MMP13-IN-3

MMP13-IN-3 是口服有效的MMP-13选择性抑制剂，IC50为 1 nM，比其他 MMP 的选择性高 1000倍多。MMP13-IN-3在用于骨关节炎方面有研究的价值。

Neurotensin(8-13) 3TFA(60482-95-3(free base)) 是神经降压素 (NT) 片段，神经降压素 (8-13) 导致细胞表面 NT1 受体 (NTR1) 密度降低。

Lixisenatide acetate 是一种胰高血糖素样肽 1 受体的激动剂，可用于研究 2 型糖尿病。

MMP-7-IN-3为一种高效MMP-7选择性抑制剂，能够在单侧输尿管梗阻的小鼠模型中阻止肾纤维化的发展。

(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate，产品编号为T66648，CAS号为868540-15-2，是一种在生命科学研究领域有用的有机化合物。

MMP-9-IN-3 是一种 MMP-9 抑制剂 (IC50: 5.56 nM)，可与 MMP-9 形成氢键。MMP-9-IN-3 对 AKT 的活性具有抑制作用 (IC50: 2.11 nM)。MMP-9-IN-3 具有细胞毒性，能够诱导细胞凋亡。MMP-9-IN-3 能够用于研究癌症。

MMP-3 Inhibitor 是一种多肽基质金属蛋白酶-3（MMP-3）抑制剂，Ki 值为 95 nM。MMP-3 inhibitor 具有抗癌抗肿瘤活性。

Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg mL against the M. tuberculosis strain H37Rv.

1,2-Di-13(Z)-docosenoyl-3-oleoyl-rac-glycerol is a triacylglycerol composed of 13(Z)-docosenoic acid at both the sn-1 and sn-2 positions and oleic acid at the sn-3 position.

MMP-13-IN-1是一种高效选择性的MMP-13抑制剂，IC50值为16 nM，可用于动脉粥样硬化研究。

Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester) 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6498，CAS号为 1309929-72-3。

MMP-13Substrate 是MMP-13的底物。MMP-13Substrate 可用于骨关节炎 (OA) 的研究。

MMP-3 Inhibitor acetate 是一种细胞渗透性强的人 MMP-3 抑制剂.

MMP-9 MMP-13 Inhibitor I 是 MMP-9 和 MMP-13 双重抑制剂，IC50 均为 0.9 nM。MMP-9 MMP-13 Inhibitor I 对 MMP-9 MMP-13 的选择性是其他 MMP 的 20 倍以上。

Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.

3-O-Acetyl-13-deoxyphomenone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125458，CAS号为 194241-10-6。

13(18)-Oleanen-3-ol是一种天然产物，属于葫芦科南瓜属，其产品编号为 TN1188，CAS号为 508-04-3。13(18)-Oleanen-3-ol可用作对照参考。

1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC is a phospholipid featuring palmitic acid at the sn-1 position and 13(S)-HpODE at the sn-2 position.

MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over MMP-1, 3, 7, 8, 9, 14, and TACE. Moreover, MMP13-IN-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. Consequently, MMP13-IN-2 holds great potential for advancing research on collagenase-related diseases.