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5-Fluorouridine 5'-O-β-D-galactopyranoside

Name: 5-Fluorouridine 5'-O-β-D-galactopyranoside
Brand: TargetMol
SKU: T38987
Price: 1430 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T38987Cas号 149965-92-4

别名 5'-O-β-D-galactosyl-5-fluorouridine, 5-Fluorouridine 5'-O-β-D-galactopyranoside

5-Fluorouridine 5'-O-β-D-galactopyranoside, also known as 5'-O-β-D-galactosyl-5-fluorouridine, is a prodrug of 5-Fluorouridine. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, which is a highly effective antineoplastic agent.

5-Fluorouridine 5'-O-β-D-galactopyranoside

还可以

产品编号 T38987 别名 5'-O-β-D-galactosyl-5-fluorouridine, 5-Fluorouridine 5'-O-β-D-galactopyranosideCas号 149965-92-4

规格	价格	库存	数量
100 mg	询价	期货
500 mg	询价	期货

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产品操作手册

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

产品介绍

生物活性

产品描述	5-Fluorouridine 5'-O-β-D-galactopyranoside, also known as 5'-O-β-D-galactosyl-5-fluorouridine, is a prodrug of 5-Fluorouridine. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, which is a highly effective antineoplastic agent.
体外活性	The ratio of the IC 50 of 5-Fluorouridine 5'-O-β-D-galactopyranoside (5'-O-β-D-galactosyl-5-fluorouridine) to that of 5-Fluorouridine determined on a variety of tumor cell lines in vitro ranged from 500:1-1000:1[1].
体内活性	5-Fluorouridine 5'-O-β-D-galactopyranoside (5'-O-β-D-galactosyl-5-fluorouridine) is more than 100x less toxic than 5-Fluorouridine to bone marrow cells in Balb/c mice[1].
别名	5'-O-β-D-galactosyl-5-fluorouridine, 5-Fluorouridine 5'-O-β-D-galactopyranoside

化学信息

分子量	424.334
分子式	C₁₅H₂₁FN₂O₁₁
CAS No.	149965-92-4

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments

一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent

DMSO+ 30%PEG300+ 5%Tween 80 + 60% ddH2O. 那么您的工作液浓度为 2 mg/mL 。

母液配置方法: 2 mg 药物溶于 50 μLDMSO TargetMol | reagent

（母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法: 取 50μLDMSO TargetMol | reagent

母液，添加 300 μLPEG300 TargetMol | reagent

混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLddH2O TargetMol | reagent

混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

5-Fluorouridine 5'-O-b-D-galactopyranoside5'-O-b-D-galactosyl-5-fluorouridine5-Fluorouridine 5'-O-beta-D-galactopyranoside5'-O-beta-D-galactosyl-5-fluorouridine5Fluorouridine 5'OβDgalactopyranoside5 Fluorouridine 5' O β D galactopyranoside

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