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Selenomethionine

Name: Selenomethionine
Brand: TargetMol
SKU: T1658
Price: 148 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.95%

货号 T1658Cas号 1464-42-2

别名 Seleno-DL-methionine, DL-硒代蛋氨酸, DL-Selenomethionine

Selenomethionine (Seleno-DL-methionine) 是一种硒代氨基酸，是蛋氨酸的硒类似物。它具有作为植物代谢物的作用。它是硒代蛋氨酸和硒代氨基酸的成员。

Selenomethionine

一键复制产品信息

很棒

纯度: 99.95%

货号 T1658 别名 Seleno-DL-methionine, DL-硒代蛋氨酸, DL-SelenomethionineCas号 1464-42-2

Selenomethionine (Seleno-DL-methionine) 是一种硒代氨基酸，是蛋氨酸的硒类似物。它具有作为植物代谢物的作用。它是硒代蛋氨酸和硒代氨基酸的成员。

规格	价格	库存
25 mg	¥ 148	现货
50 mg	¥ 257	现货
100 mg	¥ 463	现货
200 mg	¥ 697	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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纯度: 99.95%

颜色: 白色

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COA LCMS HNMR 产品操作手册

产品介绍

Selenomethionine AI Summary

Selenomethionine exhibits a diverse range of bioactivities, demonstrating notable inhibitory effects across several targets. It functions as a modulator of Lamin A splicing with a potency of 631.0 nM and as an inhibitor of Aldehyde Dehydrogenase 1 (ALDH1A1) at 39810.7 nM. It also inhibits Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) with a potency of 50118.7 nM and Histone Lysine Methyltransferase G9a at 17782.8 nM. Additionally, Selenomethionine is an inhibitor of the malarial parasite plastid at 1694.4 nM and shows inhibitory effects against Trypanosoma Brucei at 7943.3 nM. It significantly inhibits Plasmodium falciparum (3D7) proliferation with a potency of 43.2 nM, Plasmodium falciparum (DD2) with potencies of 6.9 nM and 153.4 nM in different assays, and Plasmodium falciparum (HB3) at 27282.4 nM. In terms of antiviral activities, Selenomethionine inhibits SARS-CoV-2 induced cytotoxicity in Caco-2 cells at 10 µM after 48 hours with an inhibition rate of 9.25%. It also displays inhibition of the SARS-CoV-2 3CL-Pro protease by 9.2% at a 20 µM concentration based on a FRET assay. Additionally, the compound inhibits SARS-CoV-2 induced cytotoxicity in VERO-6 cells at 10 µM concentration after 48 hours of exposure to 0.01 MOI of the virus, with an observed inhibition percentage of 0.02%..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methionine with no effects on protein structure and function, providing a mechanism for reversible Se storage in organs and tissues.
别名	Seleno-DL-methionine, DL-硒代蛋氨酸, DL-Selenomethionine

化学信息

分子量	196.11
分子式	C₅H₁₁NO₂Se
CAS No.	1464-42-2
Smiles	C(C(O)=O)(CC[Se]C)N
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: < 1.96 mg/mL (10 mM, insoluble or slightly soluble)

H2O: 11.9 mg/mL (60.68 mM), Sonication is recommended.

溶液配制表

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	5.0992 mL	25.4959 mL	50.9918 mL	254.9590 mL
5 mM	1.0198 mL	5.0992 mL	10.1984 mL	50.9918 mL
10 mM	0.5099 mL	2.5496 mL	5.0992 mL	25.4959 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.2550 mL	1.2748 mL	2.5496 mL	12.7479 mL
50 mM	0.1020 mL	0.5099 mL	1.0198 mL	5.0992 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Selenomethionine EndogenousMetabolite Endogenous Metabolite Autophagy AminoAcidsandDerivatives Amino Acids and Derivatives

Selenomethionine

Selenomethionine