L-Glutathione reduced

L-Glutathione reduced (Glutathione) 属于天然三肽，存在与细胞中，是一种内源性抗氧化剂，可以清除氧自由基。L-Glutathione reduced 是某些酶的辅助因子，参与蛋白质二硫键重排并减少过氧化物。

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.