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Search Results for " aging "

Targets Recommended: NAMPT

76

抑制剂 & 化合物

27

天然产物

10

化合物库

15

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L8200	抗衰老化合物库		3279 compounds
	3279 个抗衰老化合物的独特集合，可用于高通量筛选和高内涵筛选；
L3510	甲基化化合物库		128 compounds
	128 种甲基化相关的化合物，可以用于高通量和高内涵筛选；
L5300	线粒体靶向库		812 compounds
	812 种具有潜在或确定线粒体靶向活性的化合物，以促进针对线粒体的药物研究；
L1200	表观遗传库		953 compounds
	953 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；
L6600	胃肠炎天然产物库		219 compounds
	219 种胃肠炎相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2600	神经信号分子库		2540 compounds
	2540 种CNS 相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L6810	中药单体化合物库		2755 compounds
	2755 种中药来源的单体化合物，是药物开发、药理研究等领域的有力工具；
L2194	抗结直肠癌化合物库		1545 compounds
	1545 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；

化合物库

抗衰老化合物库

Cat.No: L8200

Compounds: 3279

甲基化化合物库

Cat.No: L3510

Compounds: 128

线粒体靶向库

Cat.No: L5300

Compounds: 812

表观遗传库

Cat.No: L1200

Compounds: 953

胃肠炎天然产物库

Cat.No: L6600

Compounds: 219

神经信号分子库

Cat.No: L2600

Compounds: 2540

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

脂代谢化合物库

Cat.No: L2510

Compounds: 492

中药单体化合物库

Cat.No: L6810

Compounds: 2755

抗结直肠癌化合物库

Cat.No: L2194

Compounds: 1545

Cat. No.	Product Name	Target	Signaling Pathways
T12854	SBI-797812	NAMPT	Metabolism
	SBI-797812 是在结构上类似于活性位点定向的 NAMPT 抑制剂的化合物，能够阻断这些抑制剂与 NAMPT 的结合。它将 NAMPT 反应平衡转向 NMN 形成，提高 NAMPT 对 ATP 的亲和力，稳定 His247 处的磷酸化 NAMPT，增加焦磷酸盐副产物的消耗，并通过 NAD+钝化反馈抑制。
TP1253	Argireline 六胜肽,Acetyl hexapeptide-3,阿基瑞林	Others	Others
	Argireline (Acetyl hexapeptide-3) 是可渗透皮肤的、无毒的抗皱肽。它对神经肌肉接头处依赖 Ca2+的神经递质释放具有显著的抑制作用。它具有抗皱和抗衰老的活性。
T2004	Ciproxifan maleate FUB 359 maleate,FUB 359	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Ciproxifan maleate (FUB 359) 是一种选择性的，可口服和竞争性的组胺H3受体拮抗剂，IC50值为 9.2 nM。它对其他受体亚型的表观亲和力低，可用于研究衰老性疾病和阿尔兹海默症。
T7823	IDRA-21 7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪 1,1-二氧化物	GluR	Neuroscience
	IDRA-21 是一种阳性 AMPA 受体调节剂。
T6164	Ciproxifan FUB-359,环丙基[4-[3-(1H-咪唑-4-基)丙氧基]苯基]甲酮马来酸盐	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Ciproxifan (FUB-359) 是一种高效且特异性的组胺 H3 受体拮抗剂，IC50值为 9.2 nM，可用于研究衰老性疾病和阿尔兹海默症。
T9036	N-Isopropyl-N-Phenyl-1,4-Phenylenediamin	Others	Others
	N-Isopropyl-N-Phenyl-1,4-Phenylenediamin 是橡胶防老剂
T60503	MFI8	Mitochondrial Metabolism	Metabolism
	MFI8 是一种调控线粒体裂变的化合物，可用于研究衰老。
T23667	AGN-201904 AGN201904,AGN 201904	ATPase	Membrane transporter/Ion channel
	AGN-201904 是质子泵抑制剂，是一种奥美拉唑前药，可延缓衰老，可用于预防和治疗消化性溃疡。
TP2491	Palmitoyl Dipeptide-5 Acetate Palmitoyl Dipeptide-5 Acetate(794590-34-4 Free base)	Others	Others
	Palmitoyl Dipeptide-5 Acetate 是一种多肽，是一种化妆品原料，可改善皮肤质量，防止皮肤衰老。
TP1291	Epithalon TFA (307297-39-8 free base) Epithalon TFA	Others	Others
	Epithalon TFA (307297-39-8 free base) (Epithalon TFA) 是一种抗衰老剂和端粒酶激活剂。
T23286	S 24795 Catestatin acetate(142211-96-9 free base),LNAChR	AChR	Neuroscience
	S 24795 (Catestatin acetate(142211-96-9 free base)) 是一种 α7 nAChR 部分激动剂。 S 24795 改善了老年小鼠的记忆功能，可用于与衰老相关的记忆障碍的研究。
T1993	J-147 J147	Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase	Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
	J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂，可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体，EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
TP2373L	Biotinoyl tripeptide-1 Acetate Biotinoyl tripeptide-1 Acetate(299157-54-3 Free base)	Others	Others
	Biotinoyl tripeptide-1 Acetate 可通过促进头皮微循环产生毛囊，减少毛囊萎缩和衰老。
TP2489	Tetrapeptide-21 Acetate Tetrapeptide-21 Acetate(960608-17-7 Free base)	Others	Others
	Tetrapeptide-21 Acetate 是一种新型生物活性纯四肽，具有基于皮肤自身结构的抗衰老特性，可用于护肤配方。
T77613	SNX7 WAY-323879	CDK	Cell Cycle/Checkpoint
	SNX7 (WAY-323879) 是细胞周期蛋白依赖性激酶抑制剂 (CDKI) 途径的抑制剂。 SNX7 可用作研究衰老过程和与 CDKI 相关的其他疾病的工具。
T8532	IM156	OXPHOS	Apoptosis
	IM156 (HL156A; HL271 acetate) 是衍生自二甲双胍的化合物，是一种强效的，具有口服活性的AMPK 激活剂。IM156 在动物模型中可缓解与年龄相关的认知下降。IM156 是一种有效的氧化磷酸化 (OXPHOS) 抑制剂，可用于实体肿瘤的研究。
T23046	N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮	ROS; COX	Immunology/Inflammation; Neuroscience
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) 是基于硝酮的自由基清除剂，可形成一氧化氮自旋加合物。它可以穿透血脑屏障，抑制 COX2的催化活性，有 ROS 清除、抗炎、神经保护、抗衰老和抗糖尿病的作用。
T26684	Auten-99 HBr Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99	Phosphatase	Metabolism
	Auten-99 HBr (Auten-99) 是新型肌管蛋白磷酸酶 Jumpy( MTMR14) 的抑制剂，可通过血脑屏障，具有强大的神经保护作用。
T77577	SLU-PP-332	Estrogen/progestogen Receptor	Endocrinology/Hormones
	SLU-PP-332 是一种泛雌激素受体相关受体 (ERR) 激动剂，其对 ERRα, ERRβ 以及 ERRγ 具有很高的亲和力，EC50 值分别为 98、230 以及 430 nM。SLUPP-332 可增强骨骼肌细胞系的线粒体功能和细胞呼吸，增加 IIa 型氧化骨骼肌纤维并增强了运动耐力。SLU-PP-332 具有研究代谢性疾病以及肌肉功能改善的潜力，可能用于改善代谢紊乱和衰老。
T6045	Torin 1	DNA-PK; PI3K; mTOR; Autophagy	Autophagy; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Torin 1 是一种 mTOR 抑制剂，可以抑制 mTORC1 和 mTORC2 (IC50=2/10 nM)，具有选择性和 ATP 竞争性。Torin 1 可以诱导细胞自噬，具有抗肿瘤、抗炎、抗衰老活性。
T11570	HL271	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.
TP2373	Biotinoyl tripeptide-1 Biotin GHK,BiotinGHK,Biotin-GHK
	Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.
T24094	Glycerophosphoinositol lysine Distinctive gpi lysine,Gpi lysine	Others	Others
	Glycerophosphoinositol lysine has an anti-dandruff, anti-inflammatory, anti-aging activity. It significantly suppresses UVB - induced PGE secretion in NHEK keratinocytes.
T81978	KLKKTETQ
	KLKKTETQ 是一种生物活性肽，具有抗衰老(anti-aging)功效，已报导应用于化妆品成分。
T80201	Tripeptide-32	Caspase	Apoptosis; Proteases/Proteasome
	Tripeptide-32，一种生物活性肽，具备抗衰老(anti-aging)功能，已报告作为化妆品成分使用。
T81006	Tetrapeptide-26
	Tetrapeptide-26，一种生物活性肽，具抗衰老(anti-aging)功能，常用作化妆品成分。
T80948	Trifluoroacetyl tripeptide-2
	Trifluoroacetyl tripeptide-2，一种生物活性肽，具抗衰老（anti-aging）功能，被报道为化妆品配料。
T81562	Palmitoyl tripeptide-5
	Palmitoyl tripeptide-5，一种生物活性肽，具备抗衰老(anti-aging)效果，常用作化妆品成分。
T80944	Tripeptide-10 citrulline T10-C
	Tripeptide-10 citrulline(T10-C)，一种生物活性肽，具备抗衰老(anti-aging)功能，广泛应用于化妆品成分。
T83199	Acetyl hexapeptide-37
	Acetyl hexapeptide-37是一种生物活性肽，具抗衰老(anti-aging)功能，常作为化妆品成分使用。
T81612	Oligopeptide-68
	Oligopeptide-68，生物活性肽，具备抗衰老（anti-aging）特性，报道常用作化妆品成分。
T83194	Acetylarginyltryptophyl diphenylglycine
	Acetylarginyltryptophyl diphenylglycine 是抗衰老(anti-aging)生物活性肽，已报道作为化妆品成分使用。
T81518	Pentapeptide-31
	Pentapeptide-31，一种生物活性肽，具抗衰老(anti-aging)功能，已报道应用于化妆品成分。
T83190	Acetyltetrapeptide 11
	Acetyltetrapeptide-11，生物活性肽，具抗衰老（anti-aging）功效，报道用于化妆品成分。
T81566	Palmitoyl hexapeptide-12
	Palmitoyl hexapeptide-12，一种生物活性肽，具抗衰老(anti-aging)功能，常作为化妆品原料。
T83203	Acetyl dipeptide-1 cetyl ester Calmosensine
	Acetyl dipeptide-1 cetyl ester(Calmosensine)为一种具抗衰老(anti-aging)功能的生物活性肽，常作为化妆品成分。
T83198	Acetyl sh-heptapeptide-1
	Acetyl sh-heptapeptide-1，一种多肽，有效对抗面部老化。
T83202	Acetyl dipeptide-3 aminohexanoate
	Acetyl dipeptide-3 aminohexanoate为生物活性肽，具抗衰老(anti-aging)功能，广泛应用于化妆品成分。
T81230	SA1-III KP1
	SA1-III(KP1)为具抗衰老(anti-aging)功能的生物活性肽，已报道作为化妆品成分使用。
T81567	Palmitoyl dipeptide-5 diaminohydroxybutyrate
	Palmitoyl dipeptide-5 diaminohydroxybutyrate，一种生物活性肽，具有抗衰老 (anti-aging) 功能，常作为化妆品成分使用。
T21035	Rufloxacin MF 934	Others	Others
	Rufloxacin is a drug that belongs to the class of fluoroquinolones, which act mainly as specific inhibitors of bacterial Topoisomerase II. These drugs involve in various diseases including cutaneous reactions, aging, etc.
T80027	Palmitoyl tripeptide-38	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Palmitoyl tripeptide-38是生物活性肽，具有抗老化效果。
TP2354	Tetrapeptide-11 Pro-pro-tyr-leu
	Tetrapeptide-11 is the reaction product of Acetic Acid and tetrapeptide-11, containing leucine, proline, and tyrosine residues. It boosts cell growth, Syndecan-1, and Collagen XVII synthesis. Tetrapeptide-11 has a face and body anti-wrinkle and anti-aging
T61684	S 17092	Others	Others
	S 17092 (S 17092-1) is a highly effective inhibitor of cerebral prolyl-endopeptidase (PEP), displaying an IC50 value of 1.2 nM. It is utilized in research focused on understanding memory impairment and cognitive disorders associated with cerebral aging [1].
T81564	Palmitoyl tetrapeptide-10
	Palmitoyl tetrapeptide-10，一种生物活性肽，具有抗衰老功能，已报道用于化妆品成分。
T81568	Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
	Palmitoyl dipeptide-7, 一种化妆品成分，以其生物活性肽特性作用于抗衰老。
T82206	Hexapeptide-12
	Hexapeptide-12为一生物活性肽，具抗衰老功能，现报道应用于化妆品成分中。
T10029	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine	Endogenous Metabolite	Metabolism
	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine 是内源性代谢产物的一种。
T35892	Q134R Q134R	Others	Others
	Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer’s disease (AD) and aging-related disorders research[1]. Q134R (1-10 μM) suppresses NFAT signaling, without inhibiting calcineurin activity. Q134R partially inhibits NFAT activity in primary rat astrocytes, but does not prevent calcineurin-mediated dephosphorylation of a non-NFAT target, either in vivo...
T82200	H-Gly-Pro-Hyp-OH Tripeptide 29
	Tripeptide-29 (H-Gly-Pro-Hyp-OH) 是作为化妆品成分被报道的一种具有口服抗UVB诱导皮肤衰老效果的生物活性肽。

化合物

Cat.No: T12854

Target: NAMPT

Cat.No: TP1253

Synonym: 六胜肽,Acetyl hexapeptide-3,阿基瑞林

Target: Others

Ciproxifan maleate

Cat.No: T2004

Synonym: FUB 359 maleate,FUB 359

Target: Histamine Receptor

Cat.No: T7823

Synonym: 7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪 1,1-二氧化物

Target: GluR

Cat.No: T6164

Synonym: FUB-359,环丙基[4-[3-(1H-咪唑-4-基)丙氧基]苯基]甲酮马来酸盐

Target: Histamine Receptor

N-Isopropyl-N-Phenyl-1,4-Phenylenediamin

Cat.No: T9036

Target: Others

Cat.No: T60503

Target: Mitochondrial Metabolism

Cat.No: T23667

Synonym: AGN201904,AGN 201904

Target: ATPase

Palmitoyl Dipeptide-5 Acetate

Cat.No: TP2491

Synonym: Palmitoyl Dipeptide-5 Acetate(794590-34-4 Free base)

Target: Others

Epithalon TFA (307297-39-8 free base)

Cat.No: TP1291

Synonym: Epithalon TFA

Target: Others

Cat.No: T23286

Synonym: Catestatin acetate(142211-96-9 free base),LNAChR

Target: AChR

Cat.No: T1993

Synonym: J147

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

Biotinoyl tripeptide-1 Acetate

Cat.No: TP2373L

Synonym: Biotinoyl tripeptide-1 Acetate(299157-54-3 Free base)

Target: Others

Tetrapeptide-21 Acetate

Cat.No: TP2489

Synonym: Tetrapeptide-21 Acetate(960608-17-7 Free base)

Target: Others

Cat.No: T77613

Synonym: WAY-323879

Target: CDK

Cat.No: T8532

Target: OXPHOS

N-tert-butyl-α-Phenylnitrone

Cat.No: T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮

Target: ROS, COX

Cat.No: T26684

Synonym: Auten-99,Auten-99 hydrochloride. Auten-99 HBr,Auten99,Auten 99

Target: Phosphatase

Cat.No: T77577

Target: Estrogen/progestogen Receptor

Cat.No: T6045

Target: DNA-PK, PI3K, mTOR, Autophagy

Cat.No: T11570

Target: AMPK

Biotinoyl tripeptide-1

Cat.No: TP2373

Synonym: Biotin GHK,BiotinGHK,Biotin-GHK

Glycerophosphoinositol lysine

Cat.No: T24094

Synonym: Distinctive gpi lysine,Gpi lysine

Target: Others

Cat.No: T81978

Cat.No: T80201

Target: Caspase

Tetrapeptide-26

Cat.No: T81006

Trifluoroacetyl tripeptide-2

Cat.No: T80948

Palmitoyl tripeptide-5

Cat.No: T81562

Tripeptide-10 citrulline

Cat.No: T80944

Synonym: T10-C

Acetyl hexapeptide-37

Cat.No: T83199

Oligopeptide-68

Cat.No: T81612

Acetylarginyltryptophyl diphenylglycine

Cat.No: T83194

Pentapeptide-31

Cat.No: T81518

Acetyltetrapeptide 11

Cat.No: T83190

Palmitoyl hexapeptide-12

Cat.No: T81566

Acetyl dipeptide-1 cetyl ester

Cat.No: T83203

Synonym: Calmosensine

Acetyl sh-heptapeptide-1

Cat.No: T83198

Acetyl dipeptide-3 aminohexanoate

Cat.No: T83202

Cat.No: T81230

Synonym: KP1

Palmitoyl dipeptide-5 diaminohydroxybutyrate

Cat.No: T81567

Cat.No: T21035

Synonym: MF 934

Target: Others

Palmitoyl tripeptide-38

Cat.No: T80027

Target: Reactive Oxygen Species

Tetrapeptide-11

Cat.No: TP2354

Synonym: Pro-pro-tyr-leu

Cat.No: T61684

Target: Others

Palmitoyl tetrapeptide-10

Cat.No: T81564

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine

Cat.No: T81568

Cat.No: T82206

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

Cat.No: T10029

Target: Endogenous Metabolite

Cat.No: T35892

Synonym: Q134R

Target: Others

H-Gly-Pro-Hyp-OH

Cat.No: T82200

Synonym: Tripeptide 29

Cat. No.	Product Name	Target	Signaling Pathways
T3S1265	Liriopesides B 山麦冬皂苷B,Nolinospiroside F	Others	Others
	Liriopesides B (Nolinospiroside F) 是一种甾体皂苷，分离自 Ophiopogon japonicas 中，具有抗氧化和抗衰老活性。
T3416	Aucubin Aucuboside,桃叶珊瑚苷,Rhinanthin	IL Receptor; NF-κB; Antibacterial	Immunology/Inflammation; Microbiology/Virology; NF-κB
	Aucubin (Rhinanthin) 是一种可从许多传统的草药中提取的环烯醚萜苷，有许多生物学活性。
TN2019	Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮	BCL; Caspase; PI3K	Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K，对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
T3768	Epifriedelanol 表木栓醇,Epifriedelinol	Others	Others
	Epifriedelanol (Epifriedelinol) 是一种分离自 Ulmus davidiana 根皮中的三萜类化合物，具有抗肿瘤作用，可以减缓人原始细胞的衰老。
T78498	Oxyphyllacinol	Antioxidant	oxidation-reduction
	Oxyphyllacinol 是从 Alpinia oxyphylla果实中分离得到的化合物，具有潜在的抗氧化和抗衰老活性，可用于研究痴呆。
T4732	L-Carnosine Karnozin,L-肌肽,beta-Alanyl-L-histidine	Antioxidant; Endogenous Metabolite	Metabolism; oxidation-reduction
	L-Carnosine (Karnozin) 是由beta-丙氨酸和组氨酸组成的二肽，具有抑制衰老的作用。
TN1296	5-Feruloylquinic acid 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸	Tyrosinase; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	5-Feruloylquinic acid (5-FQA) 表现出抗氧化作用和酪氨酸酶抑制作用。
TJO2691	(-)-Fucose L-岩藻糖,Madecassic acid,L-(-)-Fucose,L-Galactomethylose,Brahmic acid,6-Desoxygalactose	Endogenous Metabolite; Parasite	Metabolism; Microbiology/Virology
	(-)-Fucose (6-Desoxygalactose) 是己糖中的一种，有抗感染、抗癌、增强免疫力、皮肤保湿和延缓皮肤衰老作用。
T22218	2'-Deoxyguanosine Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine (Guanine deoxyriboside) 是一种嘌呤核苷，可被2'-dG-II家族的成员识别。2'-Deoxyguanosine 与衰老、突变和致癌有关，可被分子氧氧化。
T3812	(20R)-Ginsenoside Rg3 人参皂甙 RG3,(20R)-人参皂苷Rg3,20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol	Others	Others
	(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) 是一种人参根中的化合物，具有抑制血管内皮细胞增生（IC50= 10 nM）和抗肿瘤作用。
T2813	Madecassoside Asiaticoside A,羟基积雪草苷	Apoptosis; Antioxidant; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	Madecassoside (Asiaticoside A) 是从崩大碗中分离出来的一种五环三萜，有抗炎症，抗氧化和抗衰老的作用。
TMS0418	Dihydroergotoxine mesylate 甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Dihydroergotoxine mesylate (Ergoloid mesylates) 是系列生物碱盐混合物，对GABAA 受体高结合活性。它主要用于改善与衰老相关的精神退化的症状和身体症状。
T2S0842	Scutellarin methyl ester Scutellarin methylester,野黄芩苷甲酯	Others	Others
	Scutellarin methyl ester (3-Oxotirucallenoic Acid) 是一种灯盏花素的成分, 其中灯盏花素是灯盏花中几种黄酮类化合物的粗提物。
T3018	Protocatechualdehyde Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde,原儿茶醛	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Protocatechualdehyde (3,4-Dihydroxybenzaldehyde)，源自丹参根的天然多酚化合物，展现多样生物活性，并作为抗氧化剂、抗衰老剂、抗菌剂和抗炎剂在医药领域广泛应用。
T3911	Pulchinenoside A 白头翁皂苷A,Anemoside A3	Others	Others
	Pulchinenoside A (Anemoside A3) 是一种天然的白头翁皂苷 A，也是 NMDA 受体的非竞争性的调节器，能够提高成年老鼠的海马体突触可塑性和醋精成年老鼠的空间记忆。
TMS2182	trans-Zeatinriboside Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷	Others	Others
	trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体，是木质素导管中主要的长距离信号形式，能够调节叶片大小和分生组织活性相关形状。
T0591	D-Galactose D-(+)-Galactose,alpha-D-半乳糖,D-半乳糖,D-Galactopyranose,Alpha-D-galactose	Endogenous Metabolite	Metabolism
	D-Galactose (Alpha-D-galactose) 属于天然己糖，与葡萄糖结合构成乳糖。D-Galactose 常被用于构建动物衰老模型。
TN1088	3,5,6,7,8,3',4'-Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮	Others	Others
	3,5,6,7,8,3',4'-Heptemthoxyflavone 是来自蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症作用。它能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子表达，降低 C6 细胞磷酸二酯酶活性。它能抑制胶原酶的活性，增加人真皮成纤维细胞新生细胞中 I 型前胶原含量。
TN1594	DL-Syringaresinol (±)-Syringaresinol	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	DL-Syringaresinol ( (±)-Syringaresinol) 是一种来自与人参浆果的木质素，具有抗炎、抗氧化、镇痛活性和较弱的抗分枝杆菌活性。DL-Syringaresinol 可通过自噬延缓氧化应激诱导的皮肤老化，通过抑制炎症反应来缓解奥沙利铂诱导的神经性疼痛和脓毒症引起的心功能障碍。
TMS1461	Qingyangshengenin B 青阳参甙元B,青阳参苷元B,Otophylloside B	Beta Amyloid	Neuroscience
	Qingyangshengenin B (Otophylloside B) 是一种分离自 Qingyangshen 的 C-21 甾体苷。它能够在 mRNA 水平上抑制 Aβ 的表达来减少 Aβ 的沉积，对 Aβ 的毒性有保护作用。它具有抗癫痫作用。
T2O2733	L-Cystine Cystine Acid,cystine,胱氨酸,L-胱氨酸	Antioxidant; Ferroptosis; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用，保护组织免受辐射和污染，减缓衰老过程。它还有助于蛋白质合成。
T4971	5'-DEOXYADENOSINE 5′-dAdo,5-脱氧腺嘌呤核苷	Endogenous Metabolite	Metabolism
	5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷，氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。
T2864	Lycopene 番茄红素,ψ,ψ-Carotene	Reactive Oxygen Species; ROS	Immunology/Inflammation; Metabolism; NF-κB
	Lycopene (ψ,ψ-Carotene) 是一种番茄及其产品和其他红色水果和蔬菜中天然存在的类胡萝卜素，具有抗氧化活性。
T4725	N-Acetyl-D-mannosamine N-乙酰-D-甘露糖胺,2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-D-mannosamine 是一种单糖，在糖脂和糖蛋白中发现的神经氨酸的化学或酶合成中用作前体。N-Acetyl-D-mannosamine 是合成细菌荚膜聚唾液酸(PA)必需前体n -乙酰神经氨酸的特异性底物。N-Acetyl-D-mannosamine 用于合成唾液酸。它也是许多碳水化合物衍生的生物活性化合物家族和候选药物的合成中间体。N-Acetyl-D-mannosamine 可用于研究认知障碍和衰老。
T0795	Rutin Quercetin 3-O-rutinoside,芦丁,Rutoside	Beta Amyloid; Prostaglandin Receptor; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Rutin (Quercetin 3-O-rutinoside) 属于黄酮类天然产物，具有血脑屏障渗透性。Rutin 具有广泛的生物活性，包括抗氧化、抗炎、抗肿瘤、降血糖、神经保护、抗菌、抗衰老等等。
TN3968	Epifriedelanol acetate	Others	Others
	Epifriedelanol exhibits antibacterial activities. It also can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol and friedel
T78539	(+)-Coclaurine hydrochloride d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride	Others	Others
	(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride 是从多种植物中分离得到的四氢异喹啉类生物碱，具有抗衰老活性。

天然产物

Cat.No: T3S1265

Synonym: 山麦冬皂苷B,Nolinospiroside F

Target: Others

Cat.No: T3416

Synonym: Aucuboside,桃叶珊瑚苷,Rhinanthin

Target: IL Receptor, NF-κB, Antibacterial

Cat.No: TN2019

Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

Target: BCL, Caspase, PI3K

Cat.No: T3768

Synonym: 表木栓醇,Epifriedelinol

Target: Others

Cat.No: T78498

Target: Antioxidant

Cat.No: T4732

Synonym: Karnozin,L-肌肽,beta-Alanyl-L-histidine

Target: Antioxidant, Endogenous Metabolite

5-Feruloylquinic acid

Cat.No: TN1296

Synonym: 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸

Target: Tyrosinase, Sirtuin

Cat.No: TJO2691

Synonym: L-岩藻糖,Madecassic acid,L-(-)-Fucose,L-Galactomethylose,Brahmic acid,6-Desoxygalactose

Target: Endogenous Metabolite, Parasite

2'-Deoxyguanosine

Cat.No: T22218

Synonym: Deoxyguanosine,Guanine deoxyriboside

Target: Endogenous Metabolite

(20R)-Ginsenoside Rg3

Cat.No: T3812

Synonym: 人参皂甙 RG3,(20R)-人参皂苷Rg3,20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol

Target: Others

Cat.No: T2813

Synonym: Asiaticoside A,羟基积雪草苷

Target: Apoptosis, Antioxidant, Endogenous Metabolite

Dihydroergotoxine mesylate

Cat.No: TMS0418

Synonym: 甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱

Target: GABA Receptor

Scutellarin methyl ester

Cat.No: T2S0842

Synonym: Scutellarin methylester,野黄芩苷甲酯

Target: Others

Protocatechualdehyde

Cat.No: T3018

Synonym: Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde,原儿茶醛

Target: Reactive Oxygen Species, Antibacterial

Pulchinenoside A

Cat.No: T3911

Synonym: 白头翁皂苷A,Anemoside A3

Target: Others

trans-Zeatinriboside

Cat.No: TMS2182

Synonym: Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷

Target: Others

Cat.No: T0591

Synonym: D-(+)-Galactose,alpha-D-半乳糖,D-半乳糖,D-Galactopyranose,Alpha-D-galactose

Target: Endogenous Metabolite

3,5,6,7,8,3',4'-Heptemthoxyflavone

Cat.No: TN1088

Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone,3,5,6,7,8,3',4'-七甲氧基黄酮

Target: Others

DL-Syringaresinol

Cat.No: TN1594

Synonym: (±)-Syringaresinol

Target: Antioxidant, Antifungal

Qingyangshengenin B

Cat.No: TMS1461

Synonym: 青阳参甙元B,青阳参苷元B,Otophylloside B

Target: Beta Amyloid

Cat.No: T2O2733

Synonym: Cystine Acid,cystine,胱氨酸,L-胱氨酸

Target: Antioxidant, Ferroptosis, Endogenous Metabolite

5'-DEOXYADENOSINE

Cat.No: T4971

Synonym: 5′-dAdo,5-脱氧腺嘌呤核苷

Target: Endogenous Metabolite

Cat.No: T2864

Synonym: 番茄红素,ψ,ψ-Carotene

Target: Reactive Oxygen Species, ROS

N-Acetyl-D-mannosamine

Cat.No: T4725

Synonym: N-乙酰-D-甘露糖胺,2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE

Target: Others, Endogenous Metabolite

Cat.No: T0795

Synonym: Quercetin 3-O-rutinoside,芦丁,Rutoside

Target: Beta Amyloid, Prostaglandin Receptor, Autophagy

Epifriedelanol acetate

Cat.No: TN3968

Target: Others

(+)-Coclaurine hydrochloride

Cat.No: T78539

Synonym: d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00278	Clusterin Protein, Human, Recombinant (hFc & His) CLU,NA1/NA2,TRPM-2,40,Apo-J,Clusterin,Complement Cytolysis I...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.
TMPJ-00279	Clusterin Protein, Human, Recombinant (His) Clusterin,Ku70-Binding Protein 1,Apo-J,Testosterone-Represse...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909.
TMPY-02550	Eotaxin/CCL11 Protein, Human, Recombinant (His) SCYA11,chemokine (C-C motif) ligand 11	Human	E. coli
	CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small ...
TMPH-00509	Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc) Protein-L-isoaspartate(D-aspartate) O-methyltransferase,Prot...	Fruit fly	E. coli
	Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins. Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession number is Q27869.
TMPJ-01053	UBE2I Protein, Human, Recombinant (GST) SUMO-Protein Ligase,Ubiquitin-Conjugating Enzyme E2 I,p18,UB...	Human	E. coli
	SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, UBC9 conjugates a ubiquitin homologue, Small Ubiquitin-Like Modifier 1 (SUMO-1). The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging.
TMPH-02621	DAO Protein, Mouse, Recombinant (His) DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase	Mouse	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system...
TMPH-03276	DAO Protein, Rat, Recombinant (His & Myc) D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO	Rat	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy...
TMPY-00319	GIP Protein, Human, Recombinant (hFc) gastric inhibitory polypeptide,GIP	Human	HEK293 Cells
	Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation. GIP is involved in fat accumulation and insulin resistance with aging. Glucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone with a broad range of physiological actions. Elevated concentrations of the incretin hormone GIP are found in patients with atherosclerotic cardiovascular disease, while GIP treatment attenuates atherosclerotic plaque inflammation in mi...
TMPY-02298	ACYP2 Protein, Human, Recombinant (GST) ACYM,acylphosphatase 2, muscle type,ACYP	Human	E. coli
	Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 a...
TMPY-03456	SRFBP1 Protein, Human, Recombinant (His & GST) STRAP,BUD22,P49,serum response factor binding protein 1,p49/...	Human	Baculovirus Insect Cells
	SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. SRFBP1 negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein. SRF...
TMPJ-00853	DAO Protein, Human, Recombinant (His) D-Amino-Acid Oxidase,DAMOX,DAAO,DAO	Human	E. coli
	D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a...
TMPJ-00923	Calnexin Protein, Human, Recombinant (His) p90,Calnexin,CANX,Major Histocompatibility Complex Class I A...	Human	HEK293 Cells
	Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may ...
TMPY-01618	GLO1 Protein, Mouse, Recombinant (His) glyoxalase I,Glo-1r,GLY1,Glo1-r,2510049H23Rik,Glo1-s,AW55064...	Mouse	E. coli
	Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellul...
TMPH-02186	TERT Protein, Human, Recombinant (His) Telomerase reverse transcriptase,Telomerase catalytic subuni...	Human	E. coli
	Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-de...
TMPH-02841	Prohibitin Protein, Mouse, Recombinant (His) Phb1,B-cell receptor-associated protein 32,Prohibitin 1	Mouse	E. coli
	Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with...

重组蛋白

Clusterin Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00278

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00279

Species: Human

Expression System: HEK293 Cells

Eotaxin/CCL11 Protein, Human, Recombinant (His)

Cat.No: TMPY-02550

Species: Human

Expression System: E. coli

Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc)

Cat.No: TMPH-00509

Species: Fruit fly

Expression System: E. coli

UBE2I Protein, Human, Recombinant (GST)

Cat.No: TMPJ-01053

Species: Human

Expression System: E. coli

DAO Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02621

Species: Mouse

Expression System: E. coli

DAO Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03276

Species: Rat

Expression System: E. coli

GIP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00319

Species: Human

Expression System: HEK293 Cells

ACYP2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02298

Species: Human

Expression System: E. coli

SRFBP1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03456

Species: Human

Expression System: Baculovirus Insect Cells

DAO Protein, Human, Recombinant (His)

Cat.No: TMPJ-00853

Species: Human

Expression System: E. coli

Calnexin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00923

Species: Human

Expression System: HEK293 Cells

GLO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01618

Species: Mouse

Expression System: E. coli

TERT Protein, Human, Recombinant (His)

Cat.No: TMPH-02186

Species: Human

Expression System: E. coli

Prohibitin Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02841

Species: Mouse

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0164	L-Carnosine-d4
	L-Carnosine-d4 是 L-Carnosine 的氘代化合物。L-Carnosine 的 CAS 号为 305-84-0。L-Carnosine 是由beta-丙氨酸和组氨酸组成的二肽，具有抑制衰老的作用。

同位素标记化合物

Cat.No: TMID-0164

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