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Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 2,087.42¥ 3,599 | 7日内发货 | |
50 μg | ¥ 3,478.84¥ 5,998 | 7日内发货 | |
100 μg | ¥ 5,218.26¥ 8,997 | 7日内发货 |
产品描述 | Anti-MUC1 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF647 can be used in ELISA, FACS. |
别名 | PEMT, Krebs von den Lungen-6, Cancer antigen 15-3, Tumor-associated epithelial membrane antigen, Peanut-reactive urinary mucin, Episialin, Carcinoma-associated mucin, Breast carcinoma-associated antigen DF3, Tumor-associated mucin, H23AG, Polymorphic epithelial mucin, Mucin-1 |
Ig Type | Rabbit monoclonal IgG |
交叉反应 | Human |
验证活性 | Flow cytometry analysis of MUC1 overexpressed 395F cells with TMAZ-0113A6, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
应用 | ELISA, FACS |
推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Secreted |
构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MUC1 protein. |
纯化方式 | Protein A Affinity Purified |
性状 | Liquid |
缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
纯度 | > 95% as determined by SDS-PAGE. |
研究背景 | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity |
偶联 | AF647 |
其他可选修饰符 | Biotin/APC/PE/AF488/AF555 |
可提供抗体种类 | 1 |
免疫原 | MUC1 |
抗原种属 | Human |
基因ID | 4582 |
Uniprot ID | |
研究领域 | Cancer Research |
分子量 | 150 kDa |
储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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