|
TMPY-03660
|
p67phox Protein, Human, Recombinant
NCF-2,NOXA2,P67-PHOX,P67PHOX,neutrophil cytosolic f...
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Human
|
Baculovirus Insect Cells
|
|
p67phox Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 30 kDa and the accession number is AAH01606.1. |
|
TMPY-03619
|
p67phox Protein, Human, Recombinant (His & GST)
P67-PHOX,P67PHOX,neutrophil cytosolic factor 2,NCF-...
|
Human
|
Baculovirus Insect Cells
|
|
p67phox Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.6 kDa and the accession number is AAH01606.1. |
|
TMPH-01163
|
CXCL5 Protein, Human, Recombinant (His)
Epithelial-derived neutrophil-activating protein 78...
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Human
|
E. coli
|
|
CXCL5 Protein, Human, Recombinant (His) is expressed in E. coli. |
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TMPH-00794
|
Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)
napA,DNA protection during starvation protein,Bacterioferrit...
|
Helicobacter pylori
|
E. coli
|
|
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role... |
|
TMPJ-00848
|
NCF1 Protein, Human, Recombinant (His)
Nox-organizing protein 2/SH3 and PX domain-containing protei...
|
Human
|
E. coli
|
|
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and ... |
|
TMPJ-00082
|
NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)
Lipocalin-2,SV-40-induced 24P3 protein,Siderocalin LCN2,LCN2...
|
Mouse
|
HEK293 Cells
|
|
Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell sig... |
|
TMPH-00297
|
S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)
S100A9,BEE22,Protein S100-A9,S100 calcium-binding protein A9...
|
Bovine
|
E. coli
|
|
S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 34.5 kDa and the accession number is P28783. |
|
TMPH-01772
|
DEFA1 Protein, Human, Recombinant (GST)
MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,Neutrophil
|
Human
|
E. coli
|
|
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665. |
|
TMPH-02503
|
DEFA1 Protein, Mouse, Recombinant (GST & His)
HP-1,HNP-1,Defensin, alpha 1,DEFA1,DEFA2,MRS,Neutrophil<...
|
Mouse
|
E. coli
|
|
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477. |
|
TMPH-02997
|
Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)
Neutrophil-activating protein A,NAP A,HP-NAP,Bacter...
|
Mycobacterium smegmatis
|
E. coli
|
|
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. Dps Protein, Mycobacterium sme... |
|
TMPH-01773
|
ELANE Protein, Human, Recombinant (GST)
Neutrophil elastase,ELA2,Medullasin,Elastase-2,ELAN...
|
Human
|
E. coli
|
|
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. ELANE Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.6 kDa and the accession number is P08246. |
|
TMPJ-00541
|
CD177 Protein, Human, Recombinant (His)
PRV-1,HNA-2a,Human Neutrophil Alloantigen 2a,CD177,...
|
Human
|
HEK293 Cells
|
|
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phospha... |
|
TMPH-01070
|
CD177 Protein, Human, Recombinant (GST & His)
Human neutrophil alloantigen 2a,CD177,PRV1,Polycyth...
|
Human
|
E. coli
|
|
CD177 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 63.6 kDa and the accession number is Q8N6Q3. |
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TMPH-03751
|
CYBB Protein, Human, Recombinant (His)
NADPH oxidase 2,Heme-binding membrane glycoprotein gp91phox,...
|
Human
|
E. coli
|
|
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. |
|
TMPY-00672
|
Azurocidin/CAP37 Protein, Human, Recombinant (His)
AZU,NAZC,azurocidin 1,hHBP,AZAMP,HUMAZUR,CAP37,HBP,AZU1
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Human
|
HEK293 Cells
|
|
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n... |
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TMPY-01850
|
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ...
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Human
|
HEK293 Cells
|
|
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... |
|
TMPH-02755
|
LECT2 Protein, Mouse, Recombinant (His)
Chondromodulin II,Leukocyte cell-derived chemotaxin-2,Lect2
|
Mouse
|
E. coli
|
|
Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. LECT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.7 kDa and the accession number is O88803. |
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TMPH-03522
|
Alpha-hemolysin Protein, S. aureus, Recombinant (His)
Alpha-toxin,Alpha-HL
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. |
|
TMPY-01909
|
Elafin Protein, Human, Recombinant (His)
WAP3,ESI,peptidase inhibitor 3,SKALP,cementoin,MGC13613,WFDC...
|
Human
|
HEK293 Cells
|
|
Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific si... |
|
TMPY-02847
|
Moesin Protein, Human, Recombinant (aa 1-346, His)
moesin,HEL70
|
Human
|
E. coli
|
|
Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM proteins function as cross-linkers between plasma membranes and actin-based cytoskeletons. The sole Drosophila ERM protein, moesin, functions to promote cortical actin assembly and apical-basal polarity. As a result, cells lacking moesin lose epithelial characteristics and adopt invasi... |
|
TMPH-03523
|
Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)
Alpha-HL,Alpha-toxin
|
Staphylococcus aureus
|
E. coli
|
|
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. |
|
TMPK-00674
|
CD24 Protein, Cynomolgus, Recombinant (hFc)
FLJ22950,CD 24,MGC75043,FLJ43543,CD24A,CD24 molecule
|
Cynomolgus
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.2 kDa and the accession number is I7GKK1-1. |
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TMPK-00001
|
CD24 Protein-VLP, Human, Recombinant
CD24A,MGC75043,FLJ43543,CD 24,FLJ22950,CD24 molecule
|
Human
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 5.0 kDa and the accession number is P25063-1. |
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TMPK-00004
|
CD24 Protein, Human, Recombinant (GST)
CD 24,CD24 molecule,FLJ22950,FLJ43543,CD24A,MGC75043
|
Human
|
E. coli
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.6 kDa and the accession number is P25063. |
|
TMPJ-01060
|
CXCL6 Protein, Human, Recombinant (His)
SCYB6,Chemokine Alpha 3,CKA-3,GCP2,GCP-2,C-X-C Motif Chemoki...
|
Human
|
HEK293 Cells
|
|
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell... |
|
TMPK-01318
|
CD24 Protein-VLP, Cynomolgus, Recombinant
MGC75043,CD 24,FLJ43543,FLJ22950,CD24 molecule,CD24A
|
Cynomolgus
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 3.8 kDa and the accession number is XP_015304503.1. |
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TMPK-00006
|
CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated
CD 24,CD24A,FLJ43543,CD24 molecule,MGC75043,FLJ22950
|
Human
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.5 kDa and ... |
|
TMPK-00002
|
CD24 Protein, Human, Recombinant (His & Avi)
MGC75043,FLJ22950,CD 24,FLJ43543,CD24A,CD24 molecule
|
Human
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 6.5 kDa and the accession number is P25063... |
|
TMPJ-00833
|
MPO Protein, Mouse, Recombinant (His)
MPO,Myeloperoxidase
|
Mouse
|
HEK293 Cells
|
|
Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride, bromide, and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100, as well as the lipid and cholesterol components of LDL and HDL, promotes the development of a... |
|
TMPJ-00582
|
PRG3 Protein, Human, Recombinant (His)
Prepro-MBPH,Prepro-Major Basic Protein Homolog,Eosinophil Ma...
|
Human
|
HEK293 Cells
|
|
Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine an... |
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TMPH-01346
|
FPR1 Protein, Human, Recombinant (GST & His & Myc)
FPR1,N-formylpeptide chemoattractant receptor,N-formyl pepti...
|
Human
|
E. coli
|
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. FPR1 Protein, Human, Recombinant (GST & H... |
|
TMPJ-01394
|
CXCL15 Protein, Mouse, Recombinant (His)
Lungkine,C-X-C motif chemokine 15,Small-inducible cytokine B...
|
Mouse
|
HEK293 Cells
|
|
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. It plays an important role in lung-specific neutrophil trafficking during normal and inflammatory conditions. It also appears chemotactic for neutrophils. |
|
TMPK-00003
|
CD24 Protein, Human, Recombinant (His & Avi), Biotinylated
FLJ22950,CD24 molecule,MGC75043,CD 24,CD24A,FLJ43543
|
Human
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 6.5 kDa and the accession nu... |
|
TMPK-00005
|
CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
CD24A,FLJ22950,CD24 molecule,CD 24,FLJ43543,MGC75043
|
Human
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 29.9 kDa and ... |
|
TMPY-05252
|
Myeloperoxidase/MPO Protein, Human, Recombinant (His)
myeloperoxidase
|
Human
|
HEK293 Cells
|
|
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands. Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has ... |
|
TMPH-02658
|
FPR1 Protein, Mouse, Recombinant (GST & His & Myc)
Fpr1,N-formylpeptide chemoattractant receptor,N-formyl pepti...
|
Mouse
|
E. coli
|
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. FPR1 Protein, Mouse, Recombinant (GST & H... |
|
TMPK-00675
|
CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
MGC75043,FLJ43543,CD24 molecule,FLJ22950,CD 24,CD24A
|
Cynomolgus
|
HEK293 Cells
|
|
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.2 kDa... |
|
TMPH-02659
|
FPR2 Protein, Mouse, Recombinant (GST & His & Myc)
Fpr2,Formyl peptide receptor 2,Formylpeptide receptor-relate...
|
Mouse
|
E. coli
|
|
High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors. Stimulates chemotaxis in immune cells to site of infection or tissue damage upon recognition of several ligands, such as FMLP, or ligand involved in cell damage, disease or inflammation. Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. FPR2 Protein, Mouse,... |
|
TMPH-03577
|
Staphopain B Protein, S. aureus, Recombinant (GST)
Staphopain B,sspB,Staphylopain B,Staphylococcal cysteine pro...
|
Staphylococcus aureus
|
E. coli
|
|
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S.... |
|
TMPH-03578
|
SCIN Protein, S. aureus, Recombinant (His & Myc)
scn,Staphylococcal complement inhibitor
|
Staphylococcus aureus
|
E. coli
|
|
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ... |
|
TMPH-03296
|
Galectin-3/LGALS3 Protein, Rat, Recombinant (His)
Lgals3,IgE-binding protein,Carbohydrate-binding protein 35,L...
|
Rat
|
E. coli
|
|
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autop... |
|
TMPY-00517
|
LSP1 Protein, Human, Recombinant (His)
lymphocyte-specific protein 1,WP34,pp52
|
Human
|
HEK293 Cells
|
|
LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. LSP1 is a lymphocyte-specific intracellular Ca2(+)-binding protein. LSP1 localizes to nascent phagocytic cups during Fcgamma receptor-mediated phagocytosis, where it displays the same ... |
|
TMPJ-00760
|
CXCL7 Protein, Human, Recombinant
SCYB7,C-X-C Motif Chemokine 7,Leukocyte-Derived Growth Facto...
|
Human
|
E. coli
|
|
Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basi... |
|
TMPJ-00006
|
CXCL1 Protein, Mouse, Recombinant (His)
Scyb1,Growth-regulated α,Mgsa,Gro1,Growth-regulated alpha pr...
|
Mouse
|
HEK293 Cells
|
|
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63% identity to that of mouse MIP-2. KC is also approximately 60% identical ... |
|
TMPH-01213
|
DNASE1L3 Protein, Human, Recombinant (His)
DNase I homolog protein DHP2,DNAS1L3,DNase I-like 3,Deoxyrib...
|
Human
|
Baculovirus Insect Cells
|
|
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
|
TMPH-01214
|
DNASE1L3 Protein, Human, Recombinant
DHP2,Deoxyribonuclease I-like 3,Deoxyribonuclease gamma,DNas...
|
Human
|
E. coli
|
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Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
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TMPH-01212
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DNASE1L3 Protein, Human, Recombinant (His & Myc)
LSD,Liver and spleen DNase,Deoxyribonuclease I-like 3,DNAS1L...
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Human
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E. coli
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Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends. Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated mic... |
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TMPY-02908
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BPI Protein, Human, Recombinant (His)
BPIFD1,bactericidal/permeability-increasing protein,rBPI
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Human
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HEK293 Cells
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Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonuclear leukocytes. Bactericidal/permeability-increasing protein also is a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. Bactericidal/permeability-increasing protein contains two domains t... |
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TMPJ-00011
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CXCL2 Protein, Mouse, Recombinant
Gro-beta,GRO β,GROB,melanoma growth stimulatory activity bet...
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Mouse
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E. coli
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C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the hum... |
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TMPJ-00527
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SP-D Protein, Human, Recombinant (His)
Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,SP-D,Pulm...
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Human
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HEK293 Cells
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Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ... |
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