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Anti-MUC1 Monoclonal Antibody-AF647

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产品编号 TMAZ-0113A6
别名 Tumor-associated mucin, Tumor-associated epithelial membrane antigen, Polymorphic epithelial mucin, PEMT, Peanut-reactive urinary mucin, Mucin-1, Krebs von den Lungen-6, H23AG, Episialin, Carcinoma-associated mucin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3

Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.

Anti-MUC1 Monoclonal Antibody-AF647

Anti-MUC1 Monoclonal Antibody-AF647

Rating icon 还可以
产品编号 TMAZ-0113A6 别名 Tumor-associated mucin, Tumor-associated epithelial membrane antigen, Polymorphic epithelial mucin, PEMT, Peanut-reactive urinary mucin, Mucin-1, Krebs von den Lungen-6, H23AG, Episialin, Carcinoma-associated mucin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3

Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 3,5997日内发货
50 μg¥ 5,9987日内发货
100 μg¥ 8,9977日内发货
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产品介绍

生物活性
产品描述
Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
别名Tumor-associated mucin, Tumor-associated epithelial membrane antigen, Polymorphic epithelial mucin, PEMT, Peanut-reactive urinary mucin, Mucin-1, Krebs von den Lungen-6, H23AG, Episialin, Carcinoma-associated mucin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of MUC1 overexpressed 395F cells with TMAZ-0113A6, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MUC1 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity
偶联与修饰
偶联
AF647
其他可选修饰符
Biotin/APC/PE/AF488/AF555
可提供抗体种类
1
抗原信息
免疫原
MUC1
抗原种属
Human
基因ID
4582
Uniprot ID
研究领域
Cancer Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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