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22-SLF是一种通过FBXO22依赖机制实现FK506结合蛋白12 (FKBP12) 降解的PROTAC降解剂,其DC50值为0.5 µM.此外,22-SLF还能降解其他内源性蛋白质,如BRD4和EML4-ALK融合蛋白 (EML4-ALK fusion protein).
22-SLF是一种通过FBXO22依赖机制实现FK506结合蛋白12 (FKBP12) 降解的PROTAC降解剂,其DC50值为0.5 µM.此外,22-SLF还能降解其他内源性蛋白质,如BRD4和EML4-ALK融合蛋白 (EML4-ALK fusion protein).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | 22-SLF is a PROTAC degrader that operates by FBXO22-dependent degradation of FK506 Binding Protein 12 (FKBP12) with a DC50 of 0.5 µM. Additionally, 22-SLF can degrade other endogenous proteins, such as BRD4 and the EML4-ALK fusion protein (EML4-ALK fusion protein). |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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