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Anti-CD86 Monoclonal Antibody-AF647

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产品编号 TMAZ-0050A6
别名 T-lymphocyte activation antigen CD86, FUN-1, CTLA-4 counter-receptor B7.2, BU63, B70, Activation B7-2 antigen

Anti-CD86 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody-AF647 can be used in ELISA, FACS.

Anti-CD86 Monoclonal Antibody-AF647

Anti-CD86 Monoclonal Antibody-AF647

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产品编号 TMAZ-0050A6 别名 T-lymphocyte activation antigen CD86, FUN-1, CTLA-4 counter-receptor B7.2, BU63, B70, Activation B7-2 antigen

Anti-CD86 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody-AF647 can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 1,9797日内发货
50 μg¥ 3,2987日内发货
100 μg¥ 4,9477日内发货
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产品介绍

生物活性
产品描述
Anti-CD86 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
别名T-lymphocyte activation antigen CD86, FUN-1, CTLA-4 counter-receptor B7.2, BU63, B70, Activation B7-2 antigen
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of CD86 overexpressed 293F cells with TMAZ-0050A6BI, which was counjucated with SA-PE (red). The WT 293F control is black line.
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CD86 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4 (PubMed: 12196291). May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed: 7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity)|Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation|(Microbial infection) Acts as a receptor for adenovirus subgroup B
偶联与修饰
偶联
AF647
其他可选修饰符
Biotin/APC/PE/AF488/AF555
可提供抗体种类
2
抗原信息
免疫原
CD86
抗原种属
Human
基因ID
942
Uniprot ID
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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