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PS20 Protein, Mouse, Recombinant (His)

产品编号 TMPK-01173

PS20 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 21.9 kDa and the accession number is Q9ESH5.

PS20 Protein, Mouse, Recombinant (His)

PS20 Protein, Mouse, Recombinant (His)

产品编号 TMPK-01173
PS20 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 21.9 kDa and the accession number is Q9ESH5.
规格价格库存数量
100 μg¥ 3,1005日内发货
500 μg¥ 12,4005日内发货
1 mg¥ 20,7005日内发货
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生物活性

生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
PS20 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 21.9 kDa and the accession number is Q9ESH5.
种属
Mouse
表达系统
E. coli
标签N-His
蛋白编号Q9ESH5
别名
Wfdc1,Ps20
蛋白构建
Gln24-Pro211
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量21.9 kDa (predicted). The protein migrates to 27-30 kDa based on Tris-Bis PAGE result.
内毒素< 1 EU/μg by the LAL method.
缓冲液Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
存储
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.

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