf61,Kita-kyushu lung cancer antigen |
Human | E. coli |
CT83 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-01652 |
MLANA Protein, Human, Recombinant (B2M & His)
Antigen LB39-AA,Protein Melan-A,MLANA,Melanoma ... |
Human | E. coli |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MLANA Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 27.2 kDa and the accession number is Q16655. | |||
TMPJ-01436 |
MKI67 Protein, Human, Recombinant (GST)
Ki-67,Antigen Ki67,MKI67,KIA,antigen KI-67... |
Human | E. coli |
MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition... | |||
TMPH-01034 |
CTAG1A Protein, Human, Recombinant (hFc & Myc)
CTAG1,ESO1,LAGE-2,CT6.1,LAGE2,L <... |
Human | HEK293 Cells |
CTAG1A Protein, Human, Recombinant (hFc & Myc) is expressed in HEK293 mammalian cells with C-hFc-Myc tag. The predicted molecular weight is 48.1 kDa and the accession number is P78358. | |||
TMPH-01594 |
CT83 Protein-VLP, Human, Recombinant (His)
CXorf61,KK-LC-1,Cancer/testis antigen<... |
Human | HEK293 Cells |
CT83 Protein-VLP, Human, Recombinant (His) is expressed in HEK293. | |||
TMPH-01653 |
MLANA Protein, Human, Recombinant (His)
Protein Melan-A,Melanoma antigen recognized by T-ce... |
Human | P. pastoris (Yeast) |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MLANA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 15.2 kDa and the accession number is Q16655. | |||
TMPH-01619 |
LY6E Protein, Human, Recombinant (His & SUMO)
LY6E,Thymic shared antigen 1,Stem cell |
Human | E. coli |
LY6E Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is Q16553. | |||
TMPH-01033 |
CTAG1A Protein, Human, Recombinant (His)
CT6.1,LAGE2,CTAG,CTAG1,L antigen ... |
Human | E. coli |
CTAG1A Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 21.6 kDa and the accession number is P78358. | |||
TMPK-00301 |
CD5 Protein, Human, Recombinant (hFc & Avi)
CD5 molecule,CD5,LEU1,CD5 antigen,T1 |
Human | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127. | |||
TMPK-00642 |
CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
LEU1,T1,CD5,CD5 antigen,CD5 molec... |
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9. | |||
TMPY-00224 |
JAML Protein, Mouse, Recombinant (hFc)
AMICA,Gm638,adhesion molecule, interacts with CXADR anti... |
Mouse | HEK293 Cells |
JAML Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.5 kDa and the accession number is Q80UL9. | |||
TMPK-00643 |
CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
T1,LEU1,CD5,CD5 antigen,CD5 molec... |
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9. | |||
TMPK-00300 |
CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
T1,CD5,LEU1,CD5 antigen,CD5 molec... |
Mouse | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.9 kDa and the accession number is P13379. | |||
TMPK-00302 |
CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated
T1,LEU1,CD5 molecule,CD5 antigen,... |
Human | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127. | |||
TMPJ-00342 |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
Lymphocyte activation antigen CD30,TNFRSF8,Tumor ne... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-95 KDa and the accession number is P28908. | |||
TMPY-01733 |
SIGNR1 Protein, Mouse, Recombinant (His)
CD209b antigen,DC-SIGNR1,OtB7,SIGNR1 |
Mouse | HEK293 Cells |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPY-04093 |
JAML Protein, Mouse, Recombinant (His)
Gm638,AMICA,adhesion molecule, interacts with CXADR anti... |
Mouse | HEK293 Cells |
JAML Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q80UL9. | |||
TMPJ-00341 |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
TNFRSF8,Ki-1 antigen,CD30,CD30L receptor,T... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908. | |||
TMPJ-00340 |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
Lymphocyte activation antigen CD30,TNFRSF8,CD30,Ki-... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is P28908. | |||
TMPK-00632 |
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP... |
Cynomolgus | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. | |||
TMPK-00516 |
BST1 Protein, Cynomolgus, Recombinant (His)
Bp-3,CD157,Bst1,BST-1,Ly65,Bp3, |
Cynomolgus | HEK293 Cells |
BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism. | |||
TMPH-02769 |
LY6G Protein, Mouse, Recombinant (His)
Ly-6G.1,Lymphocyte antigen 6G,Ly6g |
Mouse | P. pastoris (Yeast) |
N/A. LY6G Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 11.9 kDa and the accession number is P35461. | |||
TMPJ-00184 |
CD20 Protein, Human, Recombinant (Flag)
B-lymphocyte surface antigen B1,B-lymphocy... |
Human | HEK293 Cells |
CD20 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 33-37 kDa and the accession number is P11836. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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T38356 |
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
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1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation... |