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Search Results for " derivatives "
Targets Recommended: Amino Acids and Derivatives Others

561

抑制剂 & 化合物

70

天然产物

13

化合物库

17

重组蛋白

6

同位素标记化合物

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Cat. No. Product Name
NY1000 天然产物衍生物库

4000 compounds
22个天然产物骨架,3745个天然产物衍生物;
L6030 天然产物衍生物虚筛化合物库

163000 compounds
16.3万种天然产物衍生物,并且在持续增加中;
L6900 稀有天然产物库

693 compounds
693 种稀有天然产物的集合,可以用于高通量和高内涵筛选;
L6140 糖类及苷类化合物库

595 compounds
595 种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选;
L9820 β-内酰胺类化合物库

97 compounds
97 种β-内酰胺类化合物的集合,可以用于高通量和高内涵筛选;
L2400 内分泌激素分子库

784 compounds
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L6150 天然产物共价化合物库

583 compounds
提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础;
L6130 萜类天然产物库

622 compounds
622 种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L6700 抗癌天然产物库

1772 compounds
1772 种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS 和HCS。
L4700 免疫/炎症分子化合物库

4720 compounds
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选;
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;
L6500 微生物天然产物库

685 compounds
685 种微生物来源的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L6000 高通量筛选天然产物库

4533 compounds
4533 种天然产物的独特集合,是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具,可用于HTS 和HCS;

化合物库

天然产物衍生物库
Cat.No: NY1000
Compounds: 4000
天然产物衍生物虚筛化合物库
Cat.No: L6030
Compounds: 163000
稀有天然产物库
Cat.No: L6900
Compounds: 693
糖类及苷类化合物库
Cat.No: L6140
Compounds: 595
β-内酰胺类化合物库
Cat.No: L9820
Compounds: 97
内分泌激素分子库
Cat.No: L2400
Compounds: 784
天然产物共价化合物库
Cat.No: L6150
Compounds: 583
萜类天然产物库
Cat.No: L6130
Compounds: 622
抗癌天然产物库
Cat.No: L6700
Compounds: 1772
免疫/炎症分子化合物库
Cat.No: L4700
Compounds: 4720
脂代谢化合物库
Cat.No: L2510
Compounds: 492
微生物天然产物库
Cat.No: L6500
Compounds: 685
高通量筛选天然产物库
Cat.No: L6000
Compounds: 4533
Cat. No. Product Name Target Signaling Pathways
T13145 Thiazolidinone-Derivatives-1

Others Others
Thiazolidinone-Derivatives-1 抑制胃酸分泌,可用于研究胃和十二指肠溃疡的治疗。
T67717L Questiomycin A derivatives 18 TFA

Others Others
Questiomycin A derivatives 18 TFA 是一种Questiomycin A 衍生物,Questiomycin A 具有抗菌和抗癌活性 ,对细胞保护性 ER 伴侣蛋白 GRP78 的表达具有抑制作用。
T67720 Questiomycin A derivatives 21

Others Others
Questiomycin A derivatives 21 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67720,CAS号为 1807725-36-5。
T77738L Questiomycin A derivatives 35 HCl

Phx-3 derivatives 35 HCl

Others Others
T67723 Questiomycin A derivatives 24

Others Others
Questiomycin A derivatives 24 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67723,CAS号为 21033-44-3。
T67721 Questiomycin A derivatives 22

Others Others
Questiomycin A derivatives 22 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67721,CAS号为 1807725-35-4。
T19226 Calcitriol Derivatives

Others Others
Calcitriol Derivatives is an analog of vitamin D3.
T67712 Questiomycin A derivatives 13

Others Others
Questiomycin A derivatives 13 是一种 Questiomycin A 衍生物。
T67711 Questiomycin A derivatives 12

Others Others
Questiomycin A derivatives 12 是一种Questiomycin A 衍生物。
T67713 Questiomycin A derivatives 14

Others Others
Questiomycin A derivatives 14 是一种 Questiomycin A 衍生物。
T67719 Questiomycin A derivatives 20

Others Others
Questiomycin A derivatives 20 是一种Questiomycin A 衍生物。
T72086 Questiomycin A derivatives 27

Others Others
Questiomycin A derivatives 27 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T72086。
T8866 GW779439X

Apoptosis; Antibacterial; CDK; Aurora Kinase Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Microbiology/Virology
GW779439X 属于吡唑并吡啶类,是一种金黄色葡萄球菌 PASTA 激酶 Stk1抑制剂。它是一种AURKA 抑制剂,可通过 caspases 3/7 诱导细胞凋亡。
T4296 MTX-211

MTX 211

EGFR; PI3K Angiogenesis; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
MTX-211 是EGFR 和PI3K 的双重抑制剂,可用于癌症和其他疾病研究。
T9945 MNK8 

3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

STAT JAK/STAT signaling; Stem Cells
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) 是一种有效的STAT3抑制剂,降低STAT3与DNA 结合的能力,对肝癌细胞也有良好的生长抑制作用。
T33676 Niraxostat

Y 700,Y700,Y-700

Xanthine Oxidase Metabolism
Niraxostat (Y-700) 是作为黄嘌呤氧化酶抑制剂的异胞嘧啶衍生物之一。
T84322 N-[(4-methylphenyl)carbamothioyl]-2-nitrobenzamide

Others Others
N-[(4-methylphenyl)carbamothioyl]-2-nitrobenzamide 可用于 N-aryl-N'-(o-nitrobenzoyl)thiourea derivatives 的合成以及相关研究。
T38311 (S)-3-Thienylglycine

Others Others
(S)-3-Thienylglycine 是一种噻吩衍生物,可用于研究与噻吩衍生物相似结构的遗传毒性。
T2192 Indazole

Sodium Channel Membrane transporter/Ion channel
Indazole 又称benzpyrazole 或isoindazone,它的衍生物表现出广泛的生物活性,吲哚唑及其衍生物可用于癌症、神经系统疾病、心血管疾病、胃肠道疾病的研究
T1106 Afalanine

N-Acetyl-DL-phenylalanine,阿丙氨酸

Amino Acids and Derivatives Metabolism
Afalanine (N-Acetyl-DL-phenylalanine) 是抗抑郁药。
T9968 3-Piperidinyl(1-pyrrolidinyl)methanone HCl

Others Others
3-Piperidinyl(1-pyrrolidinyl)methanone hydrochloride 可用于合成 MCH-R1 拮抗剂 piperidin-4-yl-urea 衍生物。
T5388 2,5-PYRIDINEDICARBOXYLIC ACID

Others Others
2,5-PYRIDINEDICARBOXYLIC ACID 用于制备新的衍生物作为抗病毒剂。
T12612 (R)-Apremilast

R-阿普斯特,(R)-CC-10004

Others Others
(R)-Apremilast ((R)-CC-10004) 是一种 Apremilast 的异构体。
TP1711 5-Tamra-DRVYIHP

Others Others
5-Tamra-DRVYIHP 是一种含有用寡核苷酸标记的罗丹明衍生物的多肽。
T20324 Butyrophenone

苯丁酮,NSC8463,NSC 8463,NSC-8463

Others Others
Butyrophenone (NSC-8463) 是一种化合物。它的一些衍生物用于治疗各种精神疾病。
T67568 Fmoc-Met-OH

Fmoc-L-Met-OH

Fmoc-Met-OH (Fmoc-L-Met-OH) 是一种基于fmoc的程序合成的甲硫氨酸衍生物。
T9632 CDK9-IN-30

HIV Protease Microbiology/Virology; Proteases/Proteasome
CDK9-IN-30 是 Tat 肽衍生物之一,可抑制 HIV-1 长末端重复激活转录。
T9624 iron chloride hexahydrate

Others Others
iron chloride hexahydrate 促进了苯基酮衍生物的选择性羟基化和氯化反应,用于构建杂四元骨架。
T79830 B-Raf IN 16

Raf MAPK
B-Raf IN 16,一种 BRAF 抑制剂,属于环状亚氨基嘧啶衍生物,可用于研究癌症或肿瘤。
T9823 WAY-325398

Others Others
WAY-325398是一种呋喃衍生物。WAY-325398抑制破骨细胞形成,10μM 时抑制率为14.11%。
T9526 Polysorbate 20

Tween-20,吐温 20

Others Others
Polysorbate 20 (Tween-20) 是聚氧乙烯型非离子表面活性剂。
T21412 Ketorolac

Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular

COX Immunology/Inflammation; Neuroscience
Ketorolac (Acuvail) 是非甾体抗炎剂,是非选择性的COX 抑制剂,对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
T68127 Picenadol

LY-150720,LY150720,LY 150720

Others Others
Picenadol (LY 150720) 是N-甲基-4-苯基哌啶衍生物的外消旋混合物,具有激动剂 - 拮抗剂阿片性质。Picenadol  具有中枢镇痛活性。
T1731 TAME hydrochloride

NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐,Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride

Amino Acids and Derivatives; APC Cell Cycle/Checkpoint; Metabolism
TAME hydrochloride (Tos-Arg-OMe HCl) 是后期促进复合体(APC/C 或 APC)的抑制剂,可与 APC/C 结合并阻止其通过 Cdc20 和 Cdh1 活化,产生有丝分裂阻滞。它是一种 od 氨基酸衍生物。
T67792 BTA-188

Antiviral Immunology/Inflammation
BTA-188是一种新型的和具有口服活性的合成的苯并恶唑和苯并噻唑衍生物中有效的类似物 ,具有显著抗鼻病毒活性 。
T18905 6-TAMRA

6-羧基四甲基罗丹明,6-Carboxytetramethylrhodamine

Others Others
6-TAMRA (6-Carboxytetramethylrhodamine) 常用作制备生物偶联物的荧光团,尤其是用于免疫化学的荧光抗体剂抗生物素蛋白衍生物。
T20509 Lophine

2,4,5-Triphenylimidazole,2,4,5-三苯基咪唑,NSC 62790,NSC-62790,NSC62790

Others Others
Lophine (NSC-62790) 用于合成蛋白激酶抑制剂、钙拮抗剂、强心强心剂和抗肿瘤药物。 Lophine 衍生物作为体外化学发光活化剂用于检测自由基。
T0218 Biperiden

Bipariden,Akineton,KL 373,比哌立登,Biperidine

AChR Neuroscience
Biperiden (Bipariden) 是中枢 M1胆碱受体阻断剂,有抗帕金森症活性。
T38345 SQ609

Others Others
SQ609是从一个双哌啶衍生物库中选取的抗结核潜在药物。SQ609在体外小鼠巨噬细胞中具有显著的抗结核活性。
T14131 ADPS

N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt,ESPAS

Others Others
ADPS (N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt) 是新型 Trinder's 试剂,是一种高水溶性苯胺衍生品,普遍用于生化试验、诊断检测。
T12987 Spirodiclofen

BAJ-2740,螺螨酯

Parasite Microbiology/Virology
Spirodiclofen (BAJ-2740) 是选择性非系统性的杀螨剂,来自新的化学类特酮酸衍生物, 与目前市面上的杀螨剂无交叉耐药, 具有额外的杀虫性能。
T21551 2-hexyl-4-Pentynoic Acid

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
2-Hexyl-4-pentynoic acid 是一种丙戊酸 (VPA) 衍生物,可以抑制HDAC(IC50=13 µM) 和诱导HSP70。它可引起培养神经元的组蛋白高度乙酰化,防止谷氨酸诱导的兴奋性毒性,具有强大的神经保护作用。
T77674 3-Cyano-7-hydroxycoumarin

3-Cyanoumbelliferone

3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) 是一种巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂,Ki 为 2.9 μM。3-Cyano-7-hydroxycoumarin 属于香豆素衍生物,可被用作分子探针和荧光染料。
TNU0168 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine

Apoptosis Apoptosis
Nucleoside Derivatives - Fluoro-modified nucleosides, Arabino-nucleosides, 2’-Modified nucleosides; Drugs and Inhibitors; Anticancer agent; Impurity C of Clofarabine
T4469 Nemorubicin

Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星

Others Others
Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。
T8749 CS-B1628

2-(6-溴-5-甲基-2,4-二氧代-1,4-二氢噻吩并[2,3-D]嘧啶-3(2H) - 基)-,tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate,ACN-053859

Others Others
CS-B1628 (tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate) 可用于合成嘧啶衍生物,具有成为各种有机化合物(包括药物和农用化学品)起始材料的潜在用途。
TD0101 AQC

6-Aminoquinolyl-N-hydroxysccinimidyl carbamate

Others Others
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) 是一种高效液相色谱荧光检测氨基酸或蛋白质序列的试剂。它能够与一级和二级氨基酸反应生成荧光衍生物,在皮摩尔水平下能够检测氨基酸。
T31011 Coralyne chloride

Topoisomerase DNA Damage/DNA Repair
Coralyne chloride 是一种具有强抗癌活性的原小檗碱。它可用于制备 Coralyne 衍生物,是一种基于荧光 DNA 的分子整流剂,通过位点特异性插入构建成 DNA 双链体。它可作为一种拓扑异构酶 I 毒性分子,诱导拓扑异构酶 I 介导 DNA 裂解。
T0056 Oxeladin citrate

Others Others
Oxeladin citrate 是止咳剂,能够对各种病因引发咳嗽进行有效研究。
T11043 Dihydroergocristine mesylate

甲磺酸双氢麦角汀,DHEC (mesylate)

Beta Amyloid Neuroscience
Dihydroergocristine mesylate (DHEC (mesylate)) 是一种 γ-secretase (GSI) 的抑制剂,能够阿尔茨海默氏病淀粉样蛋白 β 肽 (amyloid-β) 的产生,与 γ-secretase 和 Nicastrin 结合的平衡解离常数 (Kd) 值分别为 25.7 nM 和 9.8 μM。

化合物

Thiazolidinone-Derivatives-1
Cat.No: T13145
Synonym:
Target: Others
Questiomycin A derivatives 18 TFA
Cat.No: T67717L
Synonym:
Target: Others
Questiomycin A derivatives 21
Cat.No: T67720
Synonym:
Target: Others
Questiomycin A derivatives 35 HCl
Cat.No: T77738L
Synonym: Phx-3 derivatives 35 HCl
Target: Others
Questiomycin A derivatives 24
Cat.No: T67723
Synonym:
Target: Others
Questiomycin A derivatives 22
Cat.No: T67721
Synonym:
Target: Others
Calcitriol Derivatives
Cat.No: T19226
Synonym:
Target: Others
Questiomycin A derivatives 13
Cat.No: T67712
Synonym:
Target: Others
Questiomycin A derivatives 12
Cat.No: T67711
Synonym:
Target: Others
Questiomycin A derivatives 14
Cat.No: T67713
Synonym:
Target: Others
Questiomycin A derivatives 20
Cat.No: T67719
Synonym:
Target: Others
Questiomycin A derivatives 27
Cat.No: T72086
Synonym:
Target: Others
GW779439X
Cat.No: T8866
Synonym:
Target: Apoptosis, Antibacterial, CDK, Aurora Kinase
MTX-211
Cat.No: T4296
Synonym: MTX 211
Target: EGFR, PI3K
MNK8 
Cat.No: T9945
Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione
Target: STAT
Niraxostat
Cat.No: T33676
Synonym: Y 700,Y700,Y-700
Target: Xanthine Oxidase
N-[(4-methylphenyl)carbamothioyl]-2-nitrobenzamide
Cat.No: T84322
Synonym:
Target: Others
(S)-3-Thienylglycine
Cat.No: T38311
Synonym:
Target: Others
Indazole
Cat.No: T2192
Synonym:
Target: Sodium Channel
Afalanine
Cat.No: T1106
Synonym: N-Acetyl-DL-phenylalanine,阿丙氨酸
Target: Amino Acids and Derivatives
3-Piperidinyl(1-pyrrolidinyl)methanone HCl
Cat.No: T9968
Synonym:
Target: Others
2,5-PYRIDINEDICARBOXYLIC ACID
Cat.No: T5388
Synonym:
Target: Others
(R)-Apremilast
Cat.No: T12612
Synonym: R-阿普斯特,(R)-CC-10004
Target: Others
5-Tamra-DRVYIHP
Cat.No: TP1711
Synonym:
Target: Others
Butyrophenone
Cat.No: T20324
Synonym: 苯丁酮,NSC8463,NSC 8463,NSC-8463
Target: Others
Fmoc-Met-OH
Cat.No: T67568
Synonym: Fmoc-L-Met-OH
Target:
CDK9-IN-30
Cat.No: T9632
Synonym:
Target: HIV Protease
iron chloride hexahydrate
Cat.No: T9624
Synonym:
Target: Others
B-Raf IN 16
Cat.No: T79830
Synonym:
Target: Raf
WAY-325398
Cat.No: T9823
Synonym:
Target: Others
Polysorbate 20
Cat.No: T9526
Synonym: Tween-20,吐温 20
Target: Others
Ketorolac
Cat.No: T21412
Synonym: Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular
Target: COX
Picenadol
Cat.No: T68127
Synonym: LY-150720,LY150720,LY 150720
Target: Others
TAME hydrochloride
Cat.No: T1731
Synonym: NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐,Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride
Target: Amino Acids and Derivatives, APC
BTA-188
Cat.No: T67792
Synonym:
Target: Antiviral
6-TAMRA
Cat.No: T18905
Synonym: 6-羧基四甲基罗丹明,6-Carboxytetramethylrhodamine
Target: Others
Lophine
Cat.No: T20509
Synonym: 2,4,5-Triphenylimidazole,2,4,5-三苯基咪唑,NSC 62790,NSC-62790,NSC62790
Target: Others
Biperiden
Cat.No: T0218
Synonym: Bipariden,Akineton,KL 373,比哌立登,Biperidine
Target: AChR
SQ609
Cat.No: T38345
Synonym:
Target: Others
ADPS
Cat.No: T14131
Synonym: N-Ethyl-N-(3-sulfopropyl)-3-methoxyaniline sodium salt,ESPAS
Target: Others
Spirodiclofen
Cat.No: T12987
Synonym: BAJ-2740,螺螨酯
Target: Parasite
2-hexyl-4-Pentynoic Acid
Cat.No: T21551
Synonym:
Target: HDAC
3-Cyano-7-hydroxycoumarin
Cat.No: T77674
Synonym: 3-Cyanoumbelliferone
Target:
2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine
Cat.No: TNU0168
Synonym:
Target: Apoptosis
Nemorubicin
Cat.No: T4469
Synonym: Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星
Target: Others
CS-B1628
Cat.No: T8749
Synonym: 2-(6-溴-5-甲基-2,4-二氧代-1,4-二氢噻吩并[2,3-D]嘧啶-3(2H) - 基)-,tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate,ACN-053859
Target: Others
AQC
Cat.No: TD0101
Synonym: 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
Target: Others
Coralyne chloride
Cat.No: T31011
Synonym:
Target: Topoisomerase
Oxeladin citrate
Cat.No: T0056
Synonym:
Target: Others
Dihydroergocristine mesylate
Cat.No: T11043
Synonym: 甲磺酸双氢麦角汀,DHEC (mesylate)
Target: Beta Amyloid
Cat. No. Product Name Target Signaling Pathways
T20003 Acridone

Antibacterial; ABC Membrane transporter/Ion channel; Microbiology/Virology
Acridone 具有抗菌、抗疟、抗病毒和抗肿瘤活性。它可诱导细胞凋亡,抑制 ABCG2 蛋白,并调节激素水平。
TN7020 Astragenol

Others Others
Astragenol 是合成黄芪醇衍生物的中间体。它的衍生物具有抗炎作用,可用于前列腺癌的研究。
T1346 1-Phenyl-1,2-ethanediol

Others Others
1-Phenyl-1,2-ethanediol 是 O-benzyl oxime ether 衍生物,用作杀虫剂。
T4795 Pimelic acid

Pileric acid,1,7-Heptanedioic acid,庚二酸,1,5-Pentanedicarboxylic acid

Others; Endogenous Metabolite Metabolism; Others
Pimelic acid (1,5-Pentanedicarboxylic acid) 的衍生物能够参与赖氨酸的生物合成。
TL0015 Pyromeconic acid

3-羟基-4氢-吡喃-4-酮,3-hydroxy-4H-pyran-4-one

Anti-infection Microbiology/Virology
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) 及其衍生物是核酸内切酶的有效抑制剂
T3758 2,6-Dimethoxybenzoic acid

Others; Endogenous Metabolite; Antifungal Metabolism; Microbiology/Virology; Others
2,6-Dimethoxybenzoic acid 是一种邻甲氧苯甲酸及其衍生物,抑制真菌和细菌。
TN7071 Ergosterol Acetate

Ergosta-5,7,22-trien-3-beta-yl acetate

Others Others
Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) 是来自红曲霉的 Ergosterol 的乙酸酯衍生物之一。
T9327 ω-Pentadecalactone

Cyclopentadecanolide,ω-十五内酯,Oxacyclohexadecan-2-one,Exaltolide,Pentadecanolide

Others Others
ω-Pentadecalactone (Exaltolide) 是香料成分,是一种香味结构组大环内酯和丙交酯衍生物的成员。
T4798 N-Acetyl-L-leucine

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-leucine 是内源性代谢产物的一种。
T2832 Isocorydine

Artabotrin,S-Isocorydine(+),异紫堇定,Luteanin,Uzokoridin,(+)-Isocorynoline

Others; Endogenous Metabolite Metabolism; Others
S-Isocorydine (Uzokoridin)(+) 是一种从美德罗克线虫 Dicranostigma leptopodum (Maxim.) Fedde 中分离得到,与阿霉素的结合具有消除肝细胞癌的潜力。
T4712 H-D-cis-Hyp-OH

顺式-4-羟基-D-脯氨酸,D-allo-Hydroxyproline,cis-4-Hydroxy-D-proline

Others; Endogenous Metabolite Metabolism; Others
H-D-cis-Hyp-OH (D-allo-Hydroxyproline) 是一种合成构象受限的 PNA 腺嘌呤单体的前体,能够用于 D-丙氨酸脱氢酶的特异性和动力学的研究。
TJS0338 4-Methylesculetin

4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭

Antioxidant; Glutathione Peroxidase Metabolism; oxidation-reduction
4-Methylesculetin (Methylesculetin) 是口服具有活力的天然香豆素衍生物,有抗氧化、抗炎特性。它可抑制myeloperoxidase 的特性,抑制 IL-6 的水平
T10388 Asparagusic acid

1,2-二噻戊环-4-羧酸,芦笋酸

Parasite Microbiology/Virology
Asparagusic acid 是芦笋植物中的一种含硫气味成分,是植物生长抑制剂,具有抗寄生虫作用。
TJS0405 Lucidin

NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine

Others Others
Lucidin (NSC-30546) 是茜草中的一种天然成分,可以诱导细菌和哺乳动物细胞的突变。
T4711 2,4-Dihydroxypyrimidine-5-carboxylic acid

脲嘧啶-5-羧酸,Isoorotic acid,Uracil-5-carboxylic acid

Others; Endogenous Metabolite Metabolism; Others
2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) 是内源性代谢产物的一种。
T2734 Sennoside B

番泻苷 B,番泻苷B

PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Sennoside B 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷。它可通过与 PDGF-BB 及其受体结合并下调 PDGFR-β 信号传导途径来抑制 PDGF 刺激的细胞增殖。
TNU0157 3’-O-Methyl guanosine

Endogenous Metabolite Metabolism
核苷衍生物 – 3’-改性核苷:该化合物属于核苷衍生物类,特点是在其3’位置上进行了化学修饰。这种修饰赋予了化合物特殊的生物学活性或增强了其原有功能,常见于药物研发及生物医学研究中。
TN1012 Febrifugine

IL Receptor; Anti-infection; Parasite Immunology/Inflammation; Microbiology/Virology
Febrifugine 是存在于常山的根和叶中的一种喹唑啉酮类生物碱,有抗疟活性。它是一种有效的抗球虫药,具有杀灭裂殖体的作用。
T4842 1H-pyrazole

1,2-Diazole,Pyrazole,吡唑

Others; Endogenous Metabolite Metabolism; Others
1H-pyrazole (1,2-Diazole) 是内源性代谢产物的一种。
TN1097 β-Boswellic acid

Beta-boswellic acid,β-乳香酸

Lipoxygenase; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
β-Boswellic acid (Beta-boswellic acid) 是从乳香的树胶脂中分离出来的一种天然产物。它是 5-脂氧合酶(5-LO) 产物形成的非还原型抑制剂,其直接与 5-LO 相互作用或阻断其易位。具有抗癌、抗肿瘤和抗高血脂活性。
T2981 Xanthoxylin

Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone

Others; Antifungal Microbiology/Virology; Others
Xanthoxylin (Brevifolin)e 是从Zanthoxylum simulans 中分离出来的是一种冰片和樟脑味化合物,有抗真菌和抗癫痫作用。
Fr16741 Oxindole

2-吲哚酮,板蓝根,Indolin-2-one

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Oxindole (Indolin-2-one) 是一种芳族杂环砌块,其衍生物是激酶抑制剂研究中的主要成分。
T1301 Guaiacol

O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

NF-κB; COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类,可抑制 LPS 刺激的COX-2表达和NF-κB 激活,具有抗炎活性。
T8274 3-Methyl-L-histidine

Endogenous Metabolite Metabolism
3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T4773 3-Ethoxy-3-oxopropanoic acid

Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯

Others; Endogenous Metabolite Metabolism; Others
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。
T5S2017 Ingenol

(-)-Ingenol,巨大戟二萜醇,巨大戟醇

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
Ingenol ((-)-Ingenol) 是一种PKC 激活剂,Ki 值为 30 μM,具有抗肿瘤活性。 从 Ingenol 酯中配制新的衍生物可能是开发新的先导化合物以重新激活潜伏 HIV 的创新方法。Ingenol mebutate 是治疗光化性角化病的有效方法。
TCS1372 Atraric acid

Phosphatase; Androgen Receptor Endocrinology/Hormones; Metabolism
Atraric acid 衍生物作为一种新的化学先导结构,用于作为 AR 拮抗剂的新型治疗化合物,可用于预防或治疗前列腺疾病。它以剂量依赖性方式抑制 PTP1B 活性,IC50 值为 51.5 uM,表明阿特拉酸具有治疗糖尿病的潜力。
TCS1772 Dehydroabietic acid

Dehydroabietate,脱氢松香酸

Antifection Microbiology/Virology
Dehydroabietic acid (Dehydroabietate) 是 EBV-EA 活化抑制剂。 它是食物衍生化合物,可通过降低血浆葡萄糖、胰岛素水平、血浆甘油三酯 (TG) 和肝 TG 水平来治疗肥胖相关疾病。它的衍生物在动物模型中表现出抗分泌和抗胃蛋白酶作用。
TL0005 3,5-O-Dicaffeoylquinic acid

Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid

Others Others
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) 能够改善由三甲基锡诱导的学习和记忆缺陷。
T4768 Diethyl oxalpropionate

草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE

Others; Endogenous Metabolite Metabolism; Others
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。
T2P2923 Stearic acid

硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid

Phosphatase; Endogenous Metabolite Metabolism
Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸,存在于许多动植物油脂中。
T1121 Podofilox

鬼臼毒素,Podophyllotoxin,(+)-Shikonin

Microtubule Associated; Topoisomerase Cytoskeletal Signaling; DNA Damage/DNA Repair
Podofilox ((+)-Shikonin) 是从八角莲中分离的一种木脂素,是微管组装和 DNA 拓扑异构酶 II 抑制剂。它对皮肤和粘膜有很强的刺激性,具有角质溶解作用,可用于治疗疣和角化病,具有潜在的抗肿瘤特性。
TN6909 Polyporusterone B

猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Others Others
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) 是一种三萜羧酸,从Polyporus umbellatusFries 中分离得到。它对自由基诱导的红细胞裂解 (溶血) 具有抑制作用。
T1183 Retinol

all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Others Others
Retinol (Vitamin A) 属于天然维生素,具有脂溶性。Retinol 在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。
T5S0018 Betulonic acid

路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Parasite; HSV Microbiology/Virology
Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物,具有抗肿瘤,抗炎,抗寄生虫和抗病毒的活性。
T4900 (±)-Methyl Jasmonate

(±)-茉莉酸甲酯,甲基茉莉酮酸酯,(±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate

Others; Endogenous Metabolite Metabolism; Others
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester) 是内源性代谢产物的一种。
T4848 Mandelic acid

acidomandelico,DL-Mandelic acid,扁桃酸

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。
T4880 L-Dihydroorotic acid

Others; Endogenous Metabolite Metabolism; Others
L-Dihydroorotic acid 是一种能够通过二氢乳清酶,能够逆水解产生的无环 L-脲基琥珀酸。
T3339 Sophoridine

5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine

Apoptosis; Topoisomerase Apoptosis; DNA Damage/DNA Repair
Sophoridine (Dihydro-5-episophocarpine) 是一种从豆科植物槐豆斜生植物的叶子中分离出来的喹喔啉生物碱。它是胰腺癌的候选药物,诱导细胞凋亡。
T3929 Kaurenoic acid

Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid

Others Others
Kaurenoic acid (kaurenoate) 是一种二萜,来源于 Sphagneticola trilobata 中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。
T37345 5,7-Dihydroxycoumarin

Antibacterial Microbiology/Virology
5,7-Dihydroxycoumarin 是分离自Macaranga triloba 花序的香豆素,具有抗菌活性。
T36914 2-Hydroxyanthraquinone

Others Others
2-Hydroxyanthraquinone 是一种天然产物,显示出抗肿瘤和免疫抑制活性。
T5S2343 Acetylshikonin

乙酰紫草素,Acetyl shikonin

Others; P450; AChE Metabolism; Neuroscience; Others
Acetylshikonin 来源于紫草根,具有抗癌、抗炎作用。它是一种 AChE 抑制剂,具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂,对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
T4858 4-​Hydroxyphenylpyruvic acid

4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid

Endogenous Metabolite Metabolism
4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物,是一种酶抑制剂。
TQ0208 SAH

SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸

Others; Endogenous Metabolite Metabolism; Others
SAH (S-Adenosylhomocysteine) 属于氨基酸衍生物,是腺苷和半胱氨酸合成的中间体。SAH 是一种 METTL3-METTL14 异二聚体复合物的抑制剂 (IC50=0.9 µM)。SAH 是多种代谢途径中的调节剂。
TN2028 p-Coumaryl alcohol

Others Others
p-Coumaryl alcohol derivatives have antioxidant activity.
T3S2016 Epoxylathyrol

Others Others
Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells.
T19515 Phosphocreatine dipotassium

Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium)

Others Others
Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.
TN6511 Tessaric acid

Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
TN3042 4-Hydroxycinnamamide

ATPase; EGFR; Potassium Channel; p38 MAPK; Calcium Channel; Sodium Channel; AMPK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
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天然产物

Acridone
Cat.No: T20003
Synonym:
Target: Antibacterial, ABC
Astragenol
Cat.No: TN7020
Synonym:
Target: Others
1-Phenyl-1,2-ethanediol
Cat.No: T1346
Synonym:
Target: Others
Pimelic acid
Cat.No: T4795
Synonym: Pileric acid,1,7-Heptanedioic acid,庚二酸,1,5-Pentanedicarboxylic acid
Target: Others, Endogenous Metabolite
Pyromeconic acid
Cat.No: TL0015
Synonym: 3-羟基-4氢-吡喃-4-酮,3-hydroxy-4H-pyran-4-one
Target: Anti-infection
2,6-Dimethoxybenzoic acid
Cat.No: T3758
Synonym:
Target: Others, Endogenous Metabolite, Antifungal
Ergosterol Acetate
Cat.No: TN7071
Synonym: Ergosta-5,7,22-trien-3-beta-yl acetate
Target: Others
ω-Pentadecalactone
Cat.No: T9327
Synonym: Cyclopentadecanolide,ω-十五内酯,Oxacyclohexadecan-2-one,Exaltolide,Pentadecanolide
Target: Others
N-Acetyl-L-leucine
Cat.No: T4798
Synonym:
Target: Others, Endogenous Metabolite
Isocorydine
Cat.No: T2832
Synonym: Artabotrin,S-Isocorydine(+),异紫堇定,Luteanin,Uzokoridin,(+)-Isocorynoline
Target: Others, Endogenous Metabolite
H-D-cis-Hyp-OH
Cat.No: T4712
Synonym: 顺式-4-羟基-D-脯氨酸,D-allo-Hydroxyproline,cis-4-Hydroxy-D-proline
Target: Others, Endogenous Metabolite
4-Methylesculetin
Cat.No: TJS0338
Synonym: 4-Methyl-6,7-dihydroxycoumarin,6,7-二羟基-4-甲基香豆素,Methylesculetin,4-甲基七叶亭
Target: Antioxidant, Glutathione Peroxidase
Asparagusic acid
Cat.No: T10388
Synonym: 1,2-二噻戊环-4-羧酸,芦笋酸
Target: Parasite
Lucidin
Cat.No: TJS0405
Synonym: NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine
Target: Others
2,4-Dihydroxypyrimidine-5-carboxylic acid
Cat.No: T4711
Synonym: 脲嘧啶-5-羧酸,Isoorotic acid,Uracil-5-carboxylic acid
Target: Others, Endogenous Metabolite
Sennoside B
Cat.No: T2734
Synonym: 番泻苷 B,番泻苷B
Target: PDGFR
3’-O-Methyl guanosine
Cat.No: TNU0157
Synonym:
Target: Endogenous Metabolite
Febrifugine
Cat.No: TN1012
Synonym:
Target: IL Receptor, Anti-infection, Parasite
1H-pyrazole
Cat.No: T4842
Synonym: 1,2-Diazole,Pyrazole,吡唑
Target: Others, Endogenous Metabolite
β-Boswellic acid
Cat.No: TN1097
Synonym: Beta-boswellic acid,β-乳香酸
Target: Lipoxygenase, DNA/RNA Synthesis
Xanthoxylin
Cat.No: T2981
Synonym: Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone
Target: Others, Antifungal
Oxindole
Cat.No: Fr16741
Synonym: 2-吲哚酮,板蓝根,Indolin-2-one
Target: Others, HIV Protease
Guaiacol
Cat.No: T1301
Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚
Target: NF-κB, COX, Endogenous Metabolite
3-Methyl-L-histidine
Cat.No: T8274
Synonym:
Target: Endogenous Metabolite
3-Ethoxy-3-oxopropanoic acid
Cat.No: T4773
Synonym: Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯
Target: Others, Endogenous Metabolite
Ingenol
Cat.No: T5S2017
Synonym: (-)-Ingenol,巨大戟二萜醇,巨大戟醇
Target: PKC
Atraric acid
Cat.No: TCS1372
Synonym:
Target: Phosphatase, Androgen Receptor
Dehydroabietic acid
Cat.No: TCS1772
Synonym: Dehydroabietate,脱氢松香酸
Target: Antifection
3,5-O-Dicaffeoylquinic acid
Cat.No: TL0005
Synonym: Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid
Target: Others
Diethyl oxalpropionate
Cat.No: T4768
Synonym: 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE
Target: Others, Endogenous Metabolite
Stearic acid
Cat.No: T2P2923
Synonym: 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid
Target: Phosphatase, Endogenous Metabolite
Podofilox
Cat.No: T1121
Synonym: 鬼臼毒素,Podophyllotoxin,(+)-Shikonin
Target: Microtubule Associated, Topoisomerase
Polyporusterone B
Cat.No: TN6909
Synonym: 猪苓酮B,(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one
Target: Others
Retinol
Cat.No: T1183
Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin
Target: Others
Betulonic acid
Cat.No: T5S0018
Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid
Target: Parasite, HSV
(±)-Methyl Jasmonate
Cat.No: T4900
Synonym: (±)-茉莉酸甲酯,甲基茉莉酮酸酯,(±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate
Target: Others, Endogenous Metabolite
Mandelic acid
Cat.No: T4848
Synonym: acidomandelico,DL-Mandelic acid,扁桃酸
Target: Others, Endogenous Metabolite, Antibacterial
L-Dihydroorotic acid
Cat.No: T4880
Synonym:
Target: Others, Endogenous Metabolite
Sophoridine
Cat.No: T3339
Synonym: 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine
Target: Apoptosis, Topoisomerase
Kaurenoic acid
Cat.No: T3929
Synonym: Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid
Target: Others
5,7-Dihydroxycoumarin
Cat.No: T37345
Synonym:
Target: Antibacterial
2-Hydroxyanthraquinone
Cat.No: T36914
Synonym:
Target: Others
Acetylshikonin
Cat.No: T5S2343
Synonym: 乙酰紫草素,Acetyl shikonin
Target: Others, P450, AChE
4-​Hydroxyphenylpyruvic acid
Cat.No: T4858
Synonym: 4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid
Target: Endogenous Metabolite
SAH
Cat.No: TQ0208
Synonym: SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸
Target: Others, Endogenous Metabolite
p-Coumaryl alcohol
Cat.No: TN2028
Synonym:
Target: Others
Epoxylathyrol
Cat.No: T3S2016
Synonym:
Target: Others
Phosphocreatine dipotassium
Cat.No: T19515
Synonym: Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium)
Target: Others
Tessaric acid
Cat.No: TN6511
Synonym:
Target:
4-Hydroxycinnamamide
Cat.No: TN3042
Synonym:
Target: ATPase, EGFR, Potassium Channel, p38 MAPK, Calcium Channel, Sodium Channel, AMPK
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Cat. No. Product Name Species Expression System
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...

Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPH-00916 ADH1B Protein, Human, Recombinant (His & SUMO)

ADH2,Alcohol dehydrogenase subunit beta,All-trans-retinol de...

Human E. coli
Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. ADH1B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli...
TMPH-03585 Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)

folP,Dihydropteroate synthase,DHPS,Dihydropteroate pyrophosp...

Staphylococcus haemolyticus E. coli
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q59919.
TMPH-00091 UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)

Flavonol 3-O-glucosyltransferase UGT71C1,UGT71C1,Flavonol 7-...

Arabidopsis thaliana P. pastoris (Yeast)
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resveratrol, curcumin, vanillin and etoposide. UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 56.4 kDa and the accession number is O82381.
TMPH-00090 UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)

Flavonol 7-O-beta-glucosyltransferase UGT71C1,UGT71C1,Flavon...

Arabidopsis thaliana E. coli
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resveratrol, curcumin, vanillin and etoposide. UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 59.4 kDa and the accession number is O82381.
TMPH-00110 UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Probable hydroquinone glucosyltransferase,Arbutin synthase,U...

Arabidopsis thaliana E. coli
Bifunctional O-glycosyltransferase and N-glycosyltransferase that can detoxify xenobiotics. Possesses high activity to metabolize the persistent pollutants 2,4,5-trichlorophenol (TCP) and 3,4-dichloroaniline (DCA). Also active on benzoates and benzoate derivatives in vitro. UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q9M156.
TMPY-03617 GMPR Protein, Human, Recombinant (His)

GMPR1,guanosine monophosphate reductase

Human E. coli
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPK-00150 FOLR1 Protein, Human, Recombinant (His & Avi)

Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...

Human HEK293 Cells
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t...
TMPY-02133 Carbonic Anhydrase VB Protein, Human, Recombinant (His)

carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962

Human E. coli
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process...
TMPJ-00731 Carbonic Anhydrase 1 Protein, Human, Recombinant (His)

Carbonic Anhydrase B,Carbonate Dehydratase I,CA-I,Carbonic A...

Human E. coli
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonam...
TMPY-03406 NMNAT1 Protein, Human, Recombinant (His)

PNAT1,LCA9,nicotinamide nucleotide adenylyltransferase 1,NMN...

Human Baculovirus Insect Cells
NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to protect against axonal degeneration following mechanical or toxic insults. The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT enz...
TMPY-01877 CA5A Protein, Human, Recombinant (His)

CA5,GS1-21A4.1,CA5AD,carbonic anhydrase VA, mitochondrial,CA...

Human E. coli
Carbonic anhydrase 5A, mitochondrial, also known as Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA and CA5A, is a member of thealpha-carbonic anhydrase family. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospi...
TMPY-03849 NUDT5 Protein, Human, Recombinant (His)

hYSAH1,YSAH1,nudix (nucleoside diphosphate linked moiety X)-...

Human E. coli
NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates. ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulates the levels of important signaling nucleotides and their metabolites. It is widely expressed in the liver, skin, and other tissues. NUDT5 functions as a MutT...
TMPY-01878 L-FABP Protein, Human, Recombinant (His)

fatty acid binding protein 1, liver,FABPL,L-FABP

Human E. coli
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is t...
TMPY-02552 Adenylosuccinate Lyase Protein, Human, Recombinant (His)

ASL,adenylosuccinate lyase,ASASE,AMPS

Human E. coli
Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotide...
TMPY-02803 IDO2 Protein, Human, Recombinant (His)

indoleamine 2,3-dioxygenase 2,INDOL1

Human E. coli
IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of tryptophan and other indole derivatives to kynurenines. In addition to classic IDO (IDO1), a new variant, IDO2, has recently been described. IDO2 is expressed in the liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. IDO is widely distributed in human ti...
TMPY-01761 Carbonic Anhydrase 3 Protein, Human, Recombinant (His)

carbonic anhydrase III,CAIII,Car3

Human E. coli
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases (CAs) form a family of enzymes that catalyze the rapid conversion of carbon dioxide and water to bicarbonate an...

重组蛋白

FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293 Cells
ADH1B Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00916
Species: Human
Expression System: E. coli
Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)
Cat.No: TMPH-03585
Species: Staphylococcus haemolyticus
Expression System: E. coli
UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)
Cat.No: TMPH-00091
Species: Arabidopsis thaliana
Expression System: P. pastoris (Yeast)
UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)
Cat.No: TMPH-00090
Species: Arabidopsis thaliana
Expression System: E. coli
UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Cat.No: TMPH-00110
Species: Arabidopsis thaliana
Expression System: E. coli
GMPR Protein, Human, Recombinant (His)
Cat.No: TMPY-03617
Species: Human
Expression System: E. coli
FOLR1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00150
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
Cat.No: TMPY-02133
Species: Human
Expression System: E. coli
Carbonic Anhydrase 1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00731
Species: Human
Expression System: E. coli
NMNAT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03406
Species: Human
Expression System: Baculovirus Insect Cells
CA5A Protein, Human, Recombinant (His)
Cat.No: TMPY-01877
Species: Human
Expression System: E. coli
NUDT5 Protein, Human, Recombinant (His)
Cat.No: TMPY-03849
Species: Human
Expression System: E. coli
L-FABP Protein, Human, Recombinant (His)
Cat.No: TMPY-01878
Species: Human
Expression System: E. coli
Adenylosuccinate Lyase Protein, Human, Recombinant (His)
Cat.No: TMPY-02552
Species: Human
Expression System: E. coli
IDO2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02803
Species: Human
Expression System: E. coli
Carbonic Anhydrase 3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01761
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMIH-0424 Pentoxyfylline-d6

Pentoxyfylline-d6 是 Pentoxyfylline 的氘代化合物。Pentoxyfylline 的 CAS 号为 。Questiomycin A derivatives 20 是一种Questiomycin A衍生物。
TMIH-0290 Ketorolac-d5-P1

Ketorolac-d5-P1 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂,是非选择性的COX抑制剂,对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIH-0291 Ketorolac-d5-P2

Ketorolac-d5-P2 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂,是非选择性的COX抑制剂,对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMID-0303 Vitamin A-d4

Retinol-d4

Vitamin A-d4 是 Vitamin A 的氘代化合物。Vitamin A 的 CAS 号为 68-26-8。Retinol 及其衍生物,在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。
TMID-0178 Stearic acid-18,18,18-d3

Stearic acid-18,18,18-d3 是 Stearic acid 的氘代化合物。Stearic acid 的 CAS 号为 57-11-4。Stearic acid是长链饱和脂肪酸,存在于许多动植物油脂中。
TMID-0056 (±)-Mandelic-2,3,4,5,6-d5 Acid

(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。

同位素标记化合物

Pentoxyfylline-d6
Cat.No: TMIH-0424
Synonym:
Target:
Ketorolac-d5-P1
Cat.No: TMIH-0290
Synonym:
Target:
Ketorolac-d5-P2
Cat.No: TMIH-0291
Synonym:
Target:
Vitamin A-d4
Cat.No: TMID-0303
Synonym: Retinol-d4
Target:
Stearic acid-18,18,18-d3
Cat.No: TMID-0178
Synonym:
Target:
(±)-Mandelic-2,3,4,5,6-d5 Acid
Cat.No: TMID-0056
Synonym:
Target:
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