|
TMPH-03747
|
CCDC112 Protein, Human, Recombinant (His & Myc)
Mutated in bladder cancer protein 1,Coiled-coil dom...
|
Human
|
E. coli
|
|
CCDC112 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.0 kDa and the accession number is Q8NEF3. |
|
TMPY-05030
|
PCDH7 Protein, Human, Recombinant (His)
BHPCDH
|
Human
|
Baculovirus Insect Cells
|
|
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number... |
|
TMPH-02669
|
GJA1 Protein, Mouse, Recombinant (His & Myc)
Gap junction 43 kDa heart protein,Gja1,Gap junction alpha-1 ...
|
Mouse
|
Baculovirus Insect Cells
|
|
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibi... |
|
TMPY-04263
|
UBE2T Protein, Human, Recombinant (His)
FANCT,PIG50,ubiquitin-conjugating enzyme E2T,HSPC150
|
Human
|
E. coli
|
|
Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer. |
|
TMPY-02220
|
HRAS Protein, Human, Recombinant (His)
HAMSV,Harvey rat sarcoma viral oncogene homolog,C-H-RAS,C-HA...
|
Human
|
Baculovirus Insect Cells
|
|
HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Defects in HRAS are the cause of faciocutaneoskeletal syndrome (FCSS). FCSS is a rare condition characterized by prenatally increase... |
|
TMPY-06762
|
PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated
BHPCDH
|
Human
|
Baculovirus Insect Cells
|
|
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 95.... |
|
TMPK-01220
|
CD164 Protein, Mouse, Recombinant (hFc)
CD164,Endolyn,MGC-24v,sialomucin,MUC-24,MGC-24
|
Mouse
|
HEK293 Cells
|
|
CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients. Silencing of CD164 could inhibit the progression of tumors in vivo and in vitro, which may become an effective target in the treatment of bladder cancer. CD164 Protein, Mouse, Recombinant (hF... |
|
TMPK-00931
|
CD164 Protein, Human, Recombinant (hFc)
MGC-24v,MUC-24,sialomucin,Cd164,Endolyn,MGC-24
|
Human
|
HEK293 Cells
|
|
CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients. Silencing of CD164 could inhibit the progression of tumors in vivo and in vitro, which may become an effective target in the treatment of bladder cancer. CD164 Protein, Human, Recombinant (hF... |
|
TMPH-00721
|
YgiS Protein, E. coli, Recombinant (His & SUMO)
Probable deoxycholate-binding periplasmic protein YgiS,ygiS
|
E. coli
|
E. coli
|
|
Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum. |
|
TMPJ-01248
|
Cytoglobin/CYGB Protein, Human, Recombinant (His)
Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...
|
Human
|
E. coli
|
|
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell. |
|
TMPH-02126
|
SORBS2 Protein, Human, Recombinant (His)
Sorbin and SH3 domain-containing protein 2,Arg-binding prote...
|
Human
|
E. coli
|
|
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. SORBS2 Pro... |
|
TMPJ-01381
|
ANXA10 Protein, Human, Recombinant
Annexin-10,ANX14,Annexin-14,ANXA10,Annexin A10
|
Human
|
E. coli
|
|
Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is reported that ANXA10 may be a clinical relevant marker for predicting outcome in both early and advanced stages of bladder cancer. |
|
TMPY-00507
|
UNC5B Protein, Human, Recombinant (hFc)
unc-5 homolog B (C. elegans),UNC5H2,p53RDL1
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular ... |
|
TMPY-04133
|
UNC5B Protein, Human, Recombinant (His)
UNC5H2,p53RDL1,unc-5 homolog B (C. elegans)
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular ... |
|
TMPJ-00160
|
EMMPRIN/CD147 Protein, Human, Recombinant (His)
5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived Collagena...
|
Human
|
HEK293 Cells
|
|
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,... |
|
TMPY-04003
|
UNC5B Protein, Rat, Recombinant (hFc)
unc-5 homolog B (C. elegans)
|
Rat
|
HEK293 Cells
|
|
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis. UNC5B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular we... |
|
TMPK-00906
|
PSCA Protein, Mouse, Recombinant (hFc)
UNQ206,PSCA,PRO232
|
Mouse
|
HEK293 Cells
|
|
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Mouse, Recomb... |
|
TMPK-00728
|
PSCA Protein, Human, Recombinant (hFc)
UNQ206,PRO232,PSCA
|
Human
|
HEK293 Cells
|
|
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Human, Recomb... |
|
TMPJ-00657
|
UPK2 Protein, Human, Recombinant (His)
Uroplakin II,Uroplakin-2,UPK2,UP2,UPII
|
Human
|
HEK293 Cells
|
|
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the ... |
|
TMPY-00648
|
UNC5A Protein, Human, Recombinant (hFc)
UNC5H1,unc-5 homolog A (C. elegans)
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... |
|
TMPJ-00715
|
FGF-19 Protein, Human, Recombinant (His)
FGF-19,Fibroblast growth factor 19,FGF19
|
Human
|
E. coli
|
|
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ... |
|
TMPY-04899
|
OGN/Osteoglycin Protein, Human, Recombinant (His)
OIF,OG,osteoglycin,SLRR3A
|
Human
|
HEK293 Cells
|
|
OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epith... |
|
TMPY-00999
|
UNC5A Protein, Human, Recombinant (His)
unc-5 homolog A (C. elegans),UNC5H1
|
Human
|
HEK293 Cells
|
|
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,... |
|
TMPY-04171
|
MFAP3 Protein, Human, Recombinant (hFc)
microfibrillar-associated protein 3
|
Human
|
HEK293 Cells
|
|
MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homo... |
|
TMPY-04930
|
Notch 2 Protein, Human, Recombinant (His)
AGS2,HJCYS,hN2,notch 2
|
Human
|
Baculovirus Insect Cells
|
|
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. Hajdu Cheney Syndrome (HCS) is a rare disease associated with mutations of NOTCH2 that lead to the translation of a truncated, presumably stable, NOTCH2 protein. NOTCH2 is down-regulated in colon cancer, and reduced express... |
|
TMPY-02384
|
MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)
metastasis suppressor 1,MIMB,MIM,MIMA
|
Human
|
E. coli
|
|
MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor... |
|
TMPH-01248
|
ADAR Protein, Human, Recombinant (His & SUMO)
ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...
|
Human
|
E. coli
|
|
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri... |
沪公网安备 31010602006700号