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Search Results for " biosynthesis "
Targets Recommended: Antifungal

291

抑制剂 & 化合物

126

天然产物

5

化合物库

112

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L9820 β-内酰胺类化合物库

97 compounds
97 种β-内酰胺类化合物的集合,可以用于高通量和高内涵筛选;
L7000 活性脂质化合物库

385 compounds
385 种生物活性小分子化合物,用于高通量、高内涵筛选;
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

黄酮类天然产物库
Cat.No: L6120
Compounds: 514
β-内酰胺类化合物库
Cat.No: L9820
Compounds: 97
活性脂质化合物库
Cat.No: L7000
Compounds: 385
内质网应激化合物库
Cat.No: L9700
Compounds: 193
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T37071 Pyrimethanil

Antifungal Microbiology/Virology
Pyrimethanil 是苯胺嘧啶类广谱接触杀菌剂,用于控制多种作物上的Botrytis spp.。它抑制灰霉病菌中氨基酸的生物合成,可用于霉菌感染的水果、蔬菜和观赏植物真菌病害防治的相关研究。
T19859 Nicosulfuron

Milagro,Accent,Motivell,烟嘧磺隆

Others Others
Nicosulfuron (Milagro) 是一种磺酰脲类的选择性除草剂,常用作出苗后的除草剂,保护玉米作物免受杂草的侵害。它也能够降低乙酰乳酸合酶的活性。
T14362 AY 9944

Others Others
AY 9944 是特异性的胆固醇生物合成抑制剂。它抑制 7- 脱氢胆固醇 Δ7- 还原酶 (IC50:13 nM),导致胆固醇不足和 7DHC 积累。在高剂量下,它可在培养的胚胎中抑制固醇 Δ7-Δ8 异构酶,造成胆固醇 8-en-3β-ol 的积累。
T20237 Fenhexamid

Elevate,Teldor,环酰菌胺

Antifungal Microbiology/Virology
Fenhexamid (Elevate) 是一种甾醇生物合成抑制剂,对植物病原真菌具有抗真菌活性。 Fenhexamid 用于农业,并在水果和蔬菜中以可测量的量存在。
T33828 O-Succinylhomoserine

O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine

Others Others
O-Succinylhomoserine (O-Succinyl-L-homoserine) 是大肠杆菌合成胱硫醚的中间体。
T15507 Hycanthone

Etrenol(mesylate),Win 249-33,海恩酮

DNA/RNA Synthesis; Topoisomerase; Parasite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Hycanthone (Etrenol(mesylate)) 是 Lucanthone 的生物活性代谢产物,是一种抗血吸虫病药。它是一个噻吨酮类 DNA 嵌入剂,可抑制 RNA 合成以及 DNA 拓扑异构酶 I 和 II。它通过直接蛋白质结合来抑制核酸生物合成并抑制嘌呤内切核酸酶1,KD 为 10 nM。
T20691 Fenpropidin

苯锈啶,Ro12-3049,Ro-12-3049,Ro 12-3049

Antifungal Microbiology/Virology
Fenpropidin (Ro-12-3049) 是甾醇类生物合成的抑制剂,具有杀菌的活性。
T26296 Triparanol

曲帕拉醇,MER-29,NSC 65345,NSC-65345,NSC65345

Apoptosis; Hedgehog/Smoothened Apoptosis; GPCR/G Protein; Stem Cells
Triparanol (NSC-65345) 干扰 Hedgehog 信号分子的翻译后修饰以及其受体 PTCH1 的甾醇传感域,导致 Hedgehog 信号的下调。 Triparanol 抑制人类肿瘤生长,是一种具有高眼毒性的抗血脂剂。
T20625 Prochloraz

咪鲜胺,Sporgon,Prelude

Estrogen Receptor/ERR; AhR; Androgen Receptor; Antifungal Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology
Prochloraz (Prelude) 是咪唑类抗真菌剂。Prochloraz 抑制羊毛甾醇的细胞色素 P450 依赖性 14α-脱甲基作用,由此抑制麦角固醇的生物合成,从而导致真菌细胞膜破裂和细胞死亡。它也是雌激素受体和 雄激素受体的拮抗剂,IC50分别为25 μM 和4 μM, 并激活芳烃受体,EC50为1μM。
T2305 Isavuconazole

艾沙康唑,BAL-4815,RO-0094815

P450; Antibiotic; Antifungal Metabolism; Microbiology/Virology
Isavuconazole (RO-0094815) 是一种三唑类前药,对酵母、霉菌和二型真菌具有抗真菌活性。它抑制麦角固醇生物合成,导致真菌膜结构和功能的破坏。它是 CYP3A4抑制剂。
T6893 MK-886

MK886,L 663536

Apoptosis; Leukotriene Receptor; COX; PPAR; FLAP Apoptosis; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
MK-886 (L 663536)是一种细胞可渗透的,具有口服活性的 FLAP (IC50为 30 nM) 和白三烯生物合成 (完整白细胞和人全血中的IC50分别为 3 nM 和 1.1μM) 的抑制剂。它也是一种非竞争性PPARα拮抗剂,可以诱导细胞凋亡。
T19721 Epoxiconazole

BAS-480F,BAS 480F,EC 406 850 2,氟环唑,BAS480F,EC-406-850-2

Antifungal Microbiology/Virology
Epoxiconazole (BAS-480F) 是一种 14-α 去甲基化酶抑制剂,抑制麦角甾醇的合成和真菌细胞壁的形成。它是一种杀菌剂,对耐多菌灵和耐苯甲酰胺的菌株均表现出强大的抑制作用,可用于控制多种农作物病害。
T24327 L 674573

L 674,573,L674,573,L-674,573,L674573,L-674573

Leukotriene Receptor GPCR/G Protein
L 674573是白三烯生物合成的抑制剂。
T77625 CCG-13514

Others Others
CCG-13514 是一种待开发的生化试剂,可用于生物合成。
T24306 L 651896

L651896,L-651896

Leukotriene Receptor; Lipoxygenase GPCR/G Protein; Metabolism
L 651896 是一种新型白三烯生物合成和 5-脂氧合酶抑制剂,可用于研究呼吸系统疾病和心血管疾病。
T72045 Fmoc-N-methyl-L-alloisoleucine

Others Others
Fmoc-N-methyl-L-alloisoleucine是一种生化试剂,可用于生物合成。
TQ0115 NB-598

Antifungal Microbiology/Virology
NB-598 是一种鲨烯环氧化酶竞争性抑制剂,可以阻碍甘油三酯的生物合成。
T14564 BI-4924

Others Others
BI-4924 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM). It has excellent Microsomal and hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis at 72 h ( IC50: 2200 nM).
T12092 Monacolin J

Antibiotic MB 530A,Lovastatin diol lactone,辛伐他汀内酯二醇

HMG-CoA Reductase; Autophagy Autophagy; Metabolism
Monacolin J (Antibiotic MB 530A) 是一种胆固醇生物合成抑制剂,抑制 HMG-CoA 还原酶的活性。
T32237 Isoxaben

EL 107,NA 8318,Isoxaben; EL 107; NA 8318

Cell wall Immunology/Inflammation
Isoxaben (EL 107) 是一种细胞壁生物合成的特异性抑制剂,常作为除草剂使用,可抑制放射性标记的葡萄糖掺入酸不溶性细胞壁部分。
T27112 Cytembena

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Cytembena 是一种细胞抑制剂,是一种致癌化合物,可之间纤维腺瘤发生的几率。Cytembena 广泛地抑制 DNA 的生物合成。
T11933 MAC13772

Others Others
MAC13772 是一种 BioA 酶的有效抑制剂,IC50 为 250 nM,从而抑制生物素的生物合成。 MAC13772 具有抗菌活性。
T9994 WAY-620521

Others Others
WAY-620521是一种用于细胞的高通量测定小分子。
T9369L UDP-a-D-Galactose disodium salt

Others Others
UDP-a-D-Galactose disodium salt 是半乳糖基转移酶的供体底物,用于含半乳糖的寡糖的生物合成。
T0506 Clotrimazole

克霉唑,BAY b 5097,FB 5097

Antibacterial; Antibiotic; Antifection; Autophagy; Antifungal Autophagy; Microbiology/Virology
Clotrimazole (FB 5097) 是咪唑衍生物,有抗真菌和抗菌活性,是 P450抑制剂。
T31163 Cytidine 5'-diphosphate disodium

CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt

Others Others
Cytidine 5'-diphosphate disodium (CDP sodium salt) 产生 CTP 以支持 DNA 和 RNA 生物合成和核糖核苷酸还原酶以产生 dCMP。
T27026 CJ-13,610

CJ 13610,CJ-13610

Lipoxygenase Metabolism
CJ-13,610 是一种具有口服活性的非氧化还原型 5-脂氧合酶 (5-LOX) 抑制剂。 CJ-13,610 抑制白三烯 B4 的生物合成并调节巨噬细胞中 IL-6 mRNA 的表达。
T33584 Namirotene

CBS 211A,Cbs 211 A

Others Others
Namirotene (CBS 211A) 是一种蛋白质生物合成抑制剂,是一种人工合成的维甲酸类似物,可用于研究角膜疾病、角膜溃疡和干眼综合征。
T4982 Benznidazol

苄哒唑,苄硝唑,Radanil,Benznidazole,Ro 71051,Ro 07-1051

Antibiotic; Parasite Microbiology/Virology
Benznidazol (Benznidazole) 是一种抗寄生虫药物,对哥伦比亚 T. cruzi 菌株的 IC50值为 20.35 μM,有潜力研究美洲锥虫病。
T0002 Ethamsylate

Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Ethamsylate (Dicynene) 通常用作止血药,增加毛细血管内皮阻力和血小板粘附,抑制前列腺素的生物合成和作用。
T2199 Myclobutanil

Systhane,腈菌唑

Antifungal Microbiology/Virology
Myclobutanil (Systhane) 是康唑类抗真菌剂,可用作农药。
T19508 Peroxidase

Others Others
Peroxidase 来自辣根,在先天免疫、氧化活性氧、激素生物合成和多种疾病的发病机制等方面具有重要作用。
T30615 Bupicomide

Hydroxylase Metabolism
Bupicomide 是一种多巴胺β羟化酶抑制剂,具有抗高血压和血管扩张活性,可降低14C-多巴胺的14C-去甲肾上腺素生物合成,可用于研究高血压。
T65347 Methyl acetyl-L-cysteinate

(R)-Methyl 2-acetamido-3-mercaptopropanoate,N-Acetyl-L-cysteine methyl ester

Amino Acids and Derivatives Metabolism
Methyl acetyl-L-cysteinate (N-Acetyl-L-cysteine methyl ester) 是一种半胱氨酸衍生物,可用于生物合成且与机体代谢和免疫有关。
T8332 Bipenquinate

Dehydrogenase Metabolism
Bipenquinate 是一种有效的、选择性的二氢乳清酸脱氢酶 (DHODH) 抑制剂,IC50 为 20 nM,阻断嘧啶的从头生物合成。
T5955 Tricyclazole

三环唑,Tricyclazol

Antibacterial Microbiology/Virology
Tricyclazole (Tricyclazol) 是一种源自五肽的黑色素生物合成抑制剂,是一种独特的杀菌剂,用于防治水稻稻瘟病菌。
T6586 Mildronate dihydrate

Meldonium,米屈肼(二水合物),Mildronate

Others Others
Mildronate dihydrate 是心血管保护药,可竞争性的抑制BBOX1和OCTN2。它能够诱导长链脂肪酸代谢从线粒体向过氧化物酶体的重定向。Mildronate 能够作用于人重组 BBOX (IC50:34-62 μM),以及人OCTN2 (EC50:21 μM)。
T19781 Clomazone

Gamit,FMC 57020,Command,异恶草松,Dimethazone,Magister

Others Others
Clomazone (Magister) 是一种能够用于控制棉花,豌豆,南瓜,大豆,地瓜,烟草的一年生草和阔叶杂草的广谱抗菌剂。
T1998 CHS-828

CHS 828,GMX1778

Apoptosis; NAMPT Apoptosis; Metabolism
CHS-828 (GMX1778) 是一种竞争性的烟酰胺磷酸化转移酶抑制剂,IC50值 <25 nM。它通过降低细胞中的 NAD+水平发挥细胞毒性作用,具有抗癌活性。
T17176 Salicyl-AMS

Antibacterial Microbiology/Virology
Salicyl-AMS 是一种分支杆菌生长素生物合成抑制剂,能在体外缺铁的情况下抑制分枝杆菌的生长。
T32490 L-161240

L-161,240

Antibacterial Microbiology/Virology
L-161240 是一种与脂质A生物合成有关的抗菌剂,在DEACET测定IC50值为 30 nM,并且对野生型大肠杆菌的MIC值为1-3μg/ mL。
T4055 Etoxazole

Others Others
Etoxazole 是一种杀螨剂/杀虫剂,通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。
T15608 Jarin-1

Others Others
Jarin-1 是一种茉莉酸-酰胺基合成酶 (JAR1) 抑制剂,IC50 为 3.8 μM。Jarin-1 特异性抑制拟南芥和其他植物中具有生物活性的 JA-Ile 的生物合成。
T1447 Fenclonine

Fenchlonine,PCPA,CP-10188,芬克洛宁,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine

Hydroxylase Metabolism
Fenclonine (CP-10188) 是一种有效的色氨酸羟化酶(Trp)的不可逆抑制剂。其中色氨酸羟化酶是 5-羟色胺生物合成的限速酶。
T1869 PluriSIn 1

4-吡啶羧酸 2-苯基酰肼,NSC 14613,PluriSIn #1,PluriSln 1

Apoptosis; Dehydrogenase; Stearoyl-CoA Desaturase (SCD) Apoptosis; Metabolism
PluriSIn 1 (NSC 14613) 是一种酰基-辅酶 A 去饱和酶抑制剂,是一种多能细胞特异性的抑制剂。
T0260 Meclofenamic acid sodium

Meclofenamate Sodium,Movens,Meclomen,甲氯灭酸钠,Meclonax

Gap Junction Protein; COX Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience
Meclofenamic acid sodium (Movens) 是一种非甾体抗炎药,可用于治疗关节炎 、缓解疼痛、痛经和严重月经失血。它是一种非选择性的缝隙连接阻断剂,是一种高选择性的脂肪和肥胖相关酶抑制剂。
T35973 Cholesterol-5α,6α-epoxide

Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176

Others Others
Cholesterol-5α,6α-epoxide (Epoxycholesterol) 是胆固醇氧化产生的代谢产物。 在应用他莫昔芬和 PBPE 后,5α,6α-环氧胆甾烷醇通过与 LXRβ 结合诱导三酰甘油生物合成。
T21482 Uniconazole

P450; ROS Kinase Metabolism; Tyrosine Kinase/Adaptors
Uniconazole 是植物生长调节剂,能够抑制细胞色素 P450 707As (Ki=68 nM)。他是分解脱落酸的酶家族成员,能够抑制赤霉素和甾醇的生物合成。
T3268 Mildronate

Kvaterin,米屈肼,Meldonium,Quaterin

Hydroxylase Metabolism
Mildronate (Meldonium) 是心血管保护药,能够竞争性的抑制 BBOX1和 OCTN2。作用于人重组 BBOX 的(IC50:34-62 μM)、人 OCTN2 (EC50:21 μM)。它能够诱导长链脂肪酸代谢从线粒体向过氧化物酶体的重定向。
T22352 L-Gulose

Others; Endogenous Metabolite Metabolism; Others
L-Gulose 是一种合成维生素 C 的生物中间体,是一种 L-sorbosone 的呋喃糖形式,是L 己糖。

化合物

Pyrimethanil
Cat.No: T37071
Synonym:
Target: Antifungal
Nicosulfuron
Cat.No: T19859
Synonym: Milagro,Accent,Motivell,烟嘧磺隆
Target: Others
AY 9944
Cat.No: T14362
Synonym:
Target: Others
Fenhexamid
Cat.No: T20237
Synonym: Elevate,Teldor,环酰菌胺
Target: Antifungal
O-Succinylhomoserine
Cat.No: T33828
Synonym: O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine
Target: Others
Hycanthone
Cat.No: T15507
Synonym: Etrenol(mesylate),Win 249-33,海恩酮
Target: DNA/RNA Synthesis, Topoisomerase, Parasite
Fenpropidin
Cat.No: T20691
Synonym: 苯锈啶,Ro12-3049,Ro-12-3049,Ro 12-3049
Target: Antifungal
Triparanol
Cat.No: T26296
Synonym: 曲帕拉醇,MER-29,NSC 65345,NSC-65345,NSC65345
Target: Apoptosis, Hedgehog/Smoothened
Prochloraz
Cat.No: T20625
Synonym: 咪鲜胺,Sporgon,Prelude
Target: Estrogen Receptor/ERR, AhR, Androgen Receptor, Antifungal
Isavuconazole
Cat.No: T2305
Synonym: 艾沙康唑,BAL-4815,RO-0094815
Target: P450, Antibiotic, Antifungal
MK-886
Cat.No: T6893
Synonym: MK886,L 663536
Target: Apoptosis, Leukotriene Receptor, COX, PPAR, FLAP
Epoxiconazole
Cat.No: T19721
Synonym: BAS-480F,BAS 480F,EC 406 850 2,氟环唑,BAS480F,EC-406-850-2
Target: Antifungal
L 674573
Cat.No: T24327
Synonym: L 674,573,L674,573,L-674,573,L674573,L-674573
Target: Leukotriene Receptor
CCG-13514
Cat.No: T77625
Synonym:
Target: Others
L 651896
Cat.No: T24306
Synonym: L651896,L-651896
Target: Leukotriene Receptor, Lipoxygenase
Fmoc-N-methyl-L-alloisoleucine
Cat.No: T72045
Synonym:
Target: Others
NB-598
Cat.No: TQ0115
Synonym:
Target: Antifungal
BI-4924
Cat.No: T14564
Synonym:
Target: Others
Monacolin J
Cat.No: T12092
Synonym: Antibiotic MB 530A,Lovastatin diol lactone,辛伐他汀内酯二醇
Target: HMG-CoA Reductase, Autophagy
Isoxaben
Cat.No: T32237
Synonym: EL 107,NA 8318,Isoxaben; EL 107; NA 8318
Target: Cell wall
Cytembena
Cat.No: T27112
Synonym:
Target: DNA/RNA Synthesis
MAC13772
Cat.No: T11933
Synonym:
Target: Others
WAY-620521
Cat.No: T9994
Synonym:
Target: Others
UDP-a-D-Galactose disodium salt
Cat.No: T9369L
Synonym:
Target: Others
Clotrimazole
Cat.No: T0506
Synonym: 克霉唑,BAY b 5097,FB 5097
Target: Antibacterial, Antibiotic, Antifection, Autophagy, Antifungal
Cytidine 5'-diphosphate disodium
Cat.No: T31163
Synonym: CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt
Target: Others
CJ-13,610
Cat.No: T27026
Synonym: CJ 13610,CJ-13610
Target: Lipoxygenase
Namirotene
Cat.No: T33584
Synonym: CBS 211A,Cbs 211 A
Target: Others
Benznidazol
Cat.No: T4982
Synonym: 苄哒唑,苄硝唑,Radanil,Benznidazole,Ro 71051,Ro 07-1051
Target: Antibiotic, Parasite
Ethamsylate
Cat.No: T0002
Synonym: Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin
Target: Prostaglandin Receptor
Myclobutanil
Cat.No: T2199
Synonym: Systhane,腈菌唑
Target: Antifungal
Peroxidase
Cat.No: T19508
Synonym:
Target: Others
Bupicomide
Cat.No: T30615
Synonym:
Target: Hydroxylase
Methyl acetyl-L-cysteinate
Cat.No: T65347
Synonym: (R)-Methyl 2-acetamido-3-mercaptopropanoate,N-Acetyl-L-cysteine methyl ester
Target: Amino Acids and Derivatives
Bipenquinate
Cat.No: T8332
Synonym:
Target: Dehydrogenase
Tricyclazole
Cat.No: T5955
Synonym: 三环唑,Tricyclazol
Target: Antibacterial
Mildronate dihydrate
Cat.No: T6586
Synonym: Meldonium,米屈肼(二水合物),Mildronate
Target: Others
Clomazone
Cat.No: T19781
Synonym: Gamit,FMC 57020,Command,异恶草松,Dimethazone,Magister
Target: Others
CHS-828
Cat.No: T1998
Synonym: CHS 828,GMX1778
Target: Apoptosis, NAMPT
Salicyl-AMS
Cat.No: T17176
Synonym:
Target: Antibacterial
L-161240
Cat.No: T32490
Synonym: L-161,240
Target: Antibacterial
Etoxazole
Cat.No: T4055
Synonym:
Target: Others
Jarin-1
Cat.No: T15608
Synonym:
Target: Others
Fenclonine
Cat.No: T1447
Synonym: Fenchlonine,PCPA,CP-10188,芬克洛宁,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine
Target: Hydroxylase
PluriSIn 1
Cat.No: T1869
Synonym: 4-吡啶羧酸 2-苯基酰肼,NSC 14613,PluriSIn #1,PluriSln 1
Target: Apoptosis, Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
Meclofenamic acid sodium
Cat.No: T0260
Synonym: Meclofenamate Sodium,Movens,Meclomen,甲氯灭酸钠,Meclonax
Target: Gap Junction Protein, COX
Cholesterol-5α,6α-epoxide
Cat.No: T35973
Synonym: Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176
Target: Others
Uniconazole
Cat.No: T21482
Synonym:
Target: P450, ROS Kinase
Mildronate
Cat.No: T3268
Synonym: Kvaterin,米屈肼,Meldonium,Quaterin
Target: Hydroxylase
L-Gulose
Cat.No: T22352
Synonym:
Target: Others, Endogenous Metabolite
Cat. No. Product Name Target Signaling Pathways
T3816 Velutin

NF-κB; HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism; NF-κB
Velutin 是一种苷元,提取自槲寄生中,能够抑制黑色素生物合成。它利用 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。
T8115 Menthofuran

Others Others
Menthofuran 是一种天然产品。
TN1576 Diallyl disulfide

IL Receptor; NOS; NF-κB Immunology/Inflammation; NF-κB
Diallyl disulfide 能够抑制人角鲨烯单加氧酶,抑制角鲨烯环氧化的 IC50为 400 μM。它也具有抗肿瘤作用,同miR-200b 和miR-22联合使用可增强该作用。
TN6715 7-Ketocholesterol

Others Others
7-Ketocholesterol 是胆固醇的代谢物。
T2919 Sesamin

Fagarol,Fsesamin,芝麻素

Others Others
Sesamin 是多不饱和脂肪酸生物合成中的选择性delta 5 去饱和酶抑制剂,是在芝麻油中存在丰富的木脂素。它对脑缺血具有有效的神经保护作用。
TN2331 Eleutheroside B1

刺五加苷B1

Influenza Virus Microbiology/Virology
Eleutheroside B1是具有广谱抗人流感病毒的一种香豆素。它抑制多种趋化因子基因和流感病毒核蛋白基因的 mRNA 表达。它具有抗病毒、抗流感和抗炎活性,且细胞毒性小。
T4834 Indole-3-acetamide

3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺

Others; Endogenous Metabolite Metabolism; Others
Indole-3-acetamide 是一种 indole-3-acetic acid 的生物合成中间体。其中 Indole-3-acetic acid 是植物生长素类中最常见的天然植物生长激素。
T1589 D-Cycloserine

RO-1-9213,D-环丝氨酸

Others; Antibacterial; Antibiotic; iGluR Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
D-Cycloserine (RO-1-9213) 是一种抗生素,靶向细菌细胞壁肽聚糖生物合成酶。它是一种NMDA 部分激动剂,可以改善认知功能,可研究耐多药结核病。
T7786 Tryptanthrin

DNA gyrase DNA Damage/DNA Repair
Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平,并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
T7132 (Rac)-Brassinazole

BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

P450 Metabolism
(Rac)-Brassinazole 是三唑型化合物,是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T4454 Traumatic Acid

Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid

Antioxidant oxidation-reduction
Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸,从菜豆中分离得到。它可减少膜磷脂的过氧化,并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。
T9086 Deoxythymidine-5'-triphosphate trisodium

dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一,用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T5284 N-​Carbamoyl-​DL-​aspartic acid

氨基甲酰-DL-天(门)冬氨酸,N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid,脲基琥珀酸

Others; Endogenous Metabolite Metabolism; Others
N-​Carbamoyl-​DL-​aspartic acid (Ureidosuccinic acid) 是核酸嘧啶的前体之一。
T8273 4,6-Dioxoheptanoic acid

Succinylacetone,4,6-二氧代庚酸

Others; Endogenous Metabolite Metabolism; Others
4,6-Dioxoheptanoic acid (Succinylacetone) 是血红素生物合成的有效抑制剂。
TN2237 Steviol-19-O-glucoside

Steviol-19-O-Glucoside,甜菊醇-19-葡萄糖苷

Others Others
Steviol-19-O-glucoside 是甜叶菊 Stevia rebuadiana 中甜菊糖苷生物合成途径的天然产物。
T21130 Precocene II

早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683

Others Others
Precocene II (Ageratochromene) 是一种抗异体激素化合物,可抑制保幼激素的生物合成。 Precocene II 具有杀虫、抗真菌、抗菌和抗氧化活性。
T4795 Pimelic acid

Pileric acid,1,7-Heptanedioic acid,庚二酸,1,5-Pentanedicarboxylic acid

Others; Endogenous Metabolite Metabolism; Others
Pimelic acid (1,5-Pentanedicarboxylic acid) 的衍生物能够参与赖氨酸的生物合成。
T8949 UDP-g acid

Others Others
UDP-g acid 是一种用于生产多糖的糖,是抗坏血酸生物合成的中间体。
T2748 Cortodoxone

可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Cortodoxone (11-Desoxycortisol) 是糖皮质类固醇激素,能够氧化为皮质醇。
T1662 5-Aminolevulinic acid hydrochloride

氨基酮戊酸,Hydrangin,5-ALA,5-Aminolevulinic acid HCl,5-氨基乙酰丙酸盐酸盐,ALA hydrochloride

Apoptosis; Mitophagy; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Metabolism
5-Aminolevulinic acid hydrochloride (5-ALA) 是体内血红素生物合成的中间体,也是四吡咯的通用前体。
T8095 O-Acetylserine

O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸

Others; Endogenous Metabolite Metabolism; Others
O-Acetylserine (O-Acetyl-L-serine) 是细菌和植物中半胱氨酸合成过程中的中间体。
T19711 Desmosterol

Desmesterol,24-Dehydrocholesterol

Endogenous Metabolite Metabolism
Desmosterol(24-Dehydrocholesterol) 是一种胆固醇生物合成中间体,抑制巨噬细胞炎症小体活化,防止血管炎症和动脉粥样硬化。
T5875 4-Methoxycinnamic acid

Endogenous Metabolite Metabolism
4-Methoxycinnamic acid 是天然苯丙烷类化合物。
TQ0273 Neopterin

D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤

Endogenous Metabolite Metabolism
Neopterin (D-(+)-Neopterin) 是三磷酸腺苷的一种分解产物,是细胞免疫系统激活的标志物。
T4921 Oxoadipic acid

2-氧代己二酸,2-Oxoadipic acid

Endogenous Metabolite Metabolism
Oxoadipic acid (2-Oxoadipic acid) 是必需氨基酸色氨酸和赖氨酸的一种代谢物。
T4114 Diffractaic Acid

NSC 5901,地弗地衣酸,NSC 685595

Apoptosis; LTR Apoptosis; Immunology/Inflammation
Diffractaic Acid (NSC 685595) 是松萝的主要成分,具有止痛和解热效果,在各种疾病研究中可作为有效的促凋亡剂。
T4923 7-Dehydrocholesterol

Provitamin D3,7-DHC,7-去氢胆固醇

Endogenous Metabolite Metabolism
7-Dehydrocholesterol (Provitamin D3) 是合成胆固醇和维生素 D3的前体。7-Dehydrocholesterol 下调培养的 Smith-Lemi-Opitz 综合征皮肤成纤维细胞中的胆固醇生物合成。
T4972 2'-Deoxycytidine-5'-diphosphate trisodium

dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Endogenous Metabolite Metabolism
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T2739 Shikimic Acid

Shikimate,莽草酸

Others; Endogenous Metabolite Metabolism; Others
Shikimic Acid (Shikimate) 是一种三羟基环己烯羧酸,是在微生物和植物中发现的,芳香族氨基酸生物合成途径的关键代谢中间体。
T5225 Hypotaurine

2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid

Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
Hypotaurine (2-Aminoethanesulfinic acid) 是星形胶质细胞中半胱氨酸生物合成的牛磺酸中间体,是甘氨酸受体 (glycine receptor) 的内源性抑制性氨基酸。Hypotaurine 也是抗氧化剂。
T3324 Lycorine

Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。
T3003 5-hydroxytryptophan

5-羟基色氨酸,NSC-92523

Others; Endogenous Metabolite Metabolism; Others
5-hydroxytryptophan (NSC-92523) 是色氨酸的代谢物,是5-羟色胺直接的前体,是芳香氨基酸脱羧酶底物。
T4731 2'-Deoxycytidine-5'-monophosphoric acid

dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物,形成 dCDP,在磷酸化成 dCTP 后支持 DNA 的生物合成。
T4722 O-Acetyl-L-serine hydrochloride

Others; Endogenous Metabolite Metabolism; Others
O-Acetyl-L-serine hydrochloride 是内源性代谢产物的一种。
T12796 S-Dihydrodaidzein

S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Others Others
S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) 是一种 dihydrodaidzein 的 (S) 型对映体。其中 dihydrodaidzein 是一种可食用性植物雌激素。
T5578 L-Gulono-1,4-lactone

Others; Endogenous Metabolite Metabolism; Others
L-Gulono-1,4-lactone 是一种 L-古洛糖酸-γ-内酯氧化还原酶的作用底物,该酶能促进维生素 C 合成的末步。它是动物、植物和一些原生生物中维生素 C 的直接前体。
T2760 (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate

Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate,双碘酪氨酸

Others; Endogenous Metabolite Metabolism; Others
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate (jodgorgon) 是内源性代谢产物的一种。
T5066 Nε,Nε,Nε-Trimethyllysine chloride

Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride

Others; Endogenous Metabolite Metabolism; Others
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) 是肠道菌群依赖性形成 N,N,N-trimethyl-5-aminovaleric acid (TMAVA) 的前体。
T41054 γ-Glutamyl-S-allylcysteine

L-γ-Glutamyl-(S)-Allyl-Cysteine

Antioxidant oxidation-reduction
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) 是从Allium sativum L.中提取的γ-谷氨酰肽。γ-Glutamyl-S-allylcysteine 具有抗糖化和抗氧化活性,可抑制胆固醇的生物合成。
TN2296 Vinaginsenoside R4

越南参皂苷R4

Others Others
Vinaginsenoside R4 是分离自水培人参的叶子中。它能够抑制黑色素的生物合成,并增强斑马鱼的色素沉着,对 melan-a 细胞没有任何细胞毒性作用。
T3948 Undecanoic acid

Hendecanoic acid,十一烷酸,Undecylic acid

Others; Endogenous Metabolite; Antifungal Metabolism; Microbiology/Virology; Others
Undecanoic acid (Hendecanoic acid) 是一种具有抗真菌特性的一元羧酸,可抑制红色葡萄球菌中细胞外角蛋白酶、脂肪酶的产生和几种磷脂的生物合成。
T0146 Tioconazole

UK-20349,Vagistat,噻康唑

Antibiotic; Antifection; Antifungal Microbiology/Virology
Tioconazole (Vagistat) 是一种广谱性的抗真菌咪唑衍生物。它抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。
T5573 Coenzyme Q9

辅酶Q9,Ubiquinone Q9,Ubiquinone 9,CoQ9

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Coenzyme Q9 (Ubiquinone 9) 是啮齿类动物泛醌的主要形式,是电子传递链中的一种双亲分子组分,具有内源性抗氧化剂的作用。它可减轻糖尿病引起的抗氧化防御机制的下降,改善左心室功能,减少心肌梗死面积和心肌细胞凋亡。
T4S1616 Sanggenon D

Sanggenone D

GABA Receptor; Antibiotic Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Sanggenon D (Sanggenone D) 是来自桑白皮的小分子化合物,是GABA(A)受体调节剂,具有抗氧化抗菌活性,抑制乳腺癌细胞增殖,通过调节脂肪酸生物合成系统来抑制金黄色葡萄球菌的生长。
T7040 Angiotensin II human

DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II

Apoptosis; RAAS Apoptosis; Endocrinology/Hormones
Angiotensin II human (Ang II) 是一种生物活性肽,一种血管收缩剂。Angiotensin II 可以与 AT1R 和 AT2R 相互作用,调节人类血压,刺激交感神经,增加醛固酮生物合成和肾脏活动。
T6702 Terbinafine

Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Terbinafine (TDT 067) 是念珠菌属的角鲨烯环氧化酶有效的非竞争性抑制剂,Ki 值为 30 nM。它具有抗真菌感染活性。
T21065 Artemisitene

Others Others
Artemisitene 是青蒿素的氧化形式,是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质,包括青蒿素 B、青蒿素、青蒿酸等。
T4939 Indole-3-pyruvic acid

3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid

Others Others
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) 是一种参与Indole-3-acetic acid 生物合成的化合物,Indole-3-acetic acid 是一种植物激素,在调节生长和对环境变化的反应中起重要作用。
TN6993 Benzylideneacetone

Benzalacetone

Phospholipase; Endogenous Metabolite Metabolism
Benzylideneacetone 是由昆虫致病细菌 Xenorhabdus nematophila 产生的单萜类化合物,是磷脂酶A2(PLA2)抑制剂,对类花生酸生物合成具有抑制作用,可增强小菜蛾木霉菌的杆状病毒致病性。
TN1051 1-Caffeoylquinic acid

金银花,1-咖啡酰奎宁酸

NF-κB NF-κB
1-Caffeoylquinic acid 是一种有效的NF-κB 抑制剂,对 p105 的 RH 结构域显示高结合亲和力,Ki= 0.002 μM,结合能为 1.50 Kcal/mol。它抑制PD-1/PD-L1相互作用。它具有抗氧化应激能力。
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天然产物

Velutin
Cat.No: T3816
Synonym:
Target: NF-κB, HIF/HIF Prolyl-Hydroxylase
Menthofuran
Cat.No: T8115
Synonym:
Target: Others
Diallyl disulfide
Cat.No: TN1576
Synonym:
Target: IL Receptor, NOS, NF-κB
7-Ketocholesterol
Cat.No: TN6715
Synonym:
Target: Others
Sesamin
Cat.No: T2919
Synonym: Fagarol,Fsesamin,芝麻素
Target: Others
Eleutheroside B1
Cat.No: TN2331
Synonym: 刺五加苷B1
Target: Influenza Virus
Indole-3-acetamide
Cat.No: T4834
Synonym: 3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺
Target: Others, Endogenous Metabolite
D-Cycloserine
Cat.No: T1589
Synonym: RO-1-9213,D-环丝氨酸
Target: Others, Antibacterial, Antibiotic, iGluR
Tryptanthrin
Cat.No: T7786
Synonym:
Target: DNA gyrase
(Rac)-Brassinazole
Cat.No: T7132
Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑
Target: P450
Traumatic Acid
Cat.No: T4454
Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid
Target: Antioxidant
Deoxythymidine-5'-triphosphate trisodium
Cat.No: T9086
Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt
Target: DNA/RNA Synthesis
N-​Carbamoyl-​DL-​aspartic acid
Cat.No: T5284
Synonym: 氨基甲酰-DL-天(门)冬氨酸,N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid,脲基琥珀酸
Target: Others, Endogenous Metabolite
4,6-Dioxoheptanoic acid
Cat.No: T8273
Synonym: Succinylacetone,4,6-二氧代庚酸
Target: Others, Endogenous Metabolite
Steviol-19-O-glucoside
Cat.No: TN2237
Synonym: Steviol-19-O-Glucoside,甜菊醇-19-葡萄糖苷
Target: Others
Precocene II
Cat.No: T21130
Synonym: 早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683
Target: Others
Pimelic acid
Cat.No: T4795
Synonym: Pileric acid,1,7-Heptanedioic acid,庚二酸,1,5-Pentanedicarboxylic acid
Target: Others, Endogenous Metabolite
UDP-g acid
Cat.No: T8949
Synonym:
Target: Others
Cortodoxone
Cat.No: T2748
Synonym: 可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol
Target: Glucocorticoid Receptor, Endogenous Metabolite
5-Aminolevulinic acid hydrochloride
Cat.No: T1662
Synonym: 氨基酮戊酸,Hydrangin,5-ALA,5-Aminolevulinic acid HCl,5-氨基乙酰丙酸盐酸盐,ALA hydrochloride
Target: Apoptosis, Mitophagy, Endogenous Metabolite, Autophagy
O-Acetylserine
Cat.No: T8095
Synonym: O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸
Target: Others, Endogenous Metabolite
Desmosterol
Cat.No: T19711
Synonym: Desmesterol,24-Dehydrocholesterol
Target: Endogenous Metabolite
4-Methoxycinnamic acid
Cat.No: T5875
Synonym:
Target: Endogenous Metabolite
Neopterin
Cat.No: TQ0273
Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤
Target: Endogenous Metabolite
Oxoadipic acid
Cat.No: T4921
Synonym: 2-氧代己二酸,2-Oxoadipic acid
Target: Endogenous Metabolite
Diffractaic Acid
Cat.No: T4114
Synonym: NSC 5901,地弗地衣酸,NSC 685595
Target: Apoptosis, LTR
7-Dehydrocholesterol
Cat.No: T4923
Synonym: Provitamin D3,7-DHC,7-去氢胆固醇
Target: Endogenous Metabolite
2'-Deoxycytidine-5'-diphosphate trisodium
Cat.No: T4972
Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐
Target: Endogenous Metabolite
Shikimic Acid
Cat.No: T2739
Synonym: Shikimate,莽草酸
Target: Others, Endogenous Metabolite
Hypotaurine
Cat.No: T5225
Synonym: 2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid
Target: Chloride channel, Endogenous Metabolite
Lycorine
Cat.No: T3324
Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱
Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase
5-hydroxytryptophan
Cat.No: T3003
Synonym: 5-羟基色氨酸,NSC-92523
Target: Others, Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphoric acid
Cat.No: T4731
Synonym: dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate
Target: Others, Endogenous Metabolite
O-Acetyl-L-serine hydrochloride
Cat.No: T4722
Synonym:
Target: Others, Endogenous Metabolite
S-Dihydrodaidzein
Cat.No: T12796
Synonym: S-二氢大豆苷元,(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Target: Others
L-Gulono-1,4-lactone
Cat.No: T5578
Synonym:
Target: Others, Endogenous Metabolite
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate
Cat.No: T2760
Synonym: Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate,双碘酪氨酸
Target: Others, Endogenous Metabolite
Nε,Nε,Nε-Trimethyllysine chloride
Cat.No: T5066
Synonym: Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride
Target: Others, Endogenous Metabolite
γ-Glutamyl-S-allylcysteine
Cat.No: T41054
Synonym: L-γ-Glutamyl-(S)-Allyl-Cysteine
Target: Antioxidant
Vinaginsenoside R4
Cat.No: TN2296
Synonym: 越南参皂苷R4
Target: Others
Undecanoic acid
Cat.No: T3948
Synonym: Hendecanoic acid,十一烷酸,Undecylic acid
Target: Others, Endogenous Metabolite, Antifungal
Tioconazole
Cat.No: T0146
Synonym: UK-20349,Vagistat,噻康唑
Target: Antibiotic, Antifection, Antifungal
Coenzyme Q9
Cat.No: T5573
Synonym: 辅酶Q9,Ubiquinone Q9,Ubiquinone 9,CoQ9
Target: Apoptosis, Endogenous Metabolite
Sanggenon D
Cat.No: T4S1616
Synonym: Sanggenone D
Target: GABA Receptor, Antibiotic
Angiotensin II human
Cat.No: T7040
Synonym: DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II
Target: Apoptosis, RAAS
Terbinafine
Cat.No: T6702
Synonym: Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067
Target: Antibacterial, Antibiotic, Antifungal
Artemisitene
Cat.No: T21065
Synonym:
Target: Others
Indole-3-pyruvic acid
Cat.No: T4939
Synonym: 3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid
Target: Others
Benzylideneacetone
Cat.No: TN6993
Synonym: Benzalacetone
Target: Phospholipase, Endogenous Metabolite
1-Caffeoylquinic acid
Cat.No: TN1051
Synonym: 金银花,1-咖啡酰奎宁酸
Target: NF-κB
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Cat. No. Product Name Species Expression System
TMPH-00745 TsaE Protein, E. coli, Recombinant

t(6)A37 threonylcarbamoyladenosine biosynthesis pro...

E. coli E. coli
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro.
TMPH-03525 Cap5A Protein, S. aureus, Recombinant (His)

Capsular polysaccharide type 5 biosynthesis protein...

Staphylococcus aureus E. coli
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. Cap5A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P95695.
TMPH-02079 SPTLC2 Protein, Human, Recombinant (His & SUMO)

Long chain base biosynthesis protein 2a,Long chain ...

Human E. coli
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb...
TMPH-01613 LIPT1 Protein, Human, Recombinant (His)

Lipoate biosynthesis protein,Lipoyl amidotransferas...

Human E. coli
Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
TMPH-00188 BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc)

Adenosylmethionine-8-amino-7-oxononanoate aminotransferase B...

Bacteroides fragilis E. coli
Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The p...
TMPH-03170 PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Pyoverdin biosynthesis protein A,L-ornithine N(5)-h...

Pseudomonas aeruginosa E. coli
PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.5 kDa and the accession number is Q51548.
TMPJ-00932 PBLD Protein, Human, Recombinant (His)

MAWBP,MAWD-Binding Protein,PBLD,MAWDBP,Unknown Protein 32 Fr...

Human E. coli
Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is involved in multiple basic cellular functions. The expression of PBLD can be increased in several disease processes, including insulin resistance, folate deficiency and hypotension.
TMPY-01736 COX-2 Protein, Human, Recombinant (His)

GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...

Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPY-02801 PHGDH Protein, Human, Recombinant (His)

phosphoglycerate dehydrogenase,HEL-S-113,3PGDH,NLS1,PHGDHD,P...

Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PH...
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His)

abhydrolase domain containing 4,ABH4

Human Baculovirus Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa...
TMPH-02652 FGF-15 Protein, Mouse, Recombinant (His & SUMO)

Fibroblast growth factor 15,Fgf15

Mouse E. coli
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
TMPH-02293 UGDH Protein, Human, Recombinant (His & SUMO)

UDP-glucose 6-dehydrogenase,UGDH

Human E. coli
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development.
TMPH-00572 ACP Protein, E. coli, Recombinant (His & SUMO)

acpP,Fatty acid synthase acyl carrier protein,Cytosolic-acti...

E. coli E. coli
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
TMPH-00563 3-demethoxyubiquinol 3-hydroxylase Protein, E. coli, Recombinant (His)

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase,...

E. coli E. coli
Catalyzes the hydroxylation of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
TMPH-00591 SpeA Protein, E. coli, Recombinant (His)

speA,Biosynthetic arginine decarboxylase

E. coli E. coli
Catalyzes the biosynthesis of agmatine from arginine.
TMPH-00020 Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His)

Elongation factor Tu,EF-Tu

Acinetobacter baumannii P. pastoris (Yeast)
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
TMPH-03584 Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc)

Shikimate dehydrogenase (NADP(+)),aroE

Staphylococcus epidermidis E. coli
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also use NAD to oxidize shikimate. Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5HNV1.
TMPH-01395 QPCTL Protein, Human, Recombinant (His & SUMO)

isoQC,Glutaminyl-peptide cyclotransferase-like protein,Golgi...

Human E. coli
Responsible for the biosynthesis of pyroglutamyl peptides. QPCTL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.5 kDa and the accession number is Q9NXS2.
TMPH-00564 FabG Protein, E. coli, Recombinant (His & Myc)

Beta-Ketoacyl-acyl carrier protein reductase,fabG,Beta-ketoa...

E. coli E. coli
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
TMPH-01812 SEPSECS Protein, Human, Recombinant (His)

SLA-p35,SEPSECS,Sep-tRNA:Sec-tRNA synthase,Selenocysteine sy...

Human P. pastoris (Yeast)
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. SEPSECS Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.5 kDa and the accession number is Q9HD40.
TMPH-02378 LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)

UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[R-3-hy...

Klebsiella pneumoniae E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPH-03048 LpxA Protein, MenC, Recombinant (His)

lpxA,Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-...

MenB E. coli
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
TMPJ-01265 PPC-DC Protein, Human, Recombinant (aa 1-204, His)

Phosphopantothenoylcysteine Decarboxylase,PPC-DC,PPCDC,COAC

Human E. coli
Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and ...
TMPY-03507 PPC-DC Protein, Human, Recombinant (E. coli, His)

coaC,MDS018,PPC-DC,phosphopantothenoylcysteine decarboxylase

Human E. coli
PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. This process include several steps: the phosphorylation of pantothenate, the conversion of 4’-hosphopantothenate to 4''-phosphopantetheine, the adenylation by pho...
TMPH-00555 LpxC Protein, E. coli, Recombinant (His)

lpxC,UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[R...

E. coli E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPY-00481 AKR1C4 Protein, Human, Recombinant (His)

aldo-keto reductase family 1, member C4,3-alpha-HSD,DD4,CHDR...

Human E. coli
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, an...
TMPH-00602 MetC Protein, E. coli, Recombinant (His)

Cysteine lyase MetC,Beta-cystathionase MetC,metC,Cystathioni...

E. coli E. coli
Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under certain growth conditions, exhibits significant alanine racemase coactivity.
TMPH-03453 GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)

Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 su...

Saccharomyces cerevisiae E. coli
Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. GPI3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.8 kDa and the accession number is P32363.
TMPH-03180 LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

UDP-3-O-acyl-N-acetylglucosamine deacetylase,lpxC,UDP-3-O-[R...

Pseudomonas aeruginosa E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.4 kDa and the accession number is P47205.
TMPY-01948 COQ7 Protein, Human, Recombinant (His)

CLK1,coenzyme Q7 homolog, ubiquinone (yeast),CAT5,CLK-1

Human HEK293 Cells
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. Th...
TMPY-03810 GALNT2 Protein, Human, Recombinant (His)

GalNAc-T2,polypeptide N-acetylgalactosaminyltransferase 2

Human HEK293 Cells
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broa...
TMPH-03519 ACP Protein, S. aureus, Recombinant (His)

Cytosolic-activating factor,Fatty acid synthase acyl carrier...

Staphylococcus aureus P. pastoris (Yeast)
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPH-02958 Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)

Tryptophan 5-monooxygenase 1,Tryptophan 5-hydroxylase 1,Tph1

Mouse E. coli
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.3 kDa and the accession number is P17532.
TMPH-03520 ACP Protein, S. aureus, Recombinant (His & SUMO)

acpP,Cytosolic-activating factor,Fatty acid synthase acyl ca...

Staphylococcus aureus E. coli
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPH-03447 ERG11 Protein, S. cerevisiae, Recombinant (GST)

Ergosterol biosynthetic protein 11,Cytochrome P450 51,ERG11,...

Saccharomyces cerevisiae E. coli
Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. ERG11 Protein, S. cerevisiae, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 29.1 kDa and the accession number is P10614.
TMPH-01813 SEPSECS Protein, Human, Recombinant (E. coli, His)

Selenocysteine synthase,O-phosphoseryl-tRNA(Sec) selenium tr...

Human E. coli
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. SEPSECS Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 53.4 kDa and the accession number is Q9HD40.
TMPH-00795 Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc)

murI,Glutamate racemase

Helicobacter pylori E. coli
Provides the (R)-glutamate required for cell wall biosynthesis. Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.9 kDa and the accession number is B5Z6S2.
TMPK-00944 ST3GAL4 Protein, Human, Recombinant (HA, His)

STZSIAT4,ST-4,SIAT4,ST3GAL4,SAT3,CGS23,SIAT4C,Gal-NAc 6S,NAN...

Human HEK293 Cells
ST3GAL4 gene expression is altered in different cancer types, including cervical cancer. Several mRNA transcripts have been reported for this gene. ST3GAL4 encodes for β‑galactosidase α‑2,3‑sialyltransferase 4, involved in the biosynthesis of the tumour antigens sLe(x) and sulfo‑sLe(x).
TMPY-00569 B3GAT3 Protein, Human, Recombinant (His)

beta-1,3-glucuronyltransferase 3,glcUAT-I,GLCATI,β-1,3-glucu...

Human E. coli
B3GAT3, encoding beta-1,3-glucuronyltransferase 3, has an important role in proteoglycan biosynthesis. Homozygous B3GAT3 mutations have been associated with short stature, skeletal deformities, and congenital heart defects. There is a novel B3GAT3-related disorder with craniosynostosis and bone fragility, due to a unique homozygous mutation in B3GAT3.
TMPH-01603 Lanosterol synthase/LSS Protein, Human, Recombinant (His)

Lanosterol synthase,LSS,2,3-epoxysqualene--lanosterol cyclas...

Human E. coli
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
TMPH-00648 LapB Protein, E. coli, Recombinant (His)

Lipopolysaccharide assembly protein B,lapB,Lipopolysaccharid...

E. coli E. coli
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
TMPH-03017 CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Cytochrome P450-14DM,Sterol 14alpha-demethylase,Sterol 14-al...

Mycobacterium tuberculosis Baculovirus Insect Cells
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
TMPH-03742 EEF1A1 Protein, Cricetulus griseus, Recombinant (His)

EEF1A,Elongation factor 1-alpha 1,eEF1A-1,EF-1-alpha-1,EF-Tu...

Chinese hamster E. coli
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.
TMPH-01224 Dihydrofolate reductase Protein, Human, Recombinant (His)

DHFR,Dihydrofolate reductase

Human E. coli
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
TMPJ-00473 QPRTase Protein, Human, Recombinant (His)

QPRTase,QAPRTase,Nicotinate-Nucleotide Pyrophosphorylase [Ca...

Human E. coli
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quin...
TMPH-02679 QPCT Protein, Mouse, Recombinant (His)

Glutaminyl cyclase,Glutaminyl-tRNA cyclotransferase,Qpct,Glu...

Mouse P. pastoris (Yeast)
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is Q9CYK2.
TMPH-03179 LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetyla...

Pseudomonas aeruginosa E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.4 kDa and the accession number is A6VB79.
TMPY-03452 PTS Protein, Human, Recombinant (His)

PTPS,PTS,6-pyruvoyltetrahydropterin synthase

Human E. coli
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia....
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重组蛋白

TsaE Protein, E. coli, Recombinant
Cat.No: TMPH-00745
Species: E. coli
Expression System: E. coli
Cap5A Protein, S. aureus, Recombinant (His)
Cat.No: TMPH-03525
Species: Staphylococcus aureus
Expression System: E. coli
SPTLC2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02079
Species: Human
Expression System: E. coli
LIPT1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01613
Species: Human
Expression System: E. coli
BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc)
Cat.No: TMPH-00188
Species: Bacteroides fragilis
Expression System: E. coli
PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Cat.No: TMPH-03170
Species: Pseudomonas aeruginosa
Expression System: E. coli
PBLD Protein, Human, Recombinant (His)
Cat.No: TMPJ-00932
Species: Human
Expression System: E. coli
COX-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
PHGDH Protein, Human, Recombinant (His)
Cat.No: TMPY-02801
Species: Human
Expression System: E. coli
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
ABHD4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01460
Species: Human
Expression System: Baculovirus Insect Cells
FGF-15 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02652
Species: Mouse
Expression System: E. coli
UGDH Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02293
Species: Human
Expression System: E. coli
ACP Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00572
Species: E. coli
Expression System: E. coli
3-demethoxyubiquinol 3-hydroxylase Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00563
Species: E. coli
Expression System: E. coli
SpeA Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00591
Species: E. coli
Expression System: E. coli
Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His)
Cat.No: TMPH-00020
Species: Acinetobacter baumannii
Expression System: P. pastoris (Yeast)
Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc)
Cat.No: TMPH-03584
Species: Staphylococcus epidermidis
Expression System: E. coli
QPCTL Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01395
Species: Human
Expression System: E. coli
FabG Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00564
Species: E. coli
Expression System: E. coli
SEPSECS Protein, Human, Recombinant (His)
Cat.No: TMPH-01812
Species: Human
Expression System: P. pastoris (Yeast)
LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)
Cat.No: TMPH-02378
Species: Klebsiella pneumoniae
Expression System: E. coli
LpxA Protein, MenC, Recombinant (His)
Cat.No: TMPH-03048
Species: MenB
Expression System: E. coli
PPC-DC Protein, Human, Recombinant (aa 1-204, His)
Cat.No: TMPJ-01265
Species: Human
Expression System: E. coli
PPC-DC Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPY-03507
Species: Human
Expression System: E. coli
LpxC Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00555
Species: E. coli
Expression System: E. coli
AKR1C4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00481
Species: Human
Expression System: E. coli
MetC Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00602
Species: E. coli
Expression System: E. coli
GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)
Cat.No: TMPH-03453
Species: Saccharomyces cerevisiae
Expression System: E. coli
LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Cat.No: TMPH-03180
Species: Pseudomonas aeruginosa
Expression System: E. coli
COQ7 Protein, Human, Recombinant (His)
Cat.No: TMPY-01948
Species: Human
Expression System: HEK293 Cells
GALNT2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03810
Species: Human
Expression System: HEK293 Cells
ACP Protein, S. aureus, Recombinant (His)
Cat.No: TMPH-03519
Species: Staphylococcus aureus
Expression System: P. pastoris (Yeast)
Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02958
Species: Mouse
Expression System: E. coli
ACP Protein, S. aureus, Recombinant (His & SUMO)
Cat.No: TMPH-03520
Species: Staphylococcus aureus
Expression System: E. coli
ERG11 Protein, S. cerevisiae, Recombinant (GST)
Cat.No: TMPH-03447
Species: Saccharomyces cerevisiae
Expression System: E. coli
SEPSECS Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01813
Species: Human
Expression System: E. coli
Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc)
Cat.No: TMPH-00795
Species: Helicobacter pylori
Expression System: E. coli
ST3GAL4 Protein, Human, Recombinant (HA, His)
Cat.No: TMPK-00944
Species: Human
Expression System: HEK293 Cells
B3GAT3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00569
Species: Human
Expression System: E. coli
Lanosterol synthase/LSS Protein, Human, Recombinant (His)
Cat.No: TMPH-01603
Species: Human
Expression System: E. coli
LapB Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00648
Species: E. coli
Expression System: E. coli
CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Cat.No: TMPH-03017
Species: Mycobacterium tuberculosis
Expression System: Baculovirus Insect Cells
EEF1A1 Protein, Cricetulus griseus, Recombinant (His)
Cat.No: TMPH-03742
Species: Chinese hamster
Expression System: E. coli
Dihydrofolate reductase Protein, Human, Recombinant (His)
Cat.No: TMPH-01224
Species: Human
Expression System: E. coli
QPRTase Protein, Human, Recombinant (His)
Cat.No: TMPJ-00473
Species: Human
Expression System: E. coli
QPCT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02679
Species: Mouse
Expression System: P. pastoris (Yeast)
LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03179
Species: Pseudomonas aeruginosa
Expression System: E. coli
PTS Protein, Human, Recombinant (His)
Cat.No: TMPY-03452
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0111 11-Deoxycortisol-2,2,4,6,6-d5

11-Deoxycortisol-2,2,4,6,6-d5 是 11-Deoxycortisol 的氘代化合物。11-Deoxycortisol 的 CAS 号为 152-58-9。Cortodoxone是糖皮质类固醇激素,能够氧化为皮质醇。
T36384 DL-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N

L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
T69395 Nicotinamide-d4

Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl...
TMID-0254 Linalool-d3

Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物,是竞争性NMDA受体拮抗剂,具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤,具有镇痛、抗菌和抗炎的特性。

同位素标记化合物

11-Deoxycortisol-2,2,4,6,6-d5
Cat.No: TMID-0111
Synonym:
Target:
DL-Tyrosine-13C9,15N
Cat.No: T36384
Synonym: L-Tyrosine-13C9,15N
Target:
Nicotinamide-d4
Cat.No: T69395
Synonym:
Target:
Linalool-d3
Cat.No: TMID-0254
Synonym:
Target:
TargetMol Loading
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