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TMPY-02585
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Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodiesterase ...
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Mouse
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Baculovirus Insect Cells
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|
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome... |
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TMPY-01813
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ACRV1 Protein, Human, Recombinant (His)
SP-10,SPACA2,D11S4365,acrosomal vesicle protein 1
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Human
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HEK293 Cells
|
|
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr... |
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TMPH-00585
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Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)
Beta-lactamase MEN-1,Cefotaximase 1,bla,men1,Beta-lactamase ...
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E. coli
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P. pastoris (Yeast)
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|
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. |
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TMPH-00584
|
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)
men1,Beta-lactamase MEN-1,Cefotaximase 1,Beta-lactamase CTX-...
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E. coli
|
E. coli
|
|
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. |
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TMPH-01294
|
EDNRA Protein, Human, Recombinant (His)
ET-A,Endothelin-1 receptor,hET-AR,ETA-R,ETRA,EDNRA,ETA
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Human
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P. pastoris (Yeast)
|
|
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
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TMPH-00722
|
PykF Protein, E. coli, Recombinant (His)
Pyruvate kinase I,PK-1,pykF
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E. coli
|
E. coli
|
|
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. |
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TMPJ-00979
|
GSH-S Protein, Human, Recombinant (His)
Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,Glutathione ...
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Human
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E. coli
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|
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon... |
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TMPH-02817
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OTCase Protein, Mouse, Recombinant (His & SUMO)
Ornithine carbamoyltransferase, mitochondrial,Otc,Ornithine ...
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Mouse
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E. coli
|
|
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. |
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TMPJ-00190
|
CD38 Protein, Mouse, Recombinant (hFc)
ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,T10,CD38
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Mouse
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HEK293 Cells
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|
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th... |
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TMPH-00574
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Adenylate cyclase Protein, E. coli, Recombinant (His)
cyaA,EC:4.6.1.1,Adenylyl cyclase,ATP pyrophosphate-lyase
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E. coli
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E. coli
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|
Catalyzes the formation of the second messenger cAMP from ATP. Its transcript is probably degraded by endoribonuclease LS (rnlA), decreasing cAMP levels and the negative regulator Crp-cAMP, which then induces its own transcription again. |
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TMPH-02679
|
QPCT Protein, Mouse, Recombinant (His)
Glutaminyl cyclase,Glutaminyl-tRNA cyclotransferase,Qpct,Glu...
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Mouse
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P. pastoris (Yeast)
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|
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is Q9CYK2. |
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TMPH-00667
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OGDC-E2 Protein, E. coli O157:H7, Recombinant (His)
Dihydrolipoamide succinyltransferase component of 2-oxogluta...
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E. coli
|
E. coli
|
|
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.9 kDa and the accession number is P0AFG7. |
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TMPH-03029
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MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)
Peptidase M,Methionine aminopeptidase,map
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Mycoplasma pneumoniae
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E. coli
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|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. |
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TMPY-02977
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PDE1C Protein, Human, Recombinant (His & GST)
hCam-3,phosphodiesterase 1C, calmodulin-dependent 70kDa,cam-...
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Human
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Baculovirus Insect Cells
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|
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a s... |
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TMPH-00654
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Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)
Methionine aminopeptidase,map,Peptidase M
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E. coli
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E. coli
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|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. |
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TMPH-02905
|
TRPC1 Protein, Mouse, Recombinant (His)
Transient receptor protein 1,Short transient receptor potent...
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Mouse
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E. coli
|
|
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. TRPC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 94.0 kDa and the accession number is Q61056. |
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TMPH-02147
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TACR1 Protein, Human, Recombinant (GST)
Substance-P receptor,Tachykinin receptor 1,NK-1 receptor,TAC...
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Human
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E. coli
|
|
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. TACR1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 30.1 kDa and the accession number is P25103. |
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TMPH-01205
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DCAF7 Protein, Human, Recombinant (His)
DDB1- and CUL4-associated factor 7,WDR68,DCAF7,WD repeat-con...
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Human
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E. coli
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Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
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TMPH-01817
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OTCase Protein, Human, Recombinant (His & SUMO)
Ornithine carbamoyltransferase, mitochondrial,OTC,Ornithine ...
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Human
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E. coli
|
|
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTCase Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is P00480. |
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TMPH-02680
|
QPCT Protein, Mouse, Recombinant (His & Myc)
Glutaminyl cyclase,Qpct,Glutaminyl-peptide cyclotransferase,...
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Mouse
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HEK293 Cells
|
|
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 41.6 kDa and the accession number is Q9CYK2. |
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TMPY-02081
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PDE2A Protein, Human, Recombinant (aa 215-900, His)
phosphodiesterase 2A, cGMP-stimulated,cGSPDE,PED2A4,PDE2A1,C...
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Human
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Baculovirus Insect Cells
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cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 subfamily. Phosphodiesterases (PDEs) comprise a family of enzymes that regulate the levels of cyclic nucleotides, key second messengers that mediate a diverse array of functions. Phosphodiesterases (PDEs) modulate signaling by cyclic nucleotides in diverse processes such as cardiac ... |
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TMPH-03749
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CYSLTR1 Protein, Human, Recombinant (His)
Cysteinyl leukotriene receptor 1,G-protein coupled receptor ...
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Human
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E. coli
|
|
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
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TMPH-01663
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GRM5 Protein, Human, Recombinant (His & Myc)
Metabotropic glutamate receptor 5,GRM5
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Human
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E. coli
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G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
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TMPH-02139
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CYP17A1 Protein, Human, Recombinant (GST)
Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17,S17AH,Cytochrome ...
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Human
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E. coli
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|
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow... |
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TMPH-03018
|
MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)
Peptidase M,map-1,Methionine aminopeptidase 1
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Mycobacterium tuberculosis
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E. coli
|
|
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.9 kDa and the accession ... |
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TMPH-01346
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FPR1 Protein, Human, Recombinant (GST & His & Myc)
FPR1,N-formylpeptide chemoattractant receptor,N-formyl pepti...
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Human
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E. coli
|
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. FPR1 Protein, Human, Recombinant (GST & H... |
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TMPH-02618
|
CYP2E1 Protein, Mouse, Recombinant (His)
Cyp2e1,Cytochrome P450 2E1,Cytochrome P450-J,4-nitrophenol 2...
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Mouse
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E. coli
|
|
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo... |
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TMPH-02141
|
CYP21A2 Protein, Human, Recombinant (His)
Cytochrome P450 21,CYP21A2,Cytochrome P450-C21B,Cytochrome P...
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Human
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P. pastoris (Yeast)
|
|
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via... |
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TMPH-01023
|
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
C5a anaphylatoxin chemotactic receptor 1,C5R1,C5a-R,C5a anap...
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Human
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E. coli
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|
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression syst... |
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TMPH-01022
|
C5AR1 Protein-VLP, Human, Recombinant (His)
C5a anaphylatoxin chemotactic receptor 1,CD88,C5a anaphylato...
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Human
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HEK293 Cells
|
|
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-... |
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TMPJ-01271
|
PIK3IP1 Protein, Human, Recombinant (His)
Kringle domain-containing protein HGFL,PIK3IP1,HGFL
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Human
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HEK293 Cells
|
|
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibrom... |
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TMPK-00370
|
PSMA Protein, Human, Recombinant (hFc)
NAALAdase,FOLH1,FOLHNAALADase I,FGCP,mGCP,PSMAFGCP,NAALADase...
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Human
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HEK293 Cells
|
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Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Human, Recombinant (hFc) is expressed in HEK293 mamma... |
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TMPJ-01117
|
INPP5A Protein, Human, Recombinant (His)
INPP5A,Type I inositol 1,5-trisphosphate 5-phosphatase,Type ...
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Human
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HEK293 Cells
|
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Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. |
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TMPH-03460
|
ERG26 Protein, S. cerevisiae, Recombinant (His & Myc)
ERG26,Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, deca...
|
SVG-Saccharomyces cerevisiae
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E. coli
|
|
Essential enzyme in the ergosterol biosynthetic pathway. Part of a 3 enzyme system that catalyzes the sequential removal of the 2 methyl groups at the sterol C-4 position, converting 4,4-dimethylzymosterol to zymosterol. Catalyzes the second step, an oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group. ERG26 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre... |
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TMPK-00166
|
PD-L2 Protein, Human, Recombinant (His & Avi)
PDL2,Btdc,Butyrophilin B7-DC,PDCD1LG2,bA574F11.2,CD273, PDCD...
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Human
|
HEK293 Cells
|
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession nu... |
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TMPH-01064
|
CCR4 Protein, Human, Recombinant (His & SUMO)
CMKBR4,CD194,K5-5,CCR-4,C-C chemokine receptor type 4,CC-CKR...
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Human
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E. coli
|
|
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expressio... |
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TMPH-02658
|
FPR1 Protein, Mouse, Recombinant (GST & His & Myc)
Fpr1,N-formylpeptide chemoattractant receptor,N-formyl pepti...
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Mouse
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E. coli
|
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. FPR1 Protein, Mouse, Recombinant (GST & H... |
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TMPK-00371
|
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAALAdase,FOL...
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Mouse
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi... |
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TMPK-00941
|
TFF1 Protein, Mouse, Recombinant (hFc)
HP1.A,D21S21,TFF1,Polypeptide P1.A,PS2,BCEI,pNR-2,HPS2,Trefo...
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Mouse
|
HEK293 Cells
|
|
Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Mouse, Recombinant (hFc) is e... |
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TMPH-02140
|
CYP21A2 Protein, Human, Recombinant (E. coli, His)
Cytochrome P-450c21,Cytochrome P450-C21B,CYP21,21-OHase,Cyto...
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Human
|
E. coli
|
|
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via... |
|
TMPH-02677
|
GPI Protein, Mouse, Recombinant (B2M & His)
Gpi,Phosphohexose isomerase,Phosphoglucose isomerase,Neurole...
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Mouse
|
E. coli
|
|
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
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TMPH-00589
|
SpoT Protein, E. coli, Recombinant (His & Myc)
Bifunctional (p)ppGpp synthase/hydrolase SpoT,spoT
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E. coli
|
E. coli
|
|
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small ... |
|
TMPK-00521
|
PSMA Protein, Cynomolgus, Recombinant (His)
PSMA,FOLHNAALADase I,FGCP,GCPII,PSMAFGCP,NAALADase I,PSM,NAA...
|
Cynomolgus
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 ... |
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TMPK-01290
|
PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)
B7DC,PDL2,CD273, PDCD1 ligand 2,Btdc,PDCD1LG2,bA574F11.2,But...
|
Cynomolgus
|
HEK293 Cells
|
|
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the acces... |
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TMPH-01065
|
CCR4 Protein-VLP, Human, Recombinant (His)
CC-CKR-4,CCR4,CCR-4,CD194,C-C chemokine receptor type 4,K5-5...
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Human
|
HEK293 Cells
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High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel... |
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TMPH-02678
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GPI Protein, Mouse, Recombinant (His)
Phosphoglucose isomerase,Autocrine motility factor,Glucose-6...
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Mouse
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P. pastoris (Yeast)
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In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Mous... |
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TMPJ-00732
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ASS1 Protein, Human, Recombinant (His)
Citrulline--Aspartate Ligase,Argininosuccinate Synthase,ASS1...
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Human
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E. coli
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Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin... |
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TMPK-00522
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PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAALADase I,GCPIImGCP...
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Cynomolgus
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HEK293 Cells
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Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His... |
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TMPH-02675
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GCGR Protein, Mouse, Recombinant (GST)
Glucagon receptor,Gcgr
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Mouse
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E. coli
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G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. ... |
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TMPK-00007
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TFF1 Protein, Human, Recombinant (hFc)
Polypeptide P1.A,Trefoil factor 1,Bcei,HP1.A,pNR-2,PS2,HPS2,...
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Human
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HEK293 Cells
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Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death. Establishing an accurate BC prognosis is very difficult because of its heterogeneity. Elevated TFF1 levels in serum were associated with development of BC, TFF1 expression was upregulated in BC compared to the healthy breast tissue.That expression of TFF1 was related to ER status of BC and that expression of TFF1 was lower in TNBC than in non-TNBC. TFF1 Protein, Human, Recombinant (hFc) is e... |
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