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CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 14,900 | 6-8周 | |
50 mg | ¥ 19,420 | 6-8周 | |
100 mg | ¥ 24,625 | 6-8周 |
产品描述 | CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1]. |
体外活性 | CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC 50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively [1]. |
分子量 | 353.85 |
分子式 | C14H12ClN3O2S2 |
CAS No. | 2459916-56-2 |
存储 | Shipping with blue ice. |
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