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134

抑制剂 & 化合物

18

天然产物

49

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3

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T39009 CAP18 (rabbit)

CAP18 (rabbit)

CAP18 (rabbit) is a 37 amino acid antimicrobial peptide derived from rabbit granulocytes. It exhibits extensive antimicrobial activity against both Gram-positive (IC50, 130-200 nM) and Gram-negative (IC50, 20-100 nM) bacteria. Thus, CAP18 (rabbit) holds promise for the study and advancement of bacterial sepsis research.
TP1175 Endothelin-3, human, mouse, rabbit, rat

Endothelin 3 (Rat,Human)

Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
TP1173 Endothelin 3 (Rat,Human) (TFA)

Endothelin-3, human, mouse, rabbit, rat TFA

Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that specifically interacts with G-protein-linked transmembrane receptors, ET-RA and ET-RB.
T34862 Thromboxane A2

Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2

Others Others
Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction.
T16420 P-1075

Potassium Channel Membrane transporter/Ion channel
P-1075 是磺酰脲受体2相关的 ATP 敏感性的钾通道(SUR2-KIR6)的激活剂,EC50为 45 nM。它在兔子中通过打开线粒体 K (ATP) 通道产生活性氧,产生保护心脏的功效。
TP1016 Aviptadil

Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine),阿肽地尔

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.
T81316 Rabbit neutrophil peptide 3b

Rabbit Neutrophil Peptide 3b,一种源自兔腹膜中性粒细胞的抗菌肽。
T81317 Rabbit IgG1 kappa, Isotype Control

RabbitIgG1kappa, Isotype Control为兔源IgG1κ同型对照单克隆抗体,用于科研中作为Rabbit IgG1κ抗体的实验对照。
T1736 Apixaban

阿哌沙班,BMS-562247-01

Factor Xa Metabolism
Apixaban (BMS-562247-01) 是一种高度选择性,可逆的、口服具有活力的凝血因子 Xa (Factor Xa) 抑制剂,抑制人和兔凝血因子 Xa 的 Ki 分别为 0.08 nM 和 0.17 nM。它可以用于研究各种血栓栓塞疾病。
T7530 PD146176

NSC168807

Ferroptosis; Lipoxygenase; Autophagy Apoptosis; Autophagy; Metabolism
PD146176 (NSC-168807) 是一种 15-脂氧合酶(15-LO)抑制剂,抑制兔网织红细胞 15-LO,Ki 为 197 nM,IC50 为 0.54 μM。 它通过刺激老年三重转基因小鼠的自噬来逆转认知障碍、脑淀粉样变性和 tau 病理学。
T76500 ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)

ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) 是ACTH的3-24片段,适用于癌症、免疫疾病、心血管疾病等多种疾病的研究。
T64587 p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R

Others Others
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64587。
T64611 Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R

Others Others
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64611。
T81591 Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)

Human PTHrP(107-111) amide

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) 是一段具有抑制骨吸收作用的C端甲状旁腺激素相关蛋白片段。
T64608 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R

Others Others
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64608。
TP1016L Aviptadil Acetate

醋酸阿肽地尔,阿肽地尔,Vasoactive Intestinal Peptide acetate salt

RAAS; SARS-CoV Endocrinology/Hormones; Microbiology/Virology
Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) 是模拟血管活性肠多肽类似物,具有血管舒张效应。它可诱导肺血管舒张并抑制血管 SMC 的增殖和血小板聚集。它可用于研究 SARS-CoV-2 引起的肺纤维化、肺动脉高压和呼吸衰竭。
T17196 UC-1728

t-TUCB

Epoxide Hydrolase Metabolism
UC-1728 (t-TUCB) 是一种兔子可溶性环氧化物水解酶抑制剂,兔子肝脏中测得其IC50=2 nM。
T13373 YM17E

Acyltransferase; AChR Metabolism; Neuroscience
YM17E 是一种 ACAT 抑制剂,在体外兔肝微粒体中的 IC50 为 44 nM。
T3757 NQ301

Thrombin; Platelet aggregation Others; Proteases/Proteasome
NQ301 是一种抗血栓剂,能够抑制胶原蛋白激发的兔血小板聚集,IC50=10 mg/mL。
T16411 Otenzepad

AF-DX 116

AChR Neuroscience
Otenzepad (AF-DX 116) 是 M2 mAChR 的特异性拮抗剂,对大鼠心脏和兔外周肺的 IC50 分别为 386 nM 和 640 nM。
T12767 RP 70676

Acyltransferase Metabolism
RP 70676 是ACAT 抑制剂,抑制大鼠和兔子中 ACAT 的IC50分别为 25 和 44 nM。
T67805 Oxepinac

Others Others
oxepinac 是一种治疗疼痛性骨关节炎的有效且耐受性良好的化合物。oxepinac 在动物实验中对小鼠和家兔胎儿无致畸作用。
TQ0038 Brensocatib

AZD7986,INS 1007

Proteasome Proteases/Proteasome; Ubiquitination
Brensocatib (AZD7986) 是一种二肽基肽酶 1 (DPP1) 抑制剂,在人,小鼠,大鼠,狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。
TP1917L1 Sar-[D-Phe8]-des-Arg9-Bradykinin acetate

Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base)

Bradykinin Receptor GPCR/G Protein
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) 是一种有效的选择性缓激肽 B1 受体激动剂(兔主动脉中的 EC50 = 9.02 nM),对氨肽酶、激肽酶 I 和 II (ACE) 以及中性内肽酶切割具有抗性。在体内表现出降血压和血管生成活性。
T22964 Glemanserin

MDL11939

5-HT Receptor GPCR/G Protein; Neuroscience
Glemanserin (MDL11939) 是一种特异性 5-HT2A 拮抗剂,对兔、人和大鼠 5-HT2A 的 Ki 值为 0.54 nM、2.5 nM 和 2.89 nM。
T15338 Foropafant

SR27417,福罗帕泛

Others; Platelet aggregation Others
Foropafant (SR27417) 是一种高效和特异性的血小板活化因子 (PAF) 受体拮抗剂 (Ki: 57 pM)。 Foropafant 有效抑制 PAF 诱导的兔和人血小板聚集。
T31597 Ecabapide

DQ2511,DQ 2511,DQ-2511

Others Others
Ecabapide (DQ-2511) 是一种新型促胃肠蠕动剂,能显著增强SHRSP的胃排空能力。Ecabapide 可激活的兔胃壁细胞中的环状 GMP 依赖性管家 Cl- 通道。
T14506 BAY 60-6583

Others; Adenosine Receptor GPCR/G Protein; Neuroscience; Others
BAY 60-6583 是一种强效、高亲和力的腺苷 A2B 受体激动剂(EC50 = 3 nM),对A2B 受体的亲和力超过对 A1、A2A 和 A3 受体的亲和力。BAY 60-6583 在心肌缺血模型中具有心脏保护作用。BAY 60-6583 与小鼠、兔子和狗 A2BAR 的结合 Ki 值分别为 750 nM、340 nM 和 330 nM。
T25102 Aprikalim

RP-52891,RP 52891,RP52891

Potassium Channel Membrane transporter/Ion channel
Aprikalim (RP 52891) 是一种三磷酸腺苷钾通道(KATP)开启剂,可保护脊髓缺血兔模型中的神经受到损伤。Aprikalim 抑制血管收缩,抑制心肌麻痹期间 [Ca2+]i 升高,可以用于研究心血管疾病。
T9901A-008 Volociximab

Eos 200-4,M200

Integrin Cytoskeletal Signaling
Volociximab (M200) 是一种靶向 α5β1 整合素的 IgG4 单克隆抗体 ,具有抗血管生成、抗肿瘤和抗癌活性,可抑制兔子 VX2 肿瘤的生长,用于研究实体瘤。
T16865 SCH28080

ATPase; Proton pump Membrane transporter/Ion channel
SCH28080 是一种可逆且具有 K+ 竞争性的胃 H+/K+-ATP 酶 (H+/K+-ATPase) 抑制剂,IC50 值为 20 nM (家兔微粒体膜)。SCH28080 在体内是有效的酸分泌抑制剂,具有抗溃疡活性、抗分泌和细胞保护活性。
T6236 Ozagrel

奥扎格雷,OKY-046,Domenan

Thrombin; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
Ozagrel (Domenan) 是血栓烷 A2(TXA2) 合酶抑制剂,可抑制哮喘。它也是一种抗血小板剂,可选择性抑制人血小板聚集,IC50为 53.12 μM。
T30249 AZD 7009

AZD-7009,AZD7009

Sodium Channel Membrane transporter/Ion channel
AZD 7009是一种新型抗心律失常化合物,对CHO K1细胞中 hNav1.5的钠电流具有抑制作用,IC50为11 uM。AZD 7009 对离体兔心房和心室肌细胞的晚期钠电流具有抑制作用,对e -4031诱导的动作电位持续时间延长具有抑制作用,促使浦肯野纤维的早期后去极化(EADs)。
T11918L Lysipressin acetate(50-57-7(fb_acetate))

Lysine vasopressin acetate,[Lys8]-Vasopressin acetate

Others Others
Lysipressin acetate(50-57-7(fb_acetate)) ([Lys8]-Vasopressin acetate) 诱导兔膀胱平滑肌收缩,激活腺苷酸环化酶。 Lysipressin 是一种抗利尿激素,已在猪和一些有袋动物家族中发现。
T22530 6-Chloromelatonin

Melatonin Receptor; Dopamine Receptor GPCR/G Protein; Neuroscience
6-Chloromelatonin 是一种有效的褪黑素受体 (melatonin receptor) 激动剂,是一种5-甲氧基吲哚化合物,可竞争兔视网膜中相同的突触前褪黑激素受体位点 ,可抑制[3H]多巴胺的钙依赖性释放 具有比褪黑素更高的代谢稳定性。6-Chloromelatonin 竞争 [3H] 褪黑素 与 MT2 受体结合 (pKi=9.77),可能用于研究与抑郁症相关的失眠和睡眠障碍。
T21871 MMPSI

Caspase-3/7 Inhibitor I

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
MMPSI (Caspase-3/7 Inhibitor I) 是一种新型的、非肽类的小分子 caspase 3 和 caspase 7 抑制剂,可减少离体兔心脏或心肌细胞缺血性损伤的作用,以浓度依赖性方式抑制 H16c2 细胞凋亡 。MMPSI 可用于研究心脏保护和心肌损伤。
T35841 5-Benzyloxygramine

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂,具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体,可拮抗 5-HT 对大鼠子宫和兔耳的作用。
T16240 N,N'-Diacetyl-L-cystine

(Ac-Cys-OH)2,DiNAC

Others Others
N,N'-Diacetyl-L-cystine (DiNAC) 是一种具有免疫调节特性的 N-乙酰基半胱氨酸的二硫二聚体。它在高脂血症兔中也具有抗动脉粥样硬化的作用。它是啮齿类动物中接触敏感/迟发型超敏反应的有效口服活性调节剂。
TP1937L1 RFRP-1 (human) acetate(311309-25-8 free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
RFRP-1 (human) acetate(311309-25-8 free base) 是一种有效的内源性 NPFF 受体激动剂(NPFF2 和 NPFF1 的 EC50 值分别为 0.0011 和 29 nM)。它减弱离体大鼠和兔心肌细胞的收缩功能。降低心率、每搏输出量、射血分数和心输出量,并增加大鼠的血浆催乳素水平。 GnIH 同系物。
T10421 AVE5688

Phosphorylase Metabolism
AVE5688 是糖原磷酸化酶 (glycogen phosphorylase (GP)) 抑制剂,抑制兔肌肉糖原磷酸化酶 rmGPb 和 rmGPa 的活性,IC50 值分别为 430 nM 和 915 nM,Kd 值分别为 170 nM 和 530 nM;AVE5688 可用于二型糖尿病的研究。
T24906L Tuna AI acetate

Angiotensin-converting Enzyme (ACE) Metabolism
Tuna AI acetate 是一种源自金枪鱼肌肉的非竞争性血管紧张素转换酶 (ACE) 抑制剂。
T6035 Odanacatib

奥达卡替,奥当卡替,MK-0822

Cysteine Protease Proteases/Proteasome
Odanacatib 是组织蛋白酶K(人/兔)的选择性抑制剂,IC50分别为0.2 nM 和 1 nM。
T13369 YM-264

Others Others
YM-264 is a selective and orally active antagonist of platelet-activating factor (PAF) (pKi value of 8.85 for rabbit platelet membranes).
T13160 Timegadine

替美加定,SR1368

COX Immunology/Inflammation; Neuroscience
Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates and in washed rabbit platelets.
T39223 Milvexian

JNJ-70033093,BMS-986177

Others Others
Milvexian (BMS-986177) is a potent antithrombotic compound that inhibits human and rabbit factor XIa (FXIa) directly and reversibly. It is orally-bioavailable and exhibits a K i of 0.11 nM and 0.38 nM against human and rabbit FXIa, respectively.
T20697 Robenidine

Chimcoccide,Khimcoccid

Others Others
Robenidine, an anticoccidial guanidine, is used as an additive in rabbit fodder.
T27574 ZM 169369

ICI169369,ICI-169369

Others Others
ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.
T37210 5-hydroxy Indomethacin

Others Others
5-hydroxy Indomethacin is a metabolite of indomethacin .1It is formed from indomethacin in rabbit hepatic microsomes. 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism in isolated neonatal and fetal rabbit hepatocytesPediatr. Res.15(11)1406-1410(1981)
T13129 Terodiline hydrochloride

AChR Neuroscience
Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively).
T26621 AMP-579

RPR100579,RPR 100579,AMP 579,RPR-100579

Others Others
AMP-579 is an adenosine A1 receptor agonist. AMP-579 also acts as a A2b-adenosine receptor agonist in human 293 cells and rabbit hearts.

化合物

CAP18 (rabbit)
Cat.No: T39009
Synonym: CAP18 (rabbit)
Target:
Endothelin-3, human, mouse, rabbit, rat
Cat.No: TP1175
Synonym: Endothelin 3 (Rat,Human)
Target:
Endothelin 3 (Rat,Human) (TFA)
Cat.No: TP1173
Synonym: Endothelin-3, human, mouse, rabbit, rat TFA
Target:
Thromboxane A2
Cat.No: T34862
Synonym: Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2
Target: Others
P-1075
Cat.No: T16420
Synonym:
Target: Potassium Channel
Aviptadil
Cat.No: TP1016
Synonym: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine),阿肽地尔
Target:
Rabbit neutrophil peptide 3b
Cat.No: T81316
Synonym:
Target:
Rabbit IgG1 kappa, Isotype Control
Cat.No: T81317
Synonym:
Target:
Apixaban
Cat.No: T1736
Synonym: 阿哌沙班,BMS-562247-01
Target: Factor Xa
PD146176
Cat.No: T7530
Synonym: NSC168807
Target: Ferroptosis, Lipoxygenase, Autophagy
ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)
Cat.No: T76500
Synonym:
Target:
p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R
Cat.No: T64587
Synonym:
Target: Others
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R
Cat.No: T64611
Synonym:
Target: Others
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
Cat.No: T81591
Synonym: Human PTHrP(107-111) amide
Target:
Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R
Cat.No: T64608
Synonym:
Target: Others
Aviptadil Acetate
Cat.No: TP1016L
Synonym: 醋酸阿肽地尔,阿肽地尔,Vasoactive Intestinal Peptide acetate salt
Target: RAAS, SARS-CoV
UC-1728
Cat.No: T17196
Synonym: t-TUCB
Target: Epoxide Hydrolase
YM17E
Cat.No: T13373
Synonym:
Target: Acyltransferase, AChR
NQ301
Cat.No: T3757
Synonym:
Target: Thrombin, Platelet aggregation
Otenzepad
Cat.No: T16411
Synonym: AF-DX 116
Target: AChR
RP 70676
Cat.No: T12767
Synonym:
Target: Acyltransferase
Oxepinac
Cat.No: T67805
Synonym:
Target: Others
Brensocatib
Cat.No: TQ0038
Synonym: AZD7986,INS 1007
Target: Proteasome
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate
Cat.No: TP1917L1
Synonym: Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base)
Target: Bradykinin Receptor
Glemanserin
Cat.No: T22964
Synonym: MDL11939
Target: 5-HT Receptor
Foropafant
Cat.No: T15338
Synonym: SR27417,福罗帕泛
Target: Others, Platelet aggregation
Ecabapide
Cat.No: T31597
Synonym: DQ2511,DQ 2511,DQ-2511
Target: Others
BAY 60-6583
Cat.No: T14506
Synonym:
Target: Others, Adenosine Receptor
Aprikalim
Cat.No: T25102
Synonym: RP-52891,RP 52891,RP52891
Target: Potassium Channel
Volociximab
Cat.No: T9901A-008
Synonym: Eos 200-4,M200
Target: Integrin
SCH28080
Cat.No: T16865
Synonym:
Target: ATPase, Proton pump
Ozagrel
Cat.No: T6236
Synonym: 奥扎格雷,OKY-046,Domenan
Target: Thrombin, Prostaglandin Receptor
AZD 7009
Cat.No: T30249
Synonym: AZD-7009,AZD7009
Target: Sodium Channel
Lysipressin acetate(50-57-7(fb_acetate))
Cat.No: T11918L
Synonym: Lysine vasopressin acetate,[Lys8]-Vasopressin acetate
Target: Others
6-Chloromelatonin
Cat.No: T22530
Synonym:
Target: Melatonin Receptor, Dopamine Receptor
MMPSI
Cat.No: T21871
Synonym: Caspase-3/7 Inhibitor I
Target: Apoptosis, Caspase
5-Benzyloxygramine
Cat.No: T35841
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
N,N'-Diacetyl-L-cystine
Cat.No: T16240
Synonym: (Ac-Cys-OH)2,DiNAC
Target: Others
RFRP-1 (human) acetate(311309-25-8 free base)
Cat.No: TP1937L1
Synonym:
Target: Neuropeptide Y Receptor
AVE5688
Cat.No: T10421
Synonym:
Target: Phosphorylase
Tuna AI acetate
Cat.No: T24906L
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Odanacatib
Cat.No: T6035
Synonym: 奥达卡替,奥当卡替,MK-0822
Target: Cysteine Protease
YM-264
Cat.No: T13369
Synonym:
Target: Others
Timegadine
Cat.No: T13160
Synonym: 替美加定,SR1368
Target: COX
Milvexian
Cat.No: T39223
Synonym: JNJ-70033093,BMS-986177
Target: Others
Robenidine
Cat.No: T20697
Synonym: Chimcoccide,Khimcoccid
Target: Others
ZM 169369
Cat.No: T27574
Synonym: ICI169369,ICI-169369
Target: Others
5-hydroxy Indomethacin
Cat.No: T37210
Synonym:
Target: Others
Terodiline hydrochloride
Cat.No: T13129
Synonym:
Target: AChR
AMP-579
Cat.No: T26621
Synonym: RPR100579,RPR 100579,AMP 579,RPR-100579
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4850 PCL 016

2-吡啶甲酸,2-Picolinic acid

Virus Protease; Endogenous Metabolite Metabolism; Microbiology/Virology
PCL 016 (2-Picolinic acid) 是一种局部抗病毒剂,可抑制兔体内的腺病毒复制。
TN1528 Cotoin

AChE Neuroscience
Cotoin 是从 Garcinia virgate 茎皮中分离出的一种天然产物。Cotoin 具有解痉活性,可降低孤立的兔肠的音调和收缩。它部分抑制乙酰胆碱、毛果芸香碱和 BaCl 对分离肠的影响。
T7030 anemarsaponin B

知母皂苷B,知母皂苷 B

p38 MAPK; NF-κB; MEK; COX; NO Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Anemarsaponin B 是一种甾体皂苷,可降低iNOS 和COX-2的蛋白和 mRNA 水平,减少促炎细胞因子的表达和产生。它通过阻断 IκBα 的磷酸化来抑制NF-κB 的 p65 亚基的核转位,还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 的磷酸化。
T3S1967 (S)-Indoximod

N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine

Others; Indoleamine 2,3-Dioxygenase (IDO) Metabolism; Others
(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,可用于研究癌症。
T6S0033 Crotonoside

巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE

Others; FLT; HDAC Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others; Tyrosine Kinase/Adaptors
Crotonoside (Isoguanosine) 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。
TN6575 Pilosidine

Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
T27436 GS 389

GS-389,GS389

Others Others
GS 389 is a novel tetrahydroisoquinoline analog with vasorelaxant properties. GS-389 significantly inhibited cGMP phosphodiesterase from the rabbit brain and increased cGMP levels in the rat aorta.
TN7543 (S)-Laudanosine

NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine

Others Others
(S)-Laudanosine, the (S) enantiomer of laudanosine, emerges as a metabolite from the neuromuscular blocking agents atracurium and cisatracurium. It functions by inhibiting prolyl endopeptidase and obstructing arachidonic acid- and collagen-induced aggregation in washed rabbit platelets.
T10913 Cyclobuxine D

Others Others
Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclostatin D has obvious bradycardia effect on rat heart, and inhibits acetylcholine and Ba ++ induced longitudinal muscle contraction isolated from rabbit jejunum.
TN1980 Neocryptotanshinone

Others Others
Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid.
TN4794 Pinusolidic acid

PAFR GPCR/G Protein
Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 micrograms/ml).
T75570 Justicidin C

Others Others
Justicidin C 是一种抗病毒木脂素,对水泡性口炎病毒展现了较强的抗病毒活性,同时在兔肺细胞(RL-33)中显示较低的细胞毒性。
T79950 Piperulin A

Others Others
Piperulin A,作为一种有效的PAFR抑制剂,其通过抑制兔血小板质膜上PAFR的特异性结合,展现出其功能,IC50值为7.3 μM。
TN3568 Calceolarioside A

Calcium Channel; Antifection Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly related to a calcium-dependent mechanism. Calceolarioside A also has potent antioxidative activi
T83460 11-O-β-D-glucopyranosyl thamnosmonin

11-O-β-D-glucopyranosyl thamnosmonin是一种香豆素苷,能够从Angelica apaensis根部提取。该化合物对PAF、AA和ADP诱发的兔血小板聚集表现出轻度的抑制效果。
TN4937 Sambutoxin

Others Others
Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers, it can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, and, finally, death when rats were
T38330 Collinin

Others Others
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
T83915 Norbixin hydrate

Others Others
Norbixin是一种在B. orellana中发现的类胡萝卜素,具有多样的生物活性。在无细胞测试中,它与过氧化物酶体增殖物激活受体γ (PPARγ)结合(Ki = 1.15 µM)。在心脑血管代谢综合征大鼠模型中,Norbixin (47.7 mg/kg) 能够减轻高血糖、高胰岛素血症和胰岛素抗性,降低血清脂质水平及心脏中硫代巴比妥酸反应性物质(TBARS)和谷胱甘肽(GSH)的水平。在胆固醇诱导的动脉粥样硬化兔模型中,它降低氧化型LDL和主动脉蛋白氧化水平,并减少动脉粥样硬化面积。Norbixin(每天0.1和1 mg/kg)减少汞诱导的大鼠肝细胞和白细胞DNA损伤。此外,它还能预防与年龄相关的黄斑变性(AMD)Abca4-/- Rdh8-/-小鼠模型中的光感受器退化。

天然产物

PCL 016
Cat.No: T4850
Synonym: 2-吡啶甲酸,2-Picolinic acid
Target: Virus Protease, Endogenous Metabolite
Cotoin
Cat.No: TN1528
Synonym:
Target: AChE
anemarsaponin B
Cat.No: T7030
Synonym: 知母皂苷B,知母皂苷 B
Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase
(S)-Indoximod
Cat.No: T3S1967
Synonym: N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine
Target: Others, Indoleamine 2,3-Dioxygenase (IDO)
Crotonoside
Cat.No: T6S0033
Synonym: 巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE
Target: Others, FLT, HDAC
Pilosidine
Cat.No: TN6575
Synonym:
Target:
GS 389
Cat.No: T27436
Synonym: GS-389,GS389
Target: Others
(S)-Laudanosine
Cat.No: TN7543
Synonym: NSC 35045,L-(+)-Laudanosine,(+)-Laudanosine,L-Laudanosine
Target: Others
Cyclobuxine D
Cat.No: T10913
Synonym:
Target: Others
Neocryptotanshinone
Cat.No: TN1980
Synonym:
Target: Others
Pinusolidic acid
Cat.No: TN4794
Synonym:
Target: PAFR
Justicidin C
Cat.No: T75570
Synonym:
Target: Others
Piperulin A
Cat.No: T79950
Synonym:
Target: Others
Calceolarioside A
Cat.No: TN3568
Synonym:
Target: Calcium Channel, Antifection
11-O-β-D-glucopyranosyl thamnosmonin
Cat.No: T83460
Synonym:
Target:
Sambutoxin
Cat.No: TN4937
Synonym:
Target: Others
Collinin
Cat.No: T38330
Synonym:
Target: Others
Norbixin hydrate
Cat.No: T83915
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00779 TNF alpha Protein, Rabbit, Recombinant

TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum...

Rabbit E. coli
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ...
TMPY-03634 CD38 Protein, Rabbit, Recombinant (His)

CD38 molecule,ADPRC1

Rabbit HEK293 Cells
CD38 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9MZ03.
TMPH-03202 DAG1 Protein, Rabbit, Recombinant (His)

Dystroglycan 1,Dystroglycan,Dystrophin-associated glycoprote...

Rabbit E. coli
DAG1 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 73.5 kDa and the accession number is Q28685.
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His)

TFPI,Lipoprotein-associated coagulation inhibitor,Extrinsic ...

Rabbit HEK293 Cells
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761.
TMPY-04888 IL-17 Protein, Rabbit, Recombinant

白细胞介素,白介素,interleukin 17A

Rabbit E. coli
IL-17 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is G1SLF2.
TMPY-04663 TrkA Protein, Rabbit, Recombinant (His)

neurotrophic tyrosine kinase, receptor, type 1

Rabbit HEK293 Cells
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is XP_008262512.1.
TMPH-03217 VEGFA Protein, Rabbit, Recombinant (His)

Rabbit P. pastoris (Yeast)
VEGFA Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 51.7 kDa and the accession number is XP_002714743.1.
TMPY-04609 IL-17 Protein, Rabbit, Recombinant (His)

白细胞介素,白介素,interleukin 17A

Rabbit Baculovirus Insect Cells
IL-17 Protein, Rabbit, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is G1SLF2.
TMPJ-00959 B7-2 Protein, Rabbit, Recombinant (His)

CD86,T-lymphocyte activation antigen CD86,Activation B7-2 an...

Rabbit HEK293 Cells
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
TMPH-03212 TPM1 Protein, Rabbit, Recombinant (His & Myc)

TPM1,Alpha-tropomyosin,Tropomyosin alpha-1 chain,Tropomyosin...

Rabbit Baculovirus Insect Cells
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 3...
TMPH-03218 VEGFA Protein, Rabbit, Recombinant (His & SUMO)

Rabbit E. coli
N/A. VEGFA Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.7 kDa and the accession number is XP_002714743.1.
TMPH-03198 MGAT1 Protein, Rabbit, Recombinant (His & Myc)

MGAT1,Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosa...

Rabbit E. coli
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.2 kDa and the accession number is P27115.
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)

Activation B7-1 antigen,T-lymphocyte activation antigen CD80...

Rabbit HEK293 Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPY-04831 NGFR/p75NTR Protein, Rabbit, Recombinant (hFc)

NGFR,nerve growth factor receptor (TNFR superfamily, member ...

Rabbit HEK293 Cells
NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is XP_008269543.1.
TMPY-04792 IL-23 Protein, Rabbit, Recombinant (His)

白介素,白细胞介素

Rabbit HEK293 Cells
IL-23 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.6 kDa and the accession number is XP_002710393.1&XP_002711125.1.
TMPH-03203 FGFb Protein, Rabbit, Recombinant (His & SUMO)

Basic fibroblast growth factor,Fibroblast growth factor 2,FG...

Rabbit E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPY-00259 IL-12B Protein, Rabbit, Recombinant (His)

interleukin 12B

Rabbit HEK293 Cells
IL-12B Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.1 kDa and the accession number is G1TBD7.
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His)

Lipoprotein-associated coagulation inhibitor,Extrinsic pathw...

Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761.
TMPH-03208 IL-6 Protein, Rabbit, Recombinant (His)

Interleukin-6,IL6

Rabbit P. pastoris (Yeast)
IL-6 Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q9MZR1.
TMPH-03207 IL-2 Protein, Rabbit, Recombinant (His)

T-cell growth factor,IL2,Interleukin-2

Rabbit E. coli
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. IL-2 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.1 kDa and the accession number is O77620.
TMPY-05287 CD64A Protein, Rabbit, Recombinant (His)

Rabbit HEK293 Cells
CD64A Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is G1SJM8.
TMPH-03199 APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)

APOE,Apolipoprotein E,Apo-E

Rabbit E. coli
APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P18287.
TMPY-04646 NGFR/p75NTR Protein, Rabbit, Recombinant (His)

神经生长因子,nerve growth factor receptor (TNFR superfamily, membe...

Rabbit HEK293 Cells
NGFR/p75NTR Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is XP_008269543.1.
TMPY-06738 Ory c 3 Protein, Rabbit, Recombinant

Rabbit P. pastoris (Yeast)
Ory c 3 Protein, Rabbit, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 18.3 kDa.
TMPY-02318 Tissue Factor Protein, Rabbit, Recombinant (His)

coagulation factor III (thromboplastin, tissue factor)

Rabbit HEK293 Cells
Tissue Factor Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P24055.
TMPH-03204 GHR Protein, Rabbit, Recombinant (His & Myc)

GHR,Somatotropin receptor,Growth hormone receptor

Rabbit E. coli
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941.
TMPH-03201 CD40 Ligand Protein, Rabbit, Recombinant (His)

TNLG8B,CD40 ligand,CD40-L,CD40LG,Tumor necrosis factor ligan...

Rabbit P. pastoris (Yeast)
N/A. CD40 Ligand Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.2 kDa and the accession number is G1SKP7.
TMPH-03209 CLNS1A Protein, Rabbit, Recombinant (His & Myc)

I(Cln),Chloride conductance regulatory protein ICln,Methylos...

Rabbit E. coli
CLNS1A Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is Q28678.
TMPH-03205 HINT1 Protein, Rabbit, Recombinant (His & Myc)

HINT1,Histidine triad nucleotide-binding protein 1,Desumoyla...

Rabbit HEK293 Cells
HINT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession number is P80912.
TMPK-01310 Syndecan-1 Protein, Rabbit, Recombinant (His)

SDC1,SYND1,SDC,CD138,Syndecan 1

Rabbit HEK293 Cells
CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
TMPH-03206 ITGB8 Protein, Rabbit, Recombinant (His & Myc)

ITGB8,Integrin beta-8

Rabbit E. coli
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis. ITGB8 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli ...
TMPY-02697 IgG Protein, Rabbit, Recombinant (T185A, N284S)

IgG

Rabbit HEK293 Cells
IgG Protein, Rabbit, Recombinant (T185A, N284S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25 kDa and the accession number is P01870.
TMPY-04011 IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant

白介素,IL1-β,interleukin 1, beta,interleukin 1, β,IL-1 β,白细胞介素,...

Rabbit E. coli
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P14628.
TMPH-03215 OX40L/TNFSF4 Protein, Rabbit, Recombinant (hFc)

TNFSF4,OX40 ligand,Tumor necrosis factor ligand superfamily ...

Rabbit HEK293 Cells
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O02765.
TMPH-03216 OX40L/TNFSF4 Protein, Rabbit, Recombinant (His)

Tumor necrosis factor ligand superfamily member 4,TNFSF4,OX4...

Rabbit E. coli
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.1 kDa and the accession number is O02765.
TMPH-03214 OX40L/TNFSF4 Protein, Rabbit, Recombinant (His & Myc)

Tumor necrosis factor ligand superfamily member 4,TNFSF4,OX4...

Rabbit P. pastoris (Yeast)
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His & Myc) is expressed in yeast with C-6xHis, Myc tag. The predicted molecular weight is 19.8 kDa and the accession number is O02765.
TMPH-03200 CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His)

CD40LG,Tumor necrosis factor ligand superfamily member 5,TNL...

Rabbit E. coli
N/A. CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.2 kDa and the accession number is G1SKP7.
TMPH-03213 TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)

Tropomyosin alpha-1 chain,TPM1,Alpha-tropomyosin,Tropomyosin...

Rabbit E. coli
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular w...
TMPY-06750 IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)

interleukin 18 receptor accessory protein,IL-18R β/IL-18RAP

Rabbit HEK293 Cells
IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.22 kDa and the accession number is G1SQ92.
TMPY-00105 Recombinant Protein G

E. coli
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig...
TMPY-03758 Vaccinia Virus B18R/B19R Protein (His)

VACV Baculovirus Insect Cells
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R has a broad species specificity. It has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. It has been shown that secreted B18R binds to un...
TMPH-00825 Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc)

Agglutinin,Mannose-specific lectin,Horcolin

Domesticated barley E. coli
Mannose-specific lectin. Has a weak agglutinating activity against rabbit erythrocytes. Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is P82953.
TMPH-00173 Subtilosin-A Protein, Bacillus subtilis, Recombinant (His & KSI)

sboA,Antilisterial bacteriocin subtilosin,Subtilosin-A

Bacillus subtilis E. coli
Has bacteriocidal activity against some Gram-positive bacteria such as Listeria, some species of Bacillus and E.faecium. A single mutation (Thr-14-Ile) confers hemolytic activity against rabbit and human blood. Subtilosin-A Protein, Bacillus subtilis, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.8 kDa and the accession number is O07623.
TMPH-03069 CSL3 Protein, Oncorhynchus keta, Recombinant (His)

L-rhamnose-binding lectin CSL3

Oncorhynchus keta E. coli
L-rhamnose binding lectin. Has hemagglutinating activity towards rabbit erythrocytes, human type A erythrocytes, human type B erythrocytes, human type O erythrocytes and sheep erythrocytes. Hemagglutinating activity is inhibited by smooth-type lipopolysaccharide (LPS) from S.flexneri 1A, A.salmonicida and E.coli K12, but not by rough-type LPS from S.flexneri, E.coli K12 and E.coli EH100. Agglutinates E.coli K12 and B.subtilis.
TMPK-00974 SP17 Protein, Human, Recombinant (His)

Sperm protein 17,SPA17,CT22,Sp17-1

Human E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. SP17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 1...
TMPK-01035 SP17 Protein, Mouse, Recombinant (His)

SPA17,Sperm protein 17,CT22,Sp17-1

Mouse E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. SP17 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 1...
TMPY-04964 Recombinant Protein A, HRP conjugate

Protein A is surface protein originally found in the cell wall of the bacteria Staphylococcusaureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two component system called ArlS-ArlR. Protein A binds the Fc region of various mammalian IgG subclasses including: Human IgG1, IgG2, IgG3 (weakly), IgG4 Mouse IgG1 (weakly), IgG2a, IgG2b, IgG3 SPA also binds IgG from monkey, rabbit, pig, guinea pig, dog, rat and cat. It also weakly binds to...
TMPY-03269 Prolyl Endopeptidase Protein, Mouse, Recombinant (His)

PEP,AI450383,AI047692,D10Wsu136e,prolyl endopeptidase,Pop

Mouse Baculovirus Insect Cells
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotens...
TMPJ-01316 IL-21 Protein, Mouse, Recombinant (His)

白细胞介素,IL-21,Interleukin-21,白介素,IL21

Mouse E. coli
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, respectively. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex (IL-21 specific IL-21 R). IL-21 is a cytokine that has potent regulatory effects on cells of the immun...

重组蛋白

TNF alpha Protein, Rabbit, Recombinant
Cat.No: TMPJ-00779
Species: Rabbit
Expression System: E. coli
CD38 Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-03634
Species: Rabbit
Expression System: HEK293 Cells
DAG1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03202
Species: Rabbit
Expression System: E. coli
TFPI Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03211
Species: Rabbit
Expression System: HEK293 Cells
IL-17 Protein, Rabbit, Recombinant
Cat.No: TMPY-04888
Species: Rabbit
Expression System: E. coli
TrkA Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-04663
Species: Rabbit
Expression System: HEK293 Cells
VEGFA Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03217
Species: Rabbit
Expression System: P. pastoris (Yeast)
IL-17 Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-04609
Species: Rabbit
Expression System: Baculovirus Insect Cells
B7-2 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00959
Species: Rabbit
Expression System: HEK293 Cells
TPM1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03212
Species: Rabbit
Expression System: Baculovirus Insect Cells
VEGFA Protein, Rabbit, Recombinant (His & SUMO)
Cat.No: TMPH-03218
Species: Rabbit
Expression System: E. coli
MGAT1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03198
Species: Rabbit
Expression System: E. coli
B7-1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPJ-00958
Species: Rabbit
Expression System: HEK293 Cells
NGFR/p75NTR Protein, Rabbit, Recombinant (hFc)
Cat.No: TMPY-04831
Species: Rabbit
Expression System: HEK293 Cells
IL-23 Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-04792
Species: Rabbit
Expression System: HEK293 Cells
FGFb Protein, Rabbit, Recombinant (His & SUMO)
Cat.No: TMPH-03203
Species: Rabbit
Expression System: E. coli
IL-12B Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-00259
Species: Rabbit
Expression System: HEK293 Cells
TFPI Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03210
Species: Rabbit
Expression System: E. coli
IL-6 Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03208
Species: Rabbit
Expression System: P. pastoris (Yeast)
IL-2 Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03207
Species: Rabbit
Expression System: E. coli
CD64A Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-05287
Species: Rabbit
Expression System: HEK293 Cells
APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03199
Species: Rabbit
Expression System: E. coli
NGFR/p75NTR Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-04646
Species: Rabbit
Expression System: HEK293 Cells
Ory c 3 Protein, Rabbit, Recombinant
Cat.No: TMPY-06738
Species: Rabbit
Expression System: P. pastoris (Yeast)
Tissue Factor Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-02318
Species: Rabbit
Expression System: HEK293 Cells
GHR Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03204
Species: Rabbit
Expression System: E. coli
CD40 Ligand Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03201
Species: Rabbit
Expression System: P. pastoris (Yeast)
CLNS1A Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03209
Species: Rabbit
Expression System: E. coli
HINT1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03205
Species: Rabbit
Expression System: HEK293 Cells
Syndecan-1 Protein, Rabbit, Recombinant (His)
Cat.No: TMPK-01310
Species: Rabbit
Expression System: HEK293 Cells
ITGB8 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03206
Species: Rabbit
Expression System: E. coli
IgG Protein, Rabbit, Recombinant (T185A, N284S)
Cat.No: TMPY-02697
Species: Rabbit
Expression System: HEK293 Cells
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant
Cat.No: TMPY-04011
Species: Rabbit
Expression System: E. coli
OX40L/TNFSF4 Protein, Rabbit, Recombinant (hFc)
Cat.No: TMPH-03215
Species: Rabbit
Expression System: HEK293 Cells
OX40L/TNFSF4 Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03216
Species: Rabbit
Expression System: E. coli
OX40L/TNFSF4 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03214
Species: Rabbit
Expression System: P. pastoris (Yeast)
CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03200
Species: Rabbit
Expression System: E. coli
TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03213
Species: Rabbit
Expression System: E. coli
IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-06750
Species: Rabbit
Expression System: HEK293 Cells
Recombinant Protein G
Cat.No: TMPY-00105
Species:
Expression System: E. coli
Vaccinia Virus B18R/B19R Protein (His)
Cat.No: TMPY-03758
Species: VACV
Expression System: Baculovirus Insect Cells
Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc)
Cat.No: TMPH-00825
Species: Domesticated barley
Expression System: E. coli
Subtilosin-A Protein, Bacillus subtilis, Recombinant (His & KSI)
Cat.No: TMPH-00173
Species: Bacillus subtilis
Expression System: E. coli
CSL3 Protein, Oncorhynchus keta, Recombinant (His)
Cat.No: TMPH-03069
Species: Oncorhynchus keta
Expression System: E. coli
SP17 Protein, Human, Recombinant (His)
Cat.No: TMPK-00974
Species: Human
Expression System: E. coli
SP17 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01035
Species: Mouse
Expression System: E. coli
Recombinant Protein A, HRP conjugate
Cat.No: TMPY-04964
Species:
Expression System:
Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03269
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-21 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01316
Species: Mouse
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
T10349 Apixaban 13C,d3

Apixaban 13CD3,BMS-562247-01 13CD3

Others Others
Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit).
T70883 Moexipril-d5

Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ...
T71402 Nicorandil-d4

Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...

同位素标记化合物

Apixaban 13C,d3
Cat.No: T10349
Synonym: Apixaban 13CD3,BMS-562247-01 13CD3
Target: Others
Moexipril-d5
Cat.No: T70883
Synonym:
Target:
Nicorandil-d4
Cat.No: T71402
Synonym:
Target:
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