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48

抑制剂 & 化合物

5

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Cat. No. Product Name
L1710 抗COVID-19化合物库

1133 compounds
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;

化合物库

抗COVID-19化合物库
Cat.No: L1710
Compounds: 1133
Cat. No. Product Name Target Signaling Pathways
T33626 Nelipepimut-S

NeuVax vaccine,E75 peptide,NeuVax

Nelipepimut-S, as an immunogenic peptide from the HER2 protein, is highly expressed in breast cancer.
T9520 ALC-0159

Others Others
ALC-0159 是聚乙二醇的脂质结合物,是一种疫苗赋形剂。
T20293 Phenoxyethanol

NSC 1864,乙二醇苯醚,NSC-1864,NSC1864

Others; Antibacterial Microbiology/Virology; Others
Phenoxyethanol (NSC-1864) 是广谱抗菌剂,被用作化妆品、疫苗和纺织品中的防腐剂。它是呼吸作用氧化磷酸化的解偶联剂,竞争性地抑制苹果酸脱氢酶。
TP1938 RS 09

TLR Immunology/Inflammation
RS 09 是一种 LPS 肽模拟物,是 TLR4 激动剂佐剂,可在疫苗环境中增加抗体产量。
T74240 Vaxfectin

Liposome Metabolism
Vaxfectin 是一种脂质佐剂,可用于蛋白质和肽疫苗的研发。Vaxfectin 可促进疫苗的免疫原性。
T4027 KIN1148

Influenza Virus Microbiology/Virology
KIN1148 是一种新型小分子佐剂,是IRF3激动剂,用于增强流感疫苗效率。
T14513 BBIQ

TLR Immunology/Inflammation
BBIQ 是一种有效且选择性的 toll 样受体 7 (TLR7) 激动剂,对人 TLR7 的 EC50 为 59.1 nM。BBIQ 还是一种功能强大的疫苗佐剂,可增强机体的先天免疫应答。
T8886 NITD-2

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂,可抑制 DENV RdRp 介导的 RNA 延伸。
T9277 ALC-0315

Others Others
ALC-0315是一种可电离的氨基脂质,已与其他脂质组合用于形成脂质纳米颗粒。脂质纳米颗粒已经用于 mRNA (COVID-19) 疫苗的研究。
T35941 DC-Chol hydrochloride

​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate

Beta Amyloid Neuroscience
DC-Chol hydrochloride(DC-Cholesterol hydrochloride) 在适当的实验条件下能抑制 Aβ40 纤维的形成且以剂量依赖性的方式显著抑制氧化hCT的淀粉样蛋白形成。DC-Chol hydrochloride可诱导改善和平衡的免疫力,能够促进乙型肝炎疫苗的研究。
TP1166 ZINC77292789

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

Others Others
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) 是制备基于三聚体 MUC1 免疫显性基序抗原的候选抗癌疫苗的起始材料,可制备含有 βGalNAc-​Thr 作为 Tn 抗原异构体的合成 MUC1 糖肽,可诱导针对肿瘤细胞的抗体产生。
T19590 Trehalose 6-behenate

Others Others
Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.
TP2380 Elpamotide

Elpamotide is a vaccine consisting of a VEGFR2-169 peptide.
T38550 Onilcamotide

Onilcamotide, a cancer vaccine derived from the C-terminal peptide of the RhoC protein, exhibits potential immunomodulating and antineoplastic activities.
T38567 STh

STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.
T84676 CoPoP

Cobalt Porphyrin-Phospholipid

Others Others
CoPoP是用于肿瘤研究的脂质体疫苗佐剂。
T19410 M2e, human

Others Others
M2e, human, a vaccine candidate for human influenza A, encompasses the 23 extracellular residues of M2 (the third integral membrane protein of influenza A) and exhibits remarkable conservation across all strains, highlighting its potential as a broadly protective option.
T82462 Enterotoxin STp (E. coli)

Enterotoxin STp (E. coli), 热稳定肠毒素,适用于疫苗研究领域。
T81645 NPNA hexamer

NPNA hexamer是一种与疟疾研究和孢子疫苗开发相关的肽。
T75270 Genevant CL1

Others Others
Genevant CL1 是一种脂质,可用于 mRNA 脂质纳米颗粒 (LNP) 疫苗递送。
T38619 GSK1795091

CRX-601

Others Others
GSK1795091 (CRX-601) is a synthetic TLR4 agonist and immunologic stimulator with demonstrated antitumor activity. It serves as a vaccine adjuvant, enhancing both mucosal and systemic immunity to influenza virus vaccines.
T72016 ST101036

Others Others
MC activators have recently been described as safe and effective vaccine adjuvants. ST101036 exhibited high degranulation potency in both human and mouse MCs.
T82930 Autoinducing Peptide I

Autoinducing Peptide I为金黄色葡萄球菌分泌的环状八肽,主要用于疫苗研究领域。
T38636 Monophosphoryl lipid A

Glucopyranosyl lipid A

Others Others
Monophosphoryl lipid A (MPLA), also known as Glucopyranosyl lipid A, is an agonist of toll-like receptor 4. Derived from the cell wall of nonpathogenic Salmonella, MPLA is a valuable compound for research on immunization and vaccine development.
T38936 KRAS G13D peptide, 25 mer

KRAS G13D peptide, 25 mer

KRAS G13D peptide, a 25-mer sequence, is derived from the KRAS activating oncogene mutation and serves as an immune potentiator. This peptide possesses immunogenic properties and can be utilized for the development of a KRAS vaccine.
T75027 G0-C14

Others Others
G0-C14,一种阳离子类脂烷基修饰的聚氨基胺(PAMAM)树状大分子,适用于巨噬细胞靶向纳米颗粒(NPs)系列的制备,并可用于活性分子与疫苗递送。
T83224 AADvac 1

AADvac1 是一款针对Tau(294–305)的阿尔茨海默病肽疫苗,其通过与KLH缀合,表现出生物活性。
T82048 IRGRILHDGAYSLTLQGLGIH

IRGRILHDGAYSLTLQGLGIH是一种针对大鼠HER2/neu的多表位II类肽。它主要应用于HER2-DC1疫苗的II类研究领域。
T81112 SPPHPSPAFSPAFDNLYYWDQ

SPPHPSPAFSPAFDNLYYWDQ 为多表位 II 类大鼠HER2/neu 肽,适用于 HER2-DC1 II 类疫苗研究。
T81111 SPPHPSPAFSPAFDNLYYWDQ TFA

SPPHPSPAFSPAFDNLYYWDQ TFA,一种II类大鼠HER2/neu多表位肽,应用于II类HER2-DC1疫苗的研究。
T72688 STING agonist-20

Others Others
STINGagonist-20 是一种有效的STING 激动剂,用于合成 XMT-2056。STINGagonist-20 可作为疫苗佐剂,用于癌症以及其他炎症,免疫性疾病的研究。
T74916 ODN M362

Others Others
ODN M362 是一种 C 类寡核苷酸,是 TLR-9激动剂,可用作疫苗佐剂。ODN M362 诱导癌细胞凋亡(apoptosis)。
T74902 ODN 1018

Others Others
ODN 1018 (1018 ISS)为一种寡脱氧核苷酸,兼具TLR-9激动剂与合成免疫刺激序列的特性,广泛应用作疫苗佐剂。序列为5′-TGACTGTGAACGTTCGAGATGA-3′。
T74909 ODN 2395

Others Others
ODN 2395为C类寡核苷酸,作为疫苗佐剂和TLR9激动剂应用。其序列为5'-tcgtcgttttcggcgc:gcgccg-3'。(注:碱基为硫代磷,ODN 2395特征为包含部分回文序列cggcgc:gcgccg)
T74315 16:0 EPC chloride

Others Others
16:0 EPC chloride,一种P-O-乙基衍生的饱和阳离子脂质,可用作DNA与RNA转染剂,亦作为疫苗制备及促进药物递送的辅助佐剂。
T74903 ODN 1668

Others Others
ODN 1668,一种B类CpG ODN(寡脱氧核苷酸),作为TLR-9激动剂,充当免疫刺激序列并可用作疫苗佐剂。序列为5’-tccatgacgttcctgatgct-3’。
T74910 ODN 24888

Others Others
ODN 24888 是一种鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN),对TLR7/TLR9介导的信号通路表现出强烈的抑制作用。ODN 24888 损害 IFN-α 水平和NF-κB 激活,抑制IL-6的释放。ODN 24888 参与免疫和炎症应答,可作为疫苗佐剂使用。
T74908 ODN 2336

Others Others
ODN 2336 是 A 类 CpG ODN(寡脱氧核苷酸),是一种有效的 TLR9激动剂。ODN 2336 诱导 IFN-α 的产生。ODN 2336 上调 IP-10 mRNA 和 IL-18mRNA 的表达。ODN 2336 可用作疫苗的佐剂。
T74905 ODN 2007

Others Others
ODN 2007是一种B类CpG ODN(寡脱氧核苷酸),兼具Toll样受体(TLR)配体功能。作为免疫调节剂和疫苗佐剂,它能够增强哺乳动物、鱼类及人类的免疫反应。其序列为5'-TCGTCGTTGTCGTTTTGTCGTT-3'。
T81388 Propiolactone

Betaprone,β-propiolactone,2-Oxetanone

SARS-CoV Microbiology/Virology
Propiolactone (β-propiolactone; 2-Oxetanone) 作为一种病毒化学灭活剂,能够使病毒失去传染性。以1:1000 (v:v) 的比例与SARS-CoV共孵育,Propiolactone可用于制备流感病毒疫苗中的抑菌剂(Flu-BPL)。
T79707 Cholicamideβ

Necroptosis Apoptosis
Cholicamideβ(compound 6)为自组装小分子癌症疫苗佐剂,能够形成细胞毒性低的病毒样颗粒。该化合物与肽抗原结合,可增强树突状细胞的抗原呈递能力,并激活抗原特异性T细胞反应。Cholicamideβ还能引发细胞凋亡(apoptosis)和坏死(necrosis)。
T76016 M2e, human TFA

M2e, human TFA 由 23 个 M2 (流感病毒A 的第三个完整膜蛋白) 胞外残基组成,在所有人流感病毒 A 株中都有显著的保守性。M2e, human TFA 是一种有效且多用途的疫苗候选,可预防人类流感病毒 A 株。
T74326 αGalCer-RBD

Others Others
αGalCer-RBD 是一种佐剂脂蛋白结合物。αGalCer-RBD 可诱导对 SARS-CoV-2及其变异毒株的有效免疫。αGalCer-RBD 结合物诱导 RBD 特异性、产生细胞因子的 T 细胞发育。αGalCer-RBD 有望成为一种有效的 COVID-19 疫苗候选化合物。α-Galactosylceramide (αGalCer) 是一种有效的不变自然杀伤 T 细胞 (iNKT) 激动剂。
T64277 ODN 1585

Others Others
ODN 1585 是一种有效的 IFN 和 TNFα 产生诱导剂,也是一种 NK (natural killer) 的有效刺激剂,可用做疫苗佐剂。ODN 1585 能够增强 CD8+ T 细胞的功能,包括 CD8+ T 细胞介导的 IFN-γ 的产生。ODN 1585 可以诱导小鼠已建立的黑色素瘤消退,对小鼠的疟疾也表现出完全的保护作用。ODN 1585 能够用于研究急性骨髓性白血病 (AML) 和疟疾。
T74052 Polyinosinic-polycytidylic acid potassium

Others Others
Polyinosinic-polycytidylic acid potassium (Poly(I:C) potassium) 是双链 RNA 的合成类似物,是一种TLR3和视黄酸诱导型基因 I 受体 (RIG-I 和MDA5) 的激动剂。Polyinosinic-polycytidylic acid potassium 可以用作疫苗佐剂,以增强先天性和适应性免疫反应,并改变肿瘤的微环境,还可以直接触发癌细胞发生凋亡 (Apoptosis)。
T75102 COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)

Others Others
COVID-19 Spike Protein mRNA 用于表达新型冠状病毒肺炎刺突蛋白,关键于 RNA 传递、翻译效率与细胞活力的检测。该蛋白定位于病毒膜表面,主导病毒与宿主细胞膜受体的结合及膜融合,促使 COVID-19 病毒入侵细胞。同时,它是宿主中和抗体作用的主要位点与疫苗开发的核心靶标。
T75116 COVID-19 Spike Protein mRNA-LNP

Others Others
COVID-19 Spike Protein mRNA-LNP 是一种RNA传递系统,利用脂质纳米粒(LNP)封装COVID-19 Spike Protein mRNA,提高翻译效率与细胞活性。COVID-19 Spike Protein,位于新冠病毒膜表面,负责与宿主细胞受体结合和膜融合,是病毒进入细胞的关键因素,同时也是疫苗设计与宿主中和抗体生成的核心靶点。
T74067 Poly (I:C):Kanamycin (1:1) (sodium)

Others Others
Poly (I:C):Kanamycin (1:1) sodium 是 Poly (I:C) 和 Kanamycin 的等比例复合物。Poly(I:C) sodium 是双链 RNA 的合成类似物,是一种TLR3和视黄酸诱导型基因 I 受体 (RIG-I 和MDA5) 的激动剂。Poly(I:C) sodium 可以用作疫苗佐剂,增强先天性和适应性免疫反应,并诱导癌细胞凋亡。Kanamycin 是一种具有口服活性的抗菌剂(革兰氏阴性/阳性细菌),可抑制易位并通过与 70 S 核糖体亚基结合引起错误编码。Kanamycin 对结核分枝杆菌(敏感和耐药)和肺炎克雷伯菌均表现出良好的抑制活性,可用于结核病和肺炎的研究。

化合物

Nelipepimut-S
Cat.No: T33626
Synonym: NeuVax vaccine,E75 peptide,NeuVax
Target:
ALC-0159
Cat.No: T9520
Synonym:
Target: Others
Phenoxyethanol
Cat.No: T20293
Synonym: NSC 1864,乙二醇苯醚,NSC-1864,NSC1864
Target: Others, Antibacterial
RS 09
Cat.No: TP1938
Synonym:
Target: TLR
Vaxfectin
Cat.No: T74240
Synonym:
Target: Liposome
KIN1148
Cat.No: T4027
Synonym:
Target: Influenza Virus
BBIQ
Cat.No: T14513
Synonym:
Target: TLR
NITD-2
Cat.No: T8886
Synonym:
Target: DNA/RNA Synthesis
ALC-0315
Cat.No: T9277
Synonym:
Target: Others
DC-Chol hydrochloride
Cat.No: T35941
Synonym: ​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,​Cholesteryl 3β-N-(dimethylaminoethyl)carbamate
Target: Beta Amyloid
ZINC77292789
Cat.No: TP1166
Synonym: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
Target: Others
Trehalose 6-behenate
Cat.No: T19590
Synonym:
Target: Others
Elpamotide
Cat.No: TP2380
Synonym:
Target:
Onilcamotide
Cat.No: T38550
Synonym:
Target:
STh
Cat.No: T38567
Synonym:
Target:
CoPoP
Cat.No: T84676
Synonym: Cobalt Porphyrin-Phospholipid
Target: Others
M2e, human
Cat.No: T19410
Synonym:
Target: Others
Enterotoxin STp (E. coli)
Cat.No: T82462
Synonym:
Target:
NPNA hexamer
Cat.No: T81645
Synonym:
Target:
Genevant CL1
Cat.No: T75270
Synonym:
Target: Others
GSK1795091
Cat.No: T38619
Synonym: CRX-601
Target: Others
ST101036
Cat.No: T72016
Synonym:
Target: Others
Autoinducing Peptide I
Cat.No: T82930
Synonym:
Target:
Monophosphoryl lipid A
Cat.No: T38636
Synonym: Glucopyranosyl lipid A
Target: Others
KRAS G13D peptide, 25 mer
Cat.No: T38936
Synonym: KRAS G13D peptide, 25 mer
Target:
G0-C14
Cat.No: T75027
Synonym:
Target: Others
AADvac 1
Cat.No: T83224
Synonym:
Target:
IRGRILHDGAYSLTLQGLGIH
Cat.No: T82048
Synonym:
Target:
SPPHPSPAFSPAFDNLYYWDQ
Cat.No: T81112
Synonym:
Target:
SPPHPSPAFSPAFDNLYYWDQ TFA
Cat.No: T81111
Synonym:
Target:
STING agonist-20
Cat.No: T72688
Synonym:
Target: Others
ODN M362
Cat.No: T74916
Synonym:
Target: Others
ODN 1018
Cat.No: T74902
Synonym:
Target: Others
ODN 2395
Cat.No: T74909
Synonym:
Target: Others
16:0 EPC chloride
Cat.No: T74315
Synonym:
Target: Others
ODN 1668
Cat.No: T74903
Synonym:
Target: Others
ODN 24888
Cat.No: T74910
Synonym:
Target: Others
ODN 2336
Cat.No: T74908
Synonym:
Target: Others
ODN 2007
Cat.No: T74905
Synonym:
Target: Others
Propiolactone
Cat.No: T81388
Synonym: Betaprone,β-propiolactone,2-Oxetanone
Target: SARS-CoV
Cholicamideβ
Cat.No: T79707
Synonym:
Target: Necroptosis
M2e, human TFA
Cat.No: T76016
Synonym:
Target:
αGalCer-RBD
Cat.No: T74326
Synonym:
Target: Others
ODN 1585
Cat.No: T64277
Synonym:
Target: Others
Polyinosinic-polycytidylic acid potassium
Cat.No: T74052
Synonym:
Target: Others
COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
Cat.No: T75102
Synonym:
Target: Others
COVID-19 Spike Protein mRNA-LNP
Cat.No: T75116
Synonym:
Target: Others
Poly (I:C):Kanamycin (1:1) (sodium)
Cat.No: T74067
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN2232 Soyasaponin Ab

NOS; NF-κB; COX Immunology/Inflammation; Neuroscience; NF-κB
Soyasaponin Ab 是一种大豆皂苷。Soyasaponin Ab 在 3T3-L1 脂肪细胞中通过下调 PPARγ 产生抗肥胖的作用。
TN2230 Soyasaponin Ba

大豆皂苷 BA,大豆皂苷Ba

Others Others
Soyasaponin Ba 是一种大豆皂苷,分离自菜豆类,可用作醛糖还原酶抑制剂。
TN4804 Platycoside A

Antifection Microbiology/Virology
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice.
T38838 QS-21

Stimulon,QS-21

Others Others
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.
T37272 9(S),12(S),13(S)-TriHOME

Others Others
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...

天然产物

Soyasaponin Ab
Cat.No: TN2232
Synonym:
Target: NOS, NF-κB, COX
Soyasaponin Ba
Cat.No: TN2230
Synonym: 大豆皂苷 BA,大豆皂苷Ba
Target: Others
Platycoside A
Cat.No: TN4804
Synonym:
Target: Antifection
QS-21
Cat.No: T38838
Synonym: Stimulon,QS-21
Target: Others
9(S),12(S),13(S)-TriHOME
Cat.No: T37272
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00261 Bovine coronavirus (strain vaccine) Spike glycoprotein (His)

Spike glycoprotein,E2,S glycoprotein,S,Peplomer protein

BCoV E. coli
Bovine coronavirus (strain vaccine) Spike glycoprotein (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 24.6 kDa and the accession number is P25194.
TMPH-02983 Mumps virus (strain Miyahara vaccine) Hemagglutinin-neuraminidase Protein (His)

HN,Hemagglutinin-neuraminidase

MuV E. coli
Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.; Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins. Mumps virus (strain Miyahara vaccine) Hemagglutinin-neuraminidase Protein (His) is expressed in E. coli expression sy...
TMPK-01192 Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)

Envelope glycoprotein E,ORF68,gE

Varicella-zoster virus (strain Oka vaccine) HEK293 Cells
VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antibodies and T cell responses that is often selected as vaccine candidate antigen.
TMPY-06867 Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein

VZV CHO Cells
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein is expressed in CHO mammalian cells. The predicted molecular weight is 85.17 kDa.
TMPY-06855 Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein

VZV CHO Cells
Varicella-zoster virus (VZV) is a highly fusogenic virus, but the degree of fusion is dependent on the cell substrate in which the virus is propagated. Varicella-zoster virus (VZV) is classified as an alphaherpesvirus based on its growth characteristics and its ability to become latent in the nervous system of the host. Like all known herpesviruses, VZV encodes a homolog of glycoprotein B (gB). Glycoprotein B (gB) is the most conserved entry glycoprotein among herpesviruses with an amino acid se...
TMPH-03427 Rubella virus (strain RA27/3 vaccine) Structural polyprotein (His)

p110,Structural polyprotein

RUBV Baculovirus Insect Cells
Rubella virus (strain RA27/3 vaccine) Structural polyprotein (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 53.4 kDa and the accession number is P19725.
TMPH-02453 Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)

N,Nucleoprotein,Nucleocapsid protein

MeV Baculovirus Insect Cells
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B8PZP3.
TMPH-03683 Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)

Envelope glycoprotein H,gH

HHV-3 E. coli
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) is expressed in E...
TMPH-02454 Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His)

Nucleoprotein,N,Nucleocapsid protein

MeV E. coli
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is B8PZP3.
TMPH-03685 Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)

Envelope glycoprotein L,gL

HHV-3 E. coli
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The...
TMPY-01813 ACRV1 Protein, Human, Recombinant (His)

SP-10,SPACA2,D11S4365,acrosomal vesicle protein 1

Human HEK293 Cells
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr...
TMPK-01473 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402,HLA-A*24:02,Melanoma-assoc...

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01493 HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)

MZ2-D,Melanoma-associated antigen 3,MAGE-3,CT1.3,MZ2D

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01040 NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)

NKG2C,NK cell receptor C,CD159c,KLRC2

Cynomolgus HEK293 Cells
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness.
TMPK-01474 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01472 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)

MAGE-3,CT1.3,Melanoma-associated antigen 3,MZ2D,MZ2-D,HLA-A*...

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01495 HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)

Melanoma-associated antigen 3,CT1.3,MZ2D,MAGE-3,MZ2-D

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPY-05693 SARS-CoV-2 Methyltransferase/ME Protein (His)

SARS-CoV-2 E. coli
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate immunity during viral infection. Nonstructural protein 16 (NSP16) / viral 2'O-methyltransferase (2'O-MTase) is highly conserved. The conserved 2'O-MTase activity is important for CoV pathogenesis and NSP16 is a conserved universal target for rapid live attenuated vaccine design ...
TMPK-00436 SARS-COV-2 Spike S1 Protein (D614G, His & Avi)

Spike,S1 protein,Spike protein S1,S glycoprotein Subunit1,S1...

SARS-CoV-2 HEK293 Cells
The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. Here, we analyze the D614G mutation in the context of a soluble S ectodomain construct.
TMPK-01199 NKG2C/CD159c Protein, Mouse, Recombinant (hFc)

NKG2C,KLRC2,CD159c,NK cell receptor C

Mouse HEK293 Cells
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted m...
TMPK-00859 NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated

NK cell receptor C,KLRC2,CD159c,NKG2C

Human HEK293 Cells
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-...
TMPK-00858 NKG2C/CD159c Protein, Human, Recombinant (His & Avi)

NK cell receptor C,KLRC2,CD159c,NKG2C

Human HEK293 Cells
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness. NKG2C/CD159c Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The p...
TMPY-00248 Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

Lymphotoxin β,lymphotoxin β (TNF superfamily, member 3),lymp...

Cynomolgus Baculovirus Insect Cells
LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in seve...
TMPY-01775 AIM2 Protein, Human, Recombinant (GST)

absent in melanoma 2,PYHIN4

Human Baculovirus Insect Cells
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytoplasmic DNA by means of its oligonucleotide/oligosaccharide-binding domain and interacts with ASC (apoptosis-associated speck-like protein containing a CARD) through its pyrin domain to activate caspase-1. In response to foreign cytoplasmic DNA, AIM2 forms an inflammasome, resulting...
TMPY-06885 SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...

重组蛋白

Bovine coronavirus (strain vaccine) Spike glycoprotein (His)
Cat.No: TMPH-00261
Species: BCoV
Expression System: E. coli
Mumps virus (strain Miyahara vaccine) Hemagglutinin-neuraminidase Protein (His)
Cat.No: TMPH-02983
Species: MuV
Expression System: E. coli
Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)
Cat.No: TMPK-01192
Species: Varicella-zoster virus (strain Oka vaccine)
Expression System: HEK293 Cells
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein
Cat.No: TMPY-06867
Species: VZV
Expression System: CHO Cells
Varicella-zoster virus (VZV) (strain Oka vaccine) Glycoprotein B/gB Protein
Cat.No: TMPY-06855
Species: VZV
Expression System: CHO Cells
Rubella virus (strain RA27/3 vaccine) Structural polyprotein (His)
Cat.No: TMPH-03427
Species: RUBV
Expression System: Baculovirus Insect Cells
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)
Cat.No: TMPH-02453
Species: MeV
Expression System: Baculovirus Insect Cells
Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His)
Cat.No: TMPH-03683
Species: HHV-3
Expression System: E. coli
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His)
Cat.No: TMPH-02454
Species: MeV
Expression System: E. coli
Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)
Cat.No: TMPH-03685
Species: HHV-3
Expression System: E. coli
ACRV1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01813
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01473
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01493
Species: Human
Expression System: HEK293 Cells
NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01040
Species: Cynomolgus
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01474
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01472
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01495
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Methyltransferase/ME Protein (His)
Cat.No: TMPY-05693
Species: SARS-CoV-2
Expression System: E. coli
SARS-COV-2 Spike S1 Protein (D614G, His & Avi)
Cat.No: TMPK-00436
Species: SARS-CoV-2
Expression System: HEK293 Cells
NKG2C/CD159c Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01199
Species: Mouse
Expression System: HEK293 Cells
NKG2C/CD159c Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00859
Species: Human
Expression System: HEK293 Cells
NKG2C/CD159c Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00858
Species: Human
Expression System: HEK293 Cells
Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00248
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
AIM2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01775
Species: Human
Expression System: Baculovirus Insect Cells
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
Cat.No: TMPY-06885
Species:
Expression System:
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