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Search Results for " copper "

102

抑制剂 & 化合物

10

天然产物

1

化合物库

1

TargetMol 试剂盒

22

重组蛋白

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Cat. No. Product Name
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究

化合物库

铜死亡化合物库
Cat.No: L8710
Compounds: 400
Cat. No. Product Name Form Specificity Of Inhibition
C0050 BCA Protein Quantification Kit

BCA蛋白浓度测定试剂盒

Solution in bottle

TargetMol 试剂盒

BCA蛋白浓度测定试剂盒
Cat.No: C0050
Cat. No. Product Name Target Signaling Pathways
T31008 Copper probe CF4

Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob

Copper probe CF4 (Copper fluor CF4) 是一种荧光铜探针,可用于研究结肠癌。
T1254 Chlorophyllin sodium copper salt

Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6

Others Others
Chlorophyllin sodium copper salt (Chlorophyllin coppered trisodium salt) 是一种由 Chlorophyll 衍生的铜钠盐的半合成混合物,常用作食品添加剂。
T8422 DIETHYLDITHIOCARBAMIC ACID COPPER SALT

Cupric diethyldithiocarbamate

Others Others
DIETHYLDITHIOCARBAMIC ACID COPPER SALT 是一种可用于各种金属、蛋白质和酶实验的螯合剂,也可作为络合剂合成包括杂环化合物在内的各种有机化合物,以及用作铜死亡的诱导剂。
TP1158 Copper tripeptide

[N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu

Others; Endogenous Metabolite Metabolism; Others
Copper tripeptide (GHK-Cu) 是天然存在的三肽,首先从人血浆中分离,但也能够在唾液和尿液中发现。它能够提高成纤维细胞中胶原蛋白,弹性蛋白,蛋白多糖和糖胺聚糖中信使 RNA 的产生。在伤口愈合期间,它能够通过蛋白水解从现有的细胞外蛋白质中除去,并且用作炎性和内皮细胞的化学引诱物。它是皮肤再生中多种细胞途径的天然调节剂。
T12953 Sodium copper chlorophyllin B

Influenza Virus; HIV Protease Microbiology/Virology; Proteases/Proteasome
Sodium copper chlorophyllin B 对流感病毒和HIV 有抗病毒活性,IC50s 值都是 50 到 100 μM。
T65090 Copper(II) gluconate

Others Others
Copper(II) gluconate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65090,CAS号为 527-09-3。
T81404 Prezatide copper

Bisprezatide copper,PC 1020,Iamin

Others Others
Prezatide Copper(亦称Iamin)具有促进伤口愈合的多重特性,且用于抑制脱发。
T60191 Cuprous iodide

Iodocopper,Copper (I) iodide

Antibiotic Microbiology/Virology
Cuprous iodide (Iodocopper) 是一种抗菌化合物。
T20213 Copper oxychloride

Blitox,Basic copper chloride,Blitox 50,Agrizan,Areecop

Others Others
Copper oxychloride is an agent of fungicide.
T67981 Copper histidine

Others Others
Copper histidine 抑制了Ctr1介导的奥沙利铂在体外的细胞摄取,而不会改变奥沙利铂在体内DRG 组织中的铂或神经毒性的积累。Copper histidine 通过口服治疗 Menkes 疾病。
T65167 EDTA copper(II) disodium salt

Antibiotic Microbiology/Virology
EDTA copper(II) disodium salt 是一种金属螯合剂,具有抗菌、抗炎、抗氧化活性,可减缓金属离子造成的损伤,可维持蛋白纯化过程中的渗透压,可用于研究神经系统疾病。
T82681 Copper tripeptide-3

AHK-Cu

AHK-Cu 是一种生物活性肽,具促进毛发生长功能,已作为化妆品成分使用。
T6170 Elesclomol

伊利司莫,STA-4783

Apoptosis; HSP; Reactive Oxygen Species Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
Elesclomol (STA-4783) 是一种氧化应激诱导剂,也是一种高度亲脂性的铜离子载体。Elesclomol 可以诱导肿瘤细胞凋亡,用于铜死亡相关研究。Elesclomol 还可以抑制 FDX1 介导的 Fe-S 簇生物合成。
T21876 DC_AC50

Apoptosis; Others Apoptosis; Others
DC_AC50 是一种 Atox 和 CCS 的双抑制剂,是一种抑制细胞内铜伴侣作为减少/预防获得性化疗耐药性的手段。它与 Atox1 和 CCS 结合并减少癌细胞增殖和肿瘤生长。
T14667 BLT-1

Others; HCV Protease Microbiology/Virology; Others; Proteases/Proteasome
BLT-1 是一种氨基硫脲铜螯合剂,是一种选择性清除受体 B1 型 (SR-BI) 抑制剂,抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T40996 Coppersensor 1

Coppersensor 1,CS1

Others Others
Coppersensor 1 (CS1) 是一种基于硼二吡咯亚甲基的荧光传感器,用于选择性和灵敏地检测生物样品中的铜 (I) 离子 (Cu + )。 Coppersensor 1 可以使用任何类型的荧光显微镜进行成像,包括落射荧光、共焦和多光子。
T5965 Ditiocarb sodium

Sodium diethyldithiocarbamate,二乙基二硫代氨基甲酸钠

HIV Protease Microbiology/Virology; Proteases/Proteasome
Ditiocarb sodium (Sodium diethyldithiocarbamate) 是一种铜胶结率的促进剂。它可降低HIV 感染。
T34956 Triplin

Others Others
Triplin 是铜离子的螯合剂。 Triplin 影响铜离子从 ATX1 到 RAN1 的传输。
T31907 Gamma-Methylleucine

L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid

Others Others
Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) 是铜催化的不对称迈克尔反应的辅助剂。
T15069 DBCO-PEG4-Biotin

ADIBO-NH-PEG2-Biotin

Others Others
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) 是一种 azadibenzocyclooctyne-biotin 衍生物,含有生物素基团和 4 个 PEG。DBCO-PEG4-Biotin 是一种用途广泛的生物素酰化试剂,能通过无铜催化烷基叠氮化反应 (SPAAC) 将生物素的一部分引入叠氮标记的生物分子中。
T21300 Trientine-2HCl

Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien

Others Others
Trientine-2HCl (Trien) 是一种螯合剂,通过结合和去除体内的铜来治疗威尔逊氏病。曲恩汀还可用作肝豆状核变性中铜的螯合剂,环氧树脂的稳定剂,等电聚焦的两性电解质。
T2229 Tetraethylenepentamine Pentahydrochloride

Others Others
Tetraethylenepentamine Pentahydrochloride 是一种高亲和力的铜和锌螯合剂。
T33631 Neocuproine

Neocuproin

Others Others
Neocuproine 是一种铜 (I) 螯合剂,可增强电场刺激引起的输精管收缩的嘌呤能成分,常被用作配位试剂和铜离子检测剂。Neocuproine 与铜离子形成稳定的络合物,并可在某些化学反应和分析方法中起到催化作用。Neocuproine 作为铁和钴上的氧化还原活性配体平台,对NSC34细胞氧化损伤的保护作用。
T0876 Clioquinol

Chinoform,Iodochlorhydroxyquin,氯碘羟喹

Mitophagy; Antibiotic; Autophagy; Antifungal Autophagy; Microbiology/Virology
Clioquinol (Iodochlorhydroxyquin) 是一种局部抗真菌药,具有抗肿瘤活性。它作为口服抗菌剂,可研究腹泻和皮肤感染。
T65013 Cuprizone

Others Others
Cuprizone 是一种铜螯合剂。Cuprizone 可用于诱导小鼠精神分裂症。Cuprizone 可诱导少突胶质细胞死亡,诱导脱髓鞘反应。
T1732 Semicarbazide hydrochloride

盐酸氨基脲,Aminourea hydrochloride

Others; Antibiotic Microbiology/Virology; Others
Semicarbazide hydrochloride 是一种尿素衍生物,能够与细胞中的铜或铁结合,产生抗病毒、抗感染和抗肿瘤作用。
T7086 Tris(benzyltriazolylmethyl)amine

三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA

Others Others
Tris(benzyltriazolylmethyl)amine (TBTA) 是一种能作为生化工具的配体,可用于标记蛋白质和酶。
T77948 Tri-GalNAc-DBCO

PROTACs PROTAC
Tri-GalNAc-DBCO是一种PIP-GalNAc 偶联物,通过无铜菌株促进的叠氮化物-炔烃环加成与非特异性标记抗体上的叠氮化物偶联,可结合ASGPR以驱动蛋白质下调和靶向蛋白质降解的化合物。
T83971L LCC-12 FA

Antiviral; Antibacterial Immunology/Inflammation; Microbiology/Virology
LCC-12 FA 是一种由二甲双胍组成的二聚体,通过靶向线粒体铜 (ii) 从而诱导 NAD(H) 池减少。LCC-12 FA 可减少细菌和病毒感染小鼠模型中的炎症,可用于研究代谢疾病。
T15076 DBCO-S-S-PEG3-biotin

生物素-PEG3-二硫-DBCO

Others; PROTAC Linker Others; PROTAC
DBCO-S-S-PEG3-biotin 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
T60278 Tyrosinase-IN-2

Tyrosinase Proteases/Proteasome
Tyrosinase-IN-2 (compound 67) 是一种有效的酪氨酸酶抑制剂。酪氨酸酶是一种含铜金属酶,负责黑色素生物合成和酶促褐变中的限速催化步骤。Tyrosinase-IN-2 具有研究皮肤美白剂和食品防腐剂的潜力。
T50049 4-Methylhistamine hydrochloride

Others Others
4-Methylhistamine hydrochloride 已被证明能抑制铜依赖性酶如酪氨酸酶和多巴胺β-羟化酶的活性,还被证明可以调节参与细胞周期调节和凋亡的基因的表达。
T0983L DL-Penicillamine

3-Sulfanylvaline,DL-青霉胺

Antibiotic Microbiology/Virology
DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂,推荐用于去除威尔逊病患者体内多余的铜。 它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
T31971 Glycyllysine

Gly-lys,Glycyl-L-lysine

Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.
T71885 Sodium 2-mercaptobenzothiazole

Others Others
Sodium 2-mercaptobenzothiazole is the sodium salt of mercaptobenzothiazole, and is used as a copper corrosion inhibitor.
T40794 HEPPSO

Others Others
HEPPSO is a zwitterionic buffer with a working pH range of 7.1-8.5. It exhibits strong copper(II) binding capability and a pK value of 7.84 at a concentration of 2.0 mM.
T36499 CuATSM

Others Others
The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic lateral sclerosis (ALS). Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that has traditionally been used in cellular imaging experiments to selectively label hypoxic tissue via its susceptibility ...
T40792 Cu(II)GTSM

Others Others
Cu(II)GTSM, a cell-permeable copper-complex, effectively inhibits GSK3β and shows inhibitory effects against Amyloid-β oligomers (AβOs) while reducing tau phosphorylation. Additionally, Cu(II)GTSM decreases the abundance of Amyloid-β trimers. With its potential as an anticancer and antimicrobial agent, Cu(II)GTSM exhibits promising therapeutic capabilities.
T19974 Propargyl-PEG3-azide

Propargyl-PEG3-amine

Others Others
Propargyl-PEG3-amine is a PEG derivative containing a propargyl group and an amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
T80934 Trisulfo-Cy5.5-Alkyne

Trisulfo-Cy5.5-Alkyne 是近红外(NIR)荧光染料,含有叠氮基团,能参与铜催化的 Click 化学反应。
T11317 FPA-124

Others Others
FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis. FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM.
T21356 4-(Trifluoromethyl)phenylboronic acid

Others Others
4-(Trifluoromethyl)benzeneboronic acid is used to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.
T15066 DBCO-NHS ester 2

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].
T29840 Alcian blue

Alcian blue is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.
T30662 C.I. 74240

NSC 324570,NSC-324570,NSC324570

C.I. 74240 is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo.
T80933 Trisulfo-Cy5-Alkyne

Trisulfo-Cy5-Alkyne是一种含有叠氮基团的点击化学试剂,可用于铜催化的Click化学反应,并兼具近红外(NIR)荧光染料的特性。
T61460 Tyrosinase-IN-3

Others Others
Tyrosinase-IN-3 (compound 54) is a powerful tyrosinase inhibitor, an enzyme involved in the key catalytic step of melanin biosynthesis and enzymatic browning. As a copper-containing metalloenzyme, tyrosinase plays a crucial role in these processes. The compound shows promise for studying skin whitening agents and food preservatives [1].
T20118 L-Penicillamine

Others Others
L-Penicillamine is a medication primarily. It is used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and lead poisoning.
T20946 Bismuth oxide

Bismuth sesquioxide,Bismuth trioxide,Bismutum-oxydatum,Bismuthous oxide

Others Others
Bismuth(III) oxide is a common starting point for bismuth chemistry. It is usually obtained as a by-product of the smelting of copper and lead ores. Bismuth trioxide is commonly used as a replacement of red lead to produce the “Dragon's eggs” effect in fi
T69149 L2-b

Others Others
L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.

化合物

Copper probe CF4
Cat.No: T31008
Synonym: Copper probe CF-4,Copper probe CF 4,Copper fluor CF4,CF4 prob
Target:
Chlorophyllin sodium copper salt
Cat.No: T1254
Synonym: Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6
Target: Others
DIETHYLDITHIOCARBAMIC ACID COPPER SALT
Cat.No: T8422
Synonym: Cupric diethyldithiocarbamate
Target: Others
Copper tripeptide
Cat.No: TP1158
Synonym: [N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu
Target: Others, Endogenous Metabolite
Sodium copper chlorophyllin B
Cat.No: T12953
Synonym:
Target: Influenza Virus, HIV Protease
Copper(II) gluconate
Cat.No: T65090
Synonym:
Target: Others
Prezatide copper
Cat.No: T81404
Synonym: Bisprezatide copper,PC 1020,Iamin
Target: Others
Cuprous iodide
Cat.No: T60191
Synonym: Iodocopper,Copper (I) iodide
Target: Antibiotic
Copper oxychloride
Cat.No: T20213
Synonym: Blitox,Basic copper chloride,Blitox 50,Agrizan,Areecop
Target: Others
Copper histidine
Cat.No: T67981
Synonym:
Target: Others
EDTA copper(II) disodium salt
Cat.No: T65167
Synonym:
Target: Antibiotic
Copper tripeptide-3
Cat.No: T82681
Synonym: AHK-Cu
Target:
Elesclomol
Cat.No: T6170
Synonym: 伊利司莫,STA-4783
Target: Apoptosis, HSP, Reactive Oxygen Species
DC_AC50
Cat.No: T21876
Synonym:
Target: Apoptosis, Others
BLT-1
Cat.No: T14667
Synonym:
Target: Others, HCV Protease
Coppersensor 1
Cat.No: T40996
Synonym: Coppersensor 1,CS1
Target: Others
Ditiocarb sodium
Cat.No: T5965
Synonym: Sodium diethyldithiocarbamate,二乙基二硫代氨基甲酸钠
Target: HIV Protease
Triplin
Cat.No: T34956
Synonym:
Target: Others
Gamma-Methylleucine
Cat.No: T31907
Synonym: L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid
Target: Others
DBCO-PEG4-Biotin
Cat.No: T15069
Synonym: ADIBO-NH-PEG2-Biotin
Target: Others
Trientine-2HCl
Cat.No: T21300
Synonym: Triethylenetetramine,Trientine HCl,Trientine,盐酸三乙烯四胺,Triethylene tetramine,TETA,Trien
Target: Others
Tetraethylenepentamine Pentahydrochloride
Cat.No: T2229
Synonym:
Target: Others
Neocuproine
Cat.No: T33631
Synonym: Neocuproin
Target: Others
Clioquinol
Cat.No: T0876
Synonym: Chinoform,Iodochlorhydroxyquin,氯碘羟喹
Target: Mitophagy, Antibiotic, Autophagy, Antifungal
Cuprizone
Cat.No: T65013
Synonym:
Target: Others
Semicarbazide hydrochloride
Cat.No: T1732
Synonym: 盐酸氨基脲,Aminourea hydrochloride
Target: Others, Antibiotic
Tris(benzyltriazolylmethyl)amine
Cat.No: T7086
Synonym: 三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA
Target: Others
Tri-GalNAc-DBCO
Cat.No: T77948
Synonym:
Target: PROTACs
LCC-12 FA
Cat.No: T83971L
Synonym:
Target: Antiviral, Antibacterial
DBCO-S-S-PEG3-biotin
Cat.No: T15076
Synonym: 生物素-PEG3-二硫-DBCO
Target: Others, PROTAC Linker
Tyrosinase-IN-2
Cat.No: T60278
Synonym:
Target: Tyrosinase
4-Methylhistamine hydrochloride
Cat.No: T50049
Synonym:
Target: Others
DL-Penicillamine
Cat.No: T0983L
Synonym: 3-Sulfanylvaline,DL-青霉胺
Target: Antibiotic
Glycyllysine
Cat.No: T31971
Synonym: Gly-lys,Glycyl-L-lysine
Target:
Sodium 2-mercaptobenzothiazole
Cat.No: T71885
Synonym:
Target: Others
HEPPSO
Cat.No: T40794
Synonym:
Target: Others
CuATSM
Cat.No: T36499
Synonym:
Target: Others
Cu(II)GTSM
Cat.No: T40792
Synonym:
Target: Others
Propargyl-PEG3-azide
Cat.No: T19974
Synonym: Propargyl-PEG3-amine
Target: Others
Trisulfo-Cy5.5-Alkyne
Cat.No: T80934
Synonym:
Target:
FPA-124
Cat.No: T11317
Synonym:
Target: Others
4-(Trifluoromethyl)phenylboronic acid
Cat.No: T21356
Synonym:
Target: Others
DBCO-NHS ester 2
Cat.No: T15066
Synonym:
Target: Others, ADC Linker
Alcian blue
Cat.No: T29840
Synonym:
Target:
C.I. 74240
Cat.No: T30662
Synonym: NSC 324570,NSC-324570,NSC324570
Target:
Trisulfo-Cy5-Alkyne
Cat.No: T80933
Synonym:
Target:
Tyrosinase-IN-3
Cat.No: T61460
Synonym:
Target: Others
L-Penicillamine
Cat.No: T20118
Synonym:
Target: Others
Bismuth oxide
Cat.No: T20946
Synonym: Bismuth sesquioxide,Bismuth trioxide,Bismutum-oxydatum,Bismuthous oxide
Target: Others
L2-b
Cat.No: T69149
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
Fr12596 3-Acetylcoumarin

Others Others
3-Acetylcoumarin 作为室温下铜催化 CN 偶联反应的实用配体。它具有神经保护和杀螨特性。
T0983 Penicillamine

青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Antibiotic Microbiology/Virology
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。
TN5672 Puerol A

Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.
T82956 Asparenyldiol

Asparenydiol

Asparenyldiol(Asparenydiol)为一类抗氧化剂且兼具点击化学试剂功能。该化合物含Alkyne基团,能够通过CuAAc与含Azide基团的分子发生反应。
T76129 Hemocyanin

Others Others
Hemocyanin是一种含铜的大分子呼吸蛋白,扮演着重要的非特异性先天免疫防御分子角色,具备酚氧化酶、抗病毒、抗菌、溶血及抗肿瘤活性。
TN2219 Sophoraisoflavone A

鲁冰花,砂生槐异黄酮 A

MRP; Antifection Immunology/Inflammation; Microbiology/Virology
Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibitory effects on copper-induced prot
T81168 Shishijimicin C

Shishijimicin C 是由子囊菌 Didemnum proliferum 分离得到的一种新型抗肿瘤剂,具有显著的细胞毒性和抗肿瘤活性。作为点击化学试剂,Shishijimicin C 含有Alkyne基团,能够通过铜催化的叠氮-炔环加成反应(CuAAc)与含Azide基团的分子反应。
T81170 Shishijimicin A

Shishijimicin A是一款从子囊菌Didemnum proliferum中分离出的新型抗肿瘤剂,具备突出的细胞毒性及抗肿瘤活性。作为点击化学试剂,Shishijimicin A内含Alkyne基团,能够与含Azide基团的分子通过铜催化的叠氮-炔环加成反应(CuAAc)进行作用。
T81169 Shishijimicin B

Shishijimicin B为活性的烯二炔类化合物,具有强烈的细胞毒性,IC50值介于2.0 - 3.3 nM。此化合物表现出抗肿瘤活性,常用于癌症研究中。作为点击化学试剂,Shishijimicin B内含Alkyne基团,能通过含Azide基团的分子在铜催化下发生(CuAAc)反应。
T81958 Lacto-N-neodifucohexaose II

LNnDFH II

Lacto-N-neodifucohexaose II(Compd 9),一种关键的人乳四糖衍生物,为点击化学反应试剂。该化合物含 Azide 基团,适用于铜催化叠氮-炔环加成反应(CuAAc),与含 Alkyne 基团的分子反应。同时,它也能与含 DBCO 或 BCN 基团的分子,进行菌株促进的炔-叠氮环加成反应(SPAAC)。

天然产物

3-Acetylcoumarin
Cat.No: Fr12596
Synonym:
Target: Others
Penicillamine
Cat.No: T0983
Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine
Target: Antibiotic
Puerol A
Cat.No: TN5672
Synonym:
Target:
Asparenyldiol
Cat.No: T82956
Synonym: Asparenydiol
Target:
Hemocyanin
Cat.No: T76129
Synonym:
Target: Others
Sophoraisoflavone A
Cat.No: TN2219
Synonym: 鲁冰花,砂生槐异黄酮 A
Target: MRP, Antifection
Shishijimicin C
Cat.No: T81168
Synonym:
Target:
Shishijimicin A
Cat.No: T81170
Synonym:
Target:
Shishijimicin B
Cat.No: T81169
Synonym:
Target:
Lacto-N-neodifucohexaose II
Cat.No: T81958
Synonym: LNnDFH II
Target:
Cat. No. Product Name Species Expression System
TMPY-02209 CUTC Protein, Human, Recombinant (His)

CGI-32,cutC copper transporter

Human E. coli
Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply o...
TMPH-01468 SLC31A1 Protein, Human, Recombinant (His & SUMO)

Copper transporter 1,SLC31A1,High affinity copp...

Human E. coli
SLC31A1 Protein, Human, Recombinant (His & SUMO) is expressed in in vitro E. coli expression system.
TMPY-04122 ATOX1 Protein, Human, Recombinant (His)

HAH1,ATX1,antioxidant 1 copper chaperone

Human E. coli
ATOX1 is a cytoplasmic copper chaperone that interacts with the copper-binding domain of the membrane copper transporters ATP7A and ATP7B. ATOX1 has also been suggested to have a potential anti-oxidant activity. As the trace element copper is essential, but extremely toxic in high concentrations, intracellular copper concentrations are tightly controlled. Once in the cell, copper is distributed by metallochaperones, including the small cytoplasmic protein ATOX1. ATOX1 plays an important role in ...
TMPH-03408 NirK Protein, Rhizobium sullae, Recombinant (His)

nirK,Cu-NIR,Copper-containing nitrite reductase

Rhizobium sullae E. coli
NirK Protein, Rhizobium sullae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.8 kDa and the accession number is Q60214.
TMPY-00140 ABP1/AOC1 Protein, Human, Recombinant (His)

amine oxidase, copper containing 1,DAO,ABP1,ABP,KAO...

Human HEK293 Cells
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co...
TMPJ-00380 AOC3 Protein, Human, Recombinant (His)

Membrane primary amine oxidase,HPAO,VAP-1,Semicarbazide-sens...

Human HEK293 Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf...
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc)

SSAO,AOC3,Membrane primary amine oxidase,Copper ami...

Human HEK293 Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam...
TMPH-01670 Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)

MT4,Metallothionein-4,Metallothionein-IV

Human E. coli
Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
TMPH-01669 Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)

Metallothionein-III,Metallothionein-3,GIFB,MT3,Growth inhibi...

Human E. coli
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
TMPH-02269 Tyrosinase/TYR Protein, Human, Recombinant (His)

Tyrosinase,SK29-AB,Monophenol monooxygenase,Tumor rejection ...

Human P. pastoris (Yeast)
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
TMPJ-00704 SCO1 Protein, Human, Recombinant (GST)

Protein SCO1 Homolog Mitochondrial,SCOD1,SCO1

Human E. coli
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4...
TMPJ-00695 CuTA Protein, Human, Recombinant (His)

C6orf82,Brain Acetylcholinesterase Putative Membrane Anchor,...

Human E. coli
Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a broad range of divalent cations other than copper. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found.
TMPH-00035 Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)

Tyrosinase 2,Cresolase 2,PPO2,Polyphenol oxidase 2

Agaricus bisporus Baculovirus Insect Cells
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell...
TMPH-02270 Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)

SK29-AB,LB24-AB,TYR,Monophenol monooxygenase,Tyrosinase,Tumo...

Human E. coli
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
TMPH-02617 COX5A Protein, Mouse, Recombinant (His & SUMO)

Cytochrome c oxidase subunit 5A, mitochondrial,COX5A,Cytochr...

Mouse E. coli
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over t...
TMPH-01080 Ceruloplasmin Protein, Human, Recombinant (His & Myc)

CP,Ceruloplasmin,Ferroxidase ceruloplasmin,Cuproxidase cerul...

Human E. coli
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. Ceruloplasmin Protein, Human, Recombinant (His & Myc) is expressed in E. co...
TMPY-03852 Dopamine beta-Hydroxylase Protein, Human, Recombinant (His)

dopamine β-hydroxylase (dopamine β-monooxygenase),Dopamine β...

Human HEK293 Cells
DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH contains our identical subunits, and its activity requires ascorbate as a cofactor. It functions in in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine the only transmitter synthesized inside vesicles. DBH has been shown to be associated ...
TMPY-03613 COMMD8 Protein, Human, Recombinant (His)

COMM domain containing 8

Human E. coli
COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis a...
TMPY-01880 PDZD11 Protein, Human, Recombinant (His)

AIPP1,PISP,PDZ domain containing 11,PDZK11

Human E. coli
PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein that contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms t...
TMPJ-01089 TFF1 Protein, Mouse, Recombinant (His)

Bcei,Protein pS2,Ps2,Trefoil factor 1,Tff1

Mouse HEK293 Cells
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and fo...
TMPY-01585 SOD1 Protein, Human, Recombinant (His)

SOD,homodimer,ALS,hSod1,IPOA,superoxide dismutase 1, soluble...

Human E. coli
SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis....
TMPJ-00758 AFP Protein, Mouse, Recombinant (His)

Alpha-fetoprotein,α-fetoglobulin,Alpha-1-fetoprotein,Afp,α-1...

Mouse HEK293 Cells
Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitaminD (Gc) protein, and alpha-albumin. AFP is a major plasma protein produced by the yolk sac and the liver during fetal development. It is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. AFP is one of the several embryo-specific proteins and is adominant serum protein as ea...

重组蛋白

CUTC Protein, Human, Recombinant (His)
Cat.No: TMPY-02209
Species: Human
Expression System: E. coli
SLC31A1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01468
Species: Human
Expression System: E. coli
ATOX1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04122
Species: Human
Expression System: E. coli
NirK Protein, Rhizobium sullae, Recombinant (His)
Cat.No: TMPH-03408
Species: Rhizobium sullae
Expression System: E. coli
ABP1/AOC1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00140
Species: Human
Expression System: HEK293 Cells
AOC3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00380
Species: Human
Expression System: HEK293 Cells
AOC3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00379
Species: Human
Expression System: HEK293 Cells
Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01670
Species: Human
Expression System: E. coli
Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01669
Species: Human
Expression System: E. coli
Tyrosinase/TYR Protein, Human, Recombinant (His)
Cat.No: TMPH-02269
Species: Human
Expression System: P. pastoris (Yeast)
SCO1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-00704
Species: Human
Expression System: E. coli
CuTA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00695
Species: Human
Expression System: E. coli
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)
Cat.No: TMPH-00035
Species: Agaricus bisporus
Expression System: Baculovirus Insect Cells
Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02270
Species: Human
Expression System: E. coli
COX5A Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02617
Species: Mouse
Expression System: E. coli
Ceruloplasmin Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01080
Species: Human
Expression System: E. coli
Dopamine beta-Hydroxylase Protein, Human, Recombinant (His)
Cat.No: TMPY-03852
Species: Human
Expression System: HEK293 Cells
COMMD8 Protein, Human, Recombinant (His)
Cat.No: TMPY-03613
Species: Human
Expression System: E. coli
PDZD11 Protein, Human, Recombinant (His)
Cat.No: TMPY-01880
Species: Human
Expression System: E. coli
TFF1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01089
Species: Mouse
Expression System: HEK293 Cells
SOD1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01585
Species: Human
Expression System: E. coli
AFP Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00758
Species: Mouse
Expression System: HEK293 Cells
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