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Search Results for " oligomerization "

Targets Recommended: IRE1

30

抑制剂 & 化合物

1

天然产物

17

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9564	IRE1α kinase-IN-1	IRE1	Cell Cycle/Checkpoint
	IRE1α kinase-IN-1 是IRE1α 的选择性抑制剂(IC50为 77 nM)，对 IRE1α 的选择性高于 IRE1β 亚型 100 倍。它抑制内质网诱导的 IRE1α 寡聚和自磷酸化，并抑制 IRE1α RNase 活性 (IC50=80 nM)。
T38361	GSK717	IL Receptor; NOD	Immunology/Inflammation; NF-κB
	GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导，抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T30479	Bis-T-23 Bis T-23,Bis-T 23,AG1717	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Bis-T-23是一种肌动蛋白依赖性达纳敏低聚物的促进剂，是一种 HIV-I 整合酶抑制剂，是泰尔普斯丁衍生物。Bis-T-23可以促进肌动蛋白依赖性的dynamin 寡聚化。Bis-T-23可用于HIV 和慢性肾脏疾病（CKD）的研究。
T3587	NOD-IN-1 Compound 4	NOD-like Receptor (NLR); NOD	Immunology/Inflammation; NF-κB
	NOD-IN-1 (Compound 4) 是核苷酸结合寡聚化结构域样受体 NOD1(IC50:5.74 μM)和 NOD2 (IC50:6.45 μM)的抑制剂。
T13287	VBIT-4	VDAC	Membrane transporter/Ion channel
	VBIT-4 是一种电压依赖性阴离子通道 1 (VDAC1) 寡聚化抑制剂 (Kd=17 μM)。VBIT-4 可以预防线粒体功能障碍和细胞凋亡，并恢复细胞能量和代谢。VBIT-4 可用于治疗神经退行性疾病和心血管疾病。
T84345	WJ-39 WJ39,WJ 39	Reductase	Endocrinology/Hormones; Metabolism
	WJ-39 是一种具有口服活性的醛糖还原酶 (AR) 抑制剂，通过激活 Nrf2 信号传导来改善糖尿病肾病的肾脏病变，可用于改善肾功能不全和纤维化。WJ-39 抑制氧化应激，抑制寡聚化结构域样受体家族pyrin结构域3(NLRP3)炎症小体的激活。
T14884	CBR-5884	Others; Dehydrogenase	Metabolism; Others
	CBR-5884 是一种磷酸甘油酸脱氢酶抑制剂，IC50为 33 μM。它抑制癌细胞中的丝氨酸合成，选择性地抑制黑素瘤和乳腺癌细胞系的增殖，对具有高丝氨酸生物合成活性的癌细胞系有选择性毒性。
T60442	NLRP3/AIM2-IN-3	NOD; AIM2	Immunology/Inflammation; NF-κB
	NLRP3/AIM2-IN-3 是一种独特的分子，能以物种特异性的方式抑制 NLRP3 和 AIM2 炎性体的激活。它对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3是一种 NLRP3 和 AIM2 炎症体依赖性细胞裂解的强效抑制剂，对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3 可抑制 LPS/nigericin 刺激的 THP-1 巨噬细胞的细胞裂解，其 IC50 值为 0.077 ± 0.008 μM。NLRP3/AIM2-IN-3 干扰了 NLRP3 或 AIM2 与桥接蛋白 ASC 的相互作用，抑制了 ASC 的寡聚。
T35841	5-Benzyloxygramine	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂，具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体，可拮抗 5-HT 对大鼠子宫和兔耳的作用。
T28117	MSN-50 MSN50,MSN 50	Others	Others
	MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.
T79752	DDC 2′,3′-O-disulfate	Others	Others
	DDC 2′,3′-O-disulfate (compound 4) 可防止Aβ42纤维化和寡聚化，显示出在阿尔茨海默病（AD）研究中的应用潜力。
T78689	hAChE-IN-1	Others	Others
	hAChE-IN-1（Compound 24）作为一种有效的hAChE抑制剂，显示出1.09 μM的IC50值。进一步，在细胞tau FRET实验中，该化合物对tau寡聚具有抑制作用，其EC50为2.71 μM。
T14150	AKOS-22	Others	Others
	AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 protects against mitochondrial dysfunction[1]. AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis.
T78692	hAChE-IN-2	Others	Others
	hAChE-IN-2为一种有效抑制hAChE的化合物，具有0.71 μM的IC50，并对tau寡聚化展现出抑制作用，其EC50为2.21 μM。此外，hAChE-IN-2亦显示出神经保护活性。
T16155	MSN-125	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochond
T28223	OB-1	Others	Others
	OB-1 is an inhibitor of stomatin-like protein-3 (STOML3) oligomerization. OB-1 reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in vivo.
T28224	OB-2	Others	Others
	OB-2 is an inhibitor of stomatin-like protein-3 (STOML3) oligomerization. OB-2 reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in vivo.
T13286	VBIT-3	Others	Others
	VBIT-3 is a voltage-dependent anion channel 1 (VDAC1) oligomerization inhibitor (Kd: 31.3 μM). VBIT-3 also is an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders (such as neurodegenerative and cardiovascular diseases).
T82621	D359-0396	NOD-like Receptor (NLR)	Immunology/Inflammation
	D359-0396 是一种口服活性的 NLRP3 炎性体抑制剂，能有效抑制巨噬细胞焦亡（pyroptosis）以及 IL-1β 的释放，并阻止 NLRP3 和 ASC 的寡聚化，抑制 GSDMD 的裂解。该化合物在动物模型中能减轻小鼠的 EAE 症状，并提高感染性休克后的小鼠存活率。
T71527	NSC145366	Others	Others
	NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in allosteric inhibition of NTD ATPase activity (IC50=119μM) but does not compete with NTD or CTD-ATP binding.
T63717	CAM833	Others	Others
	CAM833 是有效的抑制 BRCA2 和 RAD51 之间相互作用的正位抑制剂，也能够抑制 RAD51 的寡聚，能够作用于 ChimRAD51 蛋白 (Kd: 366 nM)。
T83509	[Arg6]-β-Amyloid (1-40), england mutation
	[Arg6]-β-Amyloid (1-40), England mutation 是具有生物活性的肽，与多种家族性常染色体显性阿尔茨海默病相关。特别地，这种英国突变，即位于第6位的His被Arg所替换，已报告可提高寡聚体形成动力学，加速初级纤维的种子化过程。此类寡聚体对神经元培养细胞展现出较高毒性。
T78894	NLRP3-IN-21	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-21（compound L38）是一款NLRP3炎症体抑制剂，具抗炎特性。此化合物能够抑制gasdermin D裂解、防止ASC寡聚化，并阻止NLRP3炎症小体的组装，从而遏制NLRP3炎症小体的激活及焦亡过程。
T82599	DDC 3′-O-β-D glucuronide	Drug Metabolite	Metabolism
	DDC 3′-O-β-D glucuronide（化合物5）作为一种药物代谢物，具备抑制Aβ42纤维化及其寡聚化的能力，表现出在阿尔茨海默病研究中的应用潜力。
T11207	Entacapone sodium salt	Others	Others
	Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapone (< 100 μM) is a potent inhibitor of α-syn and β-amyloid (Aβ) oligomerization and fibrillogenesis, and also protects against extracellular toxicity induced by the aggregation of both proteins in PC12 cells.Entacapone sodium salt is a specific, potent, peripherally acting catech...
T72473	NOD1/2 antagonist-1	Others	Others
	NOD1/2 antagonist-1 是一种有效的NOD1/2双拮抗剂，其IC50值分别为 1.13 (NOD1) 和 0.77 μM (NOD2)。NOD1/2 antagonist-1 有可接受的 T1/2(67.6 min)。NOD1/2 antagonist-1 可提高紫杉醇 (PTX) 的抗肿瘤作用。
T83751	PUMA BH3 (human) TFA
	PUMA BH3是一个由p53上调凋亡调节器(PUMA)的BH3域组成的肽，并激活促凋亡蛋白Bak。PUMA BH3与Bak结合（在HEPES和CHAPS缓冲液中的Kds分别为290和26 nM），诱导Bak同源寡聚化和Bak介导的膜透性增加。
T78784	RIPK3-IN-3	Others	Others
	RIPK3-IN-3（化合物20）是一种针对受体相互作用蛋白激酶RIPK3的选择性抑制剂，其IC50为10 nM。它通过抑制p-MLKL的寡聚化作用来阻止RIPK3介导的MLKL磷酸化以及随后的坏死性凋亡。此外，RIPK3-IN-3还能降低CXCL5的分泌，并抑制AsPC-1细胞的迁移和侵袭。
T62506	3,6-DMAD dihydrochloride	Others	Others
	3,6-DMAD dihydrochloride 是一种吖啶衍生物，是一种 IRE1α-XBP1s 通路的有效抑制剂。3,6-DMAD dihydrochloride 可以利用 IRE1α-XBP1s 通路，诱导 IL-6 分泌。3,6-DMAD dihydrochloride 对 IRE1α 寡聚化和核糖核酸内切酶 (RNase) 活性具有抑制作用。3,6-DMAD dihydrochloride 能够用于研究癌症。
T79731	MLKL-IN-6	Necroptosis	Apoptosis
	MLKL-IN-6（compound P28）是一种针对Mixed Lineage Kinase domain-like（MLKL）的混合谱系激酶抑制剂，具有抗纤维化的潜力。它能够抑制MLKL的磷酸化和寡聚化，从而抑制细胞坏死、免疫细胞死亡，并减少粘附因子的表达。MLKL-IN-6展现出低细胞毒性，并可抑制肝星状细胞的激活，从而降低肝纤维化标志物的水平。

化合物

IRE1α kinase-IN-1

Cat.No: T9564

Target: IRE1

Cat.No: T38361

Target: IL Receptor, NOD

Cat.No: T30479

Synonym: Bis T-23,Bis-T 23,AG1717

Target: HIV Protease

Cat.No: T3587

Synonym: Compound 4

Target: NOD-like Receptor (NLR), NOD

Cat.No: T13287

Target: VDAC

Cat.No: T84345

Synonym: WJ39,WJ 39

Target: Reductase

Cat.No: T14884

Target: Others, Dehydrogenase

NLRP3/AIM2-IN-3

Cat.No: T60442

Target: NOD, AIM2

5-Benzyloxygramine

Cat.No: T35841

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T28117

Synonym: MSN50,MSN 50

Target: Others

DDC 2′,3′-O-disulfate

Cat.No: T79752

Target: Others

Cat.No: T78689

Target: Others

Cat.No: T14150

Target: Others

Cat.No: T78692

Target: Others

Cat.No: T16155

Target: Akt

Cat.No: T28223

Target: Others

Cat.No: T28224

Target: Others

Cat.No: T13286

Target: Others

Cat.No: T82621

Target: NOD-like Receptor (NLR)

Cat.No: T71527

Target: Others

Cat.No: T63717

Target: Others

[Arg6]-β-Amyloid (1-40), england mutation

Cat.No: T83509

Cat.No: T78894

Target: NOD-like Receptor (NLR)

DDC 3′-O-β-D glucuronide

Cat.No: T82599

Target: Drug Metabolite

Entacapone sodium salt

Cat.No: T11207

Target: Others

NOD1/2 antagonist-1

Cat.No: T72473

Target: Others

PUMA BH3 (human) TFA

Cat.No: T83751

Cat.No: T78784

Target: Others

3,6-DMAD dihydrochloride

Cat.No: T62506

Target: Others

Cat.No: T79731

Target: Necroptosis

Cat. No.	Product Name	Target	Signaling Pathways
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。

天然产物

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00289	NOD2 Protein, Bovine, Recombinant (His & KSI) Caspase recruitment domain-containing protein 15,Nucleotide-...	Bovine	E. coli
	NOD2 Protein, Bovine, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 36.8 kDa and the accession number is Q6E804.
TMPH-03522	Alpha-hemolysin Protein, S. aureus, Recombinant (His) Alpha-toxin,Alpha-HL	Staphylococcus aureus	P. pastoris (Yeast)
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity.
TMPJ-00993	CCL5 Protein, Rat, Recombinant (E. coli, His) Small-inducible cytokine A5,SIS-δ,C-C motif chemokine 5,T-ce...	Rat	E. coli
	C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory sites, and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. Inflammatory responses can be impaired by the sequestration of CCL5 by the cytomegalovirus protein US28. Oligomerization of CCL5 on glycosaminoglycans is required for CCR1mediated leu...
TMPH-03523	Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO) Alpha-HL,Alpha-toxin	Staphylococcus aureus	E. coli
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity.
TMPY-02551	CCDC134 Protein, Human, Recombinant (His) coiled-coil domain containing 134	Human	HEK293 Cells
	Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcription factors, intermediate filaments and certain tRNA synthetases. Many proteins containing such motif CCDC134 are involved in important biological functions. CCDC134 is also considered as a novel human MAPK-regulating protein that can inhibit the MAPK pathway. This protein signi...
TMPH-02661	Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His) Fxn,Frataxin, mitochondrial	Mouse	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit...
TMPH-02660	Frataxin/FXN Protein, Mouse, Recombinant (His) Fxn,Frataxin, mitochondrial	Mouse	P. pastoris (Yeast)
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit...
TMPY-03501	Optineurin Protein, Human, Recombinant (His & GST) optineurin,HIP7,ALS12,HYPL,TFIIIA-INTP,FIP2,NRP,GLC1E	Human	Baculovirus Insect Cells
	OPTN (Optineurin) is a Protein Coding gene. The Optineurin gene encodes the coiled-coil containing protein optineurin. Optineurin is a multifunctional adaptor protein intimately involved in various vesicular trafficking pathways. Through interactions with an array of proteins, such as myosin VI, huntingtin, Rab8, and Tank-binding kinase 1, as well as via its oligomerization, optineurin can act as an adaptor, scaffold, or signal regulator to coordinate many cellular processes associated with the ...
TMPH-02249	TRIM72 Protein, Human, Recombinant (E. coli, His & Myc) Mitsugumin-53,Tripartite motif-containing protein 72,TRIM72	Human	E. coli
	Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch fo...
TMPH-01502	Humanin Protein, Human, Recombinant (GST) Humanin,Humanin mitochondrial,MT-RNR2	Human	E. coli
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPH-02878	PTPRS Protein, Mouse, Recombinant (His & Myc) Receptor-type tyrosine-protein phosphatase S,Ptprs,PTPNU-3,R...	Mouse	E. coli
	Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteo...
TMPJ-00789	Flagellin Protein, Salmonella Typhimurium, Recombinant flaF,Phase 1-I flagellin,Flagellin,fliC,hag	Salmonella typhimurium	E. coli
	Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin is used as an effective systemic or mucosal adjuvant to stimulate the immune system. Flagellin is an agonist of Toll-like receptor 5 (TLR5), a pattern recognition receptor (PRR) of the innate immune system expressed on the basolateral surface of intestinal epithelial cells and o...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST) mitogen-activated protein kinase kinase kinase kinase 2,GCK,...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein, and MAP4K2, is cytoplasm and peripheral membrane protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its express...
TMPH-01503	Humanin Protein, Human, Recombinant (hFc) MT-RNR2,Humanin,Humanin mitochondrial	Human	HEK293 Cells
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation....
TMPY-04385	ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) death-associated protein kinase 3,DLK,ZIP,ZIPK	Human	Baculovirus Insect Cells
	Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. DAPK3 / ZIPK contains oneprotein kinase domain. It is a serine/threonine kinase which acts as a positive regulator of apoptosis. It phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. DAPK3 / ZIPK is a homodimer or forms heterodimers with AT...
TMPY-02228	p53 Protein, Cynomolgus, Recombinant tumor protein p53,p53,TP53	Cynomolgus	E. coli
	p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 (TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damag...
TMPH-00616	DNA-binding protein H-NS Protein, E. coli, Recombinant (His) hns,DNA-binding protein H-NS,Protein B1,Protein H1,Heat-stab...	E. coli	E. coli
	A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstream and downstream of initiating RNA polymerase, trapping it in a loop and preventing transcription. Binds to hundreds of sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Many of these loci were horizontally transfe...

重组蛋白

NOD2 Protein, Bovine, Recombinant (His & KSI)

Cat.No: TMPH-00289

Species: Bovine

Expression System: E. coli

Alpha-hemolysin Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03522

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

CCL5 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPJ-00993

Species: Rat

Expression System: E. coli

Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03523

Species: Staphylococcus aureus

Expression System: E. coli

CCDC134 Protein, Human, Recombinant (His)

Cat.No: TMPY-02551

Species: Human

Expression System: HEK293 Cells

Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02661

Species: Mouse

Expression System: E. coli

Frataxin/FXN Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02660

Species: Mouse

Expression System: P. pastoris (Yeast)

Optineurin Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03501

Species: Human

Expression System: Baculovirus Insect Cells

TRIM72 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02249

Species: Human

Expression System: E. coli

Humanin Protein, Human, Recombinant (GST)

Cat.No: TMPH-01502

Species: Human

Expression System: E. coli

PTPRS Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02878

Species: Mouse

Expression System: E. coli

Flagellin Protein, Salmonella Typhimurium, Recombinant

Cat.No: TMPJ-00789

Species: Salmonella typhimurium

Expression System: E. coli

Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04412

Species: Human

Expression System: Baculovirus Insect Cells

Humanin Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01503

Species: Human

Expression System: HEK293 Cells

ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04385

Species: Human

Expression System: Baculovirus Insect Cells

p53 Protein, Cynomolgus, Recombinant

Cat.No: TMPY-02228

Species: Cynomolgus

Expression System: E. coli

DNA-binding protein H-NS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00616

Species: E. coli

Expression System: E. coli

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