olive

Oleuropeinic acid 是一种抗氧化剂可溶性纤维，存在于橄榄组织中或通过热处理形成，可能是由橄榄苦苷的氧化形成。

Oleuropein 在橄榄叶和油中发现的天然产物，通过 p53 依赖性途径以及 Bax 和 Bcl2基因的调控来诱导乳腺癌细胞凋亡，还抑制芳香化酶。它可通过直接抑制 PPARγ转录活性来发挥抗氧化，抗炎和抗动脉粥样硬化作用。

Colivelin 是一种神经保护肽和 STAT3 的激活剂，是一种合成的杂合肽，可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡，具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。

Olivetolic acid (OLA)  是一种来自大麻中大麻素的前体，在Dravet综合征的小鼠模型中显示抗惊厥活性。Olivetolic acid 具有潜在的抗菌活性。

Olivetol (5-n-Amylresorcinol) 是天然多酚类化合物，存在于地衣中，或由一些昆虫产生。它竞争性地抑制大麻素受体CB1和CB2，抑制 CYP2C19 (IC50=15.3 μM;Ki=7.21 μM) 和 CYP2D6 (IC50=2.71 μM;Ki=2.87 μM) 的活性。

Olivetol Dimethyl Ether 是一种单酰基甘油，具有镇痛活性和潜在的抗炎活性，可以抑制脂肪酸的合成。

Oliveroline, 一种存在于植物中的生物碱，表现出对Topo I的强效抑制以及对Topo II的卓越抑制能力，其效果超过了类似化合物如topotecan和etoposide。与Topo II形成的复合物相比Topo I显示出更好的稳定性，表明其作为癌症治疗进一步研究的有力候选物。

Colivelin (TFA) is a hybrid peptide composed of ADNF and AGA-(C8R)HNG17, a potent Humanin (HN) derivative.

Urolithin M5 (Decarboxyellagic acid) 是一种从橄榄叶中分离得到的神经氨酸酶抑制剂，具有抗病毒和抗癌抗肿瘤活性。Urolithin M5 可用于研究甲型流感病毒感染和 SARS-CoV-2 感染。

4-Hydroxycyclohexanecarboxylic acid 是环己烷羧酸的底物，是从橄榄盐水中分离出的化合物。

Hydroxytyrosol (2-(3,4-Di-hydroxyphenyl)-ethanol) 是从橄榄树及其叶子中提取的一种酚类化合物，具有抗氧化、抗动脉粥样硬化、抗血栓、抗菌、抗炎和抗肿瘤的作用，可用于研究心血管药物。

Homovanillyl alcohol 是羟基酪醇的生物代谢物。Hydroxytyrosol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤，并对心血管具有保护作用。

Fucoxanthin (all-trans-Fucoxanthin) 是海洋类胡萝卜素，具有抗肥胖，抗糖尿病，抗炎，抗氧化，抗癌等作用。

Hydroxytyrosol Acetate (HTy-Ac) 是从橄榄油中发现的，具有抗氧化作用。它清除 DPPH 自由基的活性比 hydroxytyrosol 弱。

RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) 是一种新型昆虫生长调节剂，可用作控制橄榄果蝇的潜在杀虫剂。

δ7-Avenasterol is a phytosterol that has been found in a variety of plant oils and grains, including olive and soybean oils and wheat, oats, and rye, and has antioxidant activities.1,2It reduces temperature-induced oxidation of safflower oil.3

rac-1,2-bis-Palmitoyl-3-chloropropanediol is a 3-monochloropropane-1,2-diol (3-MCPD) ester.1It has been found as a contaminant in edible olive oils, with the lowest and highest concentrations in extra virgin and olive pomace oils, respectively.rac-1,2-bis-Palmitoyl-3-chloropropanediol has also been found in cottonseed and palm oils, as well as in shortening.2It induces renal tubular necrosis and a decrease in spermatids, but no gross pathological changes, in mice.3 1.Hung, W.-C., Peng, G.-J., Tsai, W.-J., et al.Identification of 3-MCPD esters to verify the adulteration of extra virgin olive oilFood Addit. Contam. Part B Surveill.10(3)233-239(2017) 2.MacMahon, S., Begley, T.H., and Diachenko, G.W.Occurrence of 3-MCPD and glycidyl esters in edible oils in the United StatesFood Addit. Contam. Part A. Chem. Anal. Control Expo. Risk Assess.30(12)2081-2092(2013) 3.Liu, M., Gao, B.-Y., Qin, F., et al.Acute oral toxicity of 3-MCPD mono- and di-palmitic esters in Swiss mice and their cytotoxicity in NRK-52E rat kidney cellsFood Chem. Toxicol.50(10)3785-3791(2012)

6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transporter substrate, across Caco-2 cell monolayers (IC50 = 0.7 μM). 6'7'-Epoxybergamottin also has insecticidal properties with a concentration of 5 μg/cm2 leading to 100% mortality of adult olive fruit flies.

Cycloolivil (Isoolivil) 是一种天然多酚化合物，在橄榄树中具有显着的自由基清除活性。 Cycloolivil 具有抗氧化活性，它可以预防与血小板过度聚集相关的血栓并发症，是开发抗聚集治疗策略的基础。

Erythrodiol 是一种橄榄油的成分，能够选择性抑制ABCA1蛋白的降解来促进胆固醇外流，有用于动脉粥样硬化的研究潜力。

POL, a prevalent triglyceride component in various seed and vegetable oils such as olive, sesame, soybean, canola, corn, and hazelnut, is standardly utilized in the USP analysis of sesame oil for pharmaceutical applications.

1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.

1,2-Dilinoleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol featuring linoleic acid at the sn-1 and sn-2 positions and palmitic acid at the sn-3 position. Present in various vegetable oils such as poppy seed, hazelnut, maize, and olive, this compound (3% w v) effectively reduces scald development in Delicious apples when applied right after harvest, with results observed after six months of storage.

1,2,3-Tri-11(Z)-eicosenoyl glycerol, a triacylglycerol with 11(Z)-eicosenoic acid at the sn-1,sn-2, and sn-3 positions, serves as an internal standard for quantifying triacylglycerols in seed and olive oils.