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重组蛋白 细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体 •   受体酪氨酸激酶 CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白 CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白
信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道
代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
活性化合物库 上市药物库 临床期小分子药物库 已知活性化合物库 FDA上市及药典收录分子库 抗癌药物库 抗病毒库 铁死亡化合物库
天然产物库 高通量筛选天然产物库 Ro5类药天然产物库 中药单体化合物库 糖类及苷类化合物库 稀有天然产物库 天然产物衍生物库 天然产物单体化合物库
Fragment片段库 高溶解性片段库 精选片段库 高溶解性多官能团片段化合物库 高溶解性卤化片段化合物库 药物片段库 Mini片段亲电杂环化合物库 高溶解性微型片段化合物库
类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
苯丙烷 生物碱 酚类 其他
植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
莲叶桐科 胡桃科 石杉科 桔梗科 百合科 忍冬科 漆树科
计算机辅助药物设计 虚拟筛选 分子对接 反向找靶 分子动力学模拟
基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
病毒蛋白 •   冠状病毒蛋白 •   流感病毒蛋白 荧光蛋白 其他蛋白

搜索结果

Search Results for " h2-receptor "
Targets Recommended: P450 Antibacterial Histamine Receptor

71

抑制剂 & 化合物

3

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T0865 Ranitidine Hydrochloride

AH19065,盐酸雷尼替丁

 P450; Antibacterial; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
Ranitidine Hydrochloride (AH19065) 是一种具有口服活性的组胺 H2 受体选择性拮抗剂，IC50为 3.3 μM。它还是一种CYP2C19和CYP2C9的弱抑制剂，可抑制胃液分泌。
T3610 Ranitidine

雷尼替丁,HSDB 3925,Ranitidin

 P450; Antibacterial; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
Ranitidine (HSDB 3925) 是一种选择性的，具有口服活性的组胺 H2 受体拮抗剂，IC50为 3.3 μM。它还一种是CYP2C19和CYP2C9的弱抑制剂，可抑制胃液分泌。
T7524 Metiamide

甲硫米特,SK&F 92058

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Metiamide (SK&F 92058) 是一种组胺H2受体拮抗剂。
T15195 Ebrotidine

FI3542,乙溴替丁

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ebrotidine (FI3542) 是有效的、竞争性的H2受体的拮抗剂，Ki 为127.5nM。Ebrotidine 具有抗分泌活性，可用于胃保护。
T0157 Roxatidine Acetate hydrochloride

HOE 760,盐酸罗沙替丁醋酸酯,Roxatidine Acetate HCl

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Roxatidine Acetate hydrochloride (HOE 760) 是一种特异性和竞争性的组胺 H2 受体拮抗剂，能抑制胃酸分泌，可用于胃溃疡和十二指肠溃疡的研究。
T1575 Nizatidine

Axid,Acinon,尼扎替丁,Zanizal

 AChE; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Nizatidine (Acinon) 是一种竞争性和可逆的组胺 H2 受体拮抗剂，具有抗酸活性，可用于胃溃疡的研究。
T22848 ICI 162,846

Others Others
histamine H2 receptor antagonist
T31195 Dalcotidine

KU 1257,KU-1257

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dalcotidine (KU 1257) 是一种新型组胺H2受体拮抗剂，具有组胺H9受体拮抗活性和抗分泌作用，与豚鼠大脑皮层结合的Ki 值为0.040 对分离性豚鼠右心房组胺诱导的正变时反应的拮抗作用的KB 值为0.041。Dalcotidine 提高了溃疡愈合的质量，可能有助于降低溃疡的复发率和复发率。
T68056 Donetidine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Donetidine 是一种组胺 H2 受体拮抗剂，可用于治疗消化系统疾病。
T68146 Sufotidine

AH 25352X,AH25352X,AH-25352X

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Sufotidine (AH 25352X) 是一种具有高度选择性的竞争性 H2 受体拮抗剂。
T68122L Oxmetidine FA

Oxmetidine FA(72830-39-8 Free base)

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Oxmetidine FA 是一种可口服的特异性组胺 H2 受体拮抗剂，具有抗溃疡作用。
T22842 HTMT dimaleate

HTMT马来酸氢盐,Histamine Trifluoromethyl Toluidide Dimaleate

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
HTMT dimaleate (Histamine Trifluoromethyl Toluidide Dimaleate) 是一种 H1 和 H2 受体激动剂。在自然抑制细胞中，它在 H2 受体介导的效应中的活性是组胺的 4 x 104倍。
T1627 Famotidine

MK-208,法莫替丁

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Famotidine (MK-208) 是一种具有抗酸活性的丙脒和组胺 H2 受体拮抗剂。
T68921 Impromidine hydrochloride

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Impromidine hydrochloride 是一种非常有效和特异性的组胺H2受体激动剂，可用于进行心血管研究。
T68100 Mifentidine

DA 4577

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Mifentidine (DA 4577) 是一种可口服的 H2 受体拮抗剂，可用于研究胃排空和实验性胃和十二指肠溃疡。
T23811L BMY 25368 HCl

BMY 25368 HCl（86134-80-7 Free base)

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
BMY 25368 HCl 是一种竞争性组胺 H2 受体拮抗剂，拮抗由五他胃泌素、乙胆碱和食物刺激的胃分泌。
T22724 Dimaprit dihydrochloride

NOS; NO Synthase; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dimaprit dihydrochloride 是组胺H2受体的一种选择性激动剂，可刺激胃酸的分泌。它还抑制nNOS，IC50值为 49 μM。
T10000 (±)-Tazifylline

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
(±)-Tazifylline 是一种选择性的长效组胺 H1 受体拮抗剂。 Tazifylline 对 H2 受体、α- 和 β-肾上腺素能受体、5-羟色胺和毒蕈碱受体亚型的亲和力要低得多。
T8599 Betazole dihydrochloride

盐酸倍他唑,Betazole hydrochloride

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Betazole dihydrochloride (Betazole hydrochloride) 是吡唑类组胺，是一种口服活性 H2受体激动剂，能诱导胃酸分泌，导致胆总管压力立即显著升高。它作为一种诊断剂，用于研究胃酸分泌能力。
T68122 Oxmetidine

SKF 92994,Oxmetidina,Oxmetidinum

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Oxmetidine (SKF 92994) 是一种新型 H2 受体拮抗剂，具有细胞毒性。 Oxmetidine 抑制心脏和血管组织中跨膜钙通量,可用于治疗活动性十二指肠溃疡。
T6415 Bismuth Subcitrate Potassium

SARS-CoV Microbiology/Virology
Bismuth Subcitrate Potassium 是一种对 12 种幽门螺杆菌有作用的抗生素，抑制组胺H2受体，可用于研究 SARS-CoV-2 感染脆弱患者的腹泻和消化性溃疡病。
T2533 Alcaftadine

R89674,Lastacaft,阿卡他定

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Alcaftadine (Lastacaft) 是一种 H1 组胺受体拮抗剂，用于预防与过敏性结膜炎相关的瘙痒。它是一种广谱抗组胺剂，对组胺H1和H2受体具有高亲和力，对H4受体的亲和力较低，还具有调节免疫细胞募集和肥大细胞稳定的作用。
T11324 FRG8701

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.
T13163 Tiotidine

ICI 125211

 Others Others
Tiotidine is a selective histamine H2-receptor antagonist (pA2=7.3-7.8 for guinea-pig right atrium).
T12228 Niperotidine

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Niperotidine is an antagonist of histamine H2-receptor.
T23565 Zolantidine dimaleate

Others Others
H2 receptor antagonist
T70297 IY-80843

Others Others
IY-80843 is an H2-receptor antagonist.
T13382 Zaltidine

CP-57361

 Others Others
Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.
T71086 IT-066 HCl

Others Others
IT-066 HCl is a histamine H2 receptor antagonist.
T23941 DA 4360

DA4360,DA-4360

 Others Others
DA 4360 is an H2-receptor antagonist. The compounds which were investigated in a wider concentration range, behaved as simple competitive antagonists, yielding apparent KB values comparable with those estimated in conventional H2-receptor assays.
T26039 Ramixotidine

Others Others
Ramixotidine is a competitive antagonist of histamine H2-receptor.
T10575 BMY-25271

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
BMY-25271 is an antagonist of histamine H2 receptor.
T68479 Orf 17910

Others Others
Orf 17910 is a histamine H2-receptor antagonist.
T68704 Orf 17583

Others Others
Orf 17583 is a histamine H2-receptor antagonist.
T23943 DA 4643

DA-4643,DA4643

 Others Others
DA 4643 is one of the histamine H2-receptor antagonists. Both mifentidine and DA 4643 interact with the histamine H2-receptor at the same site, utilizing in the binding process the same, or closely similar, receptor structural features.
T28613 RP73870

RP 73870,RP-73870

 Others Others
RP73870 is a gastrin/cholecystokinin-B receptor antagonist and H2 receptor antagonist with potent anti-ulcer activity.
T15722 Lavoltidine

Loxtidine,AH-234844

 Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lavoltidine is an orally active and irreversible histamine H2-receptor antagonist. Lavoltidine strongly suppresses gastric acid secretion and also induces hypergastrinemia.
T23811 BMY-25368

BMY25368

 Others Others
BMY-25368 is a long-acting antagonist of the H2-receptor.
T71529 NO 794

Others Others
NO 794 is a histamine H2-receptor antagonist.
T23942 DA 4626

DA4626,DA-4626

 Others Others
DA 4626 is H2-receptor antagonism. The compound which was investigated in a wider concentration range, behaved as simple competitive antagonists, yielding apparent KB values comparable with those estimated in conventional H2-receptor assays.
T68747 Orf 17578

Others Others
Orf 17578 is a histamine H2-receptor antagonist.
T24162 Impromidine

Impromidina,Impromidinum

 Others Others
Impromidine is a highly potent and specific agonist of the histamine H2 receptor.
T71390 AY 29315

Others Others
AY 29315 is a histamine H2-receptor antagonist with antisecretory and antiulcer activities.
T70709 FCE-27262

Others Others
FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.
T35288 Z 300

Z-300,Z300

 Others Others
Z 300 是一种组胺 H2 受体拮抗剂。 Z 300 抑制胃酸分泌并促进胃体区域的胃粘液代谢。
T71928 Nordimaprit dihydrochloride

Others Others
Nordimaprit dihydrochloride is a metabolite of Dimaprit -- a histamine analog and selective H2 histamine receptor agonist.
T71470 Famotidine hydrochloride

Others Others
Famotidine hydrochloride is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
T70127 Famotine

Others Others
Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T71049 Famotidine disulfide

Others Others
Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T31743 Famotine hydrochloride

Famotine HCl,UK-2054

 Others Others
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease.

化合物

Ranitidine Hydrochloride
Cat.No: T0865
Synonym: AH19065,盐酸雷尼替丁
Target: P450, Antibacterial, Histamine Receptor
Ranitidine
Cat.No: T3610
Synonym: 雷尼替丁,HSDB 3925,Ranitidin
Target: P450, Antibacterial, Histamine Receptor
Metiamide
Cat.No: T7524
Synonym: 甲硫米特,SK&F 92058
Target: Histamine Receptor
Ebrotidine
Cat.No: T15195
Synonym: FI3542,乙溴替丁
Target: Histamine Receptor
Roxatidine Acetate hydrochloride
Cat.No: T0157
Synonym: HOE 760,盐酸罗沙替丁醋酸酯,Roxatidine Acetate HCl
Target: Histamine Receptor
Nizatidine
Cat.No: T1575
Synonym: Axid,Acinon,尼扎替丁,Zanizal
Target: AChE, Histamine Receptor
ICI 162,846
Cat.No: T22848
Synonym:
Target: Others
Dalcotidine
Cat.No: T31195
Synonym: KU 1257,KU-1257
Target: Histamine Receptor
Donetidine
Cat.No: T68056
Synonym:
Target: Histamine Receptor
Sufotidine
Cat.No: T68146
Synonym: AH 25352X,AH25352X,AH-25352X
Target: Histamine Receptor
Oxmetidine FA
Cat.No: T68122L
Synonym: Oxmetidine FA(72830-39-8 Free base)
Target: Histamine Receptor
HTMT dimaleate
Cat.No: T22842
Synonym: HTMT马来酸氢盐,Histamine Trifluoromethyl Toluidide Dimaleate
Target: Histamine Receptor
Famotidine
Cat.No: T1627
Synonym: MK-208,法莫替丁
Target: Histamine Receptor
Impromidine hydrochloride
Cat.No: T68921
Synonym:
Target: Histamine Receptor
Mifentidine
Cat.No: T68100
Synonym: DA 4577
Target: Histamine Receptor
BMY 25368 HCl
Cat.No: T23811L
Synonym: BMY 25368 HCl（86134-80-7 Free base)
Target: Histamine Receptor
Dimaprit dihydrochloride
Cat.No: T22724
Synonym:
Target: NOS, NO Synthase, Histamine Receptor
(±)-Tazifylline
Cat.No: T10000
Synonym:
Target: Histamine Receptor
Betazole dihydrochloride
Cat.No: T8599
Synonym: 盐酸倍他唑,Betazole hydrochloride
Target: Histamine Receptor
Oxmetidine
Cat.No: T68122
Synonym: SKF 92994,Oxmetidina,Oxmetidinum
Target: Histamine Receptor
Bismuth Subcitrate Potassium
Cat.No: T6415
Synonym:
Target: SARS-CoV
Alcaftadine
Cat.No: T2533
Synonym: R89674,Lastacaft,阿卡他定
Target: Histamine Receptor
FRG8701
Cat.No: T11324
Synonym:
Target: Histamine Receptor
Tiotidine
Cat.No: T13163
Synonym: ICI 125211
Target: Others
Niperotidine
Cat.No: T12228
Synonym:
Target: Histamine Receptor
Zolantidine dimaleate
Cat.No: T23565
Synonym:
Target: Others
IY-80843
Cat.No: T70297
Synonym:
Target: Others
Zaltidine
Cat.No: T13382
Synonym: CP-57361
Target: Others
IT-066 HCl
Cat.No: T71086
Synonym:
Target: Others
DA 4360
Cat.No: T23941
Synonym: DA4360,DA-4360
Target: Others
Ramixotidine
Cat.No: T26039
Synonym:
Target: Others
BMY-25271
Cat.No: T10575
Synonym:
Target: Histamine Receptor
Orf 17910
Cat.No: T68479
Synonym:
Target: Others
Orf 17583
Cat.No: T68704
Synonym:
Target: Others
DA 4643
Cat.No: T23943
Synonym: DA-4643,DA4643
Target: Others
RP73870
Cat.No: T28613
Synonym: RP 73870,RP-73870
Target: Others
Lavoltidine
Cat.No: T15722
Synonym: Loxtidine,AH-234844
Target: Histamine Receptor
BMY-25368
Cat.No: T23811
Synonym: BMY25368
Target: Others
NO 794
Cat.No: T71529
Synonym:
Target: Others
DA 4626
Cat.No: T23942
Synonym: DA4626,DA-4626
Target: Others
Orf 17578
Cat.No: T68747
Synonym:
Target: Others
Impromidine
Cat.No: T24162
Synonym: Impromidina,Impromidinum
Target: Others
AY 29315
Cat.No: T71390
Synonym:
Target: Others
FCE-27262
Cat.No: T70709
Synonym:
Target: Others
Z 300
Cat.No: T35288
Synonym: Z-300,Z300
Target: Others
Nordimaprit dihydrochloride
Cat.No: T71928
Synonym:
Target: Others
Famotidine hydrochloride
Cat.No: T71470
Synonym:
Target: Others
Famotine
Cat.No: T70127
Synonym:
Target: Others
Famotidine disulfide
Cat.No: T71049
Synonym:
Target: Others
Famotine hydrochloride
Cat.No: T31743
Synonym: Famotine HCl,UK-2054
Target: Others
Species：
Human (2)
Cynomolgus (1)
Expression System：
HEK293 Cells (3)
Tag：
C-His-Avi (2)
C-His (1)
Cat. No. Product Name Species Expression System
TMPK-00193 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated

B7H2,B7RP-1,ICOS ligand,GL50,B7-H2,B7-...

 Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01264 B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)

B7H2,CD275,B7-H2,B7RP1B7-like protein Gl50...

 Cynomolgus HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His...
TMPK-00192 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)

B7RP1B7-like protein Gl50,B7-H2B7-related protein 1...

 Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00193
Species: Human
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01264
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00192
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0189 Ranitidine-d6 HCl

Ranitidine-d6 HCl 是 Ranitidine HCl 的氘代化合物。Ranitidine HCl 的 CAS 号为 66357-59-3。Ranitidine hydrochloride 是一种具有口服活性的组胺 H2 受体选择性拮抗剂，IC50为 3.3 μM。它还是一种CYP2C19和CYP2C9的弱抑制剂，可抑制胃液分泌。

同位素标记化合物

Ranitidine-d6 HCl
Cat.No: TMIJ-0189
Synonym:
Target:
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