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Anti-FAS Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting FAS. Anti-FAS Monoclonal Antibody-AF555 can be used in ELISA, FACS.
Anti-FAS Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting FAS. Anti-FAS Monoclonal Antibody-AF555 can be used in ELISA, FACS.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 2,087.42¥ 3,599 | 7日内发货 | |
50 μg | ¥ 3,478.84¥ 5,998 | 7日内发货 | |
100 μg | ¥ 5,218.26¥ 8,997 | 7日内发货 |
产品描述 | Anti-FAS Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting FAS. Anti-FAS Monoclonal Antibody-AF555 can be used in ELISA, FACS. |
别名 | Apo-1 antigen, FASLG receptor, Apoptosis-mediating surface antigen FAS, Tumor necrosis factor receptor superfamily member 6 |
Ig Type | Rabbit monoclonal IgG |
交叉反应 | Human |
验证活性 | Flow cytometry analysis of FAS overexpressed 399F cells with TMAZ-0013A5, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
应用 | ELISA, FACS |
推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Single-pass type I membrane |
构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of FAS protein. |
纯化方式 | Protein A Affinity Purified |
性状 | Liquid |
缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
纯度 | > 95% as determined by SDS-PAGE. |
研究背景 | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) |
偶联 | AF555 |
其他可选修饰符 | Biotin/APC/PE/AF488/AF647 |
可提供抗体种类 | 1 |
免疫原 | FAS |
抗原种属 | Human |
基因ID | 355 |
Uniprot ID | |
研究领域 | Immunology Research |
分子量 | 150 kDa |
储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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