abt-627 hydrochloride

Atrasentan hydrochloride (ABT-627 hydrochloride) 是内皮素 A 受体选择性拮抗剂，抑制内皮素 A 受体活性的IC50为 0.0551 nM。

ABT-418 hydrochloride is a selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. It activates cholinergic channel and can be used for the research of Alzheimer's disease.

Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.

ABT-702 hydrochloride，一种有效的腺苷激酶 (AK) 抑制剂，其IC50值为1.7 nM。

ABT-639 hydrochloride 是选择性的、新型的 T 型 Ca2+通道阻滞剂。

ABT-491 hydrochloride is an active platelet activator receptor (PAF-R) antagonist with good selectivity and oral administration.