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TMPY-00367
|
Chemerin/RARRES2 Protein, Mouse, Recombinant (His)
AI303516,retinoic acid receptor responder (tazarote...
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Mouse
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HEK293 Cells
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|
Chemerin/RARRES2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q9DD06. |
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TMPY-00190
|
ULBP-6 Protein, Human, Recombinant (hFc)
retinoic acid early transcript 1L,RAET1L,ULBP6
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Human
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HEK293 Cells
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ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cel... |
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TMPH-00378
|
Midkine Protein, Chicken, Recombinant (His & Myc)
Midkine,RIHB,Retinoic acid-induced heparin-binding ...
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Chicken
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E. coli
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|
Has mitogenic activity, and neurite extension activity for PC12 cells. Midkine Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is P24052. |
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TMPY-00575
|
ULBP-6 Protein, Human, Recombinant (His)
RAET1L,retinoic acid early transcript 1L,ULBP6
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Human
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HEK293 Cells
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ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel... |
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TMPY-04143
|
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)
0610007L05Rik,retinoic acid receptor responder (taz...
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Mouse
|
HEK293 Cells
|
|
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.6 kDa and the accession number is Q9DD06. |
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TMPY-02189
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CRABP2 Protein, Mouse, Recombinant (His)
Crabp-2,cellular retinoic acid binding protein 2,AI...
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Mouse
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E. coli
|
|
CRABP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.1 kDa and the accession number is P22935. |
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TMPY-01549
|
CRABP2 Protein, Human, Recombinant (His)
RBP6,cellular retinoic acid binding protein 2,CRABP...
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Human
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E. coli
|
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CRABP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P29373. |
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TMPY-03864
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CRABP1 Protein, Human, Recombinant
CRABP,CRABP-I,RBP5,cellular retinoic acid binding p...
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Human
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E. coli
|
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CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. It forms a beta-barrel structure which accommodates hydrophobic ligands in its interior. |
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TMPH-01183
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CYP26B1 Protein, Human, Recombinant (His)
Cytochrome P450 26A2,CYP26B1,P450RAI2,Cytochrome P450 26B1,<...
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Human
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E. coli
|
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CYP26B1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.5 kDa and the accession number is Q9NR63. |
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TMPY-00194
|
ULBP-4 Protein, Human, Recombinant (His)
N2DL-4,RAET1E2,ULBP4,LETAL,RL-4,retinoic acid early...
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Human
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HEK293 Cells
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The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q8TD07-1. |
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TMPH-02032
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GPRC5A Protein, Human, Recombinant (GST)
G-protein coupled receptor family C group 5 member A,GPRC5A,...
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Human
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E. coli
|
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Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor. GPRC5A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.0 kDa and the accession number i... |
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TMPY-00193
|
ULBP-4 Protein, Human, Recombinant (hFc)
LETAL,bA350J20.7,RL-4,RAET1E2,retinoic acid early t...
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Human
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HEK293 Cells
|
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The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q8TD07-1. |
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TMPH-00941
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RIG-I Protein, Human, Recombinant (His)
RIGI,DEAD box protein 58,Antiviral innate immune response re...
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Human
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E. coli
|
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RIG-I Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is O95786. |
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TMPJ-00131
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NKG2DL Protein, Human, Recombinant (hFc)
ALCAN-β,NKG2DL1,UL16-binding protein 1,NKG2D ligand 1,ULBP1,...
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Human
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HEK293 Cells
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NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess α1, α2 and α3 domains, ULBP/RAET1 family members lack α3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells, and then promotes the lysis of cells expressing ULBP1 which is important for the im... |
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TMPJ-01292
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Chemerin/RARRES2 Protein, Human, Recombinant (His)
RAR-responsive protein TIG2,RARRES2,Chemerin,Tazarotene-indu...
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Human
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HEK293 Cells
|
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Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thou... |
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TMPH-02006
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STRA6 Protein, Human, Recombinant (hFc)
STRA6,Retinol-binding protein receptor STRA6,Receptor for re...
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Human
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HEK293 Cells
|
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STRA6 Protein, Human, Recombinant (hFc) is expressed in HEK293. |
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TMPH-01619
|
LY6E Protein, Human, Recombinant (His & SUMO)
LY6E,Thymic shared antigen 1,Stem cell antigen 2,Lymphocyte ...
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Human
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E. coli
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LY6E Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is Q16553. |
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TMPY-06986
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FGF-8b Protein, Human, Recombinant
NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...
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Human
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E. coli
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In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... |
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TMPY-00005
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FGF-8a Protein, Human, Recombinant
fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...
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Human
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E. coli
|
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In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... |
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TMPH-01650
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PRAME Protein, Human, Recombinant (E. coli, His)
Opa-interacting protein 4,Preferentially expressed antigen o...
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Human
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E. coli
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Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation. The CRL2(PRAME) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding. In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role... |
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TMPH-02518
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APOM Protein, Mouse, Recombinant (His)
Ng20,ApoM,Apolipoprotein M,Apo-M
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Mouse
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P. pastoris (Yeast)
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Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. APOM Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.3 kDa and the accession number is Q9Z1R3. |
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TMPJ-00900
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TGM2 Protein, Mouse, Recombinant (His)
Transglutaminase C,Tgm2,Tissue transglutaminase,TGase-2,Prot...
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Mouse
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HEK293 Cells
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Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. |
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TMPK-01014
|
ULBP-6 Protein, Human, Recombinant (aa 26-218, hFc)
RAET1L,ULBP6
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Human
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HEK293 Cells
|
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ULBP6/RAET1L (UL16-binding protein, also known as retinoic acid early transcript), is expressed as a full-lengthtranscript in cells and encodes a protein that is a ligand for bothNKG2D and the UL16 protein of HCMV. |
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TMPH-02221
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TRIM24 Protein, Human, Recombinant (His & SUMO)
Transcription intermediary factor 1-alpha,E3 ubiquitin-prote...
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Human
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E. coli
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Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apopt... |
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TMPH-00464
|
Fibin Protein, Danio rerio, Recombinant (His)
Fin bud initiation factor,fibin
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Danio rerio (Zebrafish)
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E. coli
|
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Essential for the initiation of pectoral fin bud formation. Potentially acts downstream of retinoic acid and Wnt signaling and is required for tbx5 expression in the lateral plate mesoderm of presumptive pectoral fin bud regions. Fibin Protein, Danio rerio, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.0 kDa and the accession number is A1IGX5. |
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TMPJ-01213
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ASXL1 Protein, Human, Recombinant (GST)
Putative Polycomb group protein ASXL1,Additional sex combs-l...
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Human
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E. coli
|
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Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 t... |
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TMPK-00023
|
Midkine Protein, Human, Recombinant (His & Avi)
MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2
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Human
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E. coli
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Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu... |
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TMPK-00024
|
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP
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Human
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E. coli
|
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Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu... |
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TMPK-00812
|
Midkine Protein, Mouse, Recombinant (His)
MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK
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Mouse
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E. coli
|
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Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo... |
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TMPJ-00953
|
ADH7 Protein, Human, Recombinant (His)
Retinol Dehydrogenase,Alcohol Dehydrogenase Class 4 μ/σ Chai...
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Human
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HEK293 Cells
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Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good subst... |
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TMPJ-00710
|
ALDH1A2 Protein, Human, Recombinant (His)
RALDH(II),Retinal dehydrogenase 2,RALDH2,ALDH1A2,Retinaldehy...
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Human
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E. coli
|
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Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma... |
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TMPY-02172
|
Midkine Protein, Human, Recombinant
midkine (neurite growth-promoting factor 2),NEGF2,MK,ARAP
|
Human
|
Baculovirus Insect Cells
|
|
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angio... |
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TMPY-00585
|
Annexin A8 Protein, Human, Recombinant (His)
ANX8,annexin A8
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Human
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E. coli
|
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We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA8 mRNA is expressed in low-proliferative isolated pubertal mouse mammary ductal epithelium and after enforced involution, but not in isolated highly proliferative terminal end buds (TEB) or during pregnancy. ANXA8 as a potential mediator of quiescence in the normal mouse mammary ... |
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TMPY-01416
|
OLFM4 Protein, Human, Recombinant (His)
hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...
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Human
|
HEK293 Cells
|
|
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed... |
|
TMPY-01583
|
ALDH1A1 Protein, Human, Recombinant (His)
ALDH11,ALDC,PUMB1,ALDH-E1,HEL-S-53e,HEL-9,aldehyde dehydroge...
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Human
|
E. coli
|
|
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f... |
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TMPH-02832
|
Serpin A5 Protein, Mouse, Recombinant (His)
Protein C inhibitor,Plasminogen activator inhibitor 3,Serpin...
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Mouse
|
Baculovirus Insect Cells
|
|
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple... |
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