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Search Results for " endocrine "

Targets Recommended: Apoptosis Estrogen Receptor/ERR Others

61

抑制剂 & 化合物

7

天然产物

3

化合物库

15

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L2400	内分泌激素分子库		784 compounds
	784 种与内分泌系统相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L5500	毒性化合物库		262 compounds
	262 个细胞毒性化合物的特有集合，可用于高通量、高内涵筛选。
L3300	组胺&褪黑色素化合物库		153 compounds
	153 种生物活性小分子化合物，用于高通量、高内涵筛选；

化合物库

内分泌激素分子库

Cat.No: L2400

Compounds: 784

毒性化合物库

Cat.No: L5500

Compounds: 262

组胺&褪黑色素化合物库

Cat.No: L3300

Compounds: 153

Cat. No.	Product Name	Target	Signaling Pathways
T0695	Avobenzone 阿伏苯宗,Butyl methoxydibenzoylmethane,BF2AVB	Apoptosis; Estrogen Receptor/ERR; Others	Apoptosis; Endocrinology/Hormones; Others
	Avobenzone 是一种二苯甲酰甲烷内分泌干扰物，可直接与雌激素受体 β 结合，起到雌激素激动剂的作用。它是紫外线波段皮肤光防护防晒霜中应用最广泛的滤光剂之一。
T4504	Triclocarban Solubacter,Cutisan,Procutene,3,4,4′-Trichlorocarbanilide,三氯卡班	Antibacterial	Microbiology/Virology
	Triclocarban (Cutisan) 是一种抗菌剂，用于个人清洁产品。它有潜在干扰内分泌的作用，具有调节雄激素和雌激素活性以及其他激素介导的生物过程的能力。
T7839	Lasofoxifene Tartrate CP-336156,酒石酸拉索昔芬	Estrogen Receptor/ERR	Endocrinology/Hormones
	Lasofoxifene Tartrate (CP-336156) 是一种非甾体类的雌激素受体选择性调节剂 (SERM)。
T0787	Butylhydroxyanisole BHA,丁基羟基茴香醚,丁基大茴香醚,E320,Butylated hydroxyanisole	Antioxidant; Ferroptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Butylhydroxyanisole (BHA) 是一种抗氧化剂，能介导肝毒性、生殖器官发育和学习迟缓以及睡眠不足，用作食品防腐剂。它也是一种铁死亡诱导剂，能导致大脑和神经发育中断，具有神经毒性。
T34385	Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689	CaSR	GPCR/G Protein
	Ronacaleret HCl (SB-751689) 是一种小分子 CaSR 拮抗剂，可用于治疗内分泌与代谢疾病、皮肤和肌肉骨骼疾病。
T41244	Triticonazole	Antifungal	Microbiology/Virology
	Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。
TP1035L	Cyclic somatostatin Acetate Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)	Others	Others
	Cyclic somatostatin Acetate(38916-34-6(free base)) (Somatostatin-14) 是一种环状十四肽，可调节许多内分泌和神经系统功能。
T16090	MK-0773 PF-05314882	Androgen Receptor	Endocrinology/Hormones
	MK-0773 (PF-05314882) 是一种选择性雄激素受体调节剂，能与 AR 结合（IC50：6.6 nM），可用于研究内分泌异常引起的疾病。
T31611	Eldacimibe WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147	Acyltransferase	Metabolism
	Eldacimibe (WAY-ACA-147) 是一种ACAT2抑制剂，可用于治疗心血管疾病和内分泌与代谢疾病，研究动脉粥样硬化和高胆固醇血症。
TP1035	Cyclic somatostatin SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14	Others	Others
	Cyclic somatostatin (SRIF-14) 是生长激素释放抑制因子，可用于研究胃十二指肠溃疡出血。
T5627	Methoxychlor	Others	Others
	Methoxychlor 是一种有机氯农药，被认为是一种内分泌干扰物，会影响不同细胞模型中的 Ca²⁺ 稳态和细胞活力。
T13435	TR antagonist 1	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	TR antagonist 1 是一种高效甲状腺激素受体（TR）拮抗剂（对 TRα 和 TRβ 的 IC50 分别为 36 和 22 nM），可用于研究内分泌异常引起的疾病。
T5626	Atrazine Aktikon,Chromozin,Gesaprim,莠去津,Oleogesaprim,阿特拉津	Others	Others
	Atrazine (Oleogesaprim) 能够抑制光磷酸化，但通不会在短期内导致致命性或永久性细胞损伤，常用于控制一年生阔叶杂草。
T72049	4-N-Nonyloxyphenol 4-nonoxyphenol,p-Nonyloxyphenol	Others	Others
	4-N-Nonyloxyphenol (4-nonoxyphenol) 是一种基于高岭土纳米管的杂化光敏剂，是一种广泛使用的农药和内分泌干扰剂，可用于苯酚基农药的光降解。
T13898	SPD-473 citrate BTS 74398 citrate	Dopamine Receptor; 5-HT Receptor; Norepinephrine	GPCR/G Protein; Neuroscience
	SPD-473 citrate (BTS 74398 citrate) 是多巴胺重摄取抑制剂、去甲肾上腺素转运蛋白（NET）抑制剂和5-羟色胺重摄取抑制剂，可用于研究神经系统疾病和内分泌与代谢疾病。
T72042	Acetylsulfamerazine N-Acetylsulfamerazine	Others	Others
	Acetylsulfamerazine (N-Acetylsulfamerazine) 是磺胺甲基嗪的次级代谢产物，对纤维素消化和瘤胃内分泌的活性有轻微的抑制作用,具有抗微生物活性。
T68053	Denagliptin GW823093	DPP-4	Proteases/Proteasome
	Denagliptin是一种小分子二肽基肽酶IV（DPP-4）抑制剂，可用于治疗内分泌于代谢疾病，可用于研究2型糖尿病。
T77194L	D-Ribose 5-phosphate disodium dihydrate	Endogenous Metabolite	Metabolism
	D-Ribose 5-phosphate disodium dihydrate 参与磷酸戊糖途径，是磷酸戊糖途径的中间产物，可用于研究由核黄素缺乏引起的眼部疾病和内分泌与代谢疾病。
TP2026L	GRP (porcine) acetate GRP (porcine) acetate(74815-57-9 Free base)	Others	Others
	GRP (porcine) acetate 是从猪胰腺中提取的胃泌素释放肽。 GRP (porcine) acetate 可能在猪胰腺内分泌和外分泌的副交感神经调节中起作用。
T27245L	Eflucimibe L0081,F-12511	Acyltransferase	Metabolism
	Eflucimibe (L0081) 是一种酰基辅酶A：胆固醇酰基转移酶抑制剂，可用于治疗心血管疾病和内分泌与代谢疾病，可用于研究动脉粥样硬化和高脂血症。
TP2296L	TLQP 21 acetate	Complement System	Immunology/Inflammation
	TLQP 21 acetate 是 G 蛋白偶联受体补体 3a 受体 1 (C3aR1) 的有效激动剂。小鼠的 EC50 值为 10.3 μM，人的 EC50 值为 68.8 μM。它是一种 VGF 衍生肽，具有内分泌和内分泌特性。
T14226	Amino-PEG11-amine 氨基-十二聚乙二醇-氨基	Others; PROTAC Linker	Others; PROTAC
	Amino-PEG11-amine 是一种基于 PEG（12 个单位）的 PROTAC 接头，能够结合两种基于单乙基雌酚的配体，是制备用于乳腺癌内分泌治疗的更具选择性和活性的 ER 拮抗剂的替代策略。
T68043	Ciamexon Ciamexone,BM 41332,BM41332,BM-41332	Others	Others
	Ciamexon (Ciamexone) 是一种新型的免疫调节剂，在自身免疫性疾病的实验模型中具有良好的效果，几乎没有显示出细胞毒性。Ciamexon 可用于研究内分泌眼病和糖尿病，在短时间给药后眼科疾病得到轻微改善。
T61932	Nesuparib JPI-547/OCN-201	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	Nesuparib (JPI-547/OCN-201) 是一种有效的PARP抑制剂，对PARP 和TNKS1具有抑制作用。Nesuparib 具有抗肿瘤活性，可用于治疗肿瘤、内分泌与代谢疾病、泌尿生殖系统疾病，可用于研究神经性疼痛、神经退行性疾病和心血管疾病。
T0499	Oxybenzone 二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567	Apoptosis; Retinoid Receptor; Autophagy	Apoptosis; Autophagy; Metabolism
	Oxybenzone 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物，用作破坏内分泌的化学物质，可穿透胎盘和血脑屏障。它损害自噬，改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。
TP2236L	Cortistatin-8 acetate Cortistatin-8 acetate(485803-62-1 Free base)	GHSR	GPCR/G Protein
	Cortistatin-8 acetate 是一种皮质抑素类似物，是一种GHS-R拮抗剂，对生长激素促分泌素受体有抑制作用。Cortistatin-8 acetate 是一种合成皮质抑素衍生的生长素释放肽受体配体，不会改变人类对酰化生长素释放肽或海沙瑞林的内分泌反应。
T67791	BMS-903452	GPR	Endocrinology/Hormones; GPCR/G Protein
	BMS-903452是一种有效的、具有选择性的 GPR119激动剂，EC50为14 nM。BMS-903452可用于治疗急性和慢性啮齿动物糖尿病。GPR119主要在胰腺 b 细胞和胃肠道肠内分泌细胞中表达，对9种不同的细胞色素 P450酶没有显著的抑制作用(IC50 > 40 μM)，不激活 PXR (EC50>50 μM)，并且对肝脏(HEPG2)细胞系没有毒性。
T26553	Aclatonium Napadisilate Acaltonium napadisilate	Others	Others
	Aclatonium Napadisilate, a cholinergic agonist, has been shown to stimulates endocrine and exocrine pancreatic secretion.
T30837	Cgp 47645 Leflutrozole,Cgp-47645,Cgp47645	Others	Others
	CGP 47645 (Leflurozole) is an oral active non-steroidal aromatase inhibitor and antitumor agent with anti-tumor and endocrine effects.
T30834	Cgp 45688 Cgp45688,Cgp-45688	Others	Others
	CGP 45688 is an oral active non-steroidal aromatase inhibitor with anti-tumor and endocrine effects on rat breast tumors.
T20274	Dibenzyl phthalate AI300364,AI3-00364	Others	Others
	Dibenzyl phthalate is an endocrine-disrupting chemical. It also interferes with different cell signaling pathways involved in weight and glucose homeostasis.
T33607	NBI-34041 NBI34041,SB 723620,SB-723620,SB723620	Others	Others
	NBI-34041 is an effective and high-affinity CRF1 receptor antagonist that effectively reduces endocrine responses to CRF(1) receptor-mediated pharmacological and behavioral challenges.
T38272	Thiacloprid	AChR; Parasite	Microbiology/Virology; Neuroscience
	Thiacloprid 属于氯烟碱类杀虫剂，主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性，通过疏水或氢相互作用，结合到小沟槽中，改变 DNA 的结构和稳定性。
T39306	7-Oxodehydroabietic acid	Others	Others
	7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system.
T26200	Somatostatin RC 102 Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102	Others	Others
	Somatostatin RC 102 is a peptide hormone. It regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
T39244	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.
TP1306	GLP-1(7-37)
	GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.
TP1863	Glucagon (19-29), human
	Glucagon is a 29-amino-acid peptide hormone liberated in the alpha cells of the islets of Langerhans. Glucagon-producing alpha cells represent one of the earliest populations of detectable islet cells in the developing endocrine pancreas.
T38379	4-tert-Octylphenol diethoxylate	Others	Others
	4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X. A known environmental contaminant, 4-tert-octylphenol diethoxylate is reported to be an endocrine disruptor in animal and human research studies, producing weak estrogenic effects.
T14223	Amino-PEG10-amine	Others	Others
	Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1].
TP1232	Amylin, amide, rat Amylin (rat)
	Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in ac
TP1610	Secretin, canine
	Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
T80985	Thyrotropin Pretiron,TSH
	Thyrotropin (TSH)为促甲状腺激素，由垂体前叶的促甲状腺细胞分泌，主要功能是调节甲状腺的内分泌活动。
T76538	Pancreatic polypeptide
	Pancreatic polypeptide 是由胰腺内分泌的 PP 细胞所分泌的多肽，具有调节胰腺分泌功能、影响肝糖原储存及胃肠分泌的作用。
TP1732	Galanin (1-30), human
	Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM. Endogenous peptide with multiple endocrine, metabolic and behavioral effects. Has been shown to have an action on intestinal
T81919	Locustatachykinin II Lom-TK II
	Locustachykinin II (Lom-TK II)为具有同源性的昆虫神经肽，与脊椎动物的tachykinin肽家族相似。此化合物适用于研究昆虫的内分泌系统。
T38077	TLQP-21 TFA
	TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2]. TLQP-21 TFA is a peptide of 21 amino acids. At a dose of 3 μM TLQP-21 induces up to ~69% of th...
T82447	Ergtoxin-1 ErgTx1
	Ergtoxin-1为钾离子通道阻断剂，源于墨西哥毒蝎Centruroides noxius的毒液。该化合物具有阻断神经、心脏及内分泌细胞ERG-K+通道的功能。
T36469	Atrazine Mercapturate	Others	Others
	Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system. Atrazine mercapturate is readily measured in urine samples.
T78039	Acetyl-(D-Arg2)-GRF (1-29) amide (human)
	Acetyl-(D-Arg2)-GRF (1-29) amide (human) 是一种针对人体的生长激素释放因子(GRF)拮抗剂，其主要作用是抑制生长激素(GH)的释放，广泛应用于内分泌学领域的研究。

化合物

Cat.No: T0695

Synonym: 阿伏苯宗,Butyl methoxydibenzoylmethane,BF2AVB

Target: Apoptosis, Estrogen Receptor/ERR, Others

Cat.No: T4504

Synonym: Solubacter,Cutisan,Procutene,3,4,4′-Trichlorocarbanilide,三氯卡班

Target: Antibacterial

Lasofoxifene Tartrate

Cat.No: T7839

Synonym: CP-336156,酒石酸拉索昔芬

Target: Estrogen Receptor/ERR

Butylhydroxyanisole

Cat.No: T0787

Synonym: BHA,丁基羟基茴香醚,丁基大茴香醚,E320,Butylated hydroxyanisole

Target: Antioxidant, Ferroptosis, Reactive Oxygen Species

Ronacaleret HCl

Cat.No: T34385

Synonym: SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689

Target: CaSR

Cat.No: T41244

Target: Antifungal

Cyclic somatostatin Acetate

Cat.No: TP1035L

Synonym: Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)

Target: Others

Cat.No: T16090

Synonym: PF-05314882

Target: Androgen Receptor

Cat.No: T31611

Synonym: WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147

Target: Acyltransferase

Cyclic somatostatin

Cat.No: TP1035

Synonym: SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14

Target: Others

Cat.No: T5627

Target: Others

TR antagonist 1

Cat.No: T13435

Target: Thyroid hormone receptor(THR)

Cat.No: T5626

Synonym: Aktikon,Chromozin,Gesaprim,莠去津,Oleogesaprim,阿特拉津

Target: Others

4-N-Nonyloxyphenol

Cat.No: T72049

Synonym: 4-nonoxyphenol,p-Nonyloxyphenol

Target: Others

SPD-473 citrate

Cat.No: T13898

Synonym: BTS 74398 citrate

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

Acetylsulfamerazine

Cat.No: T72042

Synonym: N-Acetylsulfamerazine

Target: Others

Cat.No: T68053

Synonym: GW823093

Target: DPP-4

D-Ribose 5-phosphate disodium dihydrate

Cat.No: T77194L

Target: Endogenous Metabolite

GRP (porcine) acetate

Cat.No: TP2026L

Synonym: GRP (porcine) acetate(74815-57-9 Free base)

Target: Others

Cat.No: T27245L

Synonym: L0081,F-12511

Target: Acyltransferase

TLQP 21 acetate

Cat.No: TP2296L

Target: Complement System

Amino-PEG11-amine

Cat.No: T14226

Synonym: 氨基-十二聚乙二醇-氨基

Target: Others, PROTAC Linker

Cat.No: T68043

Synonym: Ciamexone,BM 41332,BM41332,BM-41332

Target: Others

Cat.No: T61932

Synonym: JPI-547/OCN-201

Target: PARP, Wnt/beta-catenin

Cat.No: T0499

Synonym: 二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567

Target: Apoptosis, Retinoid Receptor, Autophagy

Cortistatin-8 acetate

Cat.No: TP2236L

Synonym: Cortistatin-8 acetate(485803-62-1 Free base)

Target: GHSR

Cat.No: T67791

Target: GPR

Aclatonium Napadisilate

Cat.No: T26553

Synonym: Acaltonium napadisilate

Target: Others

Cat.No: T30837

Synonym: Leflutrozole,Cgp-47645,Cgp47645

Target: Others

Cat.No: T30834

Synonym: Cgp45688,Cgp-45688

Target: Others

Dibenzyl phthalate

Cat.No: T20274

Synonym: AI300364,AI3-00364

Target: Others

Cat.No: T33607

Synonym: NBI34041,SB 723620,SB-723620,SB723620

Target: Others

Cat.No: T38272

Target: AChR, Parasite

7-Oxodehydroabietic acid

Cat.No: T39306

Target: Others

Somatostatin RC 102

Cat.No: T26200

Synonym: Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102

Target: Others

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Cat.No: T39244

Cat.No: TP1306

Glucagon (19-29), human

Cat.No: TP1863

4-tert-Octylphenol diethoxylate

Cat.No: T38379

Target: Others

Amino-PEG10-amine

Cat.No: T14223

Target: Others

Amylin, amide, rat

Cat.No: TP1232

Synonym: Amylin (rat)

Secretin, canine

Cat.No: TP1610

Cat.No: T80985

Synonym: Pretiron,TSH

Pancreatic polypeptide

Cat.No: T76538

Galanin (1-30), human

Cat.No: TP1732

Locustatachykinin II

Cat.No: T81919

Synonym: Lom-TK II

Cat.No: T38077

Cat.No: T82447

Synonym: ErgTx1

Atrazine Mercapturate

Cat.No: T36469

Target: Others

Acetyl-(D-Arg2)-GRF (1-29) amide (human)

Cat.No: T78039

Cat. No.	Product Name	Target	Signaling Pathways
T5623	Bisphenol A	Others; Endogenous Metabolite	Metabolism; Others
	Bisphenol A 是酚类内源性代谢合成物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
T4797	DEHP Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯	Others; Endogenous Metabolite	Metabolism; Others
	DEHP (Bis(2-ethylhexyl) phthalate) 是内源性代谢产物的一种。
TN6982	Diethyl phthalate 邻苯二甲酸二乙酯,1,2-diethyl benzene-1,2-dicarboxylate	Apoptosis	Apoptosis
	Diethyl phthalate (1,2-diethyl benzene-1,2-dicarboxylate) 是一种内分泌干扰物，影响 PC12 细胞凋亡系统。Diethyl phthalate 广泛用于许多塑料和个人护理产品。
T64353	4-tert-Octylphenol	Endogenous Metabolite	Metabolism
	4-tert-Octylphenol 是一种干扰内分泌的化学物质及雌激素药物，能诱导子代小鼠脑神经元祖细胞的凋亡，并通过减少溴脱氧尿苷（BrdU）、有丝分裂标志物Ki67以及磷酸组蛋白H3（p-Histone-H3）的表达，导致神经元祖细胞的增殖减少。这种物质不仅会干扰小鼠的大脑发育，还会影响其行为。
T20273	Diamyl phthalate NSC 4720,NSC-4720,NSC4720
	Diamyl phthalate is an agent of endocrine disruptor.
TN1550	Danshenxinkun A 丹参新醌甲,丹参新醌A	Others	Others
	Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone may intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental ada
T31536	Ditridecyl phthalate DTDP,Phthalic acid, ditridecyl ester,Nuoplaz,BRN 2023076,Polycizer 962BPA
	Ditridecyl phthalate is a kind of phthalate ester. Phthalate esters are esters of phthalic acid and are mainly used as plasticizers to soften polyvinyl chloride. They can be found in many different kind if products, including glues, building materials, pe

天然产物

Cat.No: T5623

Target: Others, Endogenous Metabolite

Cat.No: T4797

Synonym: Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯

Target: Others, Endogenous Metabolite

Diethyl phthalate

Cat.No: TN6982

Synonym: 邻苯二甲酸二乙酯,1,2-diethyl benzene-1,2-dicarboxylate

Target: Apoptosis

4-tert-Octylphenol

Cat.No: T64353

Target: Endogenous Metabolite

Diamyl phthalate

Cat.No: T20273

Synonym: NSC 4720,NSC-4720,NSC4720

Danshenxinkun A

Cat.No: TN1550

Synonym: 丹参新醌甲,丹参新醌A

Target: Others

Ditridecyl phthalate

Cat.No: T31536

Synonym: DTDP,Phthalic acid, ditridecyl ester,Nuoplaz,BRN 2023076,Polycizer 962BPA

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01150	Beta Klotho Protein, Mouse, Recombinant (His) Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB,beta-klo...	Mouse	HEK293 Cells
	Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce...
TMPK-00050	Leptin Protein, Mouse, Recombinant (hFc) LEP,Obesity factor,Leptin,LEPD,Obese protein,OBS,OB	Mouse	HEK293 Cells
	Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenital leptin deficiency (CLD) due to mutations in the leptin gene.
TMPK-00083	IGF1/IGF-I Protein, Human, Recombinant (hFc) IGF1A,胰岛素样生长因子,IBP1,IGF-I,MGF	Human	HEK293 Cells
	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes.
TMPH-00304	SV2A Protein, Bovine, Recombinant (His & Myc) Synaptic vesicle glycoprotein 2A,p87,SV2A	Bovine	HEK293 Cells
	Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. SV2A Protein, Bovine, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.8 kDa and the accession number is Q29397.
TMPK-01078	Beta Klotho Protein, Human, Recombinant (His) beta-klotho,MGC142213,betaKlotho,BKL,β-klotho,KLB,klotho bet...	Human	HEK293 Cells
	Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 111.6 kDa and the acces...
TMPH-03400	SLC17A6 Protein, Rat, Recombinant (His) Slc17a6,Vesicular glutamate transporter 2,Solute carrier fam...	Rat	P. pastoris (Yeast)
	Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Involved in the regulation of retinal hyaloid vessel regression during postnatal development. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. SLC17A6 Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 11.1 kDa an...
TMPJ-01113	RCN2 Protein, Human, Recombinant (His) Reticulocalbin-2,ERC55,RCN2,E6BP	Human	HEK293 Cells
	Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 cou...
TMPJ-01061	Nucleobindin-2 Protein, Human, Recombinant NUCB2,NEFA,Gastric cancer antigen Zg4,Nesfatin-1,Prepronesfa...	Human	E. coli
	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may ...
TMPJ-00740	PTH Protein, Human, Recombinant PTH,Parathyrin,Parathyroid Hormone,Parathormone	Human	E. coli
	Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processi...
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His) PK1,EGVEGF,PRK1,prokineticin 1	Human	Baculovirus Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) i...
TMPJ-00947	RPS19 Protein, Human, Recombinant RPS19,40S Ribosomal Protein S19	Human	E. coli
	40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan...
TMPJ-01415	ANGPTL4 Protein, Mouse, Recombinant (hFc) Angptl4,HFARP,Fasting-induced adipose factor,Fiaf,Secreted p...	Mouse	HEK293 Cells
	Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity...
TMPJ-00741	PTH Protein, Human, Recombinant (His) Parathyroid hormone,Parathyrin,PTH,Parathormone	Human	HEK293 Cells
	Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormon...
TMPY-02091	GAD67 Protein, Human, Recombinant (His) SCP,CPSQ1,glutamate decarboxylase 1 (brain, 67kDa),GAD	Human	Baculovirus Insect Cells
	Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type ...
TMPY-02640	FAM3B Protein, Human, Recombinant (hFc) PANDER,ORF9,PRED44,C21orf11,C21orf76,42056,family with seque...	Human	HEK293 Cells
	Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and beta- cells of pancreatic islets, insulin-secreting beta-TC3 cells, and glucagon-secreting alpha-TC cells. FAM3B causes apoptosis of beta-cells as assessed by electron microscopy, annexin Ⅴ fluorescent staining, and flow-cytometric terminal deoxynucleotidyl transferase-mediated dU...

重组蛋白

Beta Klotho Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01150

Species: Mouse

Expression System: HEK293 Cells

Leptin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00050

Species: Mouse

Expression System: HEK293 Cells

IGF1/IGF-I Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00083

Species: Human

Expression System: HEK293 Cells

SV2A Protein, Bovine, Recombinant (His & Myc)

Cat.No: TMPH-00304

Species: Bovine

Expression System: HEK293 Cells

Beta Klotho Protein, Human, Recombinant (His)

Cat.No: TMPK-01078

Species: Human

Expression System: HEK293 Cells

SLC17A6 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03400

Species: Rat

Expression System: P. pastoris (Yeast)

RCN2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01113

Species: Human

Expression System: HEK293 Cells

Nucleobindin-2 Protein, Human, Recombinant

Cat.No: TMPJ-01061

Species: Human

Expression System: E. coli

PTH Protein, Human, Recombinant

Cat.No: TMPJ-00740

Species: Human

Expression System: E. coli

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

Cat.No: TMPY-02945

Species: Human

Expression System: Baculovirus Insect Cells

RPS19 Protein, Human, Recombinant

Cat.No: TMPJ-00947

Species: Human

Expression System: E. coli

ANGPTL4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01415

Species: Mouse

Expression System: HEK293 Cells

PTH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00741

Species: Human

Expression System: HEK293 Cells

GAD67 Protein, Human, Recombinant (His)

Cat.No: TMPY-02091

Species: Human

Expression System: Baculovirus Insect Cells

FAM3B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02640

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0507	Dipentyl phthalate-3,4,5,6-d4
	Dipentyl phthalate-3,4,5,6-d4 是 Dipentyl phthalate 的氘代化合物。Dipentyl phthalate 的 CAS 号为 131-18-0。
TMIJ-0509	Diethyl Phthalate-d4
	Diethyl Phthalate-d4 是 Diethyl Phthalate 的氘代化合物。Diethyl Phthalate 的 CAS 号为 84-66-2。Diethyl phthalate 是一种内分泌干扰物，影响 PC12 细胞凋亡系统。Diethyl phthalate 广泛用于许多塑料和个人护理产品。
TMIJ-0506	Bis(2-ethylhexyl) Phthalate-d4
	Bis(2-ethylhexyl) Phthalate-d4 是 Bis(2-ethylhexyl) Phthalate 的氘代化合物。Bis(2-ethylhexyl) Phthalate 的 CAS 号为 117-81-7。Bis(2-ethylhexyl) phthalate 是内源性代谢产物的一种。

同位素标记化合物

Dipentyl phthalate-3,4,5,6-d4

Cat.No: TMIJ-0507

Diethyl Phthalate-d4

Cat.No: TMIJ-0509

Bis(2-ethylhexyl) Phthalate-d4

Cat.No: TMIJ-0506

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