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Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)

产品编号 TMPH-02366

Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239.

Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)

Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)

产品编号 TMPH-02366
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239.
规格价格库存数量
20 μg¥ 2,29020日内发货
100 μg¥ 4,32020日内发货
1 mg¥ 14,60020日内发货
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生物活性

生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239.
种属
JUNV
表达系统
E. coli
标签N-6xHis-SUMO
蛋白编号P14239
别名
Nucleocapsid protein,Protein N,N,Nucleoprotein
氨基酸序列
MAHSKEVPSFRWTQSLRRGLSQFTQTVKSDVLKDAKLIADSIDFNQVAQVQRALRKTKRGEEDLNKLRDLNKEVDRLMSMRSVQRNTVFKAGDLGRVERMELASGLGNLKTKFRRAETGSQGVYMGNLSQSQLAKRSEILRTLGFQQQGTGGNGVVRVWDVKDPSKLNNQFGSVPALTIACMTVQGGETMNSVIQALTSLGLLYTVKYPNLSDLDRLTQEHDCLQIVTKDESSINISGYNFSLSAAVKAGASILDDGNMLETIRVTPDNFSSLIKSTIQVKRREGMFIDEKPGNRNPYENLLYKLCLSGDGWPYIGSRSQIIGRSWDNTSIDLTRKPVAGPRQPEKNGQNLRLANLTEIQEAVIREAVGKLDPTNTLWLDIEGPATDPVEMALFQPAGSKYIHCFRKPHDEKGFKNGSRHSHGILMKDIEDAMPGVLSYVIGLLPPDMVVTTQGSDDIRKLFDLHGRRDLKLVDVRLTSEQARQFDQQVWEKFGHLCKHHNGVVVSKKKRDKDAPFKLASSEPHCALLDCIMFQSVLDGKLYEEELTPLLPPSLLFLPKAAYAL
蛋白构建
1-564 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
分子量79.0 kDa (predicted)
缓冲液Tris-based buffer, 50% glycerol
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.

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