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Search Results for " enzyme modulator "

Targets Recommended: Others

3

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T24116	GSM-1 gamma Secretase modulator 1,GSM 1 (enzyme modulator),J2.559.799K	Others	Others
	GSM-1 is a modulator of γ-Secretase.
T6509	Galeterone VN-124-1,TOK-001,VN/124-1,VN 124	P450; Androgen Receptor	Endocrinology/Hormones; Metabolism
	Galeterone (VN 124) 是CYP17抑制剂，能够多功能的抗雄激素，在去势抵抗性前列腺癌中，其IC50值为 47 nM。
T71578	Endoxifen mesylate	Others	Others
	Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromat...

化合物

Cat.No: T24116

Synonym: gamma Secretase modulator 1,GSM 1 (enzyme modulator),J2.559.799K

Target: Others

Cat.No: T6509

Synonym: VN-124-1,TOK-001,VN/124-1,VN 124

Target: P450, Androgen Receptor

Endoxifen mesylate

Cat.No: T71578

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01336	SENP2 Protein, Human, Recombinant Sentrin/SUMO-specific protease SENP2,Axam2,SMT3-specific iso...	Human	E. coli
	SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
TMPY-02394	IMPA1 Protein, Human, Recombinant (His) IMPA,inositol(myo)-1(or 4)-monophosphatase 1,IMP	Human	E. coli
	IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Ad...

重组蛋白

SENP2 Protein, Human, Recombinant

Cat.No: TMPJ-01336

Species: Human

Expression System: E. coli

IMPA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02394

Species: Human

Expression System: E. coli

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